ILMN vs A vs TMO Stock Comparison

Illumina, Agilent Technologies and Thermo Fisher Scientific Prices as of Oct 26, 2026 Peers: Industry group
ILMN Illumina, Inc.
$271.04 +0.4% 1M +170.7% 1Y
Market cap
$42.15B
P/E
51.1x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
4 wins
A Agilent Technologies, Inc.
$175.96 +1.8% 1M +18.9% 1Y
Market cap
$50.11B
P/E
34.8x
Revenue (TTM)
$7.37B
Div. yield
0.01%
Life Sciences Tools Healthcare
4 wins

Head to Head

11 decided of 12

Agilent Technologies leads on 4 of the 12 questions below (Agilent Technologies 4, Illumina 4, Thermo Fisher Scientific 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionILMNATMOLeader
Larger companyMarket capitalisation $42.15B $50.11B $257.67B TMO
Cheaper on earningsLower P/E, profitable companies only 51.1x 34.8x 36.4x A
Cheaper on forward earningsLower price / next fiscal year consensus EPS 54.3x 26.9x 26.4x TMO
Faster revenue growthRevenue growth, trailing twelve months +4.9% +8.6% +8.3% A
More profitableNet margin, trailing twelve months 18.4% 19.5% — A
Better return on capitalReturn on invested capital 15.1% 13.1% — ILMN
Less leveragedLower net debt / EBITDA 0.7x 1.1x — ILMN
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months +170.7% +18.9% +19.6% ILMN
Better 5-year returnAnnualised price return, 5 years -7.5%/yr +2.5%/yr +2.3%/yr A
Less volatileAnnualised volatility, 1 year 50.4% 32.4% 29.9% TMO
Higher overall scoreMean of the five percentile scores vs peers 65/100 62/100 51/100 ILMN

Percentile Scorecard

ILMNATMO

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisILMNATMO
Valuation 52 #111 of 228 58 #97 of 228 49 #116 of 228
Growth 44 #124 of 221 36 #141 of 221 40 #133 of 221
Profitability 97 #7 of 208 91 #20 of 208 70 #63 of 208
Financial Health 51 #118 of 239 55 #108 of 239 –
Shareholder Returns 84 #23 of 137 71 #40 of 137 44 #77 of 137
Overall 65 62 51
  • ILMN ranked among 248 companies in Medical Devices and Diagnostics
  • A ranked among 248 companies in Medical Devices and Diagnostics
  • TMO ranked among 248 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodILMNATMOSPY
1 month +0.4%+1.8%+1.7% -0.8%
3 months +43.1%+27.6%+22.4% +3.5%
6 months +110.9%+52.2%+46.3% +7.0%
Year to date +106.6%+29.3%+18.2% +12.2%
1 year +170.7%+18.9%+19.6% +13.0%
3 years +155.1%+71.2%+58.7% +86.3%
3 years, per year +36.7%+19.6%+16.7% +23.1%
5 years -32.4%+13.3%+11.8% +68.6%
5 years, per year -7.5%+2.5%+2.3% +11.0%
10 years +99.1%+305.7%+362.6% +258.0%
10 years, per year +7.1%+15.0%+16.6% +13.6%

Risk

MeasureILMNATMOSPY
Volatility, 1Y 50.4%32.4%29.9% 12.7%
Downside volatility, 1Y 39.1%27.5%28.3% 12.7%
Beta vs S&P 500, 1Y 0.810.880.62 1.00
Return / volatility, 1Y 3.390.580.66 1.02
Max drawdown, 5Y -82.9%-39.6%-41.5% -25.4%
From 52-week high -7.7%-1.0%-1.7% -1.8%
52-week high $293.69$177.72$696.55 $779.14
52-week low $95.03$110.24$438.34 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleILMNATMO
P/E now vs peer median 49.6xmedian 30.6x 34.5xmedian 30.6x 35.9xmedian 30.6x
P/S now vs peer median 9.1xmedian 3.0x 6.7xmedian 3.0x 5.3xmedian 3.0x
EV/EBITDA now vs peer median 36.2xmedian 17.5x 27.1xmedian 17.5x —median 17.5x
P/FCF now vs peer median 44.0xmedian 23.3x 39.2xmedian 23.3x 34.0xmedian 23.3x
P/B now vs peer median 14.4xmedian 2.4x 6.7xmedian 2.4x 4.6xmedian 2.4x
PEG now vs peer median 1.65median 0.87 3.51median 0.87 4.74median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsILMNATMO
Revenue $4.49B $7.37B $47.35B
Gross profit $2.98B $3.97B –
Operating income $882.00M $1.64B $8.47B
Net income $825.00M $1.44B $7.09B
Free cash flow $931.00M $1.27B –
R&D $960.00M $485.00M $1.40B
EPS (diluted) $5.39 $5.09 $19.06
Cash & equivalents $1.04B $1.76B $5.46B
Total debt $1.99B $3.95B –
Shares (diluted) 153.00M 283.00M 371.00M
Enterprise value $36.92B $42.99B $257.67B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricILMNATMO
P/E 49.6x 34.5x 35.9x
P/FCF 44.0x 39.2x 34.0x
P/Operating cash flow 37.4x 30.8x 27.2x
P/S 9.1x 6.7x 5.3x
P/B 14.4x 6.7x 4.6x
P/Tangible book 16.9x 7.7x 6.9x
EV/EBITDA 36.2x 27.1x –
EV/EBIT 47.3x 31.6x –
EV/Revenue 9.3x 7.0x 5.3x
EV/FCF 44.8x 40.9x –
EV/Operating cash flow 38.1x 32.2x 27.2x
PEG (3Y EPS CAGR) 1.65 3.51 4.74

Growth

14 metrics
MetricILMNATMO
Revenue growth (1Y) 4.9% 8.6% 8.3%
Revenue CAGR (3Y) -1.0% 1.8% 2.9%
Gross profit growth (1Y) 4.6% 11.2% –
Gross profit CAGR (3Y) 2.9% 3.7% –
Operating income growth (1Y) -31.8% 13.5% 12.8%
Operating income CAGR (3Y) 28.3% 5.1% 7.2%
Net income growth (1Y) -34.4% 18.0% 7.9%
Net income CAGR (3Y) 30.0% 8.3% 6.2%
EPS growth (1Y) -32.7% 18.9% 9.7%
EPS CAGR (3Y) 30.1% 9.8% 7.6%
Operating cash flow growth (1Y) -5.1% 7.6% 21.9%
Operating cash flow CAGR (3Y) 38.1% -1.9% 4.5%
Free cash flow growth (1Y) -9.7% 16.5% –
Free cash flow CAGR (3Y) 105.0% -3.7% –

Profitability

14 metrics
MetricILMNATMO
Gross margin 66.4% 53.8% –
EBITDA margin 25.7% 25.9% –
Operating margin 19.6% 22.2% –
Pretax margin 22.6% 22.5% –
Net margin 18.4% 19.5% –
FCF margin 20.7% 17.2% –
Operating cash flow margin 24.4% 21.8% 19.7%
Return on equity 29.9% 19.9% 13.2%
Return on assets 12.5% 10.7% 6.2%
Return on invested capital 15.1% 13.1% –
Return on capital employed 17.5% 14.6% –
Asset turnover 0.7x 0.5x 0.4x
Cash conversion (OCF / net income) 1.3x 1.1x 1.3x
Stock comp / revenue 5.9% 1.8% –

Financial Health

11 metrics
MetricILMNATMO
Debt / assets 29.9% 28.3% –
Debt / equity 0.7x 0.5x –
Net debt / EBITDA 0.7x 1.1x –
Debt / FCF 2.1x 3.1x –
Liabilities / assets 57.3% 47.3% –
Equity / assets 42.7% 52.7% 47.9%
Interest coverage 8.9x 15.5x –
Current ratio 1.8x 2.1x 1.8x
Quick ratio 1.2x 1.4x –
Cash ratio 0.7x 0.8x –
Altman Z-score 7.77 5.82 –

Shareholder Returns

7 metrics
MetricILMNATMO
Dividend yield – 0.6% 0.3%
Net buyback yield 1.2% 0.6% –
Shareholder yield 1.2% 1.2% 0.3%
Payout ratio (earnings) – 19.9% –
Payout ratio (FCF) – 22.6% –
Dividend growth (1Y) – 2.1% –
Dividend CAGR (3Y) – 3.1% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusILMNATMO
Forward P/E 54.3xFY2026 26.9xFY2026 26.4xFY2026
EPS, next fiscal year $4.99FY2026 $6.54FY2026 $25.91FY2026
EPS growth, next FY +3.1%FY2026 +17.0%FY2026 +13.3%FY2026
EPS growth, the year after +25.7% +0.3% +2.0%
Revenue, next fiscal year $4.52BFY2026 $7.87BFY2026 $50.12BFY2026
Revenue growth, next FY +4.1%FY2026 +15.3%FY2026 +12.5%FY2026
Revenue growth, the year after +12.0% -5.6% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersILMNATMO
Held by institutions 100.0% 92.6% 90.2%
Institutions holding 933 1,122 2,621
Change in shares held, QoQ +0.0% +3.2% +0.8%
Institutions buying 463 599 1,141
Institutions selling 330 350 1,144
Buyers to sellers 1.40 1.71 1.00

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ILMNATMO
ILMN 1.00 0.48 0.50
A 0.48 1.00 0.73
TMO 0.50 0.73 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ILMN, A and TMO?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Illumina (ILMN) $42.15B, Agilent Technologies (A) $50.11B, Thermo Fisher Scientific (TMO) $257.67B.

Which stock is cheaper, ILMN, A and TMO?

Agilent Technologies (A) trades on the lowest price-to-earnings ratio (Illumina (ILMN) 51.1x, Agilent Technologies (A) 34.8x, Thermo Fisher Scientific (TMO) 36.4x). On next year's consensus earnings, Thermo Fisher Scientific (TMO) is cheapest (Illumina (ILMN) 54.3x, Agilent Technologies (A) 26.9x, Thermo Fisher Scientific (TMO) 26.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Agilent Technologies (A) grew revenue fastest over the trailing twelve months: Illumina (ILMN) +4.9%, Agilent Technologies (A) +8.6%, Thermo Fisher Scientific (TMO) +8.3%.

Which company is more profitable?

Agilent Technologies (A) has the highest net margin (Illumina (ILMN) 18.4%, Agilent Technologies (A) 19.5%). On return on invested capital, Illumina (ILMN) leads (Illumina (ILMN) 15.1%, Agilent Technologies (A) 13.1%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Illumina (ILMN) +170.7%, Agilent Technologies (A) +18.9%, Thermo Fisher Scientific (TMO) +19.6%. Over five years, Agilent Technologies (A) compounded fastest (Illumina (ILMN) -7.5%/yr, Agilent Technologies (A) +2.5%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Illumina (ILMN) 0.00%, Agilent Technologies (A) 0.01%, Thermo Fisher Scientific (TMO) 0.00%. Illumina (ILMN) and Thermo Fisher Scientific (TMO) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Illumina (ILMN) 50.4%, Agilent Technologies (A) 32.4%, Thermo Fisher Scientific (TMO) 29.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ILMN, A and TMO?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Agilent Technologies (A) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.