IMTX vs IOVA vs SRPT Stock Comparison

Immatics, Iovance Biotherapeutics and Sarepta Therapeutics Prices as of Oct 26, 2026 Peers: Industry group
IMTX Immatics N.V.
$7.15 -14.6% 1M -29.8% 1Y
Market cap
$889.47M
P/E
–
Revenue (TTM)
$48.61M
Div. yield
–
Gene and Cell Therapy Healthcare
1 win

Head to Head

7 decided of 12

Iovance Biotherapeutics leads on 4 of the 12 questions below (Iovance Biotherapeutics 4, Sarepta Therapeutics 2, Immatics 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIMTXIOVASRPTLeader
Larger companyMarket capitalisation $889.47M $6.55B $1.95B IOVA
Cheaper on earningsLower P/E, profitable companies only -3.7x -22.6x -16.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 6.2x –
Faster revenue growthRevenue growth, trailing twelve months -65.4% +34.5% -20.4% IOVA
More profitableNet margin, trailing twelve months -495.7% -89.1% -5.9% SRPT
Better return on capitalReturn on invested capital — — -6.1% –
Less leveragedLower net debt / EBITDA — — -0.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -29.8% +512.4% -21.2% IOVA
Better 5-year returnAnnualised price return, 5 years -11.9%/yr -11.6%/yr -25.3%/yr IOVA
Less volatileAnnualised volatility, 1 year 57.7% 99.2% 81.2% IMTX
Higher overall scoreMean of the five percentile scores vs peers 36/100 63/100 67/100 SRPT

Percentile Scorecard

IMTXIOVASRPT

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIMTXIOVASRPT
Valuation 28 #449 of 626 66 #211 of 626 97 #23 of 626
Growth 4 #581 of 604 81 #114 of 604 63 #222 of 604
Profitability 45 #307 of 555 62 #210 of 555 79 #116 of 555
Financial Health 74 #169 of 658 63 #242 of 658 34 #438 of 658
Shareholder Returns 26 #271 of 368 44 #208 of 368 61 #146 of 368
Overall 36 63 67
  • IMTX ranked among 673 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 673 companies in Pharmaceuticals and Biotechnology
  • SRPT ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIMTXIOVASRPTSPY
1 month -14.6%+25.3%-3.7% -0.8%
3 months -17.1%+181.2%+13.2% +3.5%
6 months -37.0%+301.7%-14.3% +7.0%
Year to date -31.9%+404.8%-16.4% +12.2%
1 year -29.8%+512.4%-21.2% +13.0%
3 years -5.3%+293.7%-83.2% +86.3%
3 years, per year -1.8%+58.0%-44.8% +23.1%
5 years -46.8%-45.9%-76.7% +68.6%
5 years, per year -11.9%-11.6%-25.3% +11.0%
10 years —+125.9%-59.6% +258.0%
10 years, per year —+8.5%-8.7% +13.6%

Risk

MeasureIMTXIOVASRPTSPY
Volatility, 1Y 57.7%99.2%81.2% 12.7%
Downside volatility, 1Y 59.2%71.2%85.9% 12.7%
Beta vs S&P 500, 1Y 1.351.262.07 1.00
Return / volatility, 1Y -0.525.16-0.26 1.02
Max drawdown, 5Y -75.7%-93.5%-92.7% -25.4%
From 52-week high -39.8%-7.3%-26.5% -1.8%
52-week high $11.87$14.86$24.45 $779.14
52-week low $6.73$1.81$14.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIMTXIOVASRPT
P/E now vs peer median -3.6xmedian 17.1x -21.4xmedian 17.1x -16.2xmedian 17.1x
P/S now vs peer median 19.7xmedian 8.8x 19.2xmedian 8.8x 1.0xmedian 8.8x
EV/EBITDA now vs peer median -2.0xmedian 17.1x -22.5xmedian 17.1x -19.9xmedian 17.1x
P/FCF now vs peer median -3.9xmedian 18.0x -21.1xmedian 18.0x 23.2xmedian 18.0x
P/B now vs peer median 2.1xmedian 2.1x 8.5xmedian 2.1x 1.2xmedian 2.1x
PEG now vs peer median 0.15median 0.31 -0.72median 0.31 -0.31median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIMTXIOVASRPT
Revenue $48.61M $324.97M $1.97B
Gross profit – $157.29M $1.17B
Operating income -$264.59M -$301.31M -$143.25M
Net income -$240.97M -$289.51M -$136.73M
Free cash flow -$244.28M -$296.40M $81.85M
R&D $254.77M $267.72M $789.44M
EPS (diluted) $-1.97 $-0.64 $-1.11
Cash & equivalents $265.52M $110.80M $571.15M
Total debt – – $847.62M
Shares (diluted) 122.35M 450.19M 105.43M
Enterprise value -$1.14B $5.35B -$1.28B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIMTXIOVASRPT
P/E -3.6x -21.4x -16.2x
P/FCF -3.9x -21.1x 23.2x
P/Operating cash flow -4.0x -23.6x 17.1x
P/S 19.7x 19.2x 1.0x
P/B 2.1x 8.5x 1.2x
P/Tangible book 2.1x 13.2x 1.3x
EV/EBITDA -2.0x -22.5x -19.9x
EV/EBIT -1.9x -19.7x -13.7x
EV/Revenue 10.5x 18.3x 1.0x
EV/FCF -2.1x -20.1x 23.9x
EV/Operating cash flow -2.1x -22.5x 17.6x
PEG (3Y EPS CAGR) 0.15 -0.72 -0.31

Growth

14 metrics
MetricIMTXIOVASRPT
Revenue growth (1Y) -65.4% 34.5% -20.4%
Revenue CAGR (3Y) -47.1% 1,009% 25.3%
Gross profit growth (1Y) – 95.1% -40.7%
Gross profit CAGR (3Y) – – 10.6%
Operating income growth (1Y) -176.1% 26.6% -15,270%
Operating income CAGR (3Y) -58.8% 11.1% 34.5%
Net income growth (1Y) -187.4% 25.8% -135.9%
Net income CAGR (3Y) -37.5% 11.6% 46.8%
EPS growth (1Y) -180.7% 44.8% -215.7%
EPS CAGR (3Y) -23.8% 29.9% 52.3%
Operating cash flow growth (1Y) -33.6% 12.9% 136.9%
Operating cash flow CAGR (3Y) -39.1% 7.6% 30.6%
Free cash flow growth (1Y) -29.2% 8.4% 118.1%
Free cash flow CAGR (3Y) -30.7% 5.8% 29.1%

Profitability

14 metrics
MetricIMTXIOVASRPT
Gross margin – 48.4% 59.1%
EBITDA margin -515.5% -81.4% -5.0%
Operating margin -544.3% -92.7% -7.3%
Pretax margin -496.3% -90.4% -6.6%
Net margin -495.7% -89.1% -5.9%
FCF margin -502.6% -91.2% 4.1%
Operating cash flow margin -493.8% -81.3% 5.6%
Return on equity -49.2% -39.7% -9.0%
Return on assets -40.9% -31.4% -4.3%
Return on invested capital – – -6.1%
Return on capital employed -50.5% -37.0% -5.3%
Asset turnover 0.1x 0.4x 0.6x
Cash conversion (OCF / net income) 1.0x 0.9x -0.8x
Stock comp / revenue 42.1% 14.4% 6.3%

Financial Health

11 metrics
MetricIMTXIOVASRPT
Debt / assets – – 26.6%
Debt / equity – – 0.6x
Net debt / EBITDA – – -0.6x
Debt / FCF – – 10.4x
Liabilities / assets 17.7% 19.6% 52.1%
Equity / assets 82.3% 80.4% 47.9%
Interest coverage -3.2x – –
Current ratio 7.5x 4.3x 4.4x
Quick ratio 7.0x 3.7x 2.4x
Cash ratio 6.9x 2.8x 1.6x
Altman Z-score 2.67 16.17 -0.19

Shareholder Returns

7 metrics
MetricIMTXIOVASRPT
Dividend yield – – –
Net buyback yield -15.8% -4.7% -1.1%
Shareholder yield -15.8% -4.7% -1.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIMTXIOVASRPT
Forward P/E – – 6.2xFY2026
EPS, next fiscal year $-2.10FY2026 $-0.47FY2026 $2.88FY2026
EPS growth, the year after – – -88.5%
Revenue, next fiscal year $40.64MFY2026 $434.71MFY2026 $1.76BFY2026
Revenue growth, next FY -28.4%FY2026 +65.0%FY2026 -20.1%FY2026
Revenue growth, the year after -11.9% +33.0% -21.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIMTXIOVASRPT
Held by institutions 81.6% 63.3% 100.0%
Institutions holding 83 292 324
Change in shares held, QoQ -7.8% +6.5% +4.5%
Institutions buying 37 174 148
Institutions selling 33 66 115
Buyers to sellers 1.12 2.64 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IMTXIOVASRPT
IMTX 1.00 0.27 0.37
IOVA 0.27 1.00 0.28
SRPT 0.37 0.28 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, IMTX, IOVA and SRPT?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Immatics (IMTX) $889.47M, Iovance Biotherapeutics (IOVA) $6.55B, Sarepta Therapeutics (SRPT) $1.95B.

Which company is growing faster?

Iovance Biotherapeutics (IOVA) grew revenue fastest over the trailing twelve months: Immatics (IMTX) -65.4%, Iovance Biotherapeutics (IOVA) +34.5%, Sarepta Therapeutics (SRPT) -20.4%.

Which company is more profitable?

Sarepta Therapeutics (SRPT) has the highest net margin (Immatics (IMTX) -495.7%, Iovance Biotherapeutics (IOVA) -89.1%, Sarepta Therapeutics (SRPT) -5.9%).

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Immatics (IMTX) -29.8%, Iovance Biotherapeutics (IOVA) +512.4%, Sarepta Therapeutics (SRPT) -21.2%. Over five years, Iovance Biotherapeutics (IOVA) compounded fastest (Immatics (IMTX) -11.9%/yr, Iovance Biotherapeutics (IOVA) -11.6%/yr, Sarepta Therapeutics (SRPT) -25.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Immatics (IMTX) has been the steadiest (Immatics (IMTX) 57.7%, Iovance Biotherapeutics (IOVA) 99.2%, Sarepta Therapeutics (SRPT) 81.2%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IMTX, IOVA and SRPT?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.