HTFL vs LNTH vs PRE Stock Comparison

Heartflow, Lantheus Holdings and Prenetics Global Prices as of Oct 27, 2026 Peers: Industry group
1 more company in this comparison (CV) Create a free account to keep reading and compare up to 10 companies.
HTFL Heartflow, Inc.
$57.82 +17.6% 1M +50.8% 1Y
Market cap
$5.01B
P/E
–
Revenue (TTM)
$202.91M
Div. yield
–
Diagnostic Equipment Healthcare
LNTH Lantheus Holdings, Inc.
$100.15 +0.4% 1M +72.3% 1Y
Market cap
$6.54B
P/E
23.7x
Revenue (TTM)
$1.56B
Div. yield
–
Diagnostic Equipment Healthcare
6 wins
PRE Prenetics Global Ltd
$18.43 -19.8% 1M +40.9% 1Y
Market cap
$310.99M
P/E
–
Revenue (TTM)
$185.92M
Div. yield
–
Diagnostic Equipment Healthcare
1 win

Head to Head

7 decided of 12

Lantheus Holdings leads on 6 of the 12 questions below (Lantheus Holdings 6, Prenetics Global 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionHTFLLNTHPRELeader
Larger companyMarket capitalisation $5.01B $6.54B $310.99M LNTH
Cheaper on earningsLower P/E, profitable companies only -49.9x 23.7x -3.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 17.4x — –
Faster revenue growthRevenue growth, trailing twelve months +42.5% +2.3% +513.0% PRE
More profitableNet margin, trailing twelve months -49.4% 17.7% -38.2% LNTH
Better return on capitalReturn on invested capital — 12.5% — –
Less leveragedLower net debt / EBITDA — -0.1x — –
Higher dividend yieldTrailing dividend yield — — 0.00% –
Better 1-year returnPrice return, last 12 months +50.8% +72.3% +40.9% LNTH
Better 5-year returnAnnualised price return, 5 years — +34.4%/yr -30.7%/yr LNTH
Less volatileAnnualised volatility, 1 year 76.7% 32.3% 81.0% LNTH
Higher overall scoreMean of the five percentile scores vs peers 57/100 80/100 51/100 LNTH

Percentile Scorecard

HTFLLNTHPRE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisHTFLLNTHPRE
Valuation 9 #207 of 227 80 #46 of 227 35 #148 of 227
Growth 78 #49 of 219 63 #82 of 219 68 #70 of 219
Profitability 49 #106 of 206 94 #13 of 206 43 #118 of 206
Financial Health 92 #20 of 238 69 #74 of 238 57 #102 of 238
Shareholder Returns – 93 #11 of 134 –
Overall 57 80 51
  • HTFL ranked among 247 companies in Medical Devices and Diagnostics
  • LNTH ranked among 247 companies in Medical Devices and Diagnostics
  • PRE ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodHTFLLNTHPRESPY
1 month +17.6%+0.4%-19.8% -0.2%
3 months +125.9%-2.4%+0.9% +3.9%
6 months +89.3%+19.9%+0.3% +8.2%
Year to date +98.4%+50.5%+17.0% +12.9%
1 year +50.8%+72.3%+40.9% +12.3%
3 years —+49.9%+228.9% +87.4%
3 years, per year —+14.4%+48.8% +23.3%
5 years —+337.5%-84.0% +67.9%
5 years, per year —+34.4%-30.7% +10.9%
10 years —+1,092.3%— +261.1%
10 years, per year —+28.1%— +13.7%

Risk

MeasureHTFLLNTHPRESPY
Volatility, 1Y 76.7%32.3%81.0% 12.7%
Downside volatility, 1Y 77.5%27.5%74.2% 12.7%
Beta vs S&P 500, 1Y 1.900.591.52 1.00
Return / volatility, 1Y 0.662.240.50 0.97
Max drawdown, 5Y -48.7%-59.5%-97.6% -25.4%
From 52-week high 0.0%-9.7%-29.8% -1.2%
52-week high $57.82$110.94$26.25 $779.14
52-week low $20.49$50.69$11.79 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleHTFLLNTHPRE
P/E now vs peer median -49.9xmedian 29.6x 23.7xmedian 29.6x -3.6xmedian 29.6x
P/S now vs peer median 24.7xmedian 2.9x 4.2xmedian 2.9x 1.7xmedian 2.9x
EV/EBITDA now vs peer median —median 17.4x 16.5xmedian 17.4x -4.2xmedian 17.4x
P/FCF now vs peer median —median 22.3x 16.9xmedian 22.3x -6.0xmedian 22.3x
P/B now vs peer median 17.9xmedian 2.3x 5.0xmedian 2.3x 3.3xmedian 2.3x
PEG now vs peer median —median 1.04 0.22median 1.04 -0.07median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsHTFLLNTHPRE
Revenue $202.91M $1.56B $185.92M
Gross profit $160.45M $936.02M $88.89M
Operating income -$64.46M $302.34M -$61.83M
Net income -$100.19M $275.31M -$71.99M
Free cash flow – $387.83M -$51.49M
R&D $77.26M $173.09M $4.11M
EPS (diluted) $-1.16 $4.08 $-5.06
Cash & equivalents $34.36M $593.30M $59.05M
Total debt – $571.05M –
Shares (diluted) 86.40M 67.52M 14.05M
Enterprise value $4.77B $4.70B $174.72M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricHTFLLNTHPRE
P/E -49.9x 23.7x -3.6x
P/FCF – 16.9x -6.0x
P/Operating cash flow – 15.8x -6.0x
P/S 24.7x 4.2x 1.7x
P/B 17.9x 5.0x 3.3x
P/Tangible book 17.9x 10.5x 3.3x
EV/EBITDA – 16.5x -4.2x
EV/EBIT -74.0x 21.5x -4.1x
EV/Revenue 23.5x 4.2x 1.4x
EV/FCF – 16.8x -4.9x
EV/Operating cash flow – 15.8x -4.9x
PEG (3Y EPS CAGR) – 0.22 -0.07

Growth

14 metrics
MetricHTFLLNTHPRE
Revenue growth (1Y) 42.5% 2.3% 513.0%
Revenue CAGR (3Y) – 11.4% 115.5%
Gross profit growth (1Y) 48.8% -3.4% 413.6%
Gross profit CAGR (3Y) – 16.3% 127.9%
Operating income growth (1Y) -9.5% -30.9% -49.2%
Operating income CAGR (3Y) – 118.8% -1.9%
Net income growth (1Y) -18.3% 1.6% -60.1%
Net income CAGR (3Y) – 102.1% -16.5%
EPS growth (1Y) 91.4% 5.8% -28.5%
EPS CAGR (3Y) – 105.5% 52.8%
Operating cash flow growth (1Y) – -21.7% –
Operating cash flow CAGR (3Y) – 14.5% –
Free cash flow growth (1Y) – -10.1% –
Free cash flow CAGR (3Y) – 103.0% –

Profitability

14 metrics
MetricHTFLLNTHPRE
Gross margin 79.1% 60.1% 47.8%
EBITDA margin – 25.4% -32.6%
Operating margin -31.8% 19.4% -33.3%
Pretax margin -49.4% 23.3% -24.2%
Net margin -49.4% 17.7% -38.2%
FCF margin – 24.9% -27.7%
Operating cash flow margin – 26.5% -27.7%
Return on equity -34.5% 21.8% -67.3%
Return on assets -28.5% 11.6% -43.8%
Return on invested capital – 12.5% –
Return on capital employed -20.9% 14.8% -48.3%
Asset turnover 0.6x 0.7x 1.1x
Cash conversion (OCF / net income) – 1.5x 0.7x
Stock comp / revenue 9.6% 5.0% 3.4%

Financial Health

11 metrics
MetricHTFLLNTHPRE
Debt / assets – 23.6% –
Debt / equity – 0.4x –
Net debt / EBITDA – -0.1x –
Debt / FCF – 1.5x –
Liabilities / assets 18.8% 45.7% 39.5%
Equity / assets 81.2% 54.3% 60.5%
Interest coverage – 15.3x –
Current ratio 5.1x 3.1x 4.0x
Quick ratio 6.6x 2.8x 1.8x
Cash ratio 5.6x 1.8x 1.6x
Altman Z-score 42.47 5.46 –

Shareholder Returns

7 metrics
MetricHTFLLNTHPRE
Dividend yield – – –
Net buyback yield – 2.9% –
Shareholder yield – 2.9% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusHTFLLNTHPRE
Forward P/E – 17.4xFY2026 –
EPS, next fiscal year $-0.43FY2026 $5.76FY2026 $-3.42FY2026
EPS growth, next FY – -5.3%FY2026 –
EPS growth, the year after – +4.2% –
Revenue, next fiscal year $261.38MFY2026 $1.57BFY2026 $234.43MFY2026
Revenue growth, next FY +48.5%FY2026 +1.8%FY2026 +153.7%FY2026
Revenue growth, the year after +20.6% +12.7% +65.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersHTFLLNTHPRE
Held by institutions 100.0% 100.0% 0.9%
Institutions holding 192 465 1
Change in shares held, QoQ +133.0% +3.4% –
Institutions buying 140 248 0
Institutions selling 38 142 0
Buyers to sellers 3.68 1.75 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

HTFLLNTHPRE
HTFL 1.00 0.14 0.18
LNTH 0.14 1.00 0.09
PRE 0.18 0.09 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, HTFL, LNTH and PRE?

Lantheus Holdings (LNTH) is the largest by market capitalisation: Heartflow (HTFL) $5.01B, Lantheus Holdings (LNTH) $6.54B, Prenetics Global (PRE) $310.99M.

Which company is growing faster?

Prenetics Global (PRE) grew revenue fastest over the trailing twelve months: Heartflow (HTFL) +42.5%, Lantheus Holdings (LNTH) +2.3%, Prenetics Global (PRE) +513.0%.

Which company is more profitable?

Lantheus Holdings (LNTH) has the highest net margin (Heartflow (HTFL) -49.4%, Lantheus Holdings (LNTH) 17.7%, Prenetics Global (PRE) -38.2%).

Which stock has performed better?

Over the past year Lantheus Holdings (LNTH) returned the most: Heartflow (HTFL) +50.8%, Lantheus Holdings (LNTH) +72.3%, Prenetics Global (PRE) +40.9%. Over five years, Lantheus Holdings (LNTH) compounded fastest (Lantheus Holdings (LNTH) +34.4%/yr, Prenetics Global (PRE) -30.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Lantheus Holdings (LNTH) has been the steadiest (Heartflow (HTFL) 76.7%, Lantheus Holdings (LNTH) 32.3%, Prenetics Global (PRE) 81.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, HTFL, LNTH and PRE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Lantheus Holdings (LNTH) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.