GILD vs REGN vs BNTX Stock Comparison

Gilead Sciences, Regeneron Pharmaceuticals and BioNTech SE Prices as of Oct 26, 2026 Peers: Industry group
GILD Gilead Sciences, Inc.
$158.69 +5.1% 1M +31.2% 1Y
Market cap
$197.86B
P/E
–
Revenue (TTM)
$30.46B
Div. yield
–
Biotechnology Healthcare
3 wins
BNTX BioNTech SE
$86.86 -11.8% 1M -17.8% 1Y
Market cap
$21.06B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare

Head to Head

9 decided of 12

Regeneron Pharmaceuticals leads on 6 of the 12 questions below (Regeneron Pharmaceuticals 6, Gilead Sciences 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGILDREGNBNTXLeader
Larger companyMarket capitalisation $197.86B $83.80B $21.06B GILD
Cheaper on earningsLower P/E, profitable companies only -61.1x 19.4x -10.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 14.1x — –
Faster revenue growthRevenue growth, trailing twelve months +5.5% +9.3% -1.1% REGN
More profitableNet margin, trailing twelve months -10.6% 27.9% -63.5% REGN
Better return on capitalReturn on invested capital -6.0% 9.6% -10.7% REGN
Less leveragedLower net debt / EBITDA 87.7x -1.4x 8.7x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +31.2% +39.7% -17.8% REGN
Better 5-year returnAnnualised price return, 5 years +18.9%/yr +6.5%/yr -20.8%/yr GILD
Less volatileAnnualised volatility, 1 year 27.0% 32.9% 46.7% GILD
Higher overall scoreMean of the five percentile scores vs peers 61/100 72/100 64/100 REGN

Percentile Scorecard

GILDREGNBNTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGILDREGNBNTX
Valuation 90 #62 of 626 89 #72 of 626 91 #59 of 626
Growth 31 #420 of 604 42 #353 of 604 14 #522 of 604
Profitability 85 #85 of 555 90 #55 of 555 76 #132 of 555
Financial Health 21 #518 of 658 74 #172 of 658 89 #72 of 658
Shareholder Returns 77 #85 of 368 65 #129 of 368 51 #180 of 368
Overall 61 72 64
  • GILD ranked among 673 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 673 companies in Pharmaceuticals and Biotechnology
  • BNTX ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGILDREGNBNTXSPY
1 month +5.1%+2.5%-11.8% -0.8%
3 months +21.6%+21.1%-4.6% +3.5%
6 months +24.2%+8.5%-14.9% +7.0%
Year to date +29.3%+4.6%-8.8% +12.2%
1 year +31.2%+39.7%-17.8% +13.0%
3 years +107.1%+4.2%-4.8% +86.3%
3 years, per year +27.5%+1.4%-1.6% +23.1%
5 years +137.7%+37.0%-68.8% +68.6%
5 years, per year +18.9%+6.5%-20.8% +11.0%
10 years +110.5%+122.4%— +258.0%
10 years, per year +7.7%+8.3%— +13.6%

Risk

MeasureGILDREGNBNTXSPY
Volatility, 1Y 27.0%32.9%46.7% 12.7%
Downside volatility, 1Y 24.0%30.0%46.5% 12.7%
Beta vs S&P 500, 1Y 0.300.460.95 1.00
Return / volatility, 1Y 1.161.21-0.38 1.02
Max drawdown, 5Y -29.4%-59.8%-78.4% -25.4%
From 52-week high 0.0%-5.2%-27.2% -1.8%
52-week high $158.69$852.03$119.34 $779.14
52-week low $117.88$585.31$83.89 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGILDREGNBNTX
P/E now vs peer median -60.9xmedian 17.1x 19.2xmedian 17.1x -10.7xmedian 17.1x
P/S now vs peer median 6.5xmedian 8.8x 5.3xmedian 8.8x 7.1xmedian 8.8x
EV/EBITDA now vs peer median 836.5xmedian 17.1x 17.6xmedian 17.1x -5.6xmedian 17.1x
P/FCF now vs peer median 15.2xmedian 18.0x 22.1xmedian 18.0x 21.2xmedian 18.0x
P/B now vs peer median 16.6xmedian 2.1x 2.6xmedian 2.1x 1.1xmedian 2.1x
PEG now vs peer median 1.62median 0.31 7.21median 0.31 0.31median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGILDREGNBNTX
Revenue $30.46B $15.53B $3.09B
Gross profit $24.24B $13.18B $2.34B
Operating income -$2.50B $3.84B -$2.33B
Net income -$3.24B $4.33B -$1.97B
Free cash flow $12.94B $3.76B $1.04B
R&D $6.07B $6.28B $2.54B
EPS (diluted) $-2.61 $40.84 $-8.13
Cash & equivalents $3.18B $2.46B $11.13B
Total debt $26.25B $1.99B $102.80M
Shares (diluted) 1.24B 106.00M 241.70M
Enterprise value $172.06B $50.01B -$25.41B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGILDREGNBNTX
P/E -60.9x 19.2x -10.7x
P/FCF 15.2x 22.1x 21.2x
P/Operating cash flow 14.5x 17.7x 27.7x
P/S 6.5x 5.3x 7.1x
P/B 16.6x 2.6x 1.1x
P/Tangible book -89.4x 2.7x 1.1x
EV/EBITDA 836.5x 17.6x -5.6x
EV/EBIT -88.1x 20.0x -3.7x
EV/Revenue 7.2x 5.0x 2.8x
EV/FCF 17.0x 20.5x 8.3x
EV/Operating cash flow 16.2x 16.5x 10.9x
PEG (3Y EPS CAGR) 1.62 7.21 0.31

Growth

14 metrics
MetricGILDREGNBNTX
Revenue growth (1Y) 5.5% 9.3% -1.1%
Revenue CAGR (3Y) 3.6% 7.0% -31.0%
Gross profit growth (1Y) 6.9% 8.4% -6.4%
Gross profit CAGR (3Y) 3.7% 6.4% -34.2%
Operating income growth (1Y) -131.0% 0.1% -142.6%
Operating income CAGR (3Y) -31.9% -3.9% -33.8%
Net income growth (1Y) -151.3% -2.9% -417.0%
Net income CAGR (3Y) -37.3% 0.2% -34.6%
EPS growth (1Y) -151.8% -0.5% -393.7%
EPS CAGR (3Y) -37.5% 2.7% -34.9%
Operating cash flow growth (1Y) 37.3% -1.3% 142.8%
Operating cash flow CAGR (3Y) 12.5% -0.4% -56.6%
Free cash flow growth (1Y) 38.1% -2.4% 164.1%
Free cash flow CAGR (3Y) 13.2% -3.3% -53.1%

Profitability

14 metrics
MetricGILDREGNBNTX
Gross margin 79.6% 84.9% 75.5%
EBITDA margin 0.9% 28.1% -49.7%
Operating margin -8.2% 24.7% -75.2%
Pretax margin -6.4% 33.3% -61.4%
Net margin -10.6% 27.9% -63.5%
FCF margin 42.5% 24.2% 33.6%
Operating cash flow margin 44.5% 30.1% 25.6%
Return on equity -18.4% 13.7% -10.3%
Return on assets -6.1% 10.5% -9.0%
Return on invested capital -6.0% 9.6% -10.7%
Return on capital employed -6.0% 10.7% -9.9%
Asset turnover 0.6x 0.4x 0.1x
Cash conversion (OCF / net income) -4.2x 1.1x -0.4x
Stock comp / revenue 3.0% 6.4% 3.6%

Financial Health

11 metrics
MetricGILDREGNBNTX
Debt / assets 53.2% 4.8% 0.4%
Debt / equity 2.2x 0.1x 0.0x
Net debt / EBITDA 87.7x -1.4x 8.7x
Debt / FCF 2.0x 0.5x 0.1x
Liabilities / assets 76.0% 24.0% 12.7%
Equity / assets 24.0% 76.0% 87.3%
Interest coverage -2.5x 69.4x -41.1x
Current ratio 1.3x 3.3x 65.1x
Quick ratio 0.7x 2.6x 50.7x
Cash ratio 0.3x 1.4x 50.0x
Altman Z-score 3.73 7.28 6.30

Shareholder Returns

7 metrics
MetricGILDREGNBNTX
Dividend yield 2.0% 0.5% –
Net buyback yield 0.6% 3.1% -3.0%
Shareholder yield 2.6% 3.5% -3.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGILDREGNBNTX
Forward P/E – 14.1xFY2026 –
EPS, next fiscal year $-0.39FY2026 $57.08FY2026 $-6.21FY2026
EPS growth, next FY -104.8%FY2026 +28.8%FY2026 –
EPS growth, the year after – +15.5% –
Revenue, next fiscal year $28.65BFY2026 $17.05BFY2026 $1.90BFY2026
Revenue growth, next FY -2.7%FY2026 +18.9%FY2026 -43.7%FY2026
Revenue growth, the year after +18.1% +13.0% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGILDREGNBNTX
Held by institutions 89.6% 66.2% 19.4%
Institutions holding 2,290 1,325 281
Change in shares held, QoQ +5.1% +3.8% -1.2%
Institutions buying 1,113 604 136
Institutions selling 850 534 73
Buyers to sellers 1.31 1.13 1.86

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GILDREGNBNTX
GILD 1.00 0.43 0.26
REGN 0.43 1.00 0.26
BNTX 0.26 0.26 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, GILD, REGN and BNTX?

Gilead Sciences (GILD) is the largest by market capitalisation: Gilead Sciences (GILD) $197.86B, Regeneron Pharmaceuticals (REGN) $83.80B, BioNTech SE (BNTX) $21.06B.

Which company is growing faster?

Regeneron Pharmaceuticals (REGN) grew revenue fastest over the trailing twelve months: Gilead Sciences (GILD) +5.5%, Regeneron Pharmaceuticals (REGN) +9.3%, BioNTech SE (BNTX) -1.1%.

Which company is more profitable?

Regeneron Pharmaceuticals (REGN) has the highest net margin (Gilead Sciences (GILD) -10.6%, Regeneron Pharmaceuticals (REGN) 27.9%, BioNTech SE (BNTX) -63.5%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (Gilead Sciences (GILD) -6.0%, Regeneron Pharmaceuticals (REGN) 9.6%, BioNTech SE (BNTX) -10.7%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: Gilead Sciences (GILD) +31.2%, Regeneron Pharmaceuticals (REGN) +39.7%, BioNTech SE (BNTX) -17.8%. Over five years, Gilead Sciences (GILD) compounded fastest (Gilead Sciences (GILD) +18.9%/yr, Regeneron Pharmaceuticals (REGN) +6.5%/yr, BioNTech SE (BNTX) -20.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Gilead Sciences (GILD) has been the steadiest (Gilead Sciences (GILD) 27.0%, Regeneron Pharmaceuticals (REGN) 32.9%, BioNTech SE (BNTX) 46.7%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GILD, REGN and BNTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.