MESO vs IMMX vs LEGN Stock Comparison

Mesoblast, Immix Biopharma and Legend Biotech Prices as of Oct 28, 2026 Peers: Industry group
MESO Mesoblast Ltd
$13.39 -7.7% 1M -20.0% 1Y
Market cap
$1.73B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
IMMX Immix Biopharma, Inc.
$8.12 -29.2% 1M +108.2% 1Y
Market cap
$580.87M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
1 win
LEGN Legend Biotech Corp
$22.53 +21.0% 1M -30.8% 1Y
Market cap
$4.15B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

5 decided of 12

Legend Biotech leads on 2 of the 12 questions below (Legend Biotech 2, Mesoblast 2, Immix Biopharma 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMESOIMMXLEGNLeader
Larger companyMarket capitalisation $1.73B $580.87M $4.15B LEGN
Cheaper on earningsLower P/E, profitable companies only -30.2x -13.0x -45.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — — +59.5% –
More profitableNet margin, trailing twelve months — — -7.2% –
Better return on capitalReturn on invested capital — — -4.2% –
Less leveragedLower net debt / EBITDA — — 28.0x –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months -20.0% +108.2% -30.8% IMMX
Better 5-year returnAnnualised price return, 5 years +2.0%/yr — -15.6%/yr MESO
Less volatileAnnualised volatility, 1 year 54.8% 82.8% 72.3% MESO
Higher overall scoreMean of the five percentile scores vs peers — 53/100 73/100 LEGN

Percentile Scorecard

MESOIMMXLEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMESOIMMXLEGN
Valuation 71 #185 of 625 73 #170 of 625 89 #72 of 625
Growth – 6 #569 of 602 96 #23 of 602
Profitability – 79 #119 of 549 80 #109 of 549
Financial Health 44 #364 of 654 97 #18 of 654 54 #299 of 654
Shareholder Returns – 9 #334 of 367 44 #206 of 367
Overall – 53 73
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IMMX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMESOIMMXLEGNSPY
1 month -7.7%-29.2%+21.0% +0.9%
3 months -5.2%-0.6%+19.5% +5.9%
6 months -13.9%-5.9%-1.1% +8.5%
Year to date -25.8%+55.3%+3.6% +13.3%
1 year -20.0%+108.2%-30.8% +12.4%
3 years +472.2%+139.5%-64.6% +88.1%
3 years, per year +78.9%+33.8%-29.3% +23.5%
5 years +10.7%—-57.1% +68.2%
5 years, per year +2.0%—-15.6% +11.0%
10 years +55.0%—— +263.4%
10 years, per year +4.5%—— +13.8%

Risk

MeasureMESOIMMXLEGNSPY
Volatility, 1Y 54.8%82.8%72.3% 12.7%
Downside volatility, 1Y 54.9%76.3%62.7% 12.7%
Beta vs S&P 500, 1Y 1.531.570.44 1.00
Return / volatility, 1Y -0.361.31-0.43 0.98
Max drawdown, 5Y -87.9%-88.9%-78.2% -25.4%
From 52-week high -36.1%-43.9%-37.9% -0.9%
52-week high $20.96$14.47$36.28 $779.14
52-week low $11.95$3.03$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMESOIMMXLEGN
P/E now vs peer median -30.2xmedian 17.4x -13.0xmedian 17.4x -45.3xmedian 17.4x
P/S now vs peer median 14.4xmedian 9.1x —median 9.1x 3.3xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x -8.4xmedian 17.1x -197.3xmedian 17.1x
P/FCF now vs peer median -38.8xmedian 19.0x -14.9xmedian 19.0x -64.3xmedian 19.0x
P/B now vs peer median 3.1xmedian 2.2x 2.5xmedian 2.2x 3.4xmedian 2.2x
PEG now vs peer median —median 0.34 -2.10median 0.34 -0.96median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMESOIMMXLEGN
Revenue – – $1.27B
Gross profit – – $727.10M
Operating income – -$41.82M -$55.25M
Net income – -$39.88M -$80.39M
Free cash flow – -$39.09M -$64.60M
R&D – $21.62M $396.15M
EPS (diluted) – $-0.63 $-0.50
Cash & equivalents $102.91M $225.49M $672.90M
Total debt $119.24M – $1.06B
Shares (diluted) 129.49M 63.77M 184.32M
Enterprise value $1.30B $348.77M $1.65B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMESOIMMXLEGN
P/E -30.2x -13.0x -45.3x
P/FCF -38.8x -14.9x -64.3x
P/Operating cash flow – -15.1x -46.5x
P/S 14.4x – 3.3x
P/B 3.1x 2.5x 3.4x
P/Tangible book 3.1x 2.5x 3.4x
EV/EBITDA – -8.4x -197.3x
EV/EBIT – -8.3x -65.8x
EV/Revenue – – 2.9x
EV/FCF – -8.9x -56.3x
EV/Operating cash flow – -9.1x -40.7x
PEG (3Y EPS CAGR) – -2.10 -0.96

Growth

14 metrics
MetricMESOIMMXLEGN
Revenue growth (1Y) – – 59.5%
Revenue CAGR (3Y) – – 97.6%
Gross profit growth (1Y) – – 42.4%
Gross profit CAGR (3Y) – – 147.5%
Operating income growth (1Y) – -75.8% 75.3%
Operating income CAGR (3Y) – -53.5% 49.1%
Net income growth (1Y) – -72.4% 75.3%
Net income CAGR (3Y) – -51.7% 46.7%
EPS growth (1Y) – 18.9% 72.0%
EPS CAGR (3Y) – 6.2% 47.0%
Operating cash flow growth (1Y) – -207.8% 67.5%
Operating cash flow CAGR (3Y) – -51.9% 37.1%
Free cash flow growth (1Y) – -190.0% 77.8%
Free cash flow CAGR (3Y) – -52.7% 44.5%

Profitability

14 metrics
MetricMESOIMMXLEGN
Gross margin – – 57.2%
EBITDA margin – – -1.5%
Operating margin – – -4.3%
Pretax margin – – -4.4%
Net margin – – -7.2%
FCF margin – – -5.1%
Operating cash flow margin – – -7.0%
Return on equity – -25.5% -8.3%
Return on assets – -23.8% -5.5%
Return on invested capital – – -4.2%
Return on capital employed – -26.4% -4.3%
Asset turnover – – 0.8x
Cash conversion (OCF / net income) – 1.0x 1.1x
Stock comp / revenue – – 5.2%

Financial Health

11 metrics
MetricMESOIMMXLEGN
Debt / assets 15.4% – 8.9%
Debt / equity 0.2x – 0.1x
Net debt / EBITDA – – 28.0x
Debt / FCF – – -2.4x
Liabilities / assets 26.5% 4.3% 29.8%
Equity / assets 73.5% 95.7% 70.2%
Interest coverage – – -4.8x
Current ratio 2.4x 25.1x 3.0x
Quick ratio 2.0x 25.0x 1.7x
Cash ratio 1.3x 25.0x 1.7x
Altman Z-score – – 6.95

Shareholder Returns

7 metrics
MetricMESOIMMXLEGN
Dividend yield – – –
Net buyback yield – -42.8% -5.2%
Shareholder yield – -42.8% -5.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMESOIMMXLEGN
EPS, next fiscal year $-0.15FY2027 $-0.70FY2026 $-0.04FY2026
Revenue, next fiscal year $188.99MFY2027 $0.00FY2026 $1.37BFY2026
Revenue growth, next FY +57.2%FY2027 – +32.9%FY2026
Revenue growth, the year after +110.3% – +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMESOIMMXLEGN
Held by institutions 3.0% 78.6% 55.9%
Institutions holding 73 110 218
Change in shares held, QoQ +17.7% +107.6% +7.3%
Institutions buying 34 81 117
Institutions selling 20 13 78
Buyers to sellers 1.70 6.23 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MESOIMMXLEGN
MESO 1.00 0.23 0.14
IMMX 0.23 1.00 0.04
LEGN 0.14 0.04 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, MESO, IMMX and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: Mesoblast (MESO) $1.73B, Immix Biopharma (IMMX) $580.87M, Legend Biotech (LEGN) $4.15B.

Which stock has performed better?

Over the past year Immix Biopharma (IMMX) returned the most: Mesoblast (MESO) -20.0%, Immix Biopharma (IMMX) +108.2%, Legend Biotech (LEGN) -30.8%. Over five years, Mesoblast (MESO) compounded fastest (Mesoblast (MESO) +2.0%/yr, Legend Biotech (LEGN) -15.6%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Mesoblast (MESO) 54.8%, Immix Biopharma (IMMX) 82.8%, Legend Biotech (LEGN) 72.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MESO, IMMX and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 2. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.