GH vs GRAL vs BLLN Stock Comparison

Guardant Health, Grail and BillionToOne Prices as of Nov 5, 2026 Peers: Industry group
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GH Guardant Health, Inc.
$153.43 -10.1% 1M +61.4% 1Y
Market cap
$19.63B
P/E
–
Revenue (TTM)
$1.28B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
GRAL GRAIL, Inc.
$119.13 -13.2% 1M +40.7% 1Y
Market cap
$5.67B
P/E
–
Revenue (TTM)
$159.20M
Div. yield
–
Diagnostic Labs Healthcare
BLLN BillionToOne, Inc.
$112.39 +12.5% 1M
Market cap
$5.25B
P/E
114.2x
Revenue (TTM)
$436.87M
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

6 decided of 12

Guardant Health leads on 3 of the 12 questions below (Guardant Health 3, BillionToOne 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionGHGRALBLLNLeader
Larger companyMarket capitalisation $19.63B $5.67B $5.25B GH
Cheaper on earningsLower P/E, profitable companies only -40.5x -14.0x 114.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 147.9x –
Faster revenue growthRevenue growth, trailing twelve months +41.7% +12.3% +71.9% BLLN
More profitableNet margin, trailing twelve months -37.9% -255.1% 10.5% BLLN
Better return on capitalReturn on invested capital — — 6.9% –
Less leveragedLower net debt / EBITDA — — -9.1x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +61.4% +40.7% — GH
Better 5-year returnAnnualised price return, 5 years +6.8%/yr — — –
Less volatileAnnualised volatility, 1 year 52.8% 113.0% 93.3% GH
Higher overall scoreMean of the five percentile scores vs peers 25/100 37/100 57/100 BLLN

Percentile Scorecard

GHGRALBLLN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisGHGRALBLLN
Valuation 16 #80 of 95 7 #88 of 95 21 #75 of 95
Growth 41 #52 of 88 35 #58 of 88 100 #1 of 88
Profitability 7 #81 of 87 6 #82 of 87 59 #36 of 87
Financial Health 50 #51 of 100 99 #2 of 100 98 #3 of 100
Shareholder Returns 12 #53 of 60 – 7 #56 of 60
Overall 25 37 57
  • GH ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers
  • BLLN ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodGHGRALBLLNSPY
1 month -10.1%-13.2%+12.5% -5.9%
3 months -2.6%+87.9%+22.6% -4.6%
6 months +66.3%+89.3%+21.0% +0.2%
Year to date +50.2%+39.2%+37.3% +7.5%
1 year +61.4%+40.7%— +8.2%
3 years +453.1%—— +68.3%
3 years, per year +76.9%—— +19.0%
5 years +39.2%—— +56.5%
5 years, per year +6.8%—— +9.4%

Risk

MeasureGHGRALBLLNSPY
Volatility, 1Y 52.8%113.0%93.3% 13.6%
Downside volatility, 1Y 51.2%129.2%106.1% 14.2%
Beta vs S&P 500, 1Y 1.302.921.49 1.00
Return / volatility, 1Y 1.160.36— 0.60
Max drawdown, 5Y -85.4%-62.9%-50.8% -25.4%
From 52-week high -18.0%-25.0%-25.1% -5.9%
52-week high $187.22$158.92$149.97 $779.14
52-week low $78.60$43.03$64.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleGHGRALBLLN
P/E now vs peer median -42.5xmedian 24.8x -13.7xmedian 24.8x 115.6xmedian 24.8x
P/S now vs peer median 16.2xmedian 1.6x 33.5xmedian 1.6x 12.3xmedian 1.6x
EV/EBITDA now vs peer median -42.3xmedian 15.9x -10.7xmedian 15.9x 94.0xmedian 15.9x
P/FCF now vs peer median -89.0xmedian 20.9x -17.1xmedian 20.9x 157.9xmedian 20.9x
P/B now vs peer median -74.9xmedian 3.3x 2.2xmedian 3.3x 9.4xmedian 3.3x
PEG now vs peer median -73.30median 0.88 —median 0.88 —median 0.88

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsGHGRALBLLN
Revenue $1.28B $159.20M $436.87M
Gross profit $833.70M $75.17M $311.95M
Operating income -$504.04M -$578.58M $44.69M
Net income -$485.07M -$406.18M $49.39M
Free cash flow -$232.15M -$312.00M $33.91M
R&D $386.67M $188.17M $66.47M
EPS (diluted) $-3.61 $-8.68 $0.86
Cash & equivalents $1.03B $29.00M $561.51M
Total debt – – $89.00M
Shares (diluted) 134.42M 46.78M 53.73M
Enterprise value $15.24B $2.30B $3.10B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricGHGRALBLLN
P/E -42.5x -13.7x 115.6x
P/FCF -89.0x -17.1x 157.9x
P/Operating cash flow -119.1x -17.4x 111.7x
P/S 16.2x 33.5x 12.3x
P/B -74.9x 2.2x 9.4x
P/Tangible book -68.7x 7.5x 9.4x
EV/EBITDA -42.3x -10.7x 94.0x
EV/EBIT -39.0x -7.9x 109.2x
EV/Revenue 15.4x 28.5x 11.2x
EV/FCF -84.6x -14.6x 143.9x
EV/Operating cash flow -113.2x -14.8x 101.9x
PEG (3Y EPS CAGR) -73.30 – –

Growth

14 metrics
MetricGHGRALBLLN
Revenue growth (1Y) 41.7% 12.3% 71.9%
Revenue CAGR (3Y) 33.6% – –
Gross profit growth (1Y) 44.9% 13.1% 88.4%
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) -13.9% -0.7% 844.7%
Operating income CAGR (3Y) 0.6% – –
Net income growth (1Y) -21.6% 0.0% 593.9%
Net income CAGR (3Y) -3.9% – –
EPS growth (1Y) -12.9% 22.8% 193.7%
EPS CAGR (3Y) 0.6% – –
Operating cash flow growth (1Y) 22.2% 6.8% 794.7%
Operating cash flow CAGR (3Y) 19.9% – –
Free cash flow growth (1Y) 11.5% 5.4% 934.5%
Free cash flow CAGR (3Y) 13.9% – –

Profitability

14 metrics
MetricGHGRALBLLN
Gross margin 65.2% 47.2% 71.4%
EBITDA margin -36.3% -267.5% 11.9%
Operating margin -39.4% -363.4% 10.2%
Pretax margin -38.0% -344.3% 11.4%
Net margin -37.9% -255.1% 10.5%
FCF margin -18.2% -196.0% 7.8%
Operating cash flow margin -13.6% -192.4% 11.0%
Return on equity – -16.3% 9.0%
Return on assets -25.5% -14.6% 6.6%
Return on invested capital – – 6.9%
Return on capital employed -33.0% -21.5% 6.5%
Asset turnover 0.7x 0.1x 0.6x
Cash conversion (OCF / net income) 0.4x 0.8x 1.0x
Stock comp / revenue 16.5% 40.3% 7.0%

Financial Health

11 metrics
MetricGHGRALBLLN
Debt / assets – – 11.7%
Debt / equity – – 0.2x
Net debt / EBITDA – – -9.1x
Debt / FCF – – 2.6x
Liabilities / assets 114.6% 10.1% 25.5%
Equity / assets -14.6% 89.9% 74.5%
Interest coverage -96.6x – 1,655x
Current ratio 3.6x 8.9x 11.2x
Quick ratio 3.3x 8.6x 10.7x
Cash ratio 2.8x 8.4x 9.3x
Altman Z-score 3.66 5.84 17.88

Shareholder Returns

7 metrics
MetricGHGRALBLLN
Dividend yield – – –
Net buyback yield -2.0% – -5.7%
Shareholder yield -2.0% – -5.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusGHGRALBLLN
Forward P/E – – 147.9xFY2026
EPS, next fiscal year $-3.33FY2026 $-9.05FY2026 $0.76FY2026
EPS growth, next FY – – +442.9%FY2026
EPS growth, the year after – – +22.4%
Revenue, next fiscal year $1.42BFY2026 $169.78MFY2026 $481.76MFY2026
Revenue growth, next FY +44.5%FY2026 +15.4%FY2026 +57.9%FY2026
Revenue growth, the year after +27.0% +38.2% +27.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersGHGRALBLLN
Held by institutions 100.0% 85.4% 32.6%
Institutions holding 597 374 155
Change in shares held, QoQ -2.5% +8.4% +34.7%
Institutions buying 356 183 127
Institutions selling 180 101 13
Buyers to sellers 1.98 1.81 9.77

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

GHGRALBLLN
GH 1.00 0.46 0.30
GRAL 0.46 1.00 0.35
BLLN 0.30 0.35 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, GH, GRAL and BLLN?

Guardant Health (GH) is the largest by market capitalisation: Guardant Health (GH) $19.63B, Grail (GRAL) $5.67B, BillionToOne (BLLN) $5.25B.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: Guardant Health (GH) +41.7%, Grail (GRAL) +12.3%, BillionToOne (BLLN) +71.9%.

Which company is more profitable?

BillionToOne (BLLN) has the highest net margin (Guardant Health (GH) -37.9%, Grail (GRAL) -255.1%, BillionToOne (BLLN) 10.5%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Guardant Health (GH) +61.4%, Grail (GRAL) +40.7%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Guardant Health (GH) has been the steadiest (Guardant Health (GH) 52.8%, Grail (GRAL) 113.0%, BillionToOne (BLLN) 93.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, GH, GRAL and BLLN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 3. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.