GILD vs VRTX vs ROIV Stock Comparison

Gilead Sciences, Vertex Pharmaceuticals and Roivant Sciences Prices as of Oct 26, 2026 Peers: Industry group
GILD Gilead Sciences, Inc.
$158.69 +5.1% 1M +31.2% 1Y
Market cap
$197.36B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
2 wins
ROIV Roivant Sciences Ltd.
$36.05 +0.7% 1M +97.9% 1Y
Market cap
$26.33B
P/E
–
Revenue (TTM)
$7.53M
Div. yield
–
Biotechnology Healthcare
2 wins

Head to Head

7 decided of 12

Vertex Pharmaceuticals leads on 3 of the 12 questions below (Vertex Pharmaceuticals 3, Gilead Sciences 2, Roivant Sciences 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGILDVRTXROIVLeader
Larger companyMarket capitalisation $197.36B $132.05B $26.33B GILD
Cheaper on earningsLower P/E, profitable companies only -60.9x 30.0x -98.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 28.4x — –
Faster revenue growthRevenue growth, trailing twelve months +5.5% +10.2% -67.6% VRTX
More profitableNet margin, trailing twelve months -10.6% 35.0% -3,535.0% VRTX
Better return on capitalReturn on invested capital -6.0% — — –
Less leveragedLower net debt / EBITDA 87.7x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +31.2% +22.8% +97.9% ROIV
Better 5-year returnAnnualised price return, 5 years +18.9%/yr +23.4%/yr +36.1%/yr ROIV
Less volatileAnnualised volatility, 1 year 27.0% 29.0% 45.3% GILD
Higher overall scoreMean of the five percentile scores vs peers 61/100 76/100 65/100 VRTX

Percentile Scorecard

GILDVRTXROIV

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGILDVRTXROIV
Valuation 90 #62 of 626 80 #124 of 626 64 #229 of 626
Growth 31 #420 of 604 60 #245 of 604 49 #308 of 604
Profitability 85 #85 of 555 95 #31 of 555 30 #387 of 555
Financial Health 21 #518 of 658 53 #308 of 658 93 #47 of 658
Shareholder Returns 77 #85 of 368 93 #27 of 368 91 #36 of 368
Overall 61 76 65
  • GILD ranked among 673 companies in Pharmaceuticals and Biotechnology
  • VRTX ranked among 673 companies in Pharmaceuticals and Biotechnology
  • ROIV ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGILDVRTXROIVSPY
1 month +5.1%-1.7%+0.7% -0.8%
3 months +21.6%+8.0%+3.8% +3.5%
6 months +24.2%+21.5%+29.4% +7.0%
Year to date +29.3%+14.1%+66.1% +12.2%
1 year +31.2%+22.8%+97.9% +13.0%
3 years +107.1%+45.7%+330.2% +86.3%
3 years, per year +27.5%+13.4%+62.7% +23.1%
5 years +137.7%+186.0%+365.8% +68.6%
5 years, per year +18.9%+23.4%+36.1% +11.0%
10 years +110.5%+557.5%— +258.0%
10 years, per year +7.7%+20.7%— +13.6%

Risk

MeasureGILDVRTXROIVSPY
Volatility, 1Y 27.0%29.0%45.3% 12.7%
Downside volatility, 1Y 24.0%25.8%32.6% 12.7%
Beta vs S&P 500, 1Y 0.300.490.97 1.00
Return / volatility, 1Y 1.160.792.16 1.02
Max drawdown, 5Y -29.4%-29.1%-79.2% -25.4%
From 52-week high 0.0%-7.3%-13.8% -1.8%
52-week high $158.69$557.96$41.81 $779.14
52-week low $117.88$409.47$18.41 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGILDVRTXROIV
P/E now vs peer median -60.9xmedian 17.1x 29.8xmedian 17.1x -97.6xmedian 17.1x
P/S now vs peer median 6.5xmedian 8.8x 10.4xmedian 8.8x 3,459xmedian 8.8x
EV/EBITDA now vs peer median 836.5xmedian 17.1x 24.7xmedian 17.1x -37.4xmedian 17.1x
P/FCF now vs peer median 15.2xmedian 18.0x 34.5xmedian 18.0x -31.7xmedian 18.0x
P/B now vs peer median 16.6xmedian 2.1x 6.5xmedian 2.1x 5.3xmedian 2.1x
PEG now vs peer median 1.62median 0.31 2.94median 0.31 -2.88median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGILDVRTXROIV
Revenue $30.46B $12.59B $7.53M
Gross profit $24.24B $10.82B $6.12M
Operating income -$2.50B $4.78B -$596.14M
Net income -$3.24B $4.41B -$414.60M
Free cash flow $12.94B $3.80B -$821.06M
R&D $6.07B $3.91B $730.91M
EPS (diluted) $-2.61 $17.26 $-0.37
Cash & equivalents $3.18B $6.14B $1.25B
Total debt $26.25B – –
Shares (diluted) 1.24B 255.20M 720.78M
Enterprise value $171.56B $104.06B $9.28B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGILDVRTXROIV
P/E -60.9x 29.8x -97.6x
P/FCF 15.2x 34.5x -31.7x
P/Operating cash flow 14.5x 30.5x -31.9x
P/S 6.5x 10.4x 3,459x
P/B 16.6x 6.5x 5.3x
P/Tangible book -89.4x 6.6x 5.3x
EV/EBITDA 836.5x 24.7x -37.4x
EV/EBIT -88.1x 25.8x -37.3x
EV/Revenue 7.2x 9.8x 2,949x
EV/FCF 17.0x 32.5x -27.1x
EV/Operating cash flow 16.2x 28.7x -27.2x
PEG (3Y EPS CAGR) 1.62 2.94 -2.88

Growth

14 metrics
MetricGILDVRTXROIV
Revenue growth (1Y) 5.5% 10.2% -67.6%
Revenue CAGR (3Y) 3.6% 9.8% -46.4%
Gross profit growth (1Y) 6.9% 10.1% -72.7%
Gross profit CAGR (3Y) 3.7% 9.0% -47.9%
Operating income growth (1Y) -131.0% 21.8% 49.7%
Operating income CAGR (3Y) -31.9% 6.4% 12.9%
Net income growth (1Y) -151.3% 21.1% 34.9%
Net income CAGR (3Y) -37.3% 9.4% 26.5%
EPS growth (1Y) -151.8% 22.9% 48.8%
EPS CAGR (3Y) -37.5% 10.1% 33.9%
Operating cash flow growth (1Y) 37.3% 11.6% 4.1%
Operating cash flow CAGR (3Y) 12.5% 1.8% 1.0%
Free cash flow growth (1Y) 38.1% 8.5% 4.4%
Free cash flow CAGR (3Y) 13.2% -0.7% 1.0%

Profitability

14 metrics
MetricGILDVRTXROIV
Gross margin 79.6% 86.0% 81.2%
EBITDA margin 0.9% 39.7% -7,877%
Operating margin -8.2% 38.0% -7,915%
Pretax margin -6.4% 41.9% -3,849%
Net margin -10.6% 35.0% -3,535%
FCF margin 42.5% 30.2% -10,901%
Operating cash flow margin 44.5% 34.1% -10,840%
Return on equity -18.4% 22.2% -8.1%
Return on assets -6.1% 16.3% -7.5%
Return on invested capital -6.0% – –
Return on capital employed -6.0% 20.8% -11.4%
Asset turnover 0.6x 0.5x 0.0x
Cash conversion (OCF / net income) -4.2x 1.0x 2.0x
Stock comp / revenue 3.0% 5.5% 4,611%

Financial Health

11 metrics
MetricGILDVRTXROIV
Debt / assets 53.2% – –
Debt / equity 2.2x – –
Net debt / EBITDA 87.7x – –
Debt / FCF 2.0x – –
Liabilities / assets 76.0% 26.2% 7.2%
Equity / assets 24.0% 73.8% 92.8%
Interest coverage -2.5x – –
Current ratio 1.3x 3.2x 16.7x
Quick ratio 0.7x 2.5x 13.5x
Cash ratio 0.3x 2.0x 13.5x
Altman Z-score 3.73 13.17 41.04

Shareholder Returns

7 metrics
MetricGILDVRTXROIV
Dividend yield 2.0% – –
Net buyback yield 0.6% 1.4% 0.0%
Shareholder yield 2.6% 1.4% 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGILDVRTXROIV
Forward P/E – 28.4xFY2026 –
EPS, next fiscal year $-0.39FY2026 $18.24FY2026 $-1.43FY2026
EPS growth, next FY -104.8%FY2026 -0.9%FY2026 –
EPS growth, the year after – +23.0% –
Revenue, next fiscal year $28.65BFY2026 $12.67BFY2026 $55.64MFY2026
Revenue growth, next FY -2.7%FY2026 +5.8%FY2026 +573.6%FY2026
Revenue growth, the year after +18.1% +18.8% +681.6%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGILDVRTXROIV
Held by institutions 89.6% 95.1% 77.0%
Institutions holding 2,290 1,745 498
Change in shares held, QoQ +5.1% +3.9% +5.1%
Institutions buying 1,113 902 303
Institutions selling 850 605 138
Buyers to sellers 1.31 1.49 2.20

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GILDVRTXROIV
GILD 1.00 0.48 0.08
VRTX 0.48 1.00 0.22
ROIV 0.08 0.22 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, GILD, VRTX and ROIV?

Gilead Sciences (GILD) is the largest by market capitalisation: Gilead Sciences (GILD) $197.36B, Vertex Pharmaceuticals (VRTX) $132.05B, Roivant Sciences (ROIV) $26.33B.

Which company is growing faster?

Vertex Pharmaceuticals (VRTX) grew revenue fastest over the trailing twelve months: Gilead Sciences (GILD) +5.5%, Vertex Pharmaceuticals (VRTX) +10.2%, Roivant Sciences (ROIV) -67.6%.

Which company is more profitable?

Vertex Pharmaceuticals (VRTX) has the highest net margin (Gilead Sciences (GILD) -10.6%, Vertex Pharmaceuticals (VRTX) 35.0%, Roivant Sciences (ROIV) -3,535.0%).

Which stock has performed better?

Over the past year Roivant Sciences (ROIV) returned the most: Gilead Sciences (GILD) +31.2%, Vertex Pharmaceuticals (VRTX) +22.8%, Roivant Sciences (ROIV) +97.9%. Over five years, Roivant Sciences (ROIV) compounded fastest (Gilead Sciences (GILD) +18.9%/yr, Vertex Pharmaceuticals (VRTX) +23.4%/yr, Roivant Sciences (ROIV) +36.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Gilead Sciences (GILD) 27.0%, Vertex Pharmaceuticals (VRTX) 29.0%, Roivant Sciences (ROIV) 45.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GILD, VRTX and ROIV?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Vertex Pharmaceuticals (VRTX) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.