NEO vs CAI vs GH Stock Comparison

Neogenomics, Caris Life Sciences and Guardant Health Prices as of Oct 28, 2026 Peers: Industry group
NEO Neogenomics Inc
$17.99 -6.7% 1M +81.4% 1Y
Market cap
$2.32B
P/E
–
Revenue (TTM)
$787.75M
Div. yield
–
Diagnostic Labs Healthcare
2 wins
CAI Caris Life Sciences, Inc.
$35.45 +11.7% 1M +16.7% 1Y
Market cap
$10.02B
P/E
95.4x
Revenue (TTM)
$989.61M
Div. yield
–
Diagnostic Labs Healthcare
3 wins
GH Guardant Health, Inc.
$182.59 +3.0% 1M +162.4% 1Y
Market cap
$24.40B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

8 decided of 12

Guardant Health leads on 3 of the 12 questions below (Guardant Health 3, Caris Life Sciences 3, Neogenomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionNEOCAIGHLeader
Larger companyMarket capitalisation $2.32B $10.02B $24.40B GH
Cheaper on earningsLower P/E, profitable companies only -71.6x 95.4x -53.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 89.9x 322.3x — NEO
Faster revenue growthRevenue growth, trailing twelve months +11.1% +85.4% +42.7% CAI
More profitableNet margin, trailing twelve months -4.1% 10.6% -38.3% CAI
Better return on capitalReturn on invested capital — 15.6% — –
Less leveragedLower net debt / EBITDA — -2.2x — –
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months +81.4% +16.7% +162.4% GH
Better 5-year returnAnnualised price return, 5 years -17.1%/yr — +9.4%/yr GH
Less volatileAnnualised volatility, 1 year 53.8% 69.7% 57.3% NEO
Higher overall scoreMean of the five percentile scores vs peers 42/100 70/100 28/100 CAI

Percentile Scorecard

NEOCAIGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisNEOCAIGH
Valuation 32 #63 of 92 24 #70 of 92 18 #76 of 92
Growth 57 #38 of 87 99 #2 of 87 48 #46 of 87
Profitability 33 #58 of 86 91 #9 of 86 7 #80 of 86
Financial Health 71 #29 of 97 81 #19 of 97 53 #46 of 97
Shareholder Returns 19 #45 of 55 56 #25 of 55 15 #47 of 55
Overall 42 70 28
  • NEO ranked among 102 companies in Healthcare Providers
  • CAI ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodNEOCAIGHSPY
1 month -6.7%+11.7%+3.0% +0.9%
3 months +17.8%+127.4%+26.7% +5.9%
6 months +100.8%+99.5%+118.9% +8.5%
Year to date +53.0%+31.4%+78.8% +13.3%
1 year +81.4%+16.7%+162.4% +12.4%
3 years +32.2%—+631.5% +88.1%
3 years, per year +9.8%—+94.2% +23.5%
5 years -60.9%—+56.3% +68.2%
5 years, per year -17.1%—+9.4% +11.0%
10 years +123.5%—— +263.4%
10 years, per year +8.4%—— +13.8%

Risk

MeasureNEOCAIGHSPY
Volatility, 1Y 53.8%69.7%57.3% 12.7%
Downside volatility, 1Y 53.5%69.3%48.9% 12.7%
Beta vs S&P 500, 1Y 1.071.401.04 1.00
Return / volatility, 1Y 1.510.242.83 0.98
Max drawdown, 5Y -89.7%-63.0%-86.7% -25.4%
From 52-week high -9.6%0.0%-2.5% -0.9%
52-week high $19.91$35.45$187.22 $779.14
52-week low $7.19$14.55$69.58 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleNEOCAIGH
P/E now vs peer median -71.6xmedian 25.6x 95.4xmedian 25.6x -53.5xmedian 25.6x
P/S now vs peer median 2.9xmedian 1.6x 10.1xmedian 1.6x 20.6xmedian 1.6x
EV/EBITDA now vs peer median 130.9xmedian 16.3x 53.4xmedian 16.3x -54.1xmedian 16.3x
P/FCF now vs peer median -81.3xmedian 21.3x 80.8xmedian 21.3x -101.3xmedian 21.3x
P/B now vs peer median 2.9xmedian 3.3x 16.9xmedian 3.3x -109.5xmedian 3.3x
PEG now vs peer median -2.31median 0.68 —median 0.68 -5.39median 0.68

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsNEOCAIGH
Revenue $787.75M $989.61M $1.18B
Gross profit $352.67M $689.36M $769.16M
Operating income -$49.37M $153.26M -$470.26M
Net income -$32.30M $105.14M -$453.44M
Free cash flow -$28.58M $123.96M -$240.72M
R&D $39.33M $117.14M $375.79M
EPS (diluted) $-0.25 $0.37 $-3.41
Cash & equivalents $139.28M $690.92M $1.05B
Total debt – $393.15M –
Shares (diluted) 128.59M 282.89M 132.87M
Enterprise value $1.73B $6.84B $20.46B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricNEOCAIGH
P/E -71.6x 95.4x -53.5x
P/FCF -81.3x 80.8x -101.3x
P/Operating cash flow 542.6x 59.4x -131.7x
P/S 2.9x 10.1x 20.6x
P/B 2.9x 16.9x -109.5x
P/Tangible book 4.3x 16.9x -98.3x
EV/EBITDA 130.9x 53.4x -54.1x
EV/EBIT -44.2x 62.8x -49.6x
EV/Revenue 2.8x 9.7x 19.7x
EV/FCF -76.4x 77.6x -97.0x
EV/Operating cash flow 510.1x 57.1x -126.1x
PEG (3Y EPS CAGR) -2.31 – -5.39

Growth

14 metrics
MetricNEOCAIGH
Revenue growth (1Y) 11.1% 85.4% 42.7%
Revenue CAGR (3Y) 11.1% – 32.4%
Gross profit growth (1Y) 14.4% 141.2% 47.7%
Gross profit CAGR (3Y) 14.7% – –
Operating income growth (1Y) 59.2% 188.2% -2.1%
Operating income CAGR (3Y) 24.7% – 4.8%
Net income growth (1Y) 71.5% 137.7% -9.6%
Net income CAGR (3Y) 30.5% – 3.7%
EPS growth (1Y) 71.6% 103.0% -2.4%
EPS CAGR (3Y) 31.1% – 9.9%
Operating cash flow growth (1Y) -68.7% 227.3% 22.4%
Operating cash flow CAGR (3Y) 29.7% – 18.1%
Free cash flow growth (1Y) -67.7% 188.2% 11.4%
Free cash flow CAGR (3Y) 16.8% – 14.4%

Profitability

14 metrics
MetricNEOCAIGH
Gross margin 44.8% 69.7% 65.0%
EBITDA margin 2.1% 18.2% -36.5%
Operating margin -6.3% 15.5% -39.7%
Pretax margin -4.6% 10.6% -38.4%
Net margin -4.1% 10.6% -38.3%
FCF margin -3.6% 12.5% -20.3%
Operating cash flow margin 0.5% 17.0% -15.7%
Return on equity -4.1% 17.7% –
Return on assets -2.4% 8.8% -23.7%
Return on invested capital – 15.6% –
Return on capital employed -4.0% 15.3% -29.9%
Asset turnover 0.6x 0.8x 0.6x
Cash conversion (OCF / net income) -0.1x 1.6x 0.4x
Stock comp / revenue 4.4% 6.6% 16.2%

Financial Health

11 metrics
MetricNEOCAIGH
Debt / assets – 32.0% –
Debt / equity – 0.7x –
Net debt / EBITDA – -2.2x –
Debt / FCF – 3.2x –
Liabilities / assets 41.9% 51.9% 111.7%
Equity / assets 58.1% 48.1% -11.7%
Interest coverage -15.2x 3.3x -97.6x
Current ratio 3.5x 5.5x 4.0x
Quick ratio 3.0x 4.8x 3.5x
Cash ratio 1.2x 4.1x 3.1x
Altman Z-score 2.66 8.58 4.94

Shareholder Returns

7 metrics
MetricNEOCAIGH
Dividend yield – – –
Net buyback yield -0.6% 0.1% -1.6%
Shareholder yield -0.6% 0.1% -1.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusNEOCAIGH
Forward P/E 89.9xFY2026 322.3xFY2026 –
EPS, next fiscal year $0.20FY2026 $0.11FY2026 $-3.33FY2026
EPS growth, next FY +66.7%FY2026 – –
EPS growth, the year after +80.0% +236.4% –
Revenue, next fiscal year $778.61MFY2026 $1.06BFY2026 $1.42BFY2026
Revenue growth, next FY +7.1%FY2026 +30.1%FY2026 +44.5%FY2026
Revenue growth, the year after +6.5% +21.6% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersNEOCAIGH
Held by institutions 100.0% 52.0% 100.0%
Institutions holding 266 245 594
Change in shares held, QoQ +8.1% -6.3% -2.6%
Institutions buying 156 175 353
Institutions selling 62 47 180
Buyers to sellers 2.52 3.72 1.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

NEOCAIGH
NEO 1.00 0.42 0.38
CAI 0.42 1.00 0.42
GH 0.38 0.42 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, NEO, CAI and GH?

Guardant Health (GH) is the largest by market capitalisation: Neogenomics (NEO) $2.32B, Caris Life Sciences (CAI) $10.02B, Guardant Health (GH) $24.40B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Neogenomics (NEO) +11.1%, Caris Life Sciences (CAI) +85.4%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Neogenomics (NEO) -4.1%, Caris Life Sciences (CAI) 10.6%, Guardant Health (GH) -38.3%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Neogenomics (NEO) +81.4%, Caris Life Sciences (CAI) +16.7%, Guardant Health (GH) +162.4%. Over five years, Guardant Health (GH) compounded fastest (Neogenomics (NEO) -17.1%/yr, Guardant Health (GH) +9.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Neogenomics (NEO) has been the steadiest (Neogenomics (NEO) 53.8%, Caris Life Sciences (CAI) 69.7%, Guardant Health (GH) 57.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, NEO, CAI and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.