GRAL vs SHC vs BLLN Stock Comparison

Grail, Sotera Health and BillionToOne Prices as of Oct 27, 2026 Peers: Industry group
GRAL GRAIL, Inc.
$150.61 +18.7% 1M +77.2% 1Y
Market cap
$6.82B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare
2 wins
SHC Sotera Health Co
$18.49 +0.8% 1M +10.7% 1Y
Market cap
$5.32B
P/E
32.6x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
6 wins
BLLN BillionToOne, Inc.
$114.07 -7.3% 1M
Market cap
$5.29B
P/E
175.9x
Revenue (TTM)
$397.41M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

10 decided of 12

Sotera Health leads on 6 of the 12 questions below (Sotera Health 6, Grail 2, BillionToOne 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGRALSHCBLLNLeader
Larger companyMarket capitalisation $6.82B $5.32B $5.29B GRAL
Cheaper on earningsLower P/E, profitable companies only -17.4x 32.6x 175.9x SHC
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 20.1x 150.1x SHC
Faster revenue growthRevenue growth, trailing twelve months +17.1% +8.1% +90.1% BLLN
More profitableNet margin, trailing twelve months -249.1% 13.4% 7.6% SHC
Better return on capitalReturn on invested capital — 9.1% 7.0% SHC
Less leveragedLower net debt / EBITDA — 3.3x -9.1x BLLN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +77.2% +10.7% — GRAL
Better 5-year returnAnnualised price return, 5 years — -5.8%/yr — –
Less volatileAnnualised volatility, 1 year 111.3% 28.4% 94.5% SHC
Higher overall scoreMean of the five percentile scores vs peers 43/100 59/100 57/100 SHC

Percentile Scorecard

GRALSHCBLLN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGRALSHCBLLN
Valuation 8 #85 of 92 52 #45 of 92 20 #74 of 92
Growth 58 #37 of 87 66 #30 of 87 100 #1 of 87
Profitability 6 #81 of 86 82 #16 of 86 60 #35 of 86
Financial Health 99 #2 of 97 37 #62 of 97 97 #4 of 97
Shareholder Returns – – 7 #52 of 56
Overall 43 59 57
  • GRAL ranked among 102 companies in Healthcare Providers
  • SHC ranked among 102 companies in Healthcare Providers
  • BLLN ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGRALSHCBLLNSPY
1 month +18.7%+0.8%-7.3% -0.2%
3 months +133.8%+4.1%-14.6% +3.9%
6 months +188.5%+19.0%+45.8% +8.2%
Year to date +76.0%+4.8%+39.4% +12.9%
1 year +77.2%+10.7%— +12.3%
3 years —+47.8%— +87.4%
3 years, per year —+13.9%— +23.3%
5 years —-25.6%— +67.9%
5 years, per year —-5.8%— +10.9%

Risk

MeasureGRALSHCBLLNSPY
Volatility, 1Y 111.3%28.4%94.5% 12.7%
Downside volatility, 1Y 126.1%27.0%107.8% 12.7%
Beta vs S&P 500, 1Y 2.691.011.66 1.00
Return / volatility, 1Y 0.690.38— 0.97
Max drawdown, 5Y -62.9%-78.2%-50.8% -25.4%
From 52-week high -2.3%-5.5%-23.9% -1.2%
52-week high $154.08$19.57$149.97 $779.14
52-week low $43.03$13.13$64.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGRALSHCBLLN
P/E now vs peer median -16.6xmedian 24.6x 32.3xmedian 24.6x 176.1xmedian 24.6x
P/S now vs peer median 42.8xmedian 1.6x 4.3xmedian 1.6x 13.4xmedian 1.6x
EV/EBITDA now vs peer median -14.5xmedian 14.6x 13.0xmedian 14.6x 97.2xmedian 14.6x
P/FCF now vs peer median -22.7xmedian 21.6x 46.8xmedian 21.6x 161.0xmedian 21.6x
P/B now vs peer median 2.6xmedian 3.2x 7.9xmedian 3.2x 10.0xmedian 3.2x
PEG now vs peer median —median 0.66 0.86median 0.66 —median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGRALSHCBLLN
Revenue $157.21M $1.22B $397.41M
Gross profit $75.51M $668.51M $283.22M
Operating income -$559.25M $411.34M $43.30M
Net income -$391.59M $163.48M $37.71M
Free cash flow -$296.16M $112.70M $33.18M
R&D $190.72M – $59.21M
EPS (diluted) $-9.08 $0.57 $0.55
Cash & equivalents $55.65M $356.72M $548.63M
Total debt – $2.14B $91.03M
Shares (diluted) 43.11M 288.15M 54.46M
Enterprise value $3.69B $4.01B $3.51B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGRALSHCBLLN
P/E -16.6x 32.3x 176.1x
P/FCF -22.7x 46.8x 161.0x
P/Operating cash flow -22.8x 18.1x 117.8x
P/S 42.8x 4.3x 13.4x
P/B 2.6x 7.9x 10.0x
P/Tangible book 8.8x 13.3x 10.0x
EV/EBITDA -14.5x 13.0x 97.2x
EV/EBIT -10.5x 17.2x 112.8x
EV/Revenue 37.3x 5.8x 12.3x
EV/FCF -19.8x 62.6x 147.2x
EV/Operating cash flow -19.9x 24.2x 107.7x
PEG (3Y EPS CAGR) – 0.86 –

Growth

14 metrics
MetricGRALSHCBLLN
Revenue growth (1Y) 17.1% 8.1% 90.1%
Revenue CAGR (3Y) – 7.6% –
Gross profit growth (1Y) 30.2% 7.1% 122.4%
Gross profit CAGR (3Y) – 8.1% –
Operating income growth (1Y) 11.6% 21.8% 253.2%
Operating income CAGR (3Y) – 23.2% –
Net income growth (1Y) 11.6% 580.5% 223.2%
Net income CAGR (3Y) – 37.7% –
EPS growth (1Y) 26.6% 574.9% 118.7%
EPS CAGR (3Y) – 37.5% –
Operating cash flow growth (1Y) 20.3% 9.8% –
Operating cash flow CAGR (3Y) – 61.3% –
Free cash flow growth (1Y) 20.3% 0.0% –
Free cash flow CAGR (3Y) – 32.6% –

Profitability

14 metrics
MetricGRALSHCBLLN
Gross margin 48.0% 55.0% 71.3%
EBITDA margin -257.6% 44.6% 12.6%
Operating margin -355.7% 33.8% 10.9%
Pretax margin -336.8% 21.7% 9.5%
Net margin -249.1% 13.4% 7.6%
FCF margin -188.4% 9.3% 8.3%
Operating cash flow margin -187.5% 24.0% 11.4%
Return on equity -15.5% 25.4% 7.2%
Return on assets -13.9% 5.0% 5.3%
Return on invested capital – 9.1% 7.0%
Return on capital employed -20.4% 13.5% 6.6%
Asset turnover 0.1x 0.4x 0.6x
Cash conversion (OCF / net income) 0.8x 1.8x 1.2x
Stock comp / revenue 40.9% 3.1% 6.4%

Financial Health

11 metrics
MetricGRALSHCBLLN
Debt / assets – 64.7% 12.5%
Debt / equity – 3.2x 0.2x
Net debt / EBITDA – 3.3x -9.1x
Debt / FCF – 19.0x 2.7x
Liabilities / assets 10.6% 79.9% 26.4%
Equity / assets 89.4% 20.1% 73.6%
Interest coverage – – 1,056x
Current ratio 10.9x 2.8x 11.7x
Quick ratio 10.6x 2.4x 11.2x
Cash ratio 10.3x 1.5x 9.8x
Altman Z-score 8.04 1.94 17.86

Shareholder Returns

7 metrics
MetricGRALSHCBLLN
Dividend yield – – –
Net buyback yield – – -5.7%
Shareholder yield – – -5.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGRALSHCBLLN
Forward P/E – 20.1xFY2026 150.1xFY2026
EPS, next fiscal year $-9.05FY2026 $0.92FY2026 $0.76FY2026
EPS growth, next FY – +7.0%FY2026 +442.9%FY2026
EPS growth, the year after – +21.7% +22.4%
Revenue, next fiscal year $169.78MFY2026 $1.33BFY2026 $481.76MFY2026
Revenue growth, next FY +15.4%FY2026 +14.8%FY2026 +57.9%FY2026
Revenue growth, the year after +38.2% -4.2% +27.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGRALSHCBLLN
Held by institutions 85.4% 100.0% 32.6%
Institutions holding 372 316 155
Change in shares held, QoQ +8.4% +5.9% +34.7%
Institutions buying 182 220 127
Institutions selling 100 64 13
Buyers to sellers 1.82 3.44 9.77

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GRALSHCBLLN
GRAL 1.00 0.22 0.35
SHC 0.22 1.00 0.14
BLLN 0.35 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GRAL, SHC and BLLN?

Grail (GRAL) is the largest by market capitalisation: Grail (GRAL) $6.82B, Sotera Health (SHC) $5.32B, BillionToOne (BLLN) $5.29B.

Which stock is cheaper, GRAL, SHC and BLLN?

Sotera Health (SHC) trades on the lowest price-to-earnings ratio (Grail (GRAL) -17.4x, Sotera Health (SHC) 32.6x, BillionToOne (BLLN) 175.9x). On next year's consensus earnings, Sotera Health (SHC) is cheapest (Sotera Health (SHC) 20.1x, BillionToOne (BLLN) 150.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: Grail (GRAL) +17.1%, Sotera Health (SHC) +8.1%, BillionToOne (BLLN) +90.1%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Grail (GRAL) -249.1%, Sotera Health (SHC) 13.4%, BillionToOne (BLLN) 7.6%). On return on invested capital, Sotera Health (SHC) leads (Sotera Health (SHC) 9.1%, BillionToOne (BLLN) 7.0%).

Which stock has performed better?

Over the past year Grail (GRAL) returned the most: Grail (GRAL) +77.2%, Sotera Health (SHC) +10.7%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Grail (GRAL) 111.3%, Sotera Health (SHC) 28.4%, BillionToOne (BLLN) 94.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GRAL, SHC and BLLN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Sotera Health (SHC) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.