GRFS vs QGEN vs ALNY Stock Comparison

Grifols, Qiagen and Alnylam Pharmaceuticals Prices as of Oct 29, 2026 Peers: Industry group
GRFS Grifols SA
$8.04 +10.1% 1M -14.4% 1Y
Market cap
$5.47B
P/E
12.0x
Revenue (TTM)
—
Div. yield
1.37%
Biotechnology Healthcare
3 wins
QGEN Qiagen N.V.
$50.38 +13.5% 1M +1.4% 1Y
Market cap
$10.93B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
5.24%
Life Sciences Tools Healthcare
3 wins

Head to Head

9 decided of 12

Alnylam Pharmaceuticals leads on 3 of the 12 questions below (Alnylam Pharmaceuticals 3, Grifols 3, Qiagen 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSQGENALNYLeader
Larger companyMarket capitalisation $5.47B $10.93B $23.27B ALNY
Cheaper on earningsLower P/E, profitable companies only 12.0x 26.7x 46.3x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 8.6x 21.4x 25.7x GRFS
Faster revenue growthRevenue growth, trailing twelve months — +3.0% +60.8% ALNY
More profitableNet margin, trailing twelve months — 19.5% — –
Better return on capitalReturn on invested capital — 7.9% — –
Less leveragedLower net debt / EBITDA — 1.3x — –
Higher dividend yieldTrailing dividend yield 1.37% 5.24% — QGEN
Better 1-year returnPrice return, last 12 months -14.4% +1.4% -63.9% QGEN
Better 5-year returnAnnualised price return, 5 years -9.3%/yr -4.1%/yr +1.7%/yr ALNY
Less volatileAnnualised volatility, 1 year 32.5% 35.7% 58.8% GRFS
Higher overall scoreMean of the five percentile scores vs peers 56/100 71/100 65/100 QGEN

Percentile Scorecard

GRFSQGENALNY

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSQGENALNY
Valuation 99 #6 of 624 77 #54 of 227 70 #187 of 624
Growth – 31 #151 of 218 96 #27 of 601
Profitability – 93 #16 of 202 –
Financial Health 13 #563 of 647 63 #87 of 233 29 #463 of 647
Shareholder Returns 56 #159 of 359 93 #10 of 130 –
Overall 56 71 65
  • GRFS ranked among 671 companies in Pharmaceuticals and Biotechnology
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics
  • ALNY ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSQGENALNYSPY
1 month +10.1%+13.5%-31.5% +0.7%
3 months -2.0%+21.5%-15.3% +3.7%
6 months -2.4%+45.7%-43.8% +7.1%
Year to date -14.0%+6.4%-56.2% +12.8%
1 year -14.4%+1.4%-63.9% +11.9%
3 years +2.3%+27.0%+14.9% +85.2%
3 years, per year +0.8%+8.3%+4.7% +22.8%
5 years -38.7%-19.1%+9.0% +67.6%
5 years, per year -9.3%-4.1%+1.7% +10.9%
10 years -44.6%+75.8%+378.8% +262.0%
10 years, per year -5.7%+5.8%+17.0% +13.7%

Risk

MeasureGRFSQGENALNYSPY
Volatility, 1Y 32.5%35.7%58.8% 12.7%
Downside volatility, 1Y 34.1%30.5%74.8% 12.6%
Beta vs S&P 500, 1Y 0.950.470.42 1.00
Return / volatility, 1Y -0.440.04-1.09 0.94
Max drawdown, 5Y -58.8%-48.2%-64.6% -25.4%
From 52-week high -17.3%-9.5%-63.9% -1.2%
52-week high $9.72$55.66$481.59 $779.14
52-week low $7.02$32.63$174.00 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSQGENALNY
P/E now vs peer median 12.0xmedian 17.8x 26.7xmedian 28.7x 46.3xmedian 17.8x
P/S now vs peer median 0.6xmedian 9.1x 5.2xmedian 3.0x 4.6xmedian 9.1x
EV/EBITDA now vs peer median —median 15.0x 18.1xmedian 17.8x —median 15.0x
P/FCF now vs peer median 7.8xmedian 21.7x 11.0xmedian 26.4x 41.4xmedian 21.7x
P/B now vs peer median 0.6xmedian 2.2x 3.3xmedian 2.4x 6.5xmedian 2.2x
PEG now vs peer median —median 0.35 3.62median 0.99 —median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSQGENALNY
Revenue – $2.10B $5.01B
Gross profit – $1.31B –
Operating income – $445.43M $977.59M
Net income – $409.32M –
Free cash flow – $991.33M –
R&D – $194.67M $1.56B
EPS (diluted) – $1.87 –
Cash & equivalents $969.15M $768.50M $1.75B
Total debt $44.00B $6.86B –
Shares (diluted) 681.57M 218.88M 138.28M
Enterprise value $4.55B $6.70B $23.27B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSQGENALNY
P/E 12.0x 26.7x 46.3x
P/FCF 7.8x 11.0x 41.4x
P/Operating cash flow – 16.7x –
P/S 0.6x 5.2x 4.6x
P/B 0.6x 3.3x 6.5x
P/Tangible book 1.0x 3.6x 6.5x
EV/EBITDA – 18.1x –
EV/EBIT – 26.4x –
EV/Revenue – 5.6x 4.6x
EV/FCF – 11.9x –
EV/Operating cash flow – 18.0x –
PEG (3Y EPS CAGR) – 3.62 –

Growth

14 metrics
MetricGRFSQGENALNY
Revenue growth (1Y) – 3.0% 60.8%
Revenue CAGR (3Y) – 2.0% 42.7%
Gross profit growth (1Y) – 1.7% –
Gross profit CAGR (3Y) – 1.3% –
Operating income growth (1Y) – -4.9% 269.3%
Operating income CAGR (3Y) – 3.3% 68.2%
Net income growth (1Y) – 143.9% –
Net income CAGR (3Y) – 6.7% –
EPS growth (1Y) – 12.5% –
EPS CAGR (3Y) – 7.4% –
Operating cash flow growth (1Y) – -3.0% –
Operating cash flow CAGR (3Y) – 8.0% –
Free cash flow growth (1Y) – 2.3% –
Free cash flow CAGR (3Y) – 10.5% –

Profitability

14 metrics
MetricGRFSQGENALNY
Gross margin – 62.2% –
EBITDA margin – 31.0% –
Operating margin – 21.2% –
Pretax margin – 22.0% –
Net margin – 19.5% –
FCF margin – 47.2% –
Operating cash flow margin – 31.2% –
Return on equity – 12.2% –
Return on assets – 7.0% –
Return on invested capital – 7.9% –
Return on capital employed – 8.5% –
Asset turnover – 0.4x 0.7x
Cash conversion (OCF / net income) – 1.6x –
Stock comp / revenue – 2.1% –

Financial Health

11 metrics
MetricGRFSQGENALNY
Debt / assets 48.9% 27.9% –
Debt / equity 1.3x 0.5x –
Net debt / EBITDA – 1.3x –
Debt / FCF – 1.7x –
Liabilities / assets 61.4% 43.0% 54.9%
Equity / assets 38.6% 57.0% 45.1%
Interest coverage – 11.3x –
Current ratio 2.5x 2.8x 2.5x
Quick ratio 0.8x 2.0x –
Cash ratio 0.4x 1.4x –
Altman Z-score – 4.08 –

Shareholder Returns

7 metrics
MetricGRFSQGENALNY
Dividend yield 1.4% 5.2% –
Net buyback yield – 0.6% –
Shareholder yield 1.4% 5.8% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSQGENALNY
Forward P/E 8.6xFY2026 21.4xFY2026 25.7xFY2026
EPS, next fiscal year $0.94FY2026 $2.35FY2026 $6.76FY2026
EPS growth, next FY +10.6%FY2026 -1.3%FY2026 +190.1%FY2026
EPS growth, the year after +26.6% +17.4% +34.3%
Revenue, next fiscal year $8.88BFY2026 $2.25BFY2026 $5.68BFY2026
Revenue growth, next FY +0.0%FY2026 +7.8%FY2026 +53.1%FY2026
Revenue growth, the year after +10.3% -2.8% +27.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSQGENALNY
Held by institutions 21.0% 67.3% 99.7%
Institutions holding 167 338 787
Change in shares held, QoQ -0.5% +16.5% +3.8%
Institutions buying 74 216 412
Institutions selling 65 86 278
Buyers to sellers 1.14 2.51 1.48

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSQGENALNY
GRFS 1.00 0.17 0.19
QGEN 0.17 1.00 0.12
ALNY 0.19 0.12 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, QGEN and ALNY?

Alnylam Pharmaceuticals (ALNY) is the largest by market capitalisation: Grifols (GRFS) $5.47B, Qiagen (QGEN) $10.93B, Alnylam Pharmaceuticals (ALNY) $23.27B.

Which stock is cheaper, GRFS, QGEN and ALNY?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.0x, Qiagen (QGEN) 26.7x, Alnylam Pharmaceuticals (ALNY) 46.3x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 8.6x, Qiagen (QGEN) 21.4x, Alnylam Pharmaceuticals (ALNY) 25.7x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Alnylam Pharmaceuticals (ALNY) grew revenue fastest over the trailing twelve months: Qiagen (QGEN) +3.0%, Alnylam Pharmaceuticals (ALNY) +60.8%.

Which stock has performed better?

Over the past year Qiagen (QGEN) returned the most: Grifols (GRFS) -14.4%, Qiagen (QGEN) +1.4%, Alnylam Pharmaceuticals (ALNY) -63.9%. Over five years, Alnylam Pharmaceuticals (ALNY) compounded fastest (Grifols (GRFS) -9.3%/yr, Qiagen (QGEN) -4.1%/yr, Alnylam Pharmaceuticals (ALNY) +1.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Qiagen (QGEN) has the highest dividend yield: Grifols (GRFS) 1.37%, Qiagen (QGEN) 5.24%. Alnylam Pharmaceuticals (ALNY) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Grifols (GRFS) has been the steadiest (Grifols (GRFS) 32.5%, Qiagen (QGEN) 35.7%, Alnylam Pharmaceuticals (ALNY) 58.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, QGEN and ALNY?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Alnylam Pharmaceuticals (ALNY) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.