ILMN vs TMO vs DHR Stock Comparison

Illumina, Thermo Fisher Scientific and Danaher Prices as of Oct 23, 2026 Peers: Industry group
ILMN Illumina, Inc.
$269.42 +5.5% 1M +169.5% 1Y
Market cap
$40.91B
P/E
49.6x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
5 wins
DHR Danaher Corp /De/
$230.44 +3.9% 1M +3.5% 1Y
Market cap
$164.19B
P/E
41.0x
Revenue (TTM)
$25.11B
Div. yield
–
Life Sciences Tools Healthcare
1 win

Head to Head

11 decided of 12

Thermo Fisher Scientific leads on 5 of the 12 questions below (Thermo Fisher Scientific 5, Illumina 5, Danaher 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionILMNTMODHRLeader
Larger companyMarket capitalisation $40.91B $254.18B $164.19B TMO
Cheaper on earningsLower P/E, profitable companies only 49.6x 36.5x 41.0x TMO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 53.9x 26.1x 25.5x DHR
Faster revenue growthRevenue growth, trailing twelve months +4.9% +7.2% +4.6% TMO
More profitableNet margin, trailing twelve months 18.4% 15.0% 15.9% ILMN
Better return on capitalReturn on invested capital 15.1% 7.9% 5.7% ILMN
Less leveragedLower net debt / EBITDA 0.7x 3.5x 2.9x ILMN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +169.5% +17.8% +3.5% ILMN
Better 5-year returnAnnualised price return, 5 years -7.5%/yr +1.9%/yr -6.0%/yr TMO
Less volatileAnnualised volatility, 1 year 50.3% 29.8% 30.6% TMO
Higher overall scoreMean of the five percentile scores vs peers 65/100 59/100 60/100 ILMN

Percentile Scorecard

ILMNTMODHR

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisILMNTMODHR
Valuation 52 #111 of 228 60 #93 of 228 67 #75 of 228
Growth 43 #126 of 222 35 #144 of 222 20 #178 of 222
Profitability 97 #7 of 210 83 #37 of 210 88 #27 of 210
Financial Health 51 #118 of 241 28 #174 of 241 46 #131 of 241
Shareholder Returns 84 #23 of 138 88 #18 of 138 77 #32 of 138
Overall 65 59 60
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • DHR ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodILMNTMODHRSPY
1 month +5.5%+1.2%+3.9% -1.0%
3 months +38.8%+18.6%+20.3% +2.9%
6 months +110.7%+43.5%+30.0% +6.4%
Year to date +105.4%+16.3%+0.7% +11.4%
1 year +169.5%+17.8%+3.5% +13.1%
3 years +138.6%+47.1%+17.1% +79.4%
3 years, per year +33.6%+13.7%+5.4% +21.5%
5 years -32.3%+10.1%-26.5% +67.7%
5 years, per year -7.5%+1.9%-6.0% +10.9%
10 years +95.3%+347.3%+187.4% +255.2%
10 years, per year +6.9%+16.2%+11.1% +13.5%

Risk

MeasureILMNTMODHRSPY
Volatility, 1Y 50.3%29.8%30.6% 12.7%
Downside volatility, 1Y 39.1%28.3%31.7% 12.7%
Beta vs S&P 500, 1Y 0.800.590.44 1.00
Return / volatility, 1Y 3.370.600.11 1.03
Max drawdown, 5Y -82.9%-41.5%-50.8% -25.4%
From 52-week high -8.3%-3.3%-4.8% -2.5%
52-week high $293.69$696.55$242.05 $779.14
52-week low $95.03$438.34$161.91 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleILMNTMODHR
P/E now vs peer median 49.3xmedian 30.7x 35.9xmedian 30.7x 40.6xmedian 30.7x
P/S now vs peer median 9.1xmedian 3.0x 5.4xmedian 3.0x 6.5xmedian 3.0x
EV/EBITDA now vs peer median 36.0xmedian 17.7x 25.9xmedian 17.7x 24.0xmedian 17.7x
P/FCF now vs peer median 43.7xmedian 23.7x 34.0xmedian 23.7x 29.6xmedian 23.7x
P/B now vs peer median 14.3xmedian 2.4x 4.7xmedian 2.4x 3.1xmedian 2.4x
PEG now vs peer median 1.64median 0.96 4.27median 0.96 -3.24median 0.96

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsILMNTMODHR
Revenue $4.49B $46.34B $25.11B
Gross profit $2.98B $18.91B $14.69B
Operating income $882.00M $8.15B $5.13B
Net income $825.00M $6.99B $4.00B
Free cash flow $931.00M $7.32B $5.47B
R&D $960.00M $1.40B $1.62B
EPS (diluted) $5.39 $18.78 $5.66
Cash & equivalents $1.04B $4.06B $4.35B
Total debt $6.97B $42.55B $26.56B
Shares (diluted) 153.00M 371.00M 707.60M
Enterprise value $35.68B $233.20B $148.00B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricILMNTMODHR
P/E 49.3x 35.9x 40.6x
P/FCF 43.7x 34.0x 29.6x
P/Operating cash flow 37.2x 27.6x 24.4x
P/S 9.1x 5.4x 6.5x
P/B 14.3x 4.7x 3.1x
P/Tangible book 16.8x 7.3x 5.2x
EV/EBITDA 36.0x 25.9x 24.0x
EV/EBIT 47.1x 35.3x 35.9x
EV/Revenue 9.2x 6.2x 7.3x
EV/FCF 44.6x 39.3x 33.7x
EV/Operating cash flow 37.9x 31.9x 27.8x
PEG (3Y EPS CAGR) 1.64 4.27 -3.24

Growth

14 metrics
MetricILMNTMODHR
Revenue growth (1Y) 4.9% 7.2% 4.6%
Revenue CAGR (3Y) -1.0% 2.1% -0.5%
Gross profit growth (1Y) 4.6% 6.2% 2.6%
Gross profit CAGR (3Y) 2.9% 3.0% -0.9%
Operating income growth (1Y) -31.8% 10.0% 16.1%
Operating income CAGR (3Y) 28.3% 6.7% -7.1%
Net income growth (1Y) -34.4% 6.2% 17.3%
Net income CAGR (3Y) 30.0% 6.9% -14.3%
EPS growth (1Y) -32.7% 7.8% 19.2%
EPS CAGR (3Y) 30.1% 8.4% -12.5%
Operating cash flow growth (1Y) -5.1% 18.9% 7.6%
Operating cash flow CAGR (3Y) 38.1% 5.4% -7.6%
Free cash flow growth (1Y) -9.7% 18.6% 12.4%
Free cash flow CAGR (3Y) 105.0% 7.7% -9.0%

Profitability

14 metrics
MetricILMNTMODHR
Gross margin 66.4% 40.8% 58.5%
EBITDA margin 25.7% 23.9% 30.5%
Operating margin 19.6% 17.6% 20.4%
Pretax margin 22.6% 16.5% 19.0%
Net margin 18.4% 15.0% 15.9%
FCF margin 20.7% 15.8% 21.8%
Operating cash flow margin 24.4% 19.5% 26.4%
Return on equity 29.9% 13.4% 7.6%
Return on assets 12.5% 6.2% 4.5%
Return on invested capital 15.1% 7.9% 5.7%
Return on capital employed 17.5% 8.3% 6.4%
Asset turnover 0.7x 0.4x 0.3x
Cash conversion (OCF / net income) 1.3x 1.3x 1.7x
Stock comp / revenue 5.9% 0.7% 1.2%

Financial Health

11 metrics
MetricILMNTMODHR
Debt / assets 29.9% 37.6% 28.8%
Debt / equity 0.7x 0.8x 0.5x
Net debt / EBITDA 0.7x 3.5x 2.9x
Debt / FCF 2.1x 5.8x 4.9x
Liabilities / assets 57.3% 53.4% 43.1%
Equity / assets 42.7% 46.6% 56.9%
Interest coverage 8.9x 5.6x 17.6x
Current ratio 1.8x 1.6x 1.7x
Quick ratio 1.2x 1.0x 1.0x
Cash ratio 0.7x 0.3x 0.5x
Altman Z-score 7.73 3.98 3.70

Shareholder Returns

7 metrics
MetricILMNTMODHR
Dividend yield – 0.3% 0.7%
Net buyback yield 1.2% 2.0% 1.8%
Shareholder yield 1.2% 2.3% 2.5%
Payout ratio (earnings) – 9.5% –
Payout ratio (FCF) – 9.0% –
Dividend growth (1Y) – 8.5% –
Dividend CAGR (3Y) – 10.8% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusILMNTMODHR
Forward P/E 53.9xFY2026 26.1xFY2026 25.5xFY2026
EPS, next fiscal year $5.00FY2026 $25.77FY2026 $9.03FY2026
EPS growth, next FY +3.3%FY2026 +12.7%FY2026 +15.8%FY2026
EPS growth, the year after +25.4% +1.8% +8.9%
Revenue, next fiscal year $4.52BFY2026 $49.99BFY2026 $27.12BFY2026
Revenue growth, next FY +4.1%FY2026 +12.2%FY2026 +10.4%FY2026
Revenue growth, the year after +12.0% -2.9% -1.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersILMNTMODHR
Held by institutions 100.0% 90.2% 81.9%
Institutions holding 933 2,621 2,115
Change in shares held, QoQ +0.0% +0.8% +1.1%
Institutions buying 463 1,141 837
Institutions selling 330 1,144 1,015
Buyers to sellers 1.40 1.00 0.82

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ILMNTMODHR
ILMN 1.00 0.50 0.34
TMO 0.50 1.00 0.72
DHR 0.34 0.72 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ILMN, TMO and DHR?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Illumina (ILMN) $40.91B, Thermo Fisher Scientific (TMO) $254.18B, Danaher (DHR) $164.19B.

Which stock is cheaper, ILMN, TMO and DHR?

Thermo Fisher Scientific (TMO) trades on the lowest price-to-earnings ratio (Illumina (ILMN) 49.6x, Thermo Fisher Scientific (TMO) 36.5x, Danaher (DHR) 41.0x). On next year's consensus earnings, Danaher (DHR) is cheapest (Illumina (ILMN) 53.9x, Thermo Fisher Scientific (TMO) 26.1x, Danaher (DHR) 25.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +4.9%, Thermo Fisher Scientific (TMO) +7.2%, Danaher (DHR) +4.6%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Illumina (ILMN) 18.4%, Thermo Fisher Scientific (TMO) 15.0%, Danaher (DHR) 15.9%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 15.1%, Thermo Fisher Scientific (TMO) 7.9%, Danaher (DHR) 5.7%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Illumina (ILMN) +169.5%, Thermo Fisher Scientific (TMO) +17.8%, Danaher (DHR) +3.5%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Illumina (ILMN) -7.5%/yr, Thermo Fisher Scientific (TMO) +1.9%/yr, Danaher (DHR) -6.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Illumina (ILMN) 0.00%, Thermo Fisher Scientific (TMO) 0.00%, Danaher (DHR) 0.00%. Illumina (ILMN) and Danaher (DHR) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Illumina (ILMN) 50.3%, Thermo Fisher Scientific (TMO) 29.8%, Danaher (DHR) 30.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ILMN, TMO and DHR?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Thermo Fisher Scientific (TMO) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.