GRFS vs QGEN vs REGN Stock Comparison

Grifols, Qiagen and Regeneron Pharmaceuticals Prices as of Nov 4, 2026 Peers: Industry group
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GRFS Grifols SA
$8.60 +16.1% 1M -6.7% 1Y
Market cap
$5.83B
P/E
12.9x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
3 wins
QGEN Qiagen N.V.
$50.82 +11.0% 1M +9.3% 1Y
Market cap
$11.03B
P/E
27.0x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 8 of the 12 questions below (Regeneron Pharmaceuticals 8, Grifols 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSQGENREGNLeader
Larger companyMarket capitalisation $5.83B $11.03B $95.94B REGN
Cheaper on earningsLower P/E, profitable companies only 12.9x 27.0x 19.9x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 9.1x 21.6x 16.3x GRFS
Faster revenue growthRevenue growth, trailing twelve months — +3.0% +18.6% REGN
More profitableNet margin, trailing twelve months — 19.5% 28.5% REGN
Better return on capitalReturn on invested capital — 7.9% 11.9% REGN
Less leveragedLower net debt / EBITDA — 1.3x -1.4x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -6.7% +9.3% +48.2% REGN
Better 5-year returnAnnualised price return, 5 years -6.8%/yr -3.4%/yr +8.8%/yr REGN
Less volatileAnnualised volatility, 1 year 32.6% 35.4% 33.7% GRFS
Higher overall scoreMean of the five percentile scores vs peers 56/100 71/100 74/100 REGN

Percentile Scorecard

GRFSQGENREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSQGENREGN
Valuation 99 #9 of 634 75 #58 of 229 90 #67 of 634
Growth – 30 #156 of 221 52 #292 of 607
Profitability – 93 #16 of 209 91 #50 of 557
Financial Health 14 #566 of 654 64 #86 of 240 74 #170 of 654
Shareholder Returns 57 #173 of 400 94 #10 of 146 63 #147 of 400
Overall 56 71 74
  • GRFS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • QGEN ranked among 248 companies in Medical Devices and Diagnostics
  • REGN ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSQGENREGNSPY
1 month +16.1%+11.0%+28.0% -1.0%
3 months +8.4%+21.2%+21.1% -0.4%
6 months +2.3%+47.6%+29.1% +4.5%
Year to date -8.0%+7.4%+20.6% +12.4%
1 year -6.7%+9.3%+48.2% +13.6%
3 years -7.6%+16.1%+13.9% +76.4%
3 years, per year -2.6%+5.1%+4.4% +20.8%
5 years -29.6%-16.1%+52.2% +63.7%
5 years, per year -6.8%-3.4%+8.8% +10.4%
10 years -41.1%+64.8%+172.6% +267.7%
10 years, per year -5.2%+5.1%+10.6% +13.9%

Risk

MeasureGRFSQGENREGNSPY
Volatility, 1Y 32.6%35.4%33.7% 12.8%
Downside volatility, 1Y 34.1%30.1%30.7% 12.7%
Beta vs S&P 500, 1Y 0.880.430.23 1.00
Return / volatility, 1Y -0.210.261.43 1.06
Max drawdown, 5Y -58.8%-48.2%-59.8% -25.4%
From 52-week high -11.5%-8.7%-4.4% -1.6%
52-week high $9.72$55.66$973.36 $779.14
52-week low $7.02$32.63$600.66 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSQGENREGN
P/E now vs peer median 12.9xmedian 18.0x 27.0xmedian 28.5x 19.6xmedian 18.0x
P/S now vs peer median 0.7xmedian 9.1x 5.2xmedian 2.9x 5.6xmedian 9.1x
EV/EBITDA now vs peer median —median 16.2x 18.2xmedian 18.5x 16.2xmedian 16.2x
P/FCF now vs peer median 8.3xmedian 21.7x 11.1xmedian 26.7x 24.7xmedian 21.7x
P/B now vs peer median 0.7xmedian 2.2x 3.3xmedian 2.3x 2.8xmedian 2.2x
PEG now vs peer median —median 0.38 6.60median 0.93 2.18median 0.38

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSQGENREGN
Revenue – $2.10B $16.90B
Gross profit – $1.31B $14.49B
Operating income – $445.43M $4.86B
Net income – $409.32M $4.82B
Free cash flow – $991.33M $3.83B
R&D – $194.67M $6.60B
EPS (diluted) – $1.87 $45.62
Cash & equivalents $969.15M $768.50M $3.66B
Total debt $11.33B $1.64B $1.99B
Shares (diluted) 681.57M 218.88M 105.60M
Enterprise value $2.17B $6.80B $61.29B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSQGENREGN
P/E 12.9x 27.0x 19.6x
P/FCF 8.3x 11.1x 24.7x
P/Operating cash flow – 16.8x 19.5x
P/S 0.7x 5.2x 5.6x
P/B 0.7x 3.3x 2.8x
P/Tangible book 1.0x 3.7x 2.9x
EV/EBITDA – 18.2x 16.2x
EV/EBIT – 26.7x 18.0x
EV/Revenue – 5.7x 5.2x
EV/FCF – 12.0x 22.8x
EV/Operating cash flow – 18.1x 18.0x
PEG (3Y EPS CAGR) – 6.60 2.18

Growth

14 metrics
MetricGRFSQGENREGN
Revenue growth (1Y) – 3.0% 18.6%
Revenue CAGR (3Y) – 2.0% 8.9%
Gross profit growth (1Y) – 1.7% 19.1%
Gross profit CAGR (3Y) – 1.3% 8.8%
Operating income growth (1Y) – -4.9% 31.9%
Operating income CAGR (3Y) – 3.3% 4.8%
Net income growth (1Y) – 143.9% 5.2%
Net income CAGR (3Y) – 6.7% 6.5%
EPS growth (1Y) – 6.6% 6.8%
EPS CAGR (3Y) – 4.1% 9.0%
Operating cash flow growth (1Y) – -3.0% -4.4%
Operating cash flow CAGR (3Y) – 8.0% -2.5%
Free cash flow growth (1Y) – 2.3% -9.4%
Free cash flow CAGR (3Y) – 10.5% -6.0%

Profitability

14 metrics
MetricGRFSQGENREGN
Gross margin – 62.2% 85.8%
EBITDA margin – 31.0% 31.8%
Operating margin – 21.2% 28.8%
Pretax margin – 22.0% 33.7%
Net margin – 19.5% 28.5%
FCF margin – 47.2% 22.6%
Operating cash flow margin – 31.2% 28.7%
Return on equity – 12.2% 14.8%
Return on assets – 7.0% 11.2%
Return on invested capital – 7.9% 11.9%
Return on capital employed – 8.5% 13.2%
Asset turnover – 0.4x 0.4x
Cash conversion (OCF / net income) – 1.6x 1.0x
Stock comp / revenue – 2.1% 6.0%

Financial Health

11 metrics
MetricGRFSQGENREGN
Debt / assets 48.9% 27.9% 4.5%
Debt / equity 1.3x 0.5x 0.1x
Net debt / EBITDA – 1.3x -1.4x
Debt / FCF – 1.7x 0.5x
Liabilities / assets 61.4% 43.0% 24.6%
Equity / assets 38.6% 57.0% 75.4%
Interest coverage – 11.3x 104.2x
Current ratio 2.5x 2.8x 3.4x
Quick ratio 0.8x 2.0x 2.7x
Cash ratio 0.4x 1.4x 1.5x
Altman Z-score – 4.11 7.59

Shareholder Returns

7 metrics
MetricGRFSQGENREGN
Dividend yield 1.3% 5.2% 0.4%
Net buyback yield – 0.6% 2.1%
Shareholder yield 1.3% 5.8% 2.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSQGENREGN
Forward P/E 9.1xFY2026 21.6xFY2026 16.3xFY2026
EPS, next fiscal year $0.94FY2026 $2.35FY2026 $57.08FY2026
EPS growth, next FY +10.6%FY2026 -1.3%FY2026 +28.8%FY2026
EPS growth, the year after +26.6% +17.4% +15.5%
Revenue, next fiscal year $8.88BFY2026 $2.25BFY2026 $17.05BFY2026
Revenue growth, next FY +0.0%FY2026 +7.8%FY2026 +18.9%FY2026
Revenue growth, the year after +10.3% -2.8% +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSQGENREGN
Held by institutions 21.0% 67.3% 66.2%
Institutions holding 168 338 1,329
Change in shares held, QoQ -0.5% +16.5% +3.8%
Institutions buying 75 216 607
Institutions selling 65 86 534
Buyers to sellers 1.15 2.51 1.14

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSQGENREGN
GRFS 1.00 0.17 0.30
QGEN 0.17 1.00 0.19
REGN 0.30 0.19 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, QGEN and REGN?

Regeneron Pharmaceuticals (REGN) is the largest by market capitalisation: Grifols (GRFS) $5.83B, Qiagen (QGEN) $11.03B, Regeneron Pharmaceuticals (REGN) $95.94B.

Which stock is cheaper, GRFS, QGEN and REGN?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.9x, Qiagen (QGEN) 27.0x, Regeneron Pharmaceuticals (REGN) 19.9x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 9.1x, Qiagen (QGEN) 21.6x, Regeneron Pharmaceuticals (REGN) 16.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: Qiagen (QGEN) +3.0%, Regeneron Pharmaceuticals (REGN) +18.6%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Qiagen (QGEN) 19.5%, Regeneron Pharmaceuticals (REGN) 28.5%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Qiagen (QGEN) 7.9%, Regeneron Pharmaceuticals (REGN) 11.9%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: Grifols (GRFS) -6.7%, Qiagen (QGEN) +9.3%, Regeneron Pharmaceuticals (REGN) +48.2%. Over five years, Regeneron Pharmaceuticals (REGN) compounded fastest (Grifols (GRFS) -6.8%/yr, Qiagen (QGEN) -3.4%/yr, Regeneron Pharmaceuticals (REGN) +8.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Grifols (GRFS) has been the steadiest (Grifols (GRFS) 32.6%, Qiagen (QGEN) 35.4%, Regeneron Pharmaceuticals (REGN) 33.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, QGEN and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.