MRNA vs AMGN vs ARGX Stock Comparison

Moderna, Amgen and Argenx Se Prices as of Oct 27, 2026 Peers: Industry group
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$85.53B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins
AMGN Amgen Inc
$447.95 +8.0% 1M +53.9% 1Y
Market cap
$243.49B
P/E
27.8x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
5 wins
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.42B
P/E
29.0x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

11 decided of 12

Amgen leads on 5 of the 12 questions below (Amgen 5, Argenx Se 4, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMRNAAMGNARGXLeader
Larger companyMarket capitalisation $85.53B $243.49B $54.42B AMGN
Cheaper on earningsLower P/E, profitable companies only -27.1x 27.8x 29.0x AMGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 20.5x 28.8x AMGN
Faster revenue growthRevenue growth, trailing twelve months -27.6% +9.1% +61.5% ARGX
More profitableNet margin, trailing twelve months -141.4% 23.0% 32.3% ARGX
Better return on capitalReturn on invested capital -43.3% 14.3% — AMGN
Less leveragedLower net debt / EBITDA 1.5x 2.7x — MRNA
Higher dividend yieldTrailing dividend yield 0.00% 0.02% 0.00% –
Better 1-year returnPrice return, last 12 months +680.1% +53.9% +6.3% MRNA
Better 5-year returnAnnualised price return, 5 years -9.8%/yr +16.7%/yr +25.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 130.8% 29.6% 36.9% AMGN
Higher overall scoreMean of the five percentile scores vs peers 57/100 66/100 92/100 ARGX

Percentile Scorecard

MRNAAMGNARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMRNAAMGNARGX
Valuation 69 #193 of 625 86 #90 of 625 84 #99 of 625
Growth 18 #493 of 602 62 #231 of 602 94 #35 of 602
Profitability 57 #239 of 551 95 #31 of 551 98 #11 of 551
Financial Health 55 #298 of 656 22 #510 of 656 –
Shareholder Returns 85 #57 of 365 68 #117 of 365 –
Overall 57 66 92
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMRNAAMGNARGXSPY
1 month +4.6%+8.0%-8.0% -0.2%
3 months +272.6%+14.0%+1.2% +3.9%
6 months +341.2%+31.9%+13.9% +8.2%
Year to date +605.2%+36.9%+4.9% +12.9%
1 year +680.1%+53.9%+6.3% +12.3%
3 years +189.2%+71.3%+91.9% +87.4%
3 years, per year +42.5%+19.7%+24.3% +23.3%
5 years -40.2%+116.2%+214.2% +67.9%
5 years, per year -9.8%+16.7%+25.8% +10.9%
10 years —+179.0%— +261.1%
10 years, per year —+10.8%— +13.7%

Risk

MeasureMRNAAMGNARGXSPY
Volatility, 1Y 130.8%29.6%36.9% 12.7%
Downside volatility, 1Y 79.5%27.9%34.6% 12.7%
Beta vs S&P 500, 1Y 2.150.460.39 1.00
Return / volatility, 1Y 5.201.820.17 0.97
Max drawdown, 5Y -93.9%-26.7%-38.2% -25.4%
From 52-week high -15.4%0.0%-16.7% -1.2%
52-week high $245.81$447.95$1,058.90 $779.14
52-week low $22.36$291.16$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMRNAAMGNARGX
P/E now vs peer median -26.3xmedian 17.2x 27.7xmedian 17.2x 28.8xmedian 17.2x
P/S now vs peer median 37.2xmedian 9.0x 6.4xmedian 9.0x 9.4xmedian 9.0x
EV/EBITDA now vs peer median -25.5xmedian 16.3x 17.7xmedian 16.3x —median 16.3x
P/FCF now vs peer median -66.7xmedian 18.7x 23.8xmedian 18.7x —median 18.7x
P/B now vs peer median 12.3xmedian 2.2x 20.7xmedian 2.2x —median 2.2x
PEG now vs peer median 0.40median 0.33 10.44median 0.33 0.27median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMRNAAMGNARGX
Revenue $2.23B $38.10B $5.82B
Gross profit $521.00M $26.48B $5.24B
Operating income -$3.32B $11.43B $1.74B
Net income -$3.15B $8.74B $1.88B
Free cash flow -$1.24B $10.18B –
R&D $2.88B $7.63B $1.80B
EPS (diluted) $-7.92 $16.07 $28.43
Cash & equivalents $1.72B $13.99B –
Total debt $591.00M $57.30B –
Shares (diluted) 398.00M 544.00M 66.03M
Enterprise value $64.88B $198.89B $54.42B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMRNAAMGNARGX
P/E -26.3x 27.7x 28.8x
P/FCF -66.7x 23.8x –
P/Operating cash flow -77.3x 19.4x –
P/S 37.2x 6.4x 9.4x
P/B 12.3x 20.7x –
P/Tangible book 12.3x -27.5x –
EV/EBITDA -25.5x 17.7x –
EV/EBIT -23.6x 25.0x 31.4x
EV/Revenue 35.2x 7.5x 9.4x
EV/FCF -63.0x 28.1x –
EV/Operating cash flow -73.1x 22.9x –
PEG (3Y EPS CAGR) 0.40 10.44 0.27

Growth

14 metrics
MetricMRNAAMGNARGX
Revenue growth (1Y) -27.6% 9.1% 61.5%
Revenue CAGR (3Y) -40.6% 12.7% 80.5%
Gross profit growth (1Y) -67.8% 17.6% 62.2%
Gross profit CAGR (3Y) -56.0% 10.3% 80.0%
Operating income growth (1Y) -1.4% 39.5% 120.6%
Operating income CAGR (3Y) -103.9% 6.4% 85.1%
Net income growth (1Y) -8.5% 32.1% 22.5%
Net income CAGR (3Y) -66.4% 3.1% 115.5%
EPS growth (1Y) -5.8% 31.4% 20.9%
EPS CAGR (3Y) -65.1% 2.7% 104.8%
Operating cash flow growth (1Y) 60.2% 3.9% –
Operating cash flow CAGR (3Y) -68.1% 4.9% –
Free cash flow growth (1Y) 64.4% -4.1% –
Free cash flow CAGR (3Y) -18.2% 1.7% –

Profitability

14 metrics
MetricMRNAAMGNARGX
Gross margin 23.4% 69.5% 90.0%
EBITDA margin -138.2% 42.2% –
Operating margin -149.0% 30.0% 29.9%
Pretax margin -138.6% 27.0% 32.6%
Net margin -141.4% 23.0% 32.3%
FCF margin -55.8% 26.7% –
Operating cash flow margin -48.2% 32.8% –
Return on equity -44.5% 83.8% –
Return on assets -28.1% 9.3% –
Return on invested capital -43.3% 14.3% –
Return on capital employed -38.2% 16.7% –
Asset turnover 0.2x 0.4x –
Cash conversion (OCF / net income) 0.3x 1.4x –
Stock comp / revenue 20.7% 1.3% –

Financial Health

11 metrics
MetricMRNAAMGNARGX
Debt / assets 5.4% 59.9% –
Debt / equity 0.1x 4.9x –
Net debt / EBITDA 1.5x 2.7x –
Debt / FCF -0.5x 5.6x –
Liabilities / assets 38.3% 87.8% –
Equity / assets 61.7% 12.2% –
Interest coverage – 4.3x 10,120x
Current ratio 2.3x 1.4x –
Quick ratio 2.0x 0.9x –
Cash ratio 2.0x 0.5x –
Altman Z-score 12.07 2.32 –

Shareholder Returns

7 metrics
MetricMRNAAMGNARGX
Dividend yield – 2.2% –
Net buyback yield -0.1% – –
Shareholder yield -0.1% 2.2% –
Payout ratio (earnings) – 60.4% –
Payout ratio (FCF) – 51.9% –
Dividend growth (1Y) – 6.3% –
Dividend CAGR (3Y) – 6.7% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMRNAAMGNARGX
Forward P/E – 20.5xFY2026 28.8xFY2026
EPS, next fiscal year $-8.02FY2026 $21.81FY2026 $30.63FY2026
EPS growth, next FY – -0.1%FY2026 +56.5%FY2026
EPS growth, the year after – +7.2% +26.9%
Revenue, next fiscal year $2.04BFY2026 $41.51BFY2026 $6.08BFY2026
Revenue growth, next FY +5.1%FY2026 +12.9%FY2026 +43.1%FY2026
Revenue growth, the year after +26.8% +2.3% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMRNAAMGNARGX
Held by institutions 80.2% 82.7% 46.1%
Institutions holding 784 3,159 504
Change in shares held, QoQ +3.4% +4.5% -2.0%
Institutions buying 402 1,451 264
Institutions selling 238 1,217 160
Buyers to sellers 1.69 1.19 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MRNAAMGNARGX
MRNA 1.00 0.25 0.17
AMGN 0.25 1.00 0.31
ARGX 0.17 0.31 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MRNA, AMGN and ARGX?

Amgen (AMGN) is the largest by market capitalisation: Moderna (MRNA) $85.53B, Amgen (AMGN) $243.49B, Argenx Se (ARGX) $54.42B.

Which stock is cheaper, MRNA, AMGN and ARGX?

Amgen (AMGN) trades on the lowest price-to-earnings ratio (Moderna (MRNA) -27.1x, Amgen (AMGN) 27.8x, Argenx Se (ARGX) 29.0x). On next year's consensus earnings, Amgen (AMGN) is cheapest (Amgen (AMGN) 20.5x, Argenx Se (ARGX) 28.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Moderna (MRNA) -27.6%, Amgen (AMGN) +9.1%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Moderna (MRNA) -141.4%, Amgen (AMGN) 23.0%, Argenx Se (ARGX) 32.3%). On return on invested capital, Amgen (AMGN) leads (Moderna (MRNA) -43.3%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Moderna (MRNA) +680.1%, Amgen (AMGN) +53.9%, Argenx Se (ARGX) +6.3%. Over five years, Argenx Se (ARGX) compounded fastest (Moderna (MRNA) -9.8%/yr, Amgen (AMGN) +16.7%/yr, Argenx Se (ARGX) +25.8%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Moderna (MRNA) 0.00%, Amgen (AMGN) 0.02%, Argenx Se (ARGX) 0.00%. Moderna (MRNA) and Argenx Se (ARGX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Moderna (MRNA) 130.8%, Amgen (AMGN) 29.6%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MRNA, AMGN and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.