ICLR vs MEDP vs CRL Stock Comparison

Icon, Medpace Holdings and Charles River Laboratories International Prices as of Oct 29, 2026 Peers: Industry group
ICLR Icon Plc
$215.48 +26.5% 1M +29.8% 1Y
Market cap
$16.50B
P/E
37.7x
Revenue (TTM)
$8.23B
Div. yield
–
Contract Research Healthcare
4 wins
MEDP Medpace Holdings, Inc.
$677.56 +8.9% 1M +15.9% 1Y
Market cap
$18.95B
P/E
36.6x
Revenue (TTM)
$2.84B
Div. yield
–
Contract Research Healthcare
6 wins

Head to Head

11 decided of 12

Medpace Holdings leads on 6 of the 12 questions below (Medpace Holdings 6, Icon 4, Charles River Laboratories International 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionICLRMEDPCRLLeader
Larger companyMarket capitalisation $16.50B $18.95B $17.94B MEDP
Cheaper on earningsLower P/E, profitable companies only 37.7x 36.6x -75.7x MEDP
Cheaper on forward earningsLower price / next fiscal year consensus EPS 21.0x 38.1x 34.5x ICLR
Faster revenue growthRevenue growth, trailing twelve months +1.8% +20.4% -0.7% MEDP
More profitableNet margin, trailing twelve months 5.4% 18.2% -6.0% MEDP
Better return on capitalReturn on invested capital 4.7% — 1.6% ICLR
Less leveragedLower net debt / EBITDA 2.3x — 6.3x ICLR
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +29.8% +15.9% +108.6% CRL
Better 5-year returnAnnualised price return, 5 years -5.6%/yr +24.5%/yr -3.5%/yr MEDP
Less volatileAnnualised volatility, 1 year 75.0% 45.6% 45.7% MEDP
Higher overall scoreMean of the five percentile scores vs peers 81/100 78/100 43/100 ICLR

Percentile Scorecard

ICLRMEDPCRL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisICLRMEDPCRL
Valuation 100 #1 of 11 60 #5 of 11 50 #6 of 11
Growth 70 #4 of 11 100 #1 of 11 10 #10 of 11
Profitability 80 #3 of 11 100 #1 of 11 70 #4 of 11
Financial Health 75 #4 of 13 50 #7 of 13 42 #8 of 13
Shareholder Returns – – –
Overall 81 78 43
  • ICLR ranked among 13 companies in Pharma Services
  • MEDP ranked among 13 companies in Pharma Services
  • CRL ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodICLRMEDPCRLSPY
1 month +26.5%+8.9%+26.8% +0.7%
3 months +30.2%+17.2%+60.2% +3.7%
6 months +82.1%+61.8%+125.1% +7.1%
Year to date +18.3%+20.6%+88.4% +12.8%
1 year +29.8%+15.9%+108.6% +11.9%
3 years -9.5%+180.2%+128.4% +85.2%
3 years, per year -3.3%+41.0%+31.7% +22.8%
5 years -24.9%+199.1%-16.2% +67.6%
5 years, per year -5.6%+24.5%-3.5% +10.9%
10 years +168.3%+2,245.3%+394.5% +262.0%
10 years, per year +10.4%+37.1%+17.3% +13.7%

Risk

MeasureICLRMEDPCRLSPY
Volatility, 1Y 75.0%45.6%45.7% 12.7%
Downside volatility, 1Y 87.7%53.9%42.5% 12.6%
Beta vs S&P 500, 1Y 1.470.691.28 1.00
Return / volatility, 1Y 0.400.352.38 0.94
Max drawdown, 5Y -76.9%-42.9%-77.3% -25.4%
From 52-week high 0.0%-2.2%0.0% -1.2%
52-week high $215.48$692.68$375.83 $779.14
52-week low $80.08$393.42$149.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleICLRMEDPCRL
P/E now vs peer median 37.7xmedian 36.6x 36.6xmedian 36.6x -75.7xmedian 36.6x
P/S now vs peer median 2.0xmedian 2.6x 6.7xmedian 2.6x 4.5xmedian 2.6x
EV/EBITDA now vs peer median 17.4xmedian 31.1x 28.8xmedian 31.1x 52.5xmedian 31.1x
P/FCF now vs peer median 19.3xmedian 21.8x 28.4xmedian 21.8x 48.4xmedian 21.8x
P/B now vs peer median 1.8xmedian 3.1x 32.4xmedian 3.1x 6.3xmedian 3.1x
PEG now vs peer median -15.86median 2.05 1.28median 2.05 2.09median 2.05

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsICLRMEDPCRL
Revenue $8.23B $2.84B $4.00B
Gross profit $1.93B $827.16M $1.31B
Operating income $718.25M $607.14M $90.14M
Net income $448.66M $517.83M -$239.23M
Free cash flow $857.06M $667.63M $370.61M
EPS (diluted) $5.68 $18.25 $-4.97
Cash & equivalents $808.98M $705.32M $192.03M
Total debt $3.38B – $2.62B
Shares (diluted) 78.97M 28.37M 48.02M
Enterprise value $13.27B $16.59B $17.18B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricICLRMEDPCRL
P/E 37.7x 36.6x -75.7x
P/FCF 19.3x 28.4x 48.4x
P/Operating cash flow 16.1x 26.2x 30.8x
P/S 2.0x 6.7x 4.5x
P/B 1.8x 32.4x 6.3x
P/Tangible book 2.7x 34.3x 6.9x
EV/EBITDA 17.4x 28.8x 52.5x
EV/EBIT 26.5x 30.0x 225.9x
EV/Revenue 2.3x 6.4x 5.1x
EV/FCF 22.2x 27.3x 55.0x
EV/Operating cash flow 18.6x 25.2x 35.0x
PEG (3Y EPS CAGR) -15.86 1.28 2.09

Growth

14 metrics
MetricICLRMEDPCRL
Revenue growth (1Y) 1.8% 20.4% -0.7%
Revenue CAGR (3Y) 0.9% 16.8% -1.5%
Gross profit growth (1Y) -13.4% 12.8% -0.1%
Gross profit CAGR (3Y) -6.5% 18.0% -5.5%
Operating income growth (1Y) 53.9% 19.7% -27.6%
Operating income CAGR (3Y) -7.0% 23.0% -48.2%
Net income growth (1Y) 55.9% 19.6% -268.7%
Net income CAGR (3Y) -4.4% 23.8% -35.5%
EPS growth (1Y) 30.1% 21.5% -253.8%
EPS CAGR (3Y) -2.4% 28.5% -36.2%
Operating cash flow growth (1Y) -9.9% 1.7% -26.1%
Operating cash flow CAGR (3Y) 15.8% 20.5% -2.3%
Free cash flow growth (1Y) -11.1% -1.4% -35.9%
Free cash flow CAGR (3Y) 18.4% 20.9% 8.6%

Profitability

14 metrics
MetricICLRMEDPCRL
Gross margin 23.4% 29.1% 32.7%
EBITDA margin 13.3% 22.4% 9.7%
Operating margin 8.7% 21.4% 2.3%
Pretax margin 6.3% 22.1% -4.6%
Net margin 5.4% 18.2% -6.0%
FCF margin 10.4% 23.5% 9.3%
Operating cash flow margin 12.5% 25.5% 14.6%
Return on equity 7.6% 101.7% -8.2%
Return on assets 4.3% 23.8% -3.1%
Return on invested capital 4.7% – 1.6%
Return on capital employed 5.3% 88.8% 1.4%
Asset turnover 0.5x 1.3x 0.5x
Cash conversion (OCF / net income) 2.3x 1.4x -2.4x
Stock comp / revenue 1.1% 0.8% 2.1%

Financial Health

11 metrics
MetricICLRMEDPCRL
Debt / assets 20.8% – 34.8%
Debt / equity 0.4x – 0.9x
Net debt / EBITDA 2.3x – 6.3x
Debt / FCF 3.9x – 7.1x
Liabilities / assets 43.8% 74.6% 62.2%
Equity / assets 56.2% 25.4% 37.8%
Interest coverage 3.4x – 0.8x
Current ratio 1.3x 0.8x 1.3x
Quick ratio 0.9x 0.8x 0.8x
Cash ratio 0.3x 0.5x 0.2x
Altman Z-score 2.28 8.36 3.18

Shareholder Returns

7 metrics
MetricICLRMEDPCRL
Dividend yield – – –
Net buyback yield 2.3% 1.3% 1.8%
Shareholder yield 2.3% 1.3% 1.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusICLRMEDPCRL
Forward P/E 21.0xFY2026 38.1xFY2026 34.5xFY2026
EPS, next fiscal year $10.25FY2026 $17.80FY2026 $10.90FY2026
EPS growth, next FY -18.2%FY2026 +16.5%FY2026 +6.0%FY2026
EPS growth, the year after +22.2% +6.2% +20.5%
Revenue, next fiscal year $8.52BFY2026 $2.94BFY2026 $3.82BFY2026
Revenue growth, next FY +3.2%FY2026 +16.4%FY2026 -4.9%FY2026
Revenue growth, the year after -3.2% +6.0% +0.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersICLRMEDPCRL
Held by institutions 100.0% 87.8% 100.0%
Institutions holding 423 694 571
Change in shares held, QoQ +5.5% +3.2% -0.7%
Institutions buying 234 279 271
Institutions selling 138 303 204
Buyers to sellers 1.70 0.92 1.33

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

ICLRMEDPCRL
ICLR 1.00 0.38 0.51
MEDP 0.38 1.00 0.58
CRL 0.51 0.58 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, ICLR, MEDP and CRL?

Medpace Holdings (MEDP) is the largest by market capitalisation: Icon (ICLR) $16.50B, Medpace Holdings (MEDP) $18.95B, Charles River Laboratories International (CRL) $17.94B.

Which stock is cheaper, ICLR, MEDP and CRL?

Medpace Holdings (MEDP) trades on the lowest price-to-earnings ratio (Icon (ICLR) 37.7x, Medpace Holdings (MEDP) 36.6x, Charles River Laboratories International (CRL) -75.7x). On next year's consensus earnings, Icon (ICLR) is cheapest (Icon (ICLR) 21.0x, Medpace Holdings (MEDP) 38.1x, Charles River Laboratories International (CRL) 34.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Medpace Holdings (MEDP) grew revenue fastest over the trailing twelve months: Icon (ICLR) +1.8%, Medpace Holdings (MEDP) +20.4%, Charles River Laboratories International (CRL) -0.7%.

Which company is more profitable?

Medpace Holdings (MEDP) has the highest net margin (Icon (ICLR) 5.4%, Medpace Holdings (MEDP) 18.2%, Charles River Laboratories International (CRL) -6.0%). On return on invested capital, Icon (ICLR) leads (Icon (ICLR) 4.7%, Charles River Laboratories International (CRL) 1.6%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Icon (ICLR) +29.8%, Medpace Holdings (MEDP) +15.9%, Charles River Laboratories International (CRL) +108.6%. Over five years, Medpace Holdings (MEDP) compounded fastest (Icon (ICLR) -5.6%/yr, Medpace Holdings (MEDP) +24.5%/yr, Charles River Laboratories International (CRL) -3.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Medpace Holdings (MEDP) has been the steadiest (Icon (ICLR) 75.0%, Medpace Holdings (MEDP) 45.6%, Charles River Laboratories International (CRL) 45.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, ICLR, MEDP and CRL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Medpace Holdings (MEDP) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.