MESO vs ALLO vs LEGN Stock Comparison

Mesoblast, Allogene Therapeutics and Legend Biotech Prices as of Oct 27, 2026 Peers: Industry group
MESO Mesoblast Ltd
$13.18 -12.8% 1M -21.1% 1Y
Market cap
$1.71B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins
LEGN Legend Biotech Corp
$21.56 +12.8% 1M -32.9% 1Y
Market cap
$3.97B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

6 decided of 12

Legend Biotech leads on 3 of the 12 questions below (Legend Biotech 3, Mesoblast 2, Allogene Therapeutics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionMESOALLOLEGNLeader
Larger companyMarket capitalisation $1.71B $424.77M $3.97B LEGN
Cheaper on earningsLower P/E, profitable companies only -29.7x -2.4x -43.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — — +59.5% –
More profitableNet margin, trailing twelve months — -3,566.7% -7.2% LEGN
Better return on capitalReturn on invested capital — — -4.2% –
Less leveragedLower net debt / EBITDA — — 28.0x –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months -21.1% 0.0% -32.9% ALLO
Better 5-year returnAnnualised price return, 5 years +1.9%/yr -41.0%/yr -15.9%/yr MESO
Less volatileAnnualised volatility, 1 year 54.8% 82.7% 72.2% MESO
Higher overall scoreMean of the five percentile scores vs peers — 55/100 72/100 LEGN

Percentile Scorecard

MESOALLOLEGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisMESOALLOLEGN
Valuation 70 #189 of 625 18 #512 of 625 89 #70 of 625
Growth – 91 #58 of 602 96 #23 of 602
Profitability – 24 #417 of 551 80 #112 of 551
Financial Health 44 #365 of 656 63 #244 of 656 54 #305 of 656
Shareholder Returns – 79 #76 of 365 43 #209 of 365
Overall – 55 72
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ALLO ranked among 672 companies in Pharmaceuticals and Biotechnology
  • LEGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodMESOALLOLEGNSPY
1 month -12.8%-25.5%+12.8% -0.2%
3 months -8.8%-25.9%+13.2% +3.9%
6 months -13.4%-43.8%-8.5% +8.2%
Year to date -26.9%-10.2%-0.8% +12.9%
1 year -21.1%0.0%-32.9% +12.3%
3 years +463.2%-51.4%-66.1% +87.4%
3 years, per year +78.0%-21.4%-30.3% +23.3%
5 years +9.7%-92.8%-57.9% +67.9%
5 years, per year +1.9%-41.0%-15.9% +10.9%
10 years +56.2%—— +261.1%
10 years, per year +4.6%—— +13.7%

Risk

MeasureMESOALLOLEGNSPY
Volatility, 1Y 54.8%82.7%72.2% 12.7%
Downside volatility, 1Y 54.9%82.1%62.7% 12.7%
Beta vs S&P 500, 1Y 1.521.830.43 1.00
Return / volatility, 1Y -0.390.00-0.46 0.97
Max drawdown, 5Y -87.9%-95.3%-78.2% -25.4%
From 52-week high -37.1%-59.8%-40.6% -1.2%
52-week high $20.96$3.06$36.28 $779.14
52-week low $11.95$1.05$16.65 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleMESOALLOLEGN
P/E now vs peer median -29.7xmedian 17.2x -2.4xmedian 17.2x -43.3xmedian 17.2x
P/S now vs peer median 14.2xmedian 9.0x 91.5xmedian 9.0x 3.1xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x -0.5xmedian 16.3x -187.6xmedian 16.3x
P/FCF now vs peer median -38.2xmedian 18.7x -3.7xmedian 18.7x -61.5xmedian 18.7x
P/B now vs peer median 3.0xmedian 2.2x 1.0xmedian 2.2x 3.2xmedian 2.2x
PEG now vs peer median —median 0.33 -0.06median 0.33 -0.92median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsMESOALLOLEGN
Revenue – $4.64M $1.27B
Gross profit – – $727.10M
Operating income – -$180.32M -$55.25M
Net income – -$165.49M -$80.39M
Free cash flow – -$115.53M -$64.60M
R&D – $122.52M $396.15M
EPS (diluted) – $-0.50 $-0.50
Cash & equivalents $102.91M $38.63M $672.90M
Total debt $119.24M – $1.06B
Shares (diluted) 129.49M 328.93M 184.32M
Enterprise value $1.27B -$677.12M $1.47B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricMESOALLOLEGN
P/E -29.7x -2.4x -43.3x
P/FCF -38.2x -3.7x -61.5x
P/Operating cash flow – -4.2x -44.5x
P/S 14.2x 91.5x 3.1x
P/B 3.0x 1.0x 3.2x
P/Tangible book 3.0x 1.0x 3.2x
EV/EBITDA – -0.5x -187.6x
EV/EBIT – -0.5x -62.6x
EV/Revenue – 19.9x 2.7x
EV/FCF – -0.8x -53.5x
EV/Operating cash flow – -0.9x -38.7x
PEG (3Y EPS CAGR) – -0.06 -0.92

Growth

14 metrics
MetricMESOALLOLEGN
Revenue growth (1Y) – – 59.5%
Revenue CAGR (3Y) – 253.5% 97.6%
Gross profit growth (1Y) – – 42.4%
Gross profit CAGR (3Y) – – 147.5%
Operating income growth (1Y) – 29.1% 75.3%
Operating income CAGR (3Y) – 20.5% 49.1%
Net income growth (1Y) – 30.1% 75.3%
Net income CAGR (3Y) – 22.9% 46.7%
EPS growth (1Y) – 53.5% 72.0%
EPS CAGR (3Y) – 41.1% 47.0%
Operating cash flow growth (1Y) – 40.8% 67.5%
Operating cash flow CAGR (3Y) – 24.6% 37.1%
Free cash flow growth (1Y) – 38.0% 77.8%
Free cash flow CAGR (3Y) – 23.0% 44.5%

Profitability

14 metrics
MetricMESOALLOLEGN
Gross margin – – 57.2%
EBITDA margin – -3,634% -1.5%
Operating margin – -3,886% -4.3%
Pretax margin – -3,574% -4.4%
Net margin – -3,567% -7.2%
FCF margin – -2,490% -5.1%
Operating cash flow margin – -2,203% -7.0%
Return on equity – -46.4% -8.3%
Return on assets – -35.1% -5.5%
Return on invested capital – – -4.2%
Return on capital employed – -40.9% -4.3%
Asset turnover – 0.0x 0.8x
Cash conversion (OCF / net income) – 0.6x 1.1x
Stock comp / revenue – 808.0% 5.2%

Financial Health

11 metrics
MetricMESOALLOLEGN
Debt / assets 15.4% – 8.9%
Debt / equity 0.2x – 0.1x
Net debt / EBITDA – – 28.0x
Debt / FCF – – -2.4x
Liabilities / assets 26.5% 20.7% 29.8%
Equity / assets 73.5% 79.3% 70.2%
Interest coverage – -138.7x -4.8x
Current ratio 2.4x 10.7x 3.0x
Quick ratio 2.0x 10.5x 1.7x
Cash ratio 1.3x 10.5x 1.7x
Altman Z-score – -3.50 6.74

Shareholder Returns

7 metrics
MetricMESOALLOLEGN
Dividend yield – – –
Net buyback yield – -0.2% -5.4%
Shareholder yield – -0.2% -5.4%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusMESOALLOLEGN
EPS, next fiscal year $-0.15FY2027 $-0.63FY2026 $-0.04FY2026
Revenue, next fiscal year $188.99MFY2027 $4.07MFY2026 $1.37BFY2026
Revenue growth, next FY +57.2%FY2027 – +32.9%FY2026
Revenue growth, the year after +110.3% +207.8% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersMESOALLOLEGN
Held by institutions 3.0% 90.5% 55.9%
Institutions holding 73 209 218
Change in shares held, QoQ +17.7% +69.8% +7.3%
Institutions buying 34 133 117
Institutions selling 20 48 78
Buyers to sellers 1.70 2.77 1.50

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

MESOALLOLEGN
MESO 1.00 0.19 0.14
ALLO 0.19 1.00 0.08
LEGN 0.14 0.08 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, MESO, ALLO and LEGN?

Legend Biotech (LEGN) is the largest by market capitalisation: Mesoblast (MESO) $1.71B, Allogene Therapeutics (ALLO) $424.77M, Legend Biotech (LEGN) $3.97B.

Which company is more profitable?

Legend Biotech (LEGN) has the highest net margin (Allogene Therapeutics (ALLO) -3,566.7%, Legend Biotech (LEGN) -7.2%).

Which stock has performed better?

Over the past year Allogene Therapeutics (ALLO) returned the most: Mesoblast (MESO) -21.1%, Allogene Therapeutics (ALLO) 0.0%, Legend Biotech (LEGN) -32.9%. Over five years, Mesoblast (MESO) compounded fastest (Mesoblast (MESO) +1.9%/yr, Allogene Therapeutics (ALLO) -41.0%/yr, Legend Biotech (LEGN) -15.9%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Mesoblast (MESO) 54.8%, Allogene Therapeutics (ALLO) 82.7%, Legend Biotech (LEGN) 72.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, MESO, ALLO and LEGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.