GRFS vs QGEN vs AMGN Stock Comparison

Grifols, Qiagen and Amgen Prices as of Oct 27, 2026 Peers: Industry group
GRFS Grifols SA
$8.10 +10.2% 1M -13.6% 1Y
Market cap
$5.54B
P/E
12.1x
Revenue (TTM)
—
Div. yield
–
Biotechnology Healthcare
2 wins
QGEN Qiagen N.V.
$50.18 +13.6% 1M -1.5% 1Y
Market cap
$10.92B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
–
Life Sciences Tools Healthcare
2 wins
AMGN Amgen Inc
$447.95 +8.0% 1M +53.9% 1Y
Market cap
$243.27B
P/E
27.8x
Revenue (TTM)
$38.10B
Div. yield
0.02%
Biotechnology Healthcare
7 wins

Head to Head

11 decided of 12

Amgen leads on 7 of the 12 questions below (Amgen 7, Grifols 2, Qiagen 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSQGENAMGNLeader
Larger companyMarket capitalisation $5.54B $10.92B $243.27B AMGN
Cheaper on earningsLower P/E, profitable companies only 12.1x 26.7x 27.8x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 8.6x 21.4x 20.5x GRFS
Faster revenue growthRevenue growth, trailing twelve months — +3.0% +9.1% AMGN
More profitableNet margin, trailing twelve months — 19.5% 23.0% AMGN
Better return on capitalReturn on invested capital — 7.9% 14.3% AMGN
Less leveragedLower net debt / EBITDA — 1.3x 2.7x QGEN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.02% –
Better 1-year returnPrice return, last 12 months -13.6% -1.5% +53.9% AMGN
Better 5-year returnAnnualised price return, 5 years -9.4%/yr -3.8%/yr +16.7%/yr AMGN
Less volatileAnnualised volatility, 1 year 32.4% 35.8% 29.6% AMGN
Higher overall scoreMean of the five percentile scores vs peers 56/100 71/100 66/100 QGEN

Percentile Scorecard

GRFSQGENAMGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSQGENAMGN
Valuation 99 #7 of 625 76 #56 of 227 86 #90 of 625
Growth – 31 #151 of 219 62 #231 of 602
Profitability – 93 #16 of 206 95 #31 of 551
Financial Health 14 #564 of 656 63 #89 of 238 22 #510 of 656
Shareholder Returns 56 #161 of 365 94 #9 of 134 68 #117 of 365
Overall 56 71 66
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSQGENAMGNSPY
1 month +10.2%+13.6%+8.0% -0.2%
3 months +1.2%+18.8%+14.0% +3.9%
6 months +0.4%+47.5%+31.9% +8.2%
Year to date -13.4%+6.0%+36.9% +12.9%
1 year -13.6%-1.5%+53.9% +12.3%
3 years +3.3%+24.5%+71.3% +87.4%
3 years, per year +1.1%+7.6%+19.7% +23.3%
5 years -39.0%-17.4%+116.2% +67.9%
5 years, per year -9.4%-3.8%+16.7% +10.9%
10 years -44.7%+74.3%+179.0% +261.1%
10 years, per year -5.8%+5.7%+10.8% +13.7%

Risk

MeasureGRFSQGENAMGNSPY
Volatility, 1Y 32.4%35.8%29.6% 12.7%
Downside volatility, 1Y 34.1%30.4%27.9% 12.7%
Beta vs S&P 500, 1Y 0.950.470.46 1.00
Return / volatility, 1Y -0.42-0.041.82 0.97
Max drawdown, 5Y -58.8%-48.2%-26.7% -25.4%
From 52-week high -16.7%-9.8%0.0% -1.2%
52-week high $9.72$55.66$447.95 $779.14
52-week low $7.02$32.63$291.16 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSQGENAMGN
P/E now vs peer median 12.1xmedian 17.2x 26.6xmedian 29.6x 27.7xmedian 17.2x
P/S now vs peer median 0.6xmedian 9.0x 5.2xmedian 2.9x 6.4xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x 18.0xmedian 17.4x 17.7xmedian 16.3x
P/FCF now vs peer median 7.8xmedian 18.7x 11.0xmedian 22.3x 23.8xmedian 18.7x
P/B now vs peer median 0.6xmedian 2.2x 3.2xmedian 2.3x 20.7xmedian 2.2x
PEG now vs peer median —median 0.33 3.60median 1.04 10.44median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSQGENAMGN
Revenue – $2.10B $38.10B
Gross profit – $1.31B $26.48B
Operating income – $445.43M $11.43B
Net income – $409.32M $8.74B
Free cash flow – $991.33M $10.18B
R&D – $194.67M $7.63B
EPS (diluted) – $1.87 $16.07
Cash & equivalents $969.15M $768.50M $13.99B
Total debt $44.00B $6.86B $57.30B
Shares (diluted) 681.57M 218.88M 544.00M
Enterprise value $1.88B $6.69B $198.67B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSQGENAMGN
P/E 12.1x 26.6x 27.7x
P/FCF 7.8x 11.0x 23.8x
P/Operating cash flow – 16.6x 19.4x
P/S 0.6x 5.2x 6.4x
P/B 0.6x 3.2x 20.7x
P/Tangible book 1.0x 3.6x -27.5x
EV/EBITDA – 18.0x 17.7x
EV/EBIT – 26.3x 25.0x
EV/Revenue – 5.6x 7.5x
EV/FCF – 11.8x 28.1x
EV/Operating cash flow – 17.9x 22.9x
PEG (3Y EPS CAGR) – 3.60 10.44

Growth

14 metrics
MetricGRFSQGENAMGN
Revenue growth (1Y) – 3.0% 9.1%
Revenue CAGR (3Y) – 2.0% 12.7%
Gross profit growth (1Y) – 1.7% 17.6%
Gross profit CAGR (3Y) – 1.3% 10.3%
Operating income growth (1Y) – -4.9% 39.5%
Operating income CAGR (3Y) – 3.3% 6.4%
Net income growth (1Y) – 143.9% 32.1%
Net income CAGR (3Y) – 6.7% 3.1%
EPS growth (1Y) – 12.5% 31.4%
EPS CAGR (3Y) – 7.4% 2.7%
Operating cash flow growth (1Y) – -3.0% 3.9%
Operating cash flow CAGR (3Y) – 8.0% 4.9%
Free cash flow growth (1Y) – 2.3% -4.1%
Free cash flow CAGR (3Y) – 10.5% 1.7%

Profitability

14 metrics
MetricGRFSQGENAMGN
Gross margin – 62.2% 69.5%
EBITDA margin – 31.0% 42.2%
Operating margin – 21.2% 30.0%
Pretax margin – 22.0% 27.0%
Net margin – 19.5% 23.0%
FCF margin – 47.2% 26.7%
Operating cash flow margin – 31.2% 32.8%
Return on equity – 12.2% 83.8%
Return on assets – 7.0% 9.3%
Return on invested capital – 7.9% 14.3%
Return on capital employed – 8.5% 16.7%
Asset turnover – 0.4x 0.4x
Cash conversion (OCF / net income) – 1.6x 1.4x
Stock comp / revenue – 2.1% 1.3%

Financial Health

11 metrics
MetricGRFSQGENAMGN
Debt / assets 48.9% 27.9% 59.9%
Debt / equity 1.3x 0.5x 4.9x
Net debt / EBITDA – 1.3x 2.7x
Debt / FCF – 1.7x 5.6x
Liabilities / assets 61.4% 43.0% 87.8%
Equity / assets 38.6% 57.0% 12.2%
Interest coverage – 11.3x 4.3x
Current ratio 2.5x 2.8x 1.4x
Quick ratio 0.8x 2.0x 0.9x
Cash ratio 0.4x 1.4x 0.5x
Altman Z-score – 4.07 2.32

Shareholder Returns

7 metrics
MetricGRFSQGENAMGN
Dividend yield 1.4% 5.3% 2.2%
Net buyback yield – 0.6% –
Shareholder yield 1.4% 5.8% 2.2%
Payout ratio (earnings) – – 60.4%
Payout ratio (FCF) – – 51.9%
Dividend growth (1Y) – – 6.3%
Dividend CAGR (3Y) – – 6.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSQGENAMGN
Forward P/E 8.6xFY2026 21.4xFY2026 20.5xFY2026
EPS, next fiscal year $0.94FY2026 $2.35FY2026 $21.81FY2026
EPS growth, next FY +10.6%FY2026 -1.3%FY2026 -0.1%FY2026
EPS growth, the year after +26.6% +17.4% +7.2%
Revenue, next fiscal year $8.88BFY2026 $2.25BFY2026 $41.51BFY2026
Revenue growth, next FY +0.0%FY2026 +7.8%FY2026 +12.9%FY2026
Revenue growth, the year after +10.3% -2.8% +2.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSQGENAMGN
Held by institutions 21.0% 0.0% 82.7%
Institutions holding 166 1 3,159
Change in shares held, QoQ -0.5% – +4.5%
Institutions buying 73 0 1,451
Institutions selling 65 0 1,217
Buyers to sellers 1.12 – 1.19

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSQGENAMGN
GRFS 1.00 0.18 0.24
QGEN 0.18 1.00 0.17
AMGN 0.24 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, QGEN and AMGN?

Amgen (AMGN) is the largest by market capitalisation: Grifols (GRFS) $5.54B, Qiagen (QGEN) $10.92B, Amgen (AMGN) $243.27B.

Which stock is cheaper, GRFS, QGEN and AMGN?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.1x, Qiagen (QGEN) 26.7x, Amgen (AMGN) 27.8x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 8.6x, Qiagen (QGEN) 21.4x, Amgen (AMGN) 20.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Amgen (AMGN) grew revenue fastest over the trailing twelve months: Qiagen (QGEN) +3.0%, Amgen (AMGN) +9.1%.

Which company is more profitable?

Amgen (AMGN) has the highest net margin (Qiagen (QGEN) 19.5%, Amgen (AMGN) 23.0%). On return on invested capital, Amgen (AMGN) leads (Qiagen (QGEN) 7.9%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Amgen (AMGN) returned the most: Grifols (GRFS) -13.6%, Qiagen (QGEN) -1.5%, Amgen (AMGN) +53.9%. Over five years, Amgen (AMGN) compounded fastest (Grifols (GRFS) -9.4%/yr, Qiagen (QGEN) -3.8%/yr, Amgen (AMGN) +16.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Grifols (GRFS) 0.00%, Qiagen (QGEN) 0.00%, Amgen (AMGN) 0.02%. Grifols (GRFS) and Qiagen (QGEN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Grifols (GRFS) 32.4%, Qiagen (QGEN) 35.8%, Amgen (AMGN) 29.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, QGEN and AMGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.