GSK vs AZN vs PFE Stock Comparison

Gsk, Astrazeneca and Pfizer Prices as of Oct 28, 2026 Peers: Industry group
GSK GSK plc
$48.76 -1.9% 1M +11.6% 1Y
Market cap
$105.21B
P/E
7.8x
Revenue (TTM)
$76.96B
Div. yield
3.69%
Pharmaceuticals Healthcare
4 wins
AZN Astrazeneca Plc
$169.54 +1.9% 1M +2.6% 1Y
Market cap
$262.79B
P/E
25.2x
Revenue (TTM)
$58.67B
Div. yield
1.41%
Pharmaceuticals Healthcare
5 wins
PFE Pfizer Inc
$29.48 +2.6% 1M +20.3% 1Y
Market cap
$168.03B
P/E
38.8x
Revenue (TTM)
$63.70B
Div. yield
5.83%
Pharmaceuticals Healthcare
3 wins

Head to Head

12 decided of 12

Astrazeneca leads on 5 of the 12 questions below (Astrazeneca 5, Gsk 4, Pfizer 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGSKAZNPFELeader
Larger companyMarket capitalisation $105.21B $262.79B $168.03B AZN
Cheaper on earningsLower P/E, profitable companies only 7.8x 25.2x 38.8x GSK
Cheaper on forward earningsLower price / next fiscal year consensus EPS 9.6x 17.0x 10.3x GSK
Faster revenue growthRevenue growth, trailing twelve months +82.9% +9.4% -0.2% GSK
More profitableNet margin, trailing twelve months 16.4% 17.8% 6.8% AZN
Better return on capitalReturn on invested capital — 23.3% 13.4% AZN
Less leveragedLower net debt / EBITDA — 1.4x 1.9x AZN
Higher dividend yieldTrailing dividend yield 3.69% 1.41% 5.83% PFE
Better 1-year returnPrice return, last 12 months +11.6% +2.6% +20.3% PFE
Better 5-year returnAnnualised price return, 5 years +2.9%/yr +6.3%/yr -7.6%/yr AZN
Less volatileAnnualised volatility, 1 year 26.5% 27.3% 21.6% PFE
Higher overall scoreMean of the five percentile scores vs peers 80/100 71/100 65/100 GSK

Percentile Scorecard

GSKAZNPFE

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGSKAZNPFE
Valuation 91 #56 of 625 85 #92 of 625 95 #30 of 625
Growth 75 #151 of 602 70 #183 of 602 23 #462 of 602
Profitability 96 #25 of 549 94 #34 of 549 92 #45 of 549
Financial Health 52 #313 of 654 36 #418 of 654 23 #504 of 654
Shareholder Returns 85 #56 of 367 70 #112 of 367 92 #30 of 367
Overall 80 71 65
  • GSK ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AZN ranked among 672 companies in Pharmaceuticals and Biotechnology
  • PFE ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGSKAZNPFESPY
1 month -1.9%+1.9%+2.6% +0.9%
3 months -8.4%-2.2%+17.2% +5.9%
6 months -5.1%-8.5%+12.3% +8.5%
Year to date -0.6%-7.8%+18.4% +13.3%
1 year +11.6%+2.6%+20.3% +12.4%
3 years +41.1%+37.0%-2.1% +88.1%
3 years, per year +12.2%+11.1%-0.7% +23.5%
5 years +15.2%+35.9%-32.6% +68.2%
5 years, per year +2.9%+6.3%-7.6% +11.0%
10 years +21.5%+196.4%-7.7% +263.4%
10 years, per year +2.0%+11.5%-0.8% +13.8%

Risk

MeasureGSKAZNPFESPY
Volatility, 1Y 26.5%27.3%21.6% 12.7%
Downside volatility, 1Y 24.2%27.1%21.1% 12.7%
Beta vs S&P 500, 1Y 0.210.210.23 1.00
Return / volatility, 1Y 0.440.100.94 0.98
Max drawdown, 5Y -38.8%-27.9%-64.8% -25.4%
From 52-week high -20.3%-19.1%-3.1% -0.9%
52-week high $61.18$209.48$30.41 $779.14
52-week low $43.70$155.60$23.67 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGSKAZNPFE
P/E now vs peer median 7.8xmedian 17.4x 25.2xmedian 17.4x 38.8xmedian 17.4x
P/S now vs peer median 1.4xmedian 9.1x 4.5xmedian 9.1x 2.6xmedian 9.1x
EV/EBITDA now vs peer median —median 17.1x 14.3xmedian 17.1x 8.1xmedian 17.1x
P/FCF now vs peer median —median 19.0x 24.6xmedian 19.0x 15.3xmedian 19.0x
P/B now vs peer median 4.3xmedian 2.2x 5.2xmedian 2.2x 2.0xmedian 2.2x
PEG now vs peer median 0.42median 0.34 1.31median 0.34 -0.94median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGSKAZNPFE
Revenue $76.96B $58.67B $63.70B
Gross profit $56.19B $50.25B $46.61B
Operating income $17.15B $13.97B $20.39B
Net income $2.75B $10.45B $4.36B
Free cash flow – $10.67B $10.99B
R&D $19.61B $15.07B $11.05B
EPS (diluted) $6.12 $6.69 $0.76
Cash & equivalents $3.88B $4.90B $976.00M
Total debt -$31.50B $32.35B $63.19B
Shares (diluted) 2.06B 1.56B 5.70B
Enterprise value $87.53B $236.55B $114.97B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGSKAZNPFE
P/E 7.8x 25.2x 38.8x
P/FCF – 24.6x 15.3x
P/Operating cash flow – 19.2x 12.5x
P/S 1.4x 4.5x 2.6x
P/B 4.3x 5.2x 2.0x
P/Tangible book -11.7x 20.8x 4.4x
EV/EBITDA – 14.3x 8.1x
EV/EBIT 4.1x 20.8x 10.8x
EV/Revenue 0.9x 4.9x 3.4x
EV/FCF – 27.2x 20.0x
EV/Operating cash flow – 21.2x 16.4x
PEG (3Y EPS CAGR) 0.42 1.31 -0.94

Growth

14 metrics
MetricGSKAZNPFE
Revenue growth (1Y) 82.9% 9.4% -0.2%
Revenue CAGR (3Y) 28.3% 10.6% -7.0%
Gross profit growth (1Y) 84.8% 9.3% 1.2%
Gross profit CAGR (3Y) 29.1% 13.1% -5.6%
Operating income growth (1Y) 73.5% 23.4% 1.5%
Operating income CAGR (3Y) 20.2% 23.9% -9.9%
Net income growth (1Y) -70.9% 25.9% -59.6%
Net income CAGR (3Y) -48.4% 19.2% -41.3%
EPS growth (1Y) 75.6% 26.0% -59.7%
EPS CAGR (3Y) 18.8% 19.2% -41.3%
Operating cash flow growth (1Y) – 2.3% -11.8%
Operating cash flow CAGR (3Y) – 13.7% -2.7%
Free cash flow growth (1Y) – -4.5% -11.7%
Free cash flow CAGR (3Y) – 8.5% 1.0%

Profitability

14 metrics
MetricGSKAZNPFE
Gross margin 73.0% 85.6% 73.2%
EBITDA margin – 34.6% 42.4%
Operating margin 22.3% 23.8% 32.0%
Pretax margin 20.5% 21.5% 6.6%
Net margin 16.4% 17.8% 6.8%
FCF margin – 18.2% 17.2%
Operating cash flow margin – 23.3% 21.0%
Return on equity 71.9% 21.4% 5.0%
Return on assets 19.2% 9.1% 2.1%
Return on invested capital – 23.3% 13.4%
Return on capital employed 14.8% 16.8% 11.9%
Asset turnover 0.9x 0.5x 0.3x
Cash conversion (OCF / net income) – 1.3x 3.1x
Stock comp / revenue – – 1.5%

Financial Health

11 metrics
MetricGSKAZNPFE
Debt / assets -33.2% 27.9% 31.4%
Debt / equity -1.3x 0.6x 0.7x
Net debt / EBITDA – 1.4x 1.9x
Debt / FCF – 3.0x 5.8x
Liabilities / assets 74.4% 56.5% 57.5%
Equity / assets 25.6% 43.5% 42.5%
Interest coverage 10.1x 15.9x –
Current ratio -0.9x 0.9x 1.3x
Quick ratio -0.5x 0.7x 0.7x
Cash ratio -0.1x 0.2x 0.4x
Altman Z-score 3.19 3.43 2.36

Shareholder Returns

7 metrics
MetricGSKAZNPFE
Dividend yield 3.7% 1.4% 5.8%
Net buyback yield – 0.0% –
Shareholder yield 3.7% 1.4% 5.8%
Payout ratio (earnings) – – 224.5%
Payout ratio (FCF) – – 89.1%
Dividend growth (1Y) – – 1.5%
Dividend CAGR (3Y) – – 2.4%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGSKAZNPFE
Forward P/E 9.6xFY2026 17.0xFY2026 10.3xFY2026
EPS, next fiscal year $5.07FY2026 $10.00FY2026 $2.85FY2026
EPS growth, next FY +7.9%FY2026 +9.2%FY2026 -11.5%FY2026
EPS growth, the year after +4.7% +6.1% -4.6%
Revenue, next fiscal year $48.12BFY2026 $59.02BFY2026 $60.59BFY2026
Revenue growth, next FY +7.8%FY2026 +0.5%FY2026 -3.2%FY2026
Revenue growth, the year after +1.1% +8.0% +3.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGSKAZNPFE
Held by institutions 16.0% 52.1% 66.9%
Institutions holding 1,037 1,496 2,836
Change in shares held, QoQ -7.4% +7.8% +2.0%
Institutions buying 484 808 1,325
Institutions selling 334 468 1,204
Buyers to sellers 1.45 1.73 1.10

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GSKAZNPFE
GSK 1.00 0.60 0.49
AZN 0.60 1.00 0.42
PFE 0.49 0.42 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, GSK, AZN and PFE?

Astrazeneca (AZN) is the largest by market capitalisation: Gsk (GSK) $105.21B, Astrazeneca (AZN) $262.79B, Pfizer (PFE) $168.03B.

Which stock is cheaper, GSK, AZN and PFE?

Gsk (GSK) trades on the lowest price-to-earnings ratio (Gsk (GSK) 7.8x, Astrazeneca (AZN) 25.2x, Pfizer (PFE) 38.8x). On next year's consensus earnings, Gsk (GSK) is cheapest (Gsk (GSK) 9.6x, Astrazeneca (AZN) 17.0x, Pfizer (PFE) 10.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Gsk (GSK) grew revenue fastest over the trailing twelve months: Gsk (GSK) +82.9%, Astrazeneca (AZN) +9.4%, Pfizer (PFE) -0.2%.

Which company is more profitable?

Astrazeneca (AZN) has the highest net margin (Gsk (GSK) 16.4%, Astrazeneca (AZN) 17.8%, Pfizer (PFE) 6.8%). On return on invested capital, Astrazeneca (AZN) leads (Astrazeneca (AZN) 23.3%, Pfizer (PFE) 13.4%).

Which stock has performed better?

Over the past year Pfizer (PFE) returned the most: Gsk (GSK) +11.6%, Astrazeneca (AZN) +2.6%, Pfizer (PFE) +20.3%. Over five years, Astrazeneca (AZN) compounded fastest (Gsk (GSK) +2.9%/yr, Astrazeneca (AZN) +6.3%/yr, Pfizer (PFE) -7.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Pfizer (PFE) has the highest dividend yield: Gsk (GSK) 3.69%, Astrazeneca (AZN) 1.41%, Pfizer (PFE) 5.83%.

Which stock is riskier?

By one-year price volatility, Pfizer (PFE) has been the steadiest (Gsk (GSK) 26.5%, Astrazeneca (AZN) 27.3%, Pfizer (PFE) 21.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GSK, AZN and PFE?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Astrazeneca (AZN) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.