GH vs ICLR vs IDXG Stock Comparison

Guardant Health, Icon and Interpace Biosciences Prices as of Oct 28, 2026 Peers: Industry group
GH Guardant Health, Inc.
$182.59 +3.0% 1M +162.4% 1Y
Market cap
$24.40B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
4 wins
ICLR Icon Plc
$214.16 +22.0% 1M +20.5% 1Y
Market cap
$16.40B
P/E
37.4x
Revenue (TTM)
$8.23B
Div. yield
–
Contract Research Healthcare
1 win

Head to Head

8 decided of 12

Guardant Health leads on 4 of the 12 questions below (Guardant Health 4, Interpace Biosciences 3, Icon 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGHICLRIDXGLeader
Larger companyMarket capitalisation $24.40B $16.40B $137.12M GH
Cheaper on earningsLower P/E, profitable companies only -53.5x 37.4x 5.6x IDXG
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 20.9x — –
Faster revenue growthRevenue growth, trailing twelve months +42.7% +1.8% -20.5% GH
More profitableNet margin, trailing twelve months -38.3% 5.4% 67.6% IDXG
Better return on capitalReturn on invested capital — 4.7% — –
Less leveragedLower net debt / EBITDA — 2.3x — –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months +162.4% +20.5% +334.2% IDXG
Better 5-year returnAnnualised price return, 5 years +9.4%/yr -5.7%/yr — GH
Less volatileAnnualised volatility, 1 year 57.3% 75.3% 182.0% GH
Higher overall scoreMean of the five percentile scores vs peers 28/100 81/100 66/100 ICLR

Percentile Scorecard

GHICLRIDXG

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGHICLRIDXG
Valuation 18 #76 of 92 100 #1 of 11 59 #38 of 92
Growth 48 #46 of 87 70 #4 of 11 47 #47 of 87
Profitability 7 #80 of 86 80 #3 of 11 92 #8 of 86
Financial Health 53 #46 of 97 75 #4 of 13 67 #33 of 97
Shareholder Returns 15 #47 of 55 – –
Overall 28 81 66
  • GH ranked among 102 companies in Healthcare Providers
  • ICLR ranked among 13 companies in Pharma Services
  • IDXG ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGHICLRIDXGSPY
1 month +3.0%+22.0%-22.9% +0.9%
3 months +26.7%+20.2%+219.4% +5.9%
6 months +118.9%+84.4%+148.7% +8.5%
Year to date +78.8%+17.5%+302.4% +13.3%
1 year +162.4%+20.5%+334.2% +12.4%
3 years +631.5%-9.0%— +88.1%
3 years, per year +94.2%-3.1%— +23.5%
5 years +56.3%-25.3%— +68.2%
5 years, per year +9.4%-5.7%— +11.0%
10 years —+166.6%— +263.4%
10 years, per year —+10.3%— +13.8%

Risk

MeasureGHICLRIDXGSPY
Volatility, 1Y 57.3%75.3%182.0% 12.7%
Downside volatility, 1Y 48.9%87.9%84.2% 12.7%
Beta vs S&P 500, 1Y 1.041.48-0.05 1.00
Return / volatility, 1Y 2.830.271.84 0.98
Max drawdown, 5Y -86.7%-76.9%-81.1% -25.4%
From 52-week high -2.5%0.0%-35.0% -0.9%
52-week high $187.22$214.16$7.62 $779.14
52-week low $69.58$80.08$0.83 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGHICLRIDXG
P/E now vs peer median -53.5xmedian 25.6x 37.4xmedian 37.4x 5.6xmedian 25.6x
P/S now vs peer median 20.6xmedian 1.6x 2.0xmedian 2.7x 3.8xmedian 1.6x
EV/EBITDA now vs peer median -54.1xmedian 16.3x 17.3xmedian 39.5x 28.8xmedian 16.3x
P/FCF now vs peer median -101.3xmedian 21.3x 19.1xmedian 22.1x 33.4xmedian 21.3x
P/B now vs peer median -109.5xmedian 3.3x 1.8xmedian 3.4x 5.9xmedian 3.3x
PEG now vs peer median -5.39median 0.68 -15.76median 2.08 0.18median 0.68

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGHICLRIDXG
Revenue $1.18B $8.23B $36.14M
Gross profit $769.16M $1.93B $23.04M
Operating income -$470.26M $718.25M $4.17M
Net income -$453.44M $448.66M $24.45M
Free cash flow -$240.72M $857.06M $4.10M
R&D $375.79M – $594.00K
EPS (diluted) $-3.41 $5.68 $0.88
Cash & equivalents $1.05B $808.98M $2.70M
Total debt – $3.38B –
Shares (diluted) 132.87M 78.97M 27.71M
Enterprise value $20.46B $13.17B $127.84M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGHICLRIDXG
P/E -53.5x 37.4x 5.6x
P/FCF -101.3x 19.1x 33.4x
P/Operating cash flow -131.7x 16.0x 30.8x
P/S 20.6x 2.0x 3.8x
P/B -109.5x 1.8x 5.9x
P/Tangible book -98.3x 2.7x 5.9x
EV/EBITDA -54.1x 17.3x 28.8x
EV/EBIT -49.6x 26.4x 32.3x
EV/Revenue 19.7x 2.3x 3.7x
EV/FCF -97.0x 22.1x 32.8x
EV/Operating cash flow -126.1x 18.5x 30.2x
PEG (3Y EPS CAGR) -5.39 -15.76 0.18

Growth

14 metrics
MetricGHICLRIDXG
Revenue growth (1Y) 42.7% 1.8% -20.5%
Revenue CAGR (3Y) 32.4% 0.9% -1.0%
Gross profit growth (1Y) 47.7% -13.4% -19.0%
Gross profit CAGR (3Y) – -6.5% -0.1%
Operating income growth (1Y) -2.1% 53.9% -27.2%
Operating income CAGR (3Y) 4.8% -7.0% 46.4%
Net income growth (1Y) -9.6% 55.9% 435.6%
Net income CAGR (3Y) 3.7% -4.4% 54.2%
EPS growth (1Y) -2.4% 30.1% -14.5%
EPS CAGR (3Y) 9.9% -2.4% 31.2%
Operating cash flow growth (1Y) 22.4% -9.9% -11.8%
Operating cash flow CAGR (3Y) 18.1% 15.8% 62.1%
Free cash flow growth (1Y) 11.4% -11.1% -6.8%
Free cash flow CAGR (3Y) 14.4% 18.4% 54.9%

Profitability

14 metrics
MetricGHICLRIDXG
Gross margin 65.0% 23.4% 63.7%
EBITDA margin -36.5% 13.3% 12.9%
Operating margin -39.7% 8.7% 11.5%
Pretax margin -38.4% 6.3% 11.1%
Net margin -38.3% 5.4% 67.6%
FCF margin -20.3% 10.4% 11.4%
Operating cash flow margin -15.7% 12.5% 12.3%
Return on equity – 7.6% 105.5%
Return on assets -23.7% 4.3% 72.0%
Return on invested capital – 4.7% –
Return on capital employed -29.9% 5.3% 14.4%
Asset turnover 0.6x 0.5x 1.1x
Cash conversion (OCF / net income) 0.4x 2.3x 0.2x
Stock comp / revenue 16.2% 1.1% 0.1%

Financial Health

11 metrics
MetricGHICLRIDXG
Debt / assets – 20.8% –
Debt / equity – 0.4x –
Net debt / EBITDA – 2.3x –
Debt / FCF – 3.9x –
Liabilities / assets 111.7% 43.8% 32.7%
Equity / assets -11.7% 56.2% 67.3%
Interest coverage -97.6x 3.4x –
Current ratio 4.0x 1.3x 2.2x
Quick ratio 3.5x 0.9x 1.8x
Cash ratio 3.1x 0.3x 0.5x
Altman Z-score 4.94 2.27 0.42

Shareholder Returns

7 metrics
MetricGHICLRIDXG
Dividend yield – – –
Net buyback yield -1.6% 2.3% –
Shareholder yield -1.6% 2.3% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGHICLRIDXG
Forward P/E – 20.9xFY2026 –
EPS, next fiscal year $-3.33FY2026 $10.25FY2026 $-0.72FY2023
EPS growth, next FY – -18.2%FY2026 –
EPS growth, the year after – +22.2% –
Revenue, next fiscal year $1.42BFY2026 $8.52BFY2026 –
Revenue growth, next FY +44.5%FY2026 +3.2%FY2026 –
Revenue growth, the year after +27.0% -3.2% –

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGHICLRIDXG
Held by institutions 100.0% 100.0% –
Institutions holding 594 422 –
Change in shares held, QoQ -2.6% +5.5% –
Institutions buying 353 233 –
Institutions selling 180 138 –
Buyers to sellers 1.96 1.69 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GHICLRIDXG
GH 1.00 0.21 -0.03
ICLR 0.21 1.00 -0.01
IDXG -0.03 -0.01 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, GH, ICLR and IDXG?

Guardant Health (GH) is the largest by market capitalisation: Guardant Health (GH) $24.40B, Icon (ICLR) $16.40B, Interpace Biosciences (IDXG) $137.12M.

Which stock is cheaper, GH, ICLR and IDXG?

Interpace Biosciences (IDXG) trades on the lowest price-to-earnings ratio (Guardant Health (GH) -53.5x, Icon (ICLR) 37.4x, Interpace Biosciences (IDXG) 5.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Guardant Health (GH) +42.7%, Icon (ICLR) +1.8%, Interpace Biosciences (IDXG) -20.5%.

Which company is more profitable?

Interpace Biosciences (IDXG) has the highest net margin (Guardant Health (GH) -38.3%, Icon (ICLR) 5.4%, Interpace Biosciences (IDXG) 67.6%).

Which stock has performed better?

Over the past year Interpace Biosciences (IDXG) returned the most: Guardant Health (GH) +162.4%, Icon (ICLR) +20.5%, Interpace Biosciences (IDXG) +334.2%. Over five years, Guardant Health (GH) compounded fastest (Guardant Health (GH) +9.4%/yr, Icon (ICLR) -5.7%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Guardant Health (GH) has been the steadiest (Guardant Health (GH) 57.3%, Icon (ICLR) 75.3%, Interpace Biosciences (IDXG) 182.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GH, ICLR and IDXG?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.