MRNA vs REGN vs ALNY Stock Comparison

Moderna, Regeneron Pharmaceuticals and Alnylam Pharmaceuticals Prices as of Oct 27, 2026 Peers: Industry group
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$85.10B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Alnylam Pharmaceuticals 3, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMRNAREGNALNYLeader
Larger companyMarket capitalisation $85.10B $83.63B $31.06B MRNA
Cheaper on earningsLower P/E, profitable companies only -27.0x 19.3x 42.4x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 14.3x 33.5x REGN
Faster revenue growthRevenue growth, trailing twelve months -27.6% +9.3% +90.1% ALNY
More profitableNet margin, trailing twelve months -141.4% 27.9% 15.3% REGN
Better return on capitalReturn on invested capital -43.3% 9.6% — REGN
Less leveragedLower net debt / EBITDA 1.5x -1.4x — REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +680.1% +39.4% -52.6% MRNA
Better 5-year returnAnnualised price return, 5 years -9.8%/yr +5.5%/yr +6.9%/yr ALNY
Less volatileAnnualised volatility, 1 year 130.8% 32.8% 51.2% REGN
Higher overall scoreMean of the five percentile scores vs peers 57/100 72/100 77/100 ALNY

Percentile Scorecard

MRNAREGNALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMRNAREGNALNY
Valuation 69 #193 of 625 89 #71 of 625 81 #118 of 625
Growth 18 #493 of 602 42 #351 of 602 98 #13 of 602
Profitability 57 #239 of 551 90 #54 of 551 93 #41 of 551
Financial Health 55 #298 of 656 74 #172 of 656 45 #359 of 656
Shareholder Returns 85 #57 of 365 65 #129 of 365 67 #121 of 365
Overall 57 72 77
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ALNY ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMRNAREGNALNYSPY
1 month +4.6%+3.6%-11.4% -0.2%
3 months +272.6%+17.4%-21.4% +3.9%
6 months +341.2%+11.5%-24.9% +8.2%
Year to date +605.2%+5.7%-43.0% +12.9%
1 year +680.1%+39.4%-52.6% +12.3%
3 years +189.2%+5.3%+49.4% +87.4%
3 years, per year +42.5%+1.7%+14.3% +23.3%
5 years -40.2%+30.5%+39.9% +67.9%
5 years, per year -9.8%+5.5%+6.9% +10.9%
10 years —+123.4%+526.3% +261.1%
10 years, per year —+8.4%+20.1% +13.7%

Risk

MeasureMRNAREGNALNYSPY
Volatility, 1Y 130.8%32.8%51.2% 12.7%
Downside volatility, 1Y 79.5%30.0%62.6% 12.7%
Beta vs S&P 500, 1Y 2.150.470.34 1.00
Return / volatility, 1Y 5.201.20-1.03 0.97
Max drawdown, 5Y -93.9%-59.8%-58.2% -25.4%
From 52-week high -15.4%-4.2%-52.9% -1.2%
52-week high $245.81$852.03$481.59 $779.14
52-week low $22.36$585.31$205.48 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMRNAREGNALNY
P/E now vs peer median -26.3xmedian 17.2x 19.4xmedian 17.2x 41.3xmedian 17.2x
P/S now vs peer median 37.2xmedian 9.0x 5.4xmedian 9.0x 6.3xmedian 9.0x
EV/EBITDA now vs peer median -25.5xmedian 16.3x 17.8xmedian 16.3x 25.6xmedian 16.3x
P/FCF now vs peer median -66.7xmedian 18.7x 22.3xmedian 18.7x 37.0xmedian 18.7x
P/B now vs peer median 12.3xmedian 2.2x 2.6xmedian 2.2x 22.4xmedian 2.2x
PEG now vs peer median 0.40median 0.33 7.29median 0.33 1.09median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMRNAREGNALNY
Revenue $2.23B $15.53B $4.80B
Gross profit $521.00M $13.18B $3.83B
Operating income -$3.32B $3.84B $999.78M
Net income -$3.15B $4.33B $733.11M
Free cash flow -$1.24B $3.76B $819.87M
R&D $2.88B $6.28B $1.51B
EPS (diluted) $-7.92 $40.84 $5.30
Cash & equivalents $1.72B $2.46B $1.71B
Total debt $591.00M $1.99B –
Shares (diluted) 398.00M 106.00M 138.28M
Enterprise value $64.46B $49.83B $19.11B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMRNAREGNALNY
P/E -26.3x 19.4x 41.3x
P/FCF -66.7x 22.3x 37.0x
P/Operating cash flow -77.3x 17.9x 33.3x
P/S 37.2x 5.4x 6.3x
P/B 12.3x 2.6x 22.4x
P/Tangible book 12.3x 2.8x 22.4x
EV/EBITDA -25.5x 17.8x 25.6x
EV/EBIT -23.6x 20.3x 27.0x
EV/Revenue 35.2x 5.0x 5.6x
EV/FCF -63.0x 20.7x 33.0x
EV/Operating cash flow -73.1x 16.6x 29.6x
PEG (3Y EPS CAGR) 0.40 7.29 1.09

Growth

14 metrics
MetricMRNAREGNALNY
Revenue growth (1Y) -27.6% 9.3% 90.1%
Revenue CAGR (3Y) -40.6% 7.0% 57.2%
Gross profit growth (1Y) -67.8% 8.4% 79.7%
Gross profit CAGR (3Y) -56.0% 6.4% 54.6%
Operating income growth (1Y) -1.4% 0.1% 654.9%
Operating income CAGR (3Y) -103.9% -3.9% 47.5%
Net income growth (1Y) -8.5% -2.9% 356.5%
Net income CAGR (3Y) -66.4% 0.2% 39.1%
EPS growth (1Y) -5.8% -0.5% 342.3%
EPS CAGR (3Y) -65.1% 2.7% 37.9%
Operating cash flow growth (1Y) 60.2% -1.3% 2,299%
Operating cash flow CAGR (3Y) -68.1% -0.4% 57.8%
Free cash flow growth (1Y) 64.4% -2.4% 1,151%
Free cash flow CAGR (3Y) -18.2% -3.3% 52.1%

Profitability

14 metrics
MetricMRNAREGNALNY
Gross margin 23.4% 84.9% 79.8%
EBITDA margin -138.2% 28.1% 22.0%
Operating margin -149.0% 24.7% 20.8%
Pretax margin -138.6% 33.3% 16.0%
Net margin -141.4% 27.9% 15.3%
FCF margin -55.8% 24.2% 17.1%
Operating cash flow margin -48.2% 30.1% 19.0%
Return on equity -44.5% 13.7% 63.8%
Return on assets -28.1% 10.5% 14.5%
Return on invested capital -43.3% 9.6% –
Return on capital employed -38.2% 10.7% 26.1%
Asset turnover 0.2x 0.4x 0.9x
Cash conversion (OCF / net income) 0.3x 1.1x 1.2x
Stock comp / revenue 20.7% 6.4% 7.0%

Financial Health

11 metrics
MetricMRNAREGNALNY
Debt / assets 5.4% 4.8% –
Debt / equity 0.1x 0.1x –
Net debt / EBITDA 1.5x -1.4x –
Debt / FCF -0.5x 0.5x –
Liabilities / assets 38.3% 24.0% 75.6%
Equity / assets 61.7% 76.0% 24.4%
Interest coverage – 69.4x 3.8x
Current ratio 2.3x 3.3x 3.1x
Quick ratio 2.0x 2.6x 2.8x
Cash ratio 2.0x 1.4x 2.2x
Altman Z-score 12.07 7.33 4.86

Shareholder Returns

7 metrics
MetricMRNAREGNALNY
Dividend yield – 0.5% –
Net buyback yield -0.1% 3.0% -0.5%
Shareholder yield -0.1% 3.5% -0.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMRNAREGNALNY
Forward P/E – 14.3xFY2026 33.5xFY2026
EPS, next fiscal year $-8.02FY2026 $57.08FY2026 $6.76FY2026
EPS growth, next FY – +28.8%FY2026 +190.1%FY2026
EPS growth, the year after – +15.5% +34.3%
Revenue, next fiscal year $2.04BFY2026 $17.05BFY2026 $5.68BFY2026
Revenue growth, next FY +5.1%FY2026 +18.9%FY2026 +53.1%FY2026
Revenue growth, the year after +26.8% +13.0% +27.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMRNAREGNALNY
Held by institutions 80.2% 66.2% 99.7%
Institutions holding 784 1,325 786
Change in shares held, QoQ +3.4% +3.8% +3.8%
Institutions buying 402 604 412
Institutions selling 238 534 277
Buyers to sellers 1.69 1.13 1.49

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MRNAREGNALNY
MRNA 1.00 0.26 0.21
REGN 0.26 1.00 0.14
ALNY 0.21 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MRNA, REGN and ALNY?

Moderna (MRNA) is the largest by market capitalisation: Moderna (MRNA) $85.10B, Regeneron Pharmaceuticals (REGN) $83.63B, Alnylam Pharmaceuticals (ALNY) $31.06B.

Which stock is cheaper, MRNA, REGN and ALNY?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (Moderna (MRNA) -27.0x, Regeneron Pharmaceuticals (REGN) 19.3x, Alnylam Pharmaceuticals (ALNY) 42.4x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Regeneron Pharmaceuticals (REGN) 14.3x, Alnylam Pharmaceuticals (ALNY) 33.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Moderna (MRNA) -27.6%, Regeneron Pharmaceuticals (REGN) +9.3%, Alnylam Pharmaceuticals (ALNY) +90.1%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Moderna (MRNA) -141.4%, Regeneron Pharmaceuticals (REGN) 27.9%, Alnylam Pharmaceuticals (ALNY) 15.3%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Moderna (MRNA) -43.3%, Regeneron Pharmaceuticals (REGN) 9.6%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Moderna (MRNA) +680.1%, Regeneron Pharmaceuticals (REGN) +39.4%, Alnylam Pharmaceuticals (ALNY) -52.6%. Over five years, Alnylam Pharmaceuticals (ALNY) compounded fastest (Moderna (MRNA) -9.8%/yr, Regeneron Pharmaceuticals (REGN) +5.5%/yr, Alnylam Pharmaceuticals (ALNY) +6.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (Moderna (MRNA) 130.8%, Regeneron Pharmaceuticals (REGN) 32.8%, Alnylam Pharmaceuticals (ALNY) 51.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MRNA, REGN and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.