FTRE vs CRL vs DNA Stock Comparison

Fortrea Holdings, Charles River Laboratories International and Ginkgo Bioworks Holdings Prices as of Oct 27, 2026 Peers: Industry group
FTRE Fortrea Holdings Inc.
$24.43 +22.8% 1M +135.1% 1Y
Market cap
$2.45B
P/E
–
Revenue (TTM)
$2.68B
Div. yield
–
Contract Research Healthcare
4 wins

Head to Head

10 decided of 12

Charles River Laboratories International leads on 6 of the 12 questions below (Charles River Laboratories International 6, Fortrea Holdings 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionFTRECRLDNALeader
Larger companyMarket capitalisation $2.45B $17.99B $832.69M CRL
Cheaper on earningsLower P/E, profitable companies only -28.7x -75.5x -2.9x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 30.2x 32.9x — FTRE
Faster revenue growthRevenue growth, trailing twelve months -2.1% -0.7% -46.8% CRL
More profitableNet margin, trailing twelve months -3.2% -6.0% -260.0% FTRE
Better return on capitalReturn on invested capital -0.7% 1.6% — CRL
Less leveragedLower net debt / EBITDA 13.1x 6.3x — CRL
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +135.1% +83.9% -15.8% FTRE
Better 5-year returnAnnualised price return, 5 years — -3.9%/yr -54.4%/yr CRL
Less volatileAnnualised volatility, 1 year 70.3% 45.9% 101.5% CRL
Higher overall scoreMean of the five percentile scores vs peers 50/100 45/100 43/100 FTRE

Percentile Scorecard

FTRECRLDNA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisFTRECRLDNA
Valuation 90 #2 of 11 60 #5 of 11 10 #10 of 11
Growth 60 #5 of 11 10 #10 of 11 50 #6 of 11
Profitability 50 #6 of 11 70 #4 of 11 10 #10 of 11
Financial Health 0 #13 of 13 42 #8 of 13 100 #1 of 13
Shareholder Returns – – –
Overall 50 45 43
  • FTRE ranked among 13 companies in Pharma Services
  • CRL ranked among 13 companies in Pharma Services
  • DNA ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodFTRECRLDNASPY
1 month +22.8%+22.5%+5.7% -0.2%
3 months +18.0%+49.4%+46.4% +3.9%
6 months +127.0%+115.3%+43.6% +8.2%
Year to date +41.6%+80.0%+35.6% +12.9%
1 year +135.1%+83.9%-15.8% +12.3%
3 years -11.3%+108.0%-79.1% +87.4%
3 years, per year -3.9%+27.7%-40.7% +23.3%
5 years —-18.2%-98.0% +67.9%
5 years, per year —-3.9%-54.4% +10.9%
10 years —+369.5%— +261.1%
10 years, per year —+16.7%— +13.7%

Risk

MeasureFTRECRLDNASPY
Volatility, 1Y 70.3%45.9%101.5% 12.7%
Downside volatility, 1Y 63.6%43.0%103.1% 12.7%
Beta vs S&P 500, 1Y 2.011.273.03 1.00
Return / volatility, 1Y 1.921.83-0.16 0.97
Max drawdown, 5Y -89.9%-77.8%-99.1% -25.4%
From 52-week high 0.0%0.0%-24.8% -1.2%
52-week high $24.43$359.04$14.98 $779.14
52-week low $8.87$149.93$5.48 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleFTRECRLDNA
P/E now vs peer median -27.2xmedian 32.1x -72.3xmedian 32.1x -2.4xmedian 32.1x
P/S now vs peer median 0.9xmedian 2.6x 4.3xmedian 2.6x 6.4xmedian 2.6x
EV/EBITDA now vs peer median 47.5xmedian 38.1x 50.4xmedian 38.1x -2.7xmedian 38.1x
P/FCF now vs peer median 11.9xmedian 21.5x 46.2xmedian 21.5x -4.1xmedian 21.5x
P/B now vs peer median 4.4xmedian 3.1x 6.0xmedian 3.1x 1.7xmedian 3.1x
PEG now vs peer median 0.57median 2.03 2.00median 2.03 0.02median 2.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsFTRECRLDNA
Revenue $2.68B $4.00B $111.86M
Gross profit $516.60M $1.31B $92.92M
Operating income -$10.80M $90.14M -$290.69M
Net income -$85.20M -$239.23M -$290.80M
Free cash flow $196.00M $370.61M -$174.80M
R&D – – $215.61M
EPS (diluted) $-0.90 $-4.97 $-5.24
Cash & equivalents $168.60M $192.03M $84.54M
Total debt $1.05B $2.62B –
Shares (diluted) 94.80M 48.02M 55.46M
Enterprise value $1.83B $17.19B $70.60M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricFTRECRLDNA
P/E -27.2x -72.3x -2.4x
P/FCF 11.9x 46.2x -4.1x
P/Operating cash flow 10.2x 29.4x -4.2x
P/S 0.9x 4.3x 6.4x
P/B 4.4x 6.0x 1.7x
P/Tangible book -37.1x 6.6x 1.9x
EV/EBITDA 47.5x 50.4x -2.7x
EV/EBIT -297.1x 217.0x -2.2x
EV/Revenue 1.2x 4.9x 5.7x
EV/FCF 16.4x 52.8x -3.6x
EV/Operating cash flow 14.1x 33.6x -3.7x
PEG (3Y EPS CAGR) 0.57 2.00 0.02

Growth

14 metrics
MetricFTRECRLDNA
Revenue growth (1Y) -2.1% -0.7% -46.8%
Revenue CAGR (3Y) -0.1% -1.5% -30.0%
Gross profit growth (1Y) -4.2% -0.1% -49.3%
Gross profit CAGR (3Y) -10.2% -5.5% -28.2%
Operating income growth (1Y) 98.8% -27.6% 2.4%
Operating income CAGR (3Y) -27.7% -48.2% 39.1%
Net income growth (1Y) 91.7% -268.7% 7.7%
Net income CAGR (3Y) -38.4% -35.5% 38.0%
EPS growth (1Y) 92.1% -253.8% 8.7%
EPS CAGR (3Y) -47.7% -36.2% -102.3%
Operating cash flow growth (1Y) 359.7% -26.1% 28.4%
Operating cash flow CAGR (3Y) -3.4% -2.3% 16.9%
Free cash flow growth (1Y) 290.1% -35.9% 36.2%
Free cash flow CAGR (3Y) 0.8% 8.6% 22.1%

Profitability

14 metrics
MetricFTRECRLDNA
Gross margin 19.3% 32.7% 83.1%
EBITDA margin 2.5% 9.7% -211.6%
Operating margin -0.4% 2.3% -259.9%
Pretax margin -2.9% -4.6% -264.1%
Net margin -3.2% -6.0% -260.0%
FCF margin 7.3% 9.3% -156.3%
Operating cash flow margin 8.5% 14.6% -152.2%
Return on equity -16.2% -8.2% -67.4%
Return on assets -3.2% -3.1% -28.7%
Return on invested capital -0.7% 1.6% –
Return on capital employed -0.6% 1.4% -31.0%
Asset turnover 1.0x 0.5x 0.1x
Cash conversion (OCF / net income) -2.7x -2.4x 0.6x
Stock comp / revenue 2.3% 2.1% 61.5%

Financial Health

11 metrics
MetricFTRECRLDNA
Debt / assets 38.8% 34.8% –
Debt / equity 2.0x 0.9x –
Net debt / EBITDA 13.1x 6.3x –
Debt / FCF 5.4x 7.1x –
Liabilities / assets 80.7% 62.2% 57.5%
Equity / assets 19.3% 37.8% 42.5%
Interest coverage – 0.8x –
Current ratio 1.0x 1.3x 4.6x
Quick ratio 0.9x 0.8x 1.4x
Cash ratio 0.2x 0.2x 1.2x
Altman Z-score 0.86 3.08 -8.66

Shareholder Returns

7 metrics
MetricFTRECRLDNA
Dividend yield – – –
Net buyback yield – 1.9% –
Shareholder yield – 1.9% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusFTRECRLDNA
Forward P/E 30.2xFY2026 32.9xFY2026 –
EPS, next fiscal year $0.81FY2026 $10.90FY2026 $-4.06FY2026
EPS growth, next FY +88.4%FY2026 +6.0%FY2026 –
EPS growth, the year after +22.2% +20.5% –
Revenue, next fiscal year $2.77BFY2026 $3.82BFY2026 $88.21MFY2026
Revenue growth, next FY +1.7%FY2026 -4.9%FY2026 -48.2%FY2026
Revenue growth, the year after -3.4% +0.7% +5.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersFTRECRLDNA
Held by institutions 100.0% 100.0% 55.2%
Institutions holding 329 570 182
Change in shares held, QoQ -0.2% -0.7% +12.3%
Institutions buying 139 270 100
Institutions selling 108 204 39
Buyers to sellers 1.29 1.32 2.56

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

FTRECRLDNA
FTRE 1.00 0.55 0.31
CRL 0.55 1.00 0.34
DNA 0.31 0.34 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, FTRE, CRL and DNA?

Charles River Laboratories International (CRL) is the largest by market capitalisation: Fortrea Holdings (FTRE) $2.45B, Charles River Laboratories International (CRL) $17.99B, Ginkgo Bioworks Holdings (DNA) $832.69M.

Which company is growing faster?

Charles River Laboratories International (CRL) grew revenue fastest over the trailing twelve months: Fortrea Holdings (FTRE) -2.1%, Charles River Laboratories International (CRL) -0.7%, Ginkgo Bioworks Holdings (DNA) -46.8%.

Which company is more profitable?

Fortrea Holdings (FTRE) has the highest net margin (Fortrea Holdings (FTRE) -3.2%, Charles River Laboratories International (CRL) -6.0%, Ginkgo Bioworks Holdings (DNA) -260.0%). On return on invested capital, Charles River Laboratories International (CRL) leads (Fortrea Holdings (FTRE) -0.7%, Charles River Laboratories International (CRL) 1.6%).

Which stock has performed better?

Over the past year Fortrea Holdings (FTRE) returned the most: Fortrea Holdings (FTRE) +135.1%, Charles River Laboratories International (CRL) +83.9%, Ginkgo Bioworks Holdings (DNA) -15.8%. Over five years, Charles River Laboratories International (CRL) compounded fastest (Charles River Laboratories International (CRL) -3.9%/yr, Ginkgo Bioworks Holdings (DNA) -54.4%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Charles River Laboratories International (CRL) has been the steadiest (Fortrea Holdings (FTRE) 70.3%, Charles River Laboratories International (CRL) 45.9%, Ginkgo Bioworks Holdings (DNA) 101.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, FTRE, CRL and DNA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Charles River Laboratories International (CRL) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.