IDXG vs GH vs SHC Stock Comparison

Interpace Biosciences, Guardant Health and Sotera Health Prices as of Oct 28, 2026 Peers: Industry group
GH Guardant Health, Inc.
$182.59 +3.0% 1M +162.4% 1Y
Market cap
$24.39B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
SHC Sotera Health Co
$18.65 +1.1% 1M +12.6% 1Y
Market cap
$5.36B
P/E
32.8x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
1 win

Head to Head

8 decided of 12

Interpace Biosciences leads on 4 of the 12 questions below (Interpace Biosciences 4, Guardant Health 3, Sotera Health 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionIDXGGHSHCLeader
Larger companyMarket capitalisation $138.51M $24.39B $5.36B GH
Cheaper on earningsLower P/E, profitable companies only 5.7x -53.8x 32.8x IDXG
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 20.3x –
Faster revenue growthRevenue growth, trailing twelve months -20.5% +42.7% +8.1% GH
More profitableNet margin, trailing twelve months 67.6% -38.3% 13.4% IDXG
Better return on capitalReturn on invested capital — — 9.1% –
Less leveragedLower net debt / EBITDA — — 3.3x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +334.2% +162.4% +12.6% IDXG
Better 5-year returnAnnualised price return, 5 years — +9.4%/yr -5.5%/yr GH
Less volatileAnnualised volatility, 1 year 182.0% 57.3% 28.4% SHC
Higher overall scoreMean of the five percentile scores vs peers 66/100 28/100 59/100 IDXG

Percentile Scorecard

IDXGGHSHC

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisIDXGGHSHC
Valuation 59 #38 of 92 18 #76 of 92 52 #45 of 92
Growth 47 #47 of 87 48 #46 of 87 67 #29 of 87
Profitability 92 #8 of 86 7 #80 of 86 82 #16 of 86
Financial Health 67 #33 of 97 53 #46 of 97 35 #63 of 97
Shareholder Returns – 15 #47 of 55 –
Overall 66 28 59
  • IDXG ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers
  • SHC ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodIDXGGHSHCSPY
1 month -22.9%+3.0%+1.1% +0.9%
3 months +219.4%+26.7%+6.4% +5.9%
6 months +148.7%+118.9%+20.7% +8.5%
Year to date +302.4%+78.8%+5.7% +13.3%
1 year +334.2%+162.4%+12.6% +12.4%
3 years —+631.5%+49.1% +88.1%
3 years, per year —+94.2%+14.2% +23.5%
5 years —+56.3%-24.5% +68.2%
5 years, per year —+9.4%-5.5% +11.0%

Risk

MeasureIDXGGHSHCSPY
Volatility, 1Y 182.0%57.3%28.4% 12.7%
Downside volatility, 1Y 84.2%48.9%27.1% 12.7%
Beta vs S&P 500, 1Y -0.051.041.01 1.00
Return / volatility, 1Y 1.842.830.44 0.98
Max drawdown, 5Y -81.1%-86.7%-78.2% -25.4%
From 52-week high -35.0%-2.5%-4.7% -0.9%
52-week high $7.62$187.22$19.57 $779.14
52-week low $0.83$69.58$13.13 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleIDXGGHSHC
P/E now vs peer median 5.6xmedian 25.6x -53.5xmedian 25.6x 32.6xmedian 25.6x
P/S now vs peer median 3.8xmedian 1.6x 20.6xmedian 1.6x 4.4xmedian 1.6x
EV/EBITDA now vs peer median 28.8xmedian 16.3x -54.1xmedian 16.3x 13.1xmedian 16.3x
P/FCF now vs peer median 33.4xmedian 21.3x -101.3xmedian 21.3x 47.2xmedian 21.3x
P/B now vs peer median 5.9xmedian 3.3x -109.5xmedian 3.3x 8.0xmedian 3.3x
PEG now vs peer median 0.18median 0.68 -5.39median 0.68 0.87median 0.68

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsIDXGGHSHC
Revenue $36.14M $1.18B $1.22B
Gross profit $23.04M $769.16M $668.51M
Operating income $4.17M -$470.26M $411.34M
Net income $24.45M -$453.44M $163.48M
Free cash flow $4.10M -$240.72M $112.70M
R&D $594.00K $375.79M –
EPS (diluted) $0.88 $-3.41 $0.57
Cash & equivalents $2.70M $1.05B $356.72M
Total debt – – $2.14B
Shares (diluted) 27.71M 132.87M 288.15M
Enterprise value $129.23M $20.45B $4.05B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricIDXGGHSHC
P/E 5.6x -53.5x 32.6x
P/FCF 33.4x -101.3x 47.2x
P/Operating cash flow 30.8x -131.7x 18.2x
P/S 3.8x 20.6x 4.4x
P/B 5.9x -109.5x 8.0x
P/Tangible book 5.9x -98.3x 13.5x
EV/EBITDA 28.8x -54.1x 13.1x
EV/EBIT 32.3x -49.6x 17.3x
EV/Revenue 3.7x 19.7x 5.8x
EV/FCF 32.8x -97.0x 63.0x
EV/Operating cash flow 30.2x -126.1x 24.3x
PEG (3Y EPS CAGR) 0.18 -5.39 0.87

Growth

14 metrics
MetricIDXGGHSHC
Revenue growth (1Y) -20.5% 42.7% 8.1%
Revenue CAGR (3Y) -1.0% 32.4% 7.6%
Gross profit growth (1Y) -19.0% 47.7% 7.1%
Gross profit CAGR (3Y) -0.1% – 8.1%
Operating income growth (1Y) -27.2% -2.1% 21.8%
Operating income CAGR (3Y) 46.4% 4.8% 23.2%
Net income growth (1Y) 435.6% -9.6% 580.5%
Net income CAGR (3Y) 54.2% 3.7% 37.7%
EPS growth (1Y) -14.5% -2.4% 574.9%
EPS CAGR (3Y) 31.2% 9.9% 37.5%
Operating cash flow growth (1Y) -11.8% 22.4% 9.8%
Operating cash flow CAGR (3Y) 62.1% 18.1% 61.3%
Free cash flow growth (1Y) -6.8% 11.4% 0.0%
Free cash flow CAGR (3Y) 54.9% 14.4% 32.6%

Profitability

14 metrics
MetricIDXGGHSHC
Gross margin 63.7% 65.0% 55.0%
EBITDA margin 12.9% -36.5% 44.6%
Operating margin 11.5% -39.7% 33.8%
Pretax margin 11.1% -38.4% 21.7%
Net margin 67.6% -38.3% 13.4%
FCF margin 11.4% -20.3% 9.3%
Operating cash flow margin 12.3% -15.7% 24.0%
Return on equity 105.5% – 25.4%
Return on assets 72.0% -23.7% 5.0%
Return on invested capital – – 9.1%
Return on capital employed 14.4% -29.9% 13.5%
Asset turnover 1.1x 0.6x 0.4x
Cash conversion (OCF / net income) 0.2x 0.4x 1.8x
Stock comp / revenue 0.1% 16.2% 3.1%

Financial Health

11 metrics
MetricIDXGGHSHC
Debt / assets – – 64.7%
Debt / equity – – 3.2x
Net debt / EBITDA – – 3.3x
Debt / FCF – – 19.0x
Liabilities / assets 32.7% 111.7% 79.9%
Equity / assets 67.3% -11.7% 20.1%
Interest coverage – -97.6x –
Current ratio 2.2x 4.0x 2.8x
Quick ratio 1.8x 3.5x 2.4x
Cash ratio 0.5x 3.1x 1.5x
Altman Z-score 0.42 4.94 1.95

Shareholder Returns

7 metrics
MetricIDXGGHSHC
Dividend yield – – –
Net buyback yield – -1.6% –
Shareholder yield – -1.6% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusIDXGGHSHC
Forward P/E – – 20.3xFY2026
EPS, next fiscal year $-0.72FY2023 $-3.33FY2026 $0.92FY2026
EPS growth, next FY – – +7.0%FY2026
EPS growth, the year after – – +21.7%
Revenue, next fiscal year – $1.42BFY2026 $1.33BFY2026
Revenue growth, next FY – +44.5%FY2026 +14.8%FY2026
Revenue growth, the year after – +27.0% -4.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersIDXGGHSHC
Held by institutions – 100.0% 100.0%
Institutions holding – 594 316
Change in shares held, QoQ – -2.6% +5.9%
Institutions buying – 353 220
Institutions selling – 180 64
Buyers to sellers – 1.96 3.44

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

IDXGGHSHC
IDXG 1.00 -0.03 -0.01
GH -0.03 1.00 0.28
SHC -0.01 0.28 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, IDXG, GH and SHC?

Guardant Health (GH) is the largest by market capitalisation: Interpace Biosciences (IDXG) $138.51M, Guardant Health (GH) $24.39B, Sotera Health (SHC) $5.36B.

Which stock is cheaper, IDXG, GH and SHC?

Interpace Biosciences (IDXG) trades on the lowest price-to-earnings ratio (Interpace Biosciences (IDXG) 5.7x, Guardant Health (GH) -53.8x, Sotera Health (SHC) 32.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Interpace Biosciences (IDXG) -20.5%, Guardant Health (GH) +42.7%, Sotera Health (SHC) +8.1%.

Which company is more profitable?

Interpace Biosciences (IDXG) has the highest net margin (Interpace Biosciences (IDXG) 67.6%, Guardant Health (GH) -38.3%, Sotera Health (SHC) 13.4%).

Which stock has performed better?

Over the past year Interpace Biosciences (IDXG) returned the most: Interpace Biosciences (IDXG) +334.2%, Guardant Health (GH) +162.4%, Sotera Health (SHC) +12.6%. Over five years, Guardant Health (GH) compounded fastest (Guardant Health (GH) +9.4%/yr, Sotera Health (SHC) -5.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Interpace Biosciences (IDXG) 182.0%, Guardant Health (GH) 57.3%, Sotera Health (SHC) 28.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, IDXG, GH and SHC?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Interpace Biosciences (IDXG) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.