IMMX vs IOVA vs MESO Stock Comparison

Immix Biopharma, Iovance Biotherapeutics and Mesoblast Prices as of Oct 28, 2026 Peers: Industry group
IMMX Immix Biopharma, Inc.
$8.12 -29.2% 1M +108.2% 1Y
Market cap
$508.11M
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
MESO Mesoblast Ltd
$13.39 -7.7% 1M -20.0% 1Y
Market cap
$2.02B
P/E
–
Revenue (TTM)
—
Div. yield
–
Gene and Cell Therapy Healthcare
2 wins

Head to Head

5 decided of 12

Iovance Biotherapeutics leads on 3 of the 12 questions below (Iovance Biotherapeutics 3, Mesoblast 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIMMXIOVAMESOLeader
Larger companyMarket capitalisation $508.11M $4.32B $2.02B IOVA
Cheaper on earningsLower P/E, profitable companies only -12.7x -14.9x -30.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — — –
Faster revenue growthRevenue growth, trailing twelve months — +34.5% — –
More profitableNet margin, trailing twelve months — -89.1% — –
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +108.2% +576.3% -20.0% IOVA
Better 5-year returnAnnualised price return, 5 years — -9.4%/yr +2.0%/yr MESO
Less volatileAnnualised volatility, 1 year 82.8% 99.0% 54.8% MESO
Higher overall scoreMean of the five percentile scores vs peers 53/100 64/100 — IOVA

Percentile Scorecard

IMMXIOVAMESO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIMMXIOVAMESO
Valuation 73 #170 of 625 67 #208 of 625 71 #185 of 625
Growth 6 #569 of 602 81 #113 of 602 –
Profitability 79 #119 of 549 63 #206 of 549 –
Financial Health 97 #18 of 654 64 #235 of 654 44 #364 of 654
Shareholder Returns 9 #334 of 367 45 #204 of 367 –
Overall 53 64 –
  • IMMX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • IOVA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MESO ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIMMXIOVAMESOSPY
1 month -29.2%+34.8%-7.7% +0.9%
3 months -0.6%+224.8%-5.2% +5.9%
6 months -5.9%+347.4%-13.9% +8.5%
Year to date +55.3%+442.5%-25.8% +13.3%
1 year +108.2%+576.3%-20.0% +12.4%
3 years +139.5%+323.1%+472.2% +88.1%
3 years, per year +33.8%+61.8%+78.9% +23.5%
5 years —-39.1%+10.7% +68.2%
5 years, per year —-9.4%+2.0% +11.0%
10 years —+137.0%+55.0% +263.4%
10 years, per year —+9.0%+4.5% +13.8%

Risk

MeasureIMMXIOVAMESOSPY
Volatility, 1Y 82.8%99.0%54.8% 12.7%
Downside volatility, 1Y 76.3%71.1%54.9% 12.7%
Beta vs S&P 500, 1Y 1.571.291.53 1.00
Return / volatility, 1Y 1.315.82-0.36 0.98
Max drawdown, 5Y -88.9%-93.4%-87.9% -25.4%
From 52-week high -43.9%-0.3%-36.1% -0.9%
52-week high $14.47$14.86$20.96 $779.14
52-week low $3.03$1.81$11.95 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIMMXIOVAMESO
P/E now vs peer median -13.0xmedian 17.4x -23.0xmedian 17.4x -30.2xmedian 17.4x
P/S now vs peer median —median 9.1x 20.6xmedian 9.1x 14.4xmedian 9.1x
EV/EBITDA now vs peer median -8.4xmedian 17.1x -24.2xmedian 17.1x —median 17.1x
P/FCF now vs peer median -14.9xmedian 19.0x -22.6xmedian 19.0x -38.8xmedian 19.0x
P/B now vs peer median 2.5xmedian 2.2x 9.1xmedian 2.2x 3.1xmedian 2.2x
PEG now vs peer median -2.10median 0.34 -0.77median 0.34 —median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIMMXIOVAMESO
Revenue – $324.97M –
Gross profit – $157.29M –
Operating income -$41.82M -$301.31M –
Net income -$39.88M -$289.51M –
Free cash flow -$39.09M -$296.40M –
R&D $21.62M $267.72M –
EPS (diluted) $-0.63 $-0.64 –
Cash & equivalents $225.49M $110.80M $102.91M
Total debt – – $119.24M
Shares (diluted) 63.77M 450.19M 129.49M
Enterprise value $276.01M $3.11B $1.59B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIMMXIOVAMESO
P/E -13.0x -23.0x -30.2x
P/FCF -14.9x -22.6x -38.8x
P/Operating cash flow -15.1x -25.4x –
P/S – 20.6x 14.4x
P/B 2.5x 9.1x 3.1x
P/Tangible book 2.5x 14.2x 3.1x
EV/EBITDA -8.4x -24.2x –
EV/EBIT -8.3x -21.3x –
EV/Revenue – 19.7x –
EV/FCF -8.9x -21.6x –
EV/Operating cash flow -9.1x -24.3x –
PEG (3Y EPS CAGR) -2.10 -0.77 –

Growth

14 metrics
MetricIMMXIOVAMESO
Revenue growth (1Y) – 34.5% –
Revenue CAGR (3Y) – 1,009% –
Gross profit growth (1Y) – 95.1% –
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) -75.8% 26.6% –
Operating income CAGR (3Y) -53.5% 11.1% –
Net income growth (1Y) -72.4% 25.8% –
Net income CAGR (3Y) -51.7% 11.6% –
EPS growth (1Y) 18.9% 44.8% –
EPS CAGR (3Y) 6.2% 29.9% –
Operating cash flow growth (1Y) -207.8% 12.9% –
Operating cash flow CAGR (3Y) -51.9% 7.6% –
Free cash flow growth (1Y) -190.0% 8.4% –
Free cash flow CAGR (3Y) -52.7% 5.8% –

Profitability

14 metrics
MetricIMMXIOVAMESO
Gross margin – 48.4% –
EBITDA margin – -81.4% –
Operating margin – -92.7% –
Pretax margin – -90.4% –
Net margin – -89.1% –
FCF margin – -91.2% –
Operating cash flow margin – -81.3% –
Return on equity -25.5% -39.7% –
Return on assets -23.8% -31.4% –
Return on invested capital – – –
Return on capital employed -26.4% -37.0% –
Asset turnover – 0.4x –
Cash conversion (OCF / net income) 1.0x 0.9x –
Stock comp / revenue – 14.4% –

Financial Health

11 metrics
MetricIMMXIOVAMESO
Debt / assets – – 15.4%
Debt / equity – – 0.2x
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 4.3% 19.6% 26.5%
Equity / assets 95.7% 80.4% 73.5%
Interest coverage – – –
Current ratio 25.1x 4.3x 2.4x
Quick ratio 25.0x 3.7x 2.0x
Cash ratio 25.0x 2.8x 1.3x
Altman Z-score – 17.73 –

Shareholder Returns

7 metrics
MetricIMMXIOVAMESO
Dividend yield – – –
Net buyback yield -42.8% -4.4% –
Shareholder yield -42.8% -4.4% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIMMXIOVAMESO
EPS, next fiscal year $-0.70FY2026 $-0.47FY2026 $-0.15FY2027
Revenue, next fiscal year $0.00FY2026 $434.71MFY2026 $188.99MFY2027
Revenue growth, next FY – +65.0%FY2026 +57.2%FY2027
Revenue growth, the year after – +33.0% +110.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIMMXIOVAMESO
Held by institutions 78.6% 63.3% 3.0%
Institutions holding 110 292 73
Change in shares held, QoQ +107.6% +6.5% +17.7%
Institutions buying 81 174 34
Institutions selling 13 66 20
Buyers to sellers 6.23 2.64 1.70

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IMMXIOVAMESO
IMMX 1.00 0.25 0.23
IOVA 0.25 1.00 0.29
MESO 0.23 0.29 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, IMMX, IOVA and MESO?

Iovance Biotherapeutics (IOVA) is the largest by market capitalisation: Immix Biopharma (IMMX) $508.11M, Iovance Biotherapeutics (IOVA) $4.32B, Mesoblast (MESO) $2.02B.

Which stock has performed better?

Over the past year Iovance Biotherapeutics (IOVA) returned the most: Immix Biopharma (IMMX) +108.2%, Iovance Biotherapeutics (IOVA) +576.3%, Mesoblast (MESO) -20.0%. Over five years, Mesoblast (MESO) compounded fastest (Iovance Biotherapeutics (IOVA) -9.4%/yr, Mesoblast (MESO) +2.0%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Mesoblast (MESO) has been the steadiest (Immix Biopharma (IMMX) 82.8%, Iovance Biotherapeutics (IOVA) 99.0%, Mesoblast (MESO) 54.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IMMX, IOVA and MESO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iovance Biotherapeutics (IOVA) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.