GH vs IQV vs BLLN Stock Comparison

Guardant Health, Iqvia Holdings and BillionToOne Prices as of Oct 27, 2026 Peers: Industry group
GH Guardant Health, Inc.
$178.06 +0.5% 1M +151.3% 1Y
Market cap
$23.79B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
2 wins
IQV Iqvia Holdings Inc.
$271.68 +0.7% 1M +25.0% 1Y
Market cap
$44.77B
P/E
32.1x
Revenue (TTM)
$17.31B
Div. yield
–
Contract Research Healthcare
7 wins
BLLN BillionToOne, Inc.
$114.07 -7.3% 1M
Market cap
$5.34B
P/E
176.1x
Revenue (TTM)
$397.41M
Div. yield
–
Diagnostic Labs Healthcare
2 wins

Head to Head

11 decided of 12

Iqvia Holdings leads on 7 of the 12 questions below (Iqvia Holdings 7, BillionToOne 2, Guardant Health 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGHIQVBLLNLeader
Larger companyMarket capitalisation $23.79B $44.77B $5.34B IQV
Cheaper on earningsLower P/E, profitable companies only -52.2x 32.1x 176.1x IQV
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 22.4x 150.1x IQV
Faster revenue growthRevenue growth, trailing twelve months +42.7% +8.8% +90.1% BLLN
More profitableNet margin, trailing twelve months -38.3% 8.1% 7.6% IQV
Better return on capitalReturn on invested capital — 8.2% 7.0% IQV
Less leveragedLower net debt / EBITDA — 3.9x -9.1x BLLN
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +151.3% +25.0% — GH
Better 5-year returnAnnualised price return, 5 years +8.5%/yr +1.1%/yr — GH
Less volatileAnnualised volatility, 1 year 57.4% 40.3% 94.5% IQV
Higher overall scoreMean of the five percentile scores vs peers 28/100 71/100 57/100 IQV

Percentile Scorecard

GHIQVBLLN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGHIQVBLLN
Valuation 18 #76 of 92 80 #3 of 11 20 #74 of 92
Growth 49 #45 of 87 80 #3 of 11 100 #1 of 87
Profitability 7 #80 of 86 90 #2 of 11 60 #35 of 86
Financial Health 52 #47 of 97 33 #9 of 13 97 #4 of 97
Shareholder Returns 15 #48 of 56 – 7 #52 of 56
Overall 28 71 57
  • GH ranked among 102 companies in Healthcare Providers
  • IQV ranked among 13 companies in Pharma Services
  • BLLN ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGHIQVBLLNSPY
1 month +0.5%+0.7%-7.3% -0.2%
3 months +24.0%+11.7%-14.6% +3.9%
6 months +114.3%+70.9%+45.8% +8.2%
Year to date +74.3%+20.5%+39.4% +12.9%
1 year +151.3%+25.0%— +12.3%
3 years +613.4%+51.0%— +87.4%
3 years, per year +92.6%+14.7%— +23.3%
5 years +50.7%+5.6%— +67.9%
5 years, per year +8.5%+1.1%— +10.9%
10 years —+276.8%— +261.1%
10 years, per year —+14.2%— +13.7%

Risk

MeasureGHIQVBLLNSPY
Volatility, 1Y 57.4%40.3%94.5% 12.7%
Downside volatility, 1Y 48.7%39.2%107.8% 12.7%
Beta vs S&P 500, 1Y 1.030.741.66 1.00
Return / volatility, 1Y 2.640.62— 0.97
Max drawdown, 5Y -86.7%-51.5%-50.8% -25.4%
From 52-week high -4.9%-2.8%-23.9% -1.2%
52-week high $187.22$279.38$149.97 $779.14
52-week low $69.58$156.66$64.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGHIQVBLLN
P/E now vs peer median -52.2xmedian 24.6x 32.1xmedian 32.1x 176.1xmedian 24.6x
P/S now vs peer median 20.1xmedian 1.6x 2.6xmedian 2.6x 13.4xmedian 1.6x
EV/EBITDA now vs peer median -52.7xmedian 14.6x 16.9xmedian 38.1x 97.2xmedian 14.6x
P/FCF now vs peer median -98.8xmedian 21.6x 21.5xmedian 21.5x 161.0xmedian 21.6x
P/B now vs peer median -106.8xmedian 3.2x 6.6xmedian 3.1x 10.0xmedian 3.2x
PEG now vs peer median -5.25median 0.66 2.78median 2.03 —median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGHIQVBLLN
Revenue $1.18B $17.31B $397.41M
Gross profit $769.16M $5.72B $283.22M
Operating income -$470.26M $2.22B $43.30M
Net income -$453.44M $1.40B $37.71M
Free cash flow -$240.72M $2.08B $33.18M
R&D $375.79M – $59.21M
EPS (diluted) $-3.41 $8.35 $0.55
Cash & equivalents $1.05B $2.25B $548.63M
Total debt – $16.07B $91.03M
Shares (diluted) 132.87M 167.00M 54.46M
Enterprise value $19.85B $36.16B $3.56B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGHIQVBLLN
P/E -52.2x 32.1x 176.1x
P/FCF -98.8x 21.5x 161.0x
P/Operating cash flow -128.5x 16.4x 117.8x
P/S 20.1x 2.6x 13.4x
P/B -106.8x 6.6x 10.0x
P/Tangible book -95.9x 21.8x 10.0x
EV/EBITDA -52.7x 16.9x 97.2x
EV/EBIT -48.4x 26.3x 112.8x
EV/Revenue 19.2x 3.4x 12.3x
EV/FCF -94.5x 28.1x 147.2x
EV/Operating cash flow -122.8x 21.4x 107.7x
PEG (3Y EPS CAGR) -5.25 2.78 –

Growth

14 metrics
MetricGHIQVBLLN
Revenue growth (1Y) 42.7% 8.8% 90.1%
Revenue CAGR (3Y) 32.4% 5.2% –
Gross profit growth (1Y) 47.7% 6.6% 122.4%
Gross profit CAGR (3Y) – 3.4% –
Operating income growth (1Y) -2.1% 1.7% 253.2%
Operating income CAGR (3Y) 4.8% 6.2% –
Net income growth (1Y) -9.6% 9.0% 223.2%
Net income CAGR (3Y) 3.7% 7.8% –
EPS growth (1Y) -2.4% 11.7% 118.7%
EPS CAGR (3Y) 9.9% 11.5% –
Operating cash flow growth (1Y) 22.4% -2.4% –
Operating cash flow CAGR (3Y) 18.1% 11.7% –
Free cash flow growth (1Y) 11.4% -6.0% –
Free cash flow CAGR (3Y) 14.4% 16.3% –

Profitability

14 metrics
MetricGHIQVBLLN
Gross margin 65.0% 33.1% 71.3%
EBITDA margin -36.5% 20.0% 12.6%
Operating margin -39.7% 12.8% 10.9%
Pretax margin -38.4% 9.0% 9.5%
Net margin -38.3% 8.1% 7.6%
FCF margin -20.3% 12.0% 8.3%
Operating cash flow margin -15.7% 15.8% 11.4%
Return on equity – 21.4% 7.2%
Return on assets -23.7% 4.6% 5.3%
Return on invested capital – 8.2% 7.0%
Return on capital employed -29.9% 9.9% 6.6%
Asset turnover 0.6x 0.6x 0.6x
Cash conversion (OCF / net income) 0.4x 2.0x 1.2x
Stock comp / revenue 16.2% 1.8% 6.4%

Financial Health

11 metrics
MetricGHIQVBLLN
Debt / assets – 52.7% 12.5%
Debt / equity – 2.4x 0.2x
Net debt / EBITDA – 3.9x -9.1x
Debt / FCF – 7.7x 2.7x
Liabilities / assets 111.7% 77.7% 26.4%
Equity / assets -11.7% 22.3% 73.6%
Interest coverage -97.6x 2.8x 1,056x
Current ratio 4.0x 0.8x 11.7x
Quick ratio 3.5x 1.0x 11.2x
Cash ratio 3.1x 0.3x 9.8x
Altman Z-score 4.77 2.27 17.86

Shareholder Returns

7 metrics
MetricGHIQVBLLN
Dividend yield – – –
Net buyback yield -1.7% 2.6% -5.7%
Shareholder yield -1.7% 2.6% -5.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGHIQVBLLN
Forward P/E – 22.4xFY2026 150.1xFY2026
EPS, next fiscal year $-3.33FY2026 $12.14FY2026 $0.76FY2026
EPS growth, next FY – +1.8%FY2026 +442.9%FY2026
EPS growth, the year after – +13.3% +22.4%
Revenue, next fiscal year $1.42BFY2026 $18.58BFY2026 $481.76MFY2026
Revenue growth, next FY +44.5%FY2026 +13.9%FY2026 +57.9%FY2026
Revenue growth, the year after +27.0% -3.5% +27.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGHIQVBLLN
Held by institutions 100.0% 94.1% 32.6%
Institutions holding 594 1,083 155
Change in shares held, QoQ -2.6% +0.3% +34.7%
Institutions buying 353 530 127
Institutions selling 180 424 13
Buyers to sellers 1.96 1.25 9.77

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GHIQVBLLN
GH 1.00 0.26 0.30
IQV 0.26 1.00 0.20
BLLN 0.30 0.20 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GH, IQV and BLLN?

Iqvia Holdings (IQV) is the largest by market capitalisation: Guardant Health (GH) $23.79B, Iqvia Holdings (IQV) $44.77B, BillionToOne (BLLN) $5.34B.

Which stock is cheaper, GH, IQV and BLLN?

Iqvia Holdings (IQV) trades on the lowest price-to-earnings ratio (Guardant Health (GH) -52.2x, Iqvia Holdings (IQV) 32.1x, BillionToOne (BLLN) 176.1x). On next year's consensus earnings, Iqvia Holdings (IQV) is cheapest (Iqvia Holdings (IQV) 22.4x, BillionToOne (BLLN) 150.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: Guardant Health (GH) +42.7%, Iqvia Holdings (IQV) +8.8%, BillionToOne (BLLN) +90.1%.

Which company is more profitable?

Iqvia Holdings (IQV) has the highest net margin (Guardant Health (GH) -38.3%, Iqvia Holdings (IQV) 8.1%, BillionToOne (BLLN) 7.6%). On return on invested capital, Iqvia Holdings (IQV) leads (Iqvia Holdings (IQV) 8.2%, BillionToOne (BLLN) 7.0%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Guardant Health (GH) +151.3%, Iqvia Holdings (IQV) +25.0%. Over five years, Guardant Health (GH) compounded fastest (Guardant Health (GH) +8.5%/yr, Iqvia Holdings (IQV) +1.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Iqvia Holdings (IQV) has been the steadiest (Guardant Health (GH) 57.4%, Iqvia Holdings (IQV) 40.3%, BillionToOne (BLLN) 94.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GH, IQV and BLLN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iqvia Holdings (IQV) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.