MESO vs PGEN vs SLBT Stock Comparison

Mesoblast, Precigen and SL Science Holding Prices as of Oct 27, 2026 Peers: Industry group
MESO Mesoblast Ltd
$13.18 -12.8% 1M -21.1% 1Y
Market cap
$1.72B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
PGEN Precigen, Inc.
$6.15 -20.6% 1M +43.0% 1Y
Market cap
$2.21B
P/E
–
Revenue (TTM)
$85.72M
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
SLBT SL Science Holding Ltd
$1.19 -24.2% 1M -88.5% 1Y
Market cap
$2.71B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

4 decided of 12

Precigen leads on 2 of the 12 questions below (Precigen 2, SL Science Holding 1, Mesoblast 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMESOPGENSLBTLeader
Larger companyMarket capitalisation $1.72B $2.21B $2.71B SLBT
Cheaper on earningsLower P/E, profitable companies only -29.7x -6.6x — –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 36.2x — –
Faster revenue growthRevenue growth, trailing twelve months — +1,875.0% — –
More profitableNet margin, trailing twelve months — -392.8% — –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — -1.6x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -21.1% +43.0% -88.5% PGEN
Better 5-year returnAnnualised price return, 5 years +1.9%/yr +4.4%/yr — PGEN
Less volatileAnnualised volatility, 1 year 54.8% 77.9% 175.4% MESO
Higher overall scoreMean of the five percentile scores vs peers — 55/100 — –

Percentile Scorecard

MESOPGENSLBT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMESOPGENSLBT
Valuation 70 #189 of 625 59 #258 of 625 11 #555 of 625
Growth – 49 #310 of 602 –
Profitability – 59 #227 of 551 –
Financial Health 44 #365 of 656 27 #482 of 656 58 #279 of 656
Shareholder Returns – 83 #63 of 365 –
Overall – 55 –
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PGEN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • SLBT ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMESOPGENSLBTSPY
1 month -12.8%-20.6%-24.2% -0.2%
3 months -8.8%+11.2%-56.7% +3.9%
6 months -13.4%+53.0%-84.9% +8.2%
Year to date -26.9%+47.1%-88.7% +12.9%
1 year -21.1%+43.0%-88.5% +12.3%
3 years +463.2%+508.9%— +87.4%
3 years, per year +78.0%+82.7%— +23.3%
5 years +9.7%+24.0%— +67.9%
5 years, per year +1.9%+4.4%— +10.9%
10 years +56.2%-76.2%— +261.1%
10 years, per year +4.6%-13.4%— +13.7%

Risk

MeasureMESOPGENSLBTSPY
Volatility, 1Y 54.8%77.9%175.4% 12.7%
Downside volatility, 1Y 54.9%69.4%170.6% 12.7%
Beta vs S&P 500, 1Y 1.521.430.23 1.00
Return / volatility, 1Y -0.390.55-0.50 0.97
Max drawdown, 5Y -87.9%-87.8%-91.0% -25.4%
From 52-week high -37.1%-28.2%-90.7% -1.2%
52-week high $20.96$8.56$12.81 $779.14
52-week low $11.95$3.10$1.15 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMESOPGENSLBT
P/E now vs peer median -29.7xmedian 17.2x -6.5xmedian 17.2x —median 17.2x
P/S now vs peer median 14.2xmedian 9.0x 25.7xmedian 9.0x —median 9.0x
EV/EBITDA now vs peer median —median 16.3x -65.8xmedian 16.3x —median 16.3x
P/FCF now vs peer median -38.2xmedian 18.7x -19.1xmedian 18.7x -1,382xmedian 18.7x
P/B now vs peer median 3.0xmedian 2.2x 50.5xmedian 2.2x 372.2xmedian 2.2x
PEG now vs peer median —median 0.33 0.05median 0.33 —median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMESOPGENSLBT
Revenue – $85.72M –
Gross profit – $77.72M –
Operating income – -$39.50M –
Net income – -$157.71M –
Free cash flow – -$115.22M –
R&D – $32.29M –
EPS (diluted) – $-0.81 –
Cash & equivalents $102.91M $16.33M $8.31M
Total debt $119.24M $93.88M –
Shares (diluted) 129.49M 413.69M –
Enterprise value $1.29B $1.90B $2.69B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMESOPGENSLBT
P/E -29.7x -6.5x –
P/FCF -38.2x -19.1x -1,382x
P/Operating cash flow – -19.3x –
P/S 14.2x 25.7x –
P/B 3.0x 50.5x 372.2x
P/Tangible book 3.0x 53.7x 372.2x
EV/EBITDA – -65.8x –
EV/EBIT – -57.2x –
EV/Revenue – 26.3x –
EV/FCF – -19.6x –
EV/Operating cash flow – -19.8x –
PEG (3Y EPS CAGR) – 0.05 –

Growth

14 metrics
MetricMESOPGENSLBT
Revenue growth (1Y) – 1,875% –
Revenue CAGR (3Y) – 57.1% –
Gross profit growth (1Y) – 259,173% –
Gross profit CAGR (3Y) – 69.2% –
Operating income growth (1Y) – 62.1% –
Operating income CAGR (3Y) – 18.9% –
Net income growth (1Y) – -26.7% –
Net income CAGR (3Y) – -108.9% –
EPS growth (1Y) – -93.8% –
EPS CAGR (3Y) – -123.2% –
Operating cash flow growth (1Y) – -72.3% –
Operating cash flow CAGR (3Y) – -15.9% –
Free cash flow growth (1Y) – -65.1% –
Free cash flow CAGR (3Y) – -15.3% –

Profitability

14 metrics
MetricMESOPGENSLBT
Gross margin – 90.7% –
EBITDA margin – -40.0% –
Operating margin – -46.1% –
Pretax margin – -184.0% –
Net margin – -392.8% –
FCF margin – -134.4% –
Operating cash flow margin – -133.2% –
Return on equity – -494.3% –
Return on assets – -102.1% –
Return on invested capital – – –
Return on capital employed – -31.6% –
Asset turnover – 0.6x –
Cash conversion (OCF / net income) – 0.7x –
Stock comp / revenue – 15.3% –

Financial Health

11 metrics
MetricMESOPGENSLBT
Debt / assets 15.4% 55.1% –
Debt / equity 0.2x 2.2x –
Net debt / EBITDA – -1.6x –
Debt / FCF – -0.8x –
Liabilities / assets 26.5% 74.4% 21.8%
Equity / assets 73.5% 25.6% 78.2%
Interest coverage – -4.1x –
Current ratio 2.4x 4.6x 4.4x
Quick ratio 2.0x 3.8x 4.3x
Cash ratio 1.3x 1.3x 4.3x
Altman Z-score – -8.25 –

Shareholder Returns

7 metrics
MetricMESOPGENSLBT
Dividend yield – – –
Net buyback yield – -0.1% –
Shareholder yield – -0.1% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMESOPGENSLBT
Forward P/E – 36.2xFY2026 –
EPS, next fiscal year $-0.15FY2027 $0.17FY2026 –
EPS growth, the year after – +288.2% –
Revenue, next fiscal year $188.99MFY2027 $249.17MFY2026 –
Revenue growth, next FY +57.2%FY2027 +2,474.1%FY2026 –
Revenue growth, the year after +110.3% +82.3% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMESOPGENSLBT
Held by institutions 3.0% 39.2% –
Institutions holding 73 210 –
Change in shares held, QoQ +17.7% +4.9% –
Institutions buying 34 123 –
Institutions selling 20 46 –
Buyers to sellers 1.70 2.67 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MESOPGENSLBT
MESO 1.00 0.20 0.00
PGEN 0.20 1.00 0.00
SLBT 0.00 0.00 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, MESO, PGEN and SLBT?

SL Science Holding (SLBT) is the largest by market capitalisation: Mesoblast (MESO) $1.72B, Precigen (PGEN) $2.21B, SL Science Holding (SLBT) $2.71B.

Which stock has performed better?

Over the past year Precigen (PGEN) returned the most: Mesoblast (MESO) -21.1%, Precigen (PGEN) +43.0%, SL Science Holding (SLBT) -88.5%. Over five years, Precigen (PGEN) compounded fastest (Mesoblast (MESO) +1.9%/yr, Precigen (PGEN) +4.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Mesoblast (MESO) 54.8%, Precigen (PGEN) 77.9%, SL Science Holding (SLBT) 175.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MESO, PGEN and SLBT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Precigen (PGEN) leads on 2. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.