GRFS vs MRNA vs AMGN Stock Comparison

Grifols, Moderna and Amgen Prices as of Oct 27, 2026 Peers: Industry group
GRFS Grifols SA
$8.10 +10.2% 1M -13.6% 1Y
Market cap
$5.51B
P/E
12.1x
Revenue (TTM)
—
Div. yield
1.36%
Biotechnology Healthcare
2 wins
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$82.98B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
2 wins
AMGN Amgen Inc
$447.95 +8.0% 1M +53.9% 1Y
Market cap
$242.16B
P/E
27.7x
Revenue (TTM)
$38.10B
Div. yield
2.22%
Biotechnology Healthcare
8 wins

Head to Head

12 decided of 12

Amgen leads on 8 of the 12 questions below (Amgen 8, Grifols 2, Moderna 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRFSMRNAAMGNLeader
Larger companyMarket capitalisation $5.51B $82.98B $242.16B AMGN
Cheaper on earningsLower P/E, profitable companies only 12.1x -26.3x 27.7x GRFS
Cheaper on forward earningsLower price / next fiscal year consensus EPS 8.6x — 20.5x GRFS
Faster revenue growthRevenue growth, trailing twelve months — -27.6% +9.1% AMGN
More profitableNet margin, trailing twelve months — -141.4% 23.0% AMGN
Better return on capitalReturn on invested capital — -43.3% 14.3% AMGN
Less leveragedLower net debt / EBITDA — 1.5x 2.7x MRNA
Higher dividend yieldTrailing dividend yield 1.36% — 2.22% AMGN
Better 1-year returnPrice return, last 12 months -13.6% +680.1% +53.9% MRNA
Better 5-year returnAnnualised price return, 5 years -9.4%/yr -9.8%/yr +16.7%/yr AMGN
Less volatileAnnualised volatility, 1 year 32.4% 130.8% 29.6% AMGN
Higher overall scoreMean of the five percentile scores vs peers 56/100 57/100 66/100 AMGN

Percentile Scorecard

GRFSMRNAAMGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRFSMRNAAMGN
Valuation 99 #7 of 625 69 #193 of 625 86 #90 of 625
Growth – 18 #493 of 602 62 #231 of 602
Profitability – 57 #239 of 551 95 #31 of 551
Financial Health 14 #564 of 656 55 #298 of 656 22 #510 of 656
Shareholder Returns 56 #161 of 365 85 #57 of 365 68 #117 of 365
Overall 56 57 66
  • GRFS ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • AMGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRFSMRNAAMGNSPY
1 month +10.2%+4.6%+8.0% -0.2%
3 months +1.2%+272.6%+14.0% +3.9%
6 months +0.4%+341.2%+31.9% +8.2%
Year to date -13.4%+605.2%+36.9% +12.9%
1 year -13.6%+680.1%+53.9% +12.3%
3 years +3.3%+189.2%+71.3% +87.4%
3 years, per year +1.1%+42.5%+19.7% +23.3%
5 years -39.0%-40.2%+116.2% +67.9%
5 years, per year -9.4%-9.8%+16.7% +10.9%
10 years -44.7%—+179.0% +261.1%
10 years, per year -5.8%—+10.8% +13.7%

Risk

MeasureGRFSMRNAAMGNSPY
Volatility, 1Y 32.4%130.8%29.6% 12.7%
Downside volatility, 1Y 34.1%79.5%27.9% 12.7%
Beta vs S&P 500, 1Y 0.952.150.46 1.00
Return / volatility, 1Y -0.425.201.82 0.97
Max drawdown, 5Y -58.8%-93.9%-26.7% -25.4%
From 52-week high -16.7%-15.4%0.0% -1.2%
52-week high $9.72$245.81$447.95 $779.14
52-week low $7.02$22.36$291.16 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRFSMRNAAMGN
P/E now vs peer median 12.1xmedian 17.2x -26.3xmedian 17.2x 27.7xmedian 17.2x
P/S now vs peer median 0.6xmedian 9.0x 37.2xmedian 9.0x 6.4xmedian 9.0x
EV/EBITDA now vs peer median —median 16.3x -25.5xmedian 16.3x 17.7xmedian 16.3x
P/FCF now vs peer median 7.8xmedian 18.7x -66.7xmedian 18.7x 23.8xmedian 18.7x
P/B now vs peer median 0.6xmedian 2.2x 12.3xmedian 2.2x 20.7xmedian 2.2x
PEG now vs peer median —median 0.33 0.40median 0.33 10.44median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRFSMRNAAMGN
Revenue – $2.23B $38.10B
Gross profit – $521.00M $26.48B
Operating income – -$3.32B $11.43B
Net income – -$3.15B $8.74B
Free cash flow – -$1.24B $10.18B
R&D – $2.88B $7.63B
EPS (diluted) – $-7.92 $16.07
Cash & equivalents $969.15M $1.72B $13.99B
Total debt $44.00B $591.00M $57.30B
Shares (diluted) 681.57M 398.00M 544.00M
Enterprise value $4.59B $62.33B $197.56B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRFSMRNAAMGN
P/E 12.1x -26.3x 27.7x
P/FCF 7.8x -66.7x 23.8x
P/Operating cash flow – -77.3x 19.4x
P/S 0.6x 37.2x 6.4x
P/B 0.6x 12.3x 20.7x
P/Tangible book 1.0x 12.3x -27.5x
EV/EBITDA – -25.5x 17.7x
EV/EBIT – -23.6x 25.0x
EV/Revenue – 35.2x 7.5x
EV/FCF – -63.0x 28.1x
EV/Operating cash flow – -73.1x 22.9x
PEG (3Y EPS CAGR) – 0.40 10.44

Growth

14 metrics
MetricGRFSMRNAAMGN
Revenue growth (1Y) – -27.6% 9.1%
Revenue CAGR (3Y) – -40.6% 12.7%
Gross profit growth (1Y) – -67.8% 17.6%
Gross profit CAGR (3Y) – -56.0% 10.3%
Operating income growth (1Y) – -1.4% 39.5%
Operating income CAGR (3Y) – -103.9% 6.4%
Net income growth (1Y) – -8.5% 32.1%
Net income CAGR (3Y) – -66.4% 3.1%
EPS growth (1Y) – -5.8% 31.4%
EPS CAGR (3Y) – -65.1% 2.7%
Operating cash flow growth (1Y) – 60.2% 3.9%
Operating cash flow CAGR (3Y) – -68.1% 4.9%
Free cash flow growth (1Y) – 64.4% -4.1%
Free cash flow CAGR (3Y) – -18.2% 1.7%

Profitability

14 metrics
MetricGRFSMRNAAMGN
Gross margin – 23.4% 69.5%
EBITDA margin – -138.2% 42.2%
Operating margin – -149.0% 30.0%
Pretax margin – -138.6% 27.0%
Net margin – -141.4% 23.0%
FCF margin – -55.8% 26.7%
Operating cash flow margin – -48.2% 32.8%
Return on equity – -44.5% 83.8%
Return on assets – -28.1% 9.3%
Return on invested capital – -43.3% 14.3%
Return on capital employed – -38.2% 16.7%
Asset turnover – 0.2x 0.4x
Cash conversion (OCF / net income) – 0.3x 1.4x
Stock comp / revenue – 20.7% 1.3%

Financial Health

11 metrics
MetricGRFSMRNAAMGN
Debt / assets 48.9% 5.4% 59.9%
Debt / equity 1.3x 0.1x 4.9x
Net debt / EBITDA – 1.5x 2.7x
Debt / FCF – -0.5x 5.6x
Liabilities / assets 61.4% 38.3% 87.8%
Equity / assets 38.6% 61.7% 12.2%
Interest coverage – – 4.3x
Current ratio 2.5x 2.3x 1.4x
Quick ratio 0.8x 2.0x 0.9x
Cash ratio 0.4x 2.0x 0.5x
Altman Z-score – 12.07 2.32

Shareholder Returns

7 metrics
MetricGRFSMRNAAMGN
Dividend yield 1.4% – 2.2%
Net buyback yield – -0.1% –
Shareholder yield 1.4% -0.1% 2.2%
Payout ratio (earnings) – – 60.4%
Payout ratio (FCF) – – 51.9%
Dividend growth (1Y) – – 6.3%
Dividend CAGR (3Y) – – 6.7%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRFSMRNAAMGN
Forward P/E 8.6xFY2026 – 20.5xFY2026
EPS, next fiscal year $0.94FY2026 $-8.02FY2026 $21.81FY2026
EPS growth, next FY +10.6%FY2026 – -0.1%FY2026
EPS growth, the year after +26.6% – +7.2%
Revenue, next fiscal year $8.88BFY2026 $2.04BFY2026 $41.51BFY2026
Revenue growth, next FY +0.0%FY2026 +5.1%FY2026 +12.9%FY2026
Revenue growth, the year after +10.3% +26.8% +2.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRFSMRNAAMGN
Held by institutions 21.0% 80.2% 82.7%
Institutions holding 166 784 3,159
Change in shares held, QoQ -0.5% +3.4% +4.5%
Institutions buying 73 402 1,451
Institutions selling 65 238 1,217
Buyers to sellers 1.12 1.69 1.19

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRFSMRNAAMGN
GRFS 1.00 0.26 0.24
MRNA 0.26 1.00 0.25
AMGN 0.24 0.25 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRFS, MRNA and AMGN?

Amgen (AMGN) is the largest by market capitalisation: Grifols (GRFS) $5.51B, Moderna (MRNA) $82.98B, Amgen (AMGN) $242.16B.

Which stock is cheaper, GRFS, MRNA and AMGN?

Grifols (GRFS) trades on the lowest price-to-earnings ratio (Grifols (GRFS) 12.1x, Moderna (MRNA) -26.3x, Amgen (AMGN) 27.7x). On next year's consensus earnings, Grifols (GRFS) is cheapest (Grifols (GRFS) 8.6x, Amgen (AMGN) 20.5x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Amgen (AMGN) grew revenue fastest over the trailing twelve months: Moderna (MRNA) -27.6%, Amgen (AMGN) +9.1%.

Which company is more profitable?

Amgen (AMGN) has the highest net margin (Moderna (MRNA) -141.4%, Amgen (AMGN) 23.0%). On return on invested capital, Amgen (AMGN) leads (Moderna (MRNA) -43.3%, Amgen (AMGN) 14.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Grifols (GRFS) -13.6%, Moderna (MRNA) +680.1%, Amgen (AMGN) +53.9%. Over five years, Amgen (AMGN) compounded fastest (Grifols (GRFS) -9.4%/yr, Moderna (MRNA) -9.8%/yr, Amgen (AMGN) +16.7%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Amgen (AMGN) has the highest dividend yield: Grifols (GRFS) 1.36%, Amgen (AMGN) 2.22%. Moderna (MRNA) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Amgen (AMGN) has been the steadiest (Grifols (GRFS) 32.4%, Moderna (MRNA) 130.8%, Amgen (AMGN) 29.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRFS, MRNA and AMGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amgen (AMGN) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.