LEGN vs BEAM vs SRPT Stock Comparison

Legend Biotech, Beam Therapeutics and Sarepta Therapeutics Prices as of Oct 26, 2026 Peers: Industry group
LEGN Legend Biotech Corp
$20.39 +6.7% 1M -36.0% 1Y
Market cap
$3.99B
P/E
–
Revenue (TTM)
$1.27B
Div. yield
–
Gene and Cell Therapy Healthcare
4 wins
BEAM Beam Therapeutics Inc.
$23.79 -2.0% 1M -14.9% 1Y
Market cap
$2.60B
P/E
–
Revenue (TTM)
$156.04M
Div. yield
–
Gene and Cell Therapy Healthcare
3 wins

Head to Head

9 decided of 12

Legend Biotech leads on 4 of the 12 questions below (Legend Biotech 4, Beam Therapeutics 3, Sarepta Therapeutics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionLEGNBEAMSRPTLeader
Larger companyMarket capitalisation $3.99B $2.60B $1.99B LEGN
Cheaper on earningsLower P/E, profitable companies only -43.5x -30.4x -17.0x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.2x –
Faster revenue growthRevenue growth, trailing twelve months +59.5% +158.9% -20.4% BEAM
More profitableNet margin, trailing twelve months -7.2% -54.7% -5.9% SRPT
Better return on capitalReturn on invested capital -4.2% — -6.1% LEGN
Less leveragedLower net debt / EBITDA 28.0x 3.0x -0.6x SRPT
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -36.0% -14.9% -21.2% BEAM
Better 5-year returnAnnualised price return, 5 years -17.0%/yr -23.7%/yr -25.3%/yr LEGN
Less volatileAnnualised volatility, 1 year 72.1% 69.2% 81.2% BEAM
Higher overall scoreMean of the five percentile scores vs peers 72/100 69/100 67/100 LEGN

Percentile Scorecard

LEGNBEAMSRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisLEGNBEAMSRPT
Valuation 89 #71 of 626 55 #284 of 626 97 #23 of 626
Growth 97 #21 of 604 77 #138 of 604 63 #222 of 604
Profitability 80 #114 of 555 64 #200 of 555 79 #116 of 555
Financial Health 54 #306 of 658 81 #127 of 658 34 #438 of 658
Shareholder Returns 43 #212 of 368 66 #125 of 368 61 #146 of 368
Overall 72 69 67
  • LEGN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • BEAM ranked among 673 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodLEGNBEAMSRPTSPY
1 month +6.7%-2.0%-3.7% -0.8%
3 months +5.8%-5.1%+13.2% +3.5%
6 months -13.8%-18.4%-14.3% +7.0%
Year to date -6.2%-14.2%-16.4% +12.2%
1 year -36.0%-14.9%-21.2% +13.0%
3 years -68.0%+27.8%-83.2% +86.3%
3 years, per year -31.6%+8.5%-44.8% +23.1%
5 years -60.6%-74.1%-76.7% +68.6%
5 years, per year -17.0%-23.7%-25.3% +11.0%
10 years ——-59.6% +258.0%
10 years, per year ——-8.7% +13.6%

Risk

MeasureLEGNBEAMSRPTSPY
Volatility, 1Y 72.1%69.2%81.2% 12.7%
Downside volatility, 1Y 62.7%63.8%85.9% 12.7%
Beta vs S&P 500, 1Y 0.412.052.07 1.00
Return / volatility, 1Y -0.50-0.22-0.26 1.02
Max drawdown, 5Y -78.2%-85.3%-92.7% -25.4%
From 52-week high -43.8%-37.3%-26.5% -1.8%
52-week high $36.28$37.92$24.45 $779.14
52-week low $16.65$20.60$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleLEGNBEAMSRPT
P/E now vs peer median -41.0xmedian 17.1x -29.1xmedian 17.1x -16.2xmedian 17.1x
P/S now vs peer median 3.0xmedian 8.8x 15.7xmedian 8.8x 1.0xmedian 8.8x
EV/EBITDA now vs peer median -175.9xmedian 17.1x -3.9xmedian 17.1x -19.9xmedian 17.1x
P/FCF now vs peer median -58.2xmedian 18.0x -6.6xmedian 18.0x 23.2xmedian 18.0x
P/B now vs peer median 3.1xmedian 2.1x 2.3xmedian 2.1x 1.2xmedian 2.1x
PEG now vs peer median -0.87median 0.31 -0.69median 0.31 -0.31median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsLEGNBEAMSRPT
Revenue $1.27B $156.04M $1.97B
Gross profit $727.10M – $1.17B
Operating income -$55.25M -$378.02M -$143.25M
Net income -$80.39M -$86.52M -$136.73M
Free cash flow -$64.60M -$372.77M $81.85M
R&D $396.15M $408.66M $789.44M
EPS (diluted) $-0.50 $-0.82 $-1.11
Cash & equivalents $672.90M $219.83M $571.15M
Total debt $1.06B $100.26M $847.62M
Shares (diluted) 184.32M 104.33M 105.43M
Enterprise value $1.48B -$2.08B -$1.24B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricLEGNBEAMSRPT
P/E -41.0x -29.1x -16.2x
P/FCF -58.2x -6.6x 23.2x
P/Operating cash flow -42.0x -6.8x 17.1x
P/S 3.0x 15.7x 1.0x
P/B 3.1x 2.3x 1.2x
P/Tangible book 3.1x 2.3x 1.3x
EV/EBITDA -175.9x -3.9x -19.9x
EV/EBIT -58.7x -3.7x -13.7x
EV/Revenue 2.6x 9.0x 1.0x
EV/FCF -50.2x -3.8x 23.9x
EV/Operating cash flow -36.3x -3.9x 17.6x
PEG (3Y EPS CAGR) -0.87 -0.69 -0.31

Growth

14 metrics
MetricLEGNBEAMSRPT
Revenue growth (1Y) 59.5% 158.9% -20.4%
Revenue CAGR (3Y) 97.6% 24.9% 25.3%
Gross profit growth (1Y) 42.4% – -40.7%
Gross profit CAGR (3Y) 147.5% – 10.6%
Operating income growth (1Y) 75.3% 15.2% -15,270%
Operating income CAGR (3Y) 49.1% 0.3% 34.5%
Net income growth (1Y) 75.3% 78.2% -135.9%
Net income CAGR (3Y) 46.7% 35.8% 46.8%
EPS growth (1Y) 72.0% 79.0% -215.7%
EPS CAGR (3Y) 47.0% 42.4% 52.3%
Operating cash flow growth (1Y) 67.5% -4.2% 136.9%
Operating cash flow CAGR (3Y) 37.1% -2.0% 30.6%
Free cash flow growth (1Y) 77.8% -4.8% 118.1%
Free cash flow CAGR (3Y) 44.5% 0.7% 29.1%

Profitability

14 metrics
MetricLEGNBEAMSRPT
Gross margin 57.2% – 59.1%
EBITDA margin -1.5% -228.0% -5.0%
Operating margin -4.3% -242.3% -7.3%
Pretax margin -4.4% -54.4% -6.6%
Net margin -7.2% -54.7% -5.9%
FCF margin -5.1% -238.9% 4.1%
Operating cash flow margin -7.0% -230.3% 5.6%
Return on equity -8.3% -7.6% -9.0%
Return on assets -5.5% -5.9% -4.3%
Return on invested capital -4.2% – -6.1%
Return on capital employed -4.3% -27.9% -5.3%
Asset turnover 0.8x 0.1x 0.6x
Cash conversion (OCF / net income) 1.1x 4.2x -0.8x
Stock comp / revenue 5.2% 52.2% 6.3%

Financial Health

11 metrics
MetricLEGNBEAMSRPT
Debt / assets 8.9% 7.2% 26.6%
Debt / equity 0.1x 0.1x 0.6x
Net debt / EBITDA 28.0x 3.0x -0.6x
Debt / FCF -2.4x -0.3x 10.4x
Liabilities / assets 29.8% 23.0% 52.1%
Equity / assets 70.2% 77.0% 47.9%
Interest coverage -4.8x – –
Current ratio 3.0x 14.6x 4.4x
Quick ratio 1.7x 14.3x 2.4x
Cash ratio 1.7x 14.3x 1.6x
Altman Z-score 6.50 2.87 -0.19

Shareholder Returns

7 metrics
MetricLEGNBEAMSRPT
Dividend yield – – –
Net buyback yield -5.7% -0.6% -1.1%
Shareholder yield -5.7% -0.6% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusLEGNBEAMSRPT
Forward P/E – – 6.2xFY2026
EPS, next fiscal year $-0.04FY2026 $-4.22FY2026 $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $1.37BFY2026 $49.46MFY2026 $1.76BFY2026
Revenue growth, next FY +32.9%FY2026 -64.6%FY2026 -20.1%FY2026
Revenue growth, the year after +35.9% +23.6% -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersLEGNBEAMSRPT
Held by institutions 55.9% 100.0% 100.0%
Institutions holding 218 277 324
Change in shares held, QoQ +7.3% +1.0% +4.5%
Institutions buying 117 154 148
Institutions selling 78 75 115
Buyers to sellers 1.50 2.05 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

LEGNBEAMSRPT
LEGN 1.00 0.08 0.09
BEAM 0.08 1.00 0.36
SRPT 0.09 0.36 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, LEGN, BEAM and SRPT?

Legend Biotech (LEGN) is the largest by market capitalisation: Legend Biotech (LEGN) $3.99B, Beam Therapeutics (BEAM) $2.60B, Sarepta Therapeutics (SRPT) $1.99B.

Which company is growing faster?

Beam Therapeutics (BEAM) grew revenue fastest over the trailing twelve months: Legend Biotech (LEGN) +59.5%, Beam Therapeutics (BEAM) +158.9%, Sarepta Therapeutics (SRPT) -20.4%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Legend Biotech (LEGN) -7.2%, Beam Therapeutics (BEAM) -54.7%, Sarepta Therapeutics (SRPT) -5.9%). On return on invested capital, Legend Biotech (LEGN) leads (Legend Biotech (LEGN) -4.2%, Sarepta Therapeutics (SRPT) -6.1%).

Which stock has performed better?

Over the past year Beam Therapeutics (BEAM) returned the most: Legend Biotech (LEGN) -36.0%, Beam Therapeutics (BEAM) -14.9%, Sarepta Therapeutics (SRPT) -21.2%. Over five years, Legend Biotech (LEGN) compounded fastest (Legend Biotech (LEGN) -17.0%/yr, Beam Therapeutics (BEAM) -23.7%/yr, Sarepta Therapeutics (SRPT) -25.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Beam Therapeutics (BEAM) has been the steadiest (Legend Biotech (LEGN) 72.1%, Beam Therapeutics (BEAM) 69.2%, Sarepta Therapeutics (SRPT) 81.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, LEGN, BEAM and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Legend Biotech (LEGN) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.