FENC vs ALVO vs AMPH Stock Comparison

Fennec Pharmaceuticals, Alvotech and Amphastar Pharmaceuticals Prices as of Oct 26, 2026 Peers: Industry group
ALVO Alvotech
$4.62 -19.7% 1M -45.0% 1Y
Market cap
$1.36B
P/E
–
Revenue (TTM)
$105.94M
Div. yield
–
Generic Drugs Healthcare
1 win

Head to Head

10 decided of 12

Amphastar Pharmaceuticals leads on 6 of the 12 questions below (Amphastar Pharmaceuticals 6, Fennec Pharmaceuticals 3, Alvotech 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionFENCALVOAMPHLeader
Larger companyMarket capitalisation $365.49M $1.36B $1.12B ALVO
Cheaper on earningsLower P/E, profitable companies only -55.3x -5.2x 14.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 35.0x — 8.2x AMPH
Faster revenue growthRevenue growth, trailing twelve months +61.4% -74.3% +1.0% FENC
More profitableNet margin, trailing twelve months -12.3% -248.0% 10.8% AMPH
Better return on capitalReturn on invested capital — 4.4% 6.4% AMPH
Less leveragedLower net debt / EBITDA — 13.1x 1.8x AMPH
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +12.9% -45.0% +3.9% FENC
Better 5-year returnAnnualised price return, 5 years +2.3%/yr -14.1%/yr +6.8%/yr AMPH
Less volatileAnnualised volatility, 1 year 64.1% 81.8% 54.3% AMPH
Higher overall scoreMean of the five percentile scores vs peers 73/100 47/100 73/100 FENC

Percentile Scorecard

FENCALVOAMPH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisFENCALVOAMPH
Valuation 59 #255 of 626 72 #178 of 626 99 #8 of 626
Growth 93 #43 of 604 35 #396 of 604 43 #347 of 604
Profitability 84 #88 of 555 68 #177 of 555 87 #72 of 555
Financial Health 57 #285 of 658 15 #557 of 658 37 #412 of 658
Shareholder Returns – – 99 #4 of 368
Overall 73 47 73
  • FENC ranked among 673 companies in Pharmaceuticals and Biotechnology
  • ALVO ranked among 673 companies in Pharmaceuticals and Biotechnology
  • AMPH ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodFENCALVOAMPHSPY
1 month -4.2%-19.7%-2.5% -0.8%
3 months -0.6%+50.0%+32.8% +3.5%
6 months +48.2%+40.0%+17.6% +7.0%
Year to date +31.8%-9.9%-4.9% +12.2%
1 year +12.9%-45.0%+3.9% +13.0%
3 years +48.4%-48.6%-42.9% +86.3%
3 years, per year +14.1%-19.9%-17.1% +23.1%
5 years +12.2%-53.3%+38.7% +68.6%
5 years, per year +2.3%-14.1%+6.8% +11.0%
10 years +415.2%—+40.1% +258.0%
10 years, per year +17.8%—+3.4% +13.6%

Risk

MeasureFENCALVOAMPHSPY
Volatility, 1Y 64.1%81.8%54.3% 12.7%
Downside volatility, 1Y 59.6%86.1%66.4% 12.7%
Beta vs S&P 500, 1Y 1.320.730.58 1.00
Return / volatility, 1Y 0.20-0.550.07 1.02
Max drawdown, 5Y -65.6%-82.6%-74.0% -25.4%
From 52-week high -20.6%-43.2%-13.4% -1.8%
52-week high $12.78$8.13$29.40 $779.14
52-week low $5.77$3.00$16.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleFENCALVOAMPH
P/E now vs peer median -53.1xmedian 17.1x -5.1xmedian 17.1x 14.2xmedian 17.1x
P/S now vs peer median 6.6xmedian 8.8x 13.6xmedian 8.8x 1.5xmedian 8.8x
EV/EBITDA now vs peer median —median 17.1x 29.3xmedian 17.1x 8.0xmedian 17.1x
P/FCF now vs peer median —median 18.0x -5.5xmedian 18.0x 7.1xmedian 18.0x
P/B now vs peer median 8.4xmedian 2.1x -7.5xmedian 2.1x 1.4xmedian 2.1x
PEG now vs peer median -1.25median 0.31 -0.21median 0.31 -5.53median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsFENCALVOAMPH
Revenue $53.77M $105.94M $730.02M
Gross profit $49.65M $7.66M $348.11M
Operating income -$3.74M $47.54M $114.29M
Net income -$6.60M -$179.60M $78.55M
Free cash flow – -$261.39M $152.89M
R&D $274.00K $46.37M $94.57M
EPS (diluted) $-0.18 $-0.90 $1.78
Cash & equivalents $41.25M $142.80M $223.61M
Total debt – $1.31B $612.05M
Shares (diluted) 36.43M 291.34M 44.23M
Enterprise value $246.80M $929.80M -$25.55M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricFENCALVOAMPH
P/E -53.1x -5.1x 14.2x
P/FCF – -5.5x 7.1x
P/Operating cash flow – -7.3x 5.9x
P/S 6.6x 13.6x 1.5x
P/B 8.4x -7.5x 1.4x
P/Tangible book 8.4x -4.3x 1.5x
EV/EBITDA – 29.3x 8.0x
EV/EBIT -84.1x 54.8x 12.3x
EV/Revenue 5.8x 24.6x 1.9x
EV/FCF – -10.0x 9.2x
EV/Operating cash flow – -13.1x 7.6x
PEG (3Y EPS CAGR) -1.25 -0.21 -5.53

Growth

14 metrics
MetricFENCALVOAMPH
Revenue growth (1Y) 61.4% -74.3% 1.0%
Revenue CAGR (3Y) 118.1% 104.2% 10.5%
Gross profit growth (1Y) 65.9% -95.0% -3.4%
Gross profit CAGR (3Y) – 27.6% 8.0%
Operating income growth (1Y) 61.4% -13.3% -37.1%
Operating income CAGR (3Y) 46.2% 28.9% -4.5%
Net income growth (1Y) 45.1% -383.6% -41.7%
Net income CAGR (3Y) 37.0% 24.4% -8.3%
EPS growth (1Y) 58.3% -481.6% -36.5%
EPS CAGR (3Y) 42.6% 24.6% -2.6%
Operating cash flow growth (1Y) – -367.1% 15.6%
Operating cash flow CAGR (3Y) – 12.8% 12.1%
Free cash flow growth (1Y) – -113.0% 36.3%
Free cash flow CAGR (3Y) – 8.6% 15.0%

Profitability

14 metrics
MetricFENCALVOAMPH
Gross margin 92.4% 7.2% 47.7%
EBITDA margin – 83.9% 23.9%
Operating margin -7.0% 44.9% 15.7%
Pretax margin -8.2% -62.1% 14.0%
Net margin -12.3% -248.0% 10.8%
FCF margin – -246.7% 20.9%
Operating cash flow margin – -187.6% 25.3%
Return on equity -11.4% – 10.2%
Return on assets -6.1% -17.5% 4.6%
Return on invested capital – 4.4% 6.4%
Return on capital employed -6.2% 4.1% 8.0%
Asset turnover 0.7x 0.1x 0.4x
Cash conversion (OCF / net income) – 1.1x 2.4x
Stock comp / revenue 14.8% 8.7% 4.0%

Financial Health

11 metrics
MetricFENCALVOAMPH
Debt / assets – 82.3% 35.1%
Debt / equity – -6.8x 0.8x
Net debt / EBITDA – 13.1x 1.8x
Debt / FCF – -5.0x 4.0x
Liabilities / assets 44.0% 112.1% 55.9%
Equity / assets 56.0% -12.1% 44.1%
Interest coverage -2.5x 0.8x 4.4x
Current ratio 5.8x 1.6x 2.4x
Quick ratio 5.2x 1.1x 1.7x
Cash ratio 3.3x 0.4x 1.1x
Altman Z-score 3.70 -1.37 2.12

Shareholder Returns

7 metrics
MetricFENCALVOAMPH
Dividend yield – – –
Net buyback yield – – 9.0%
Shareholder yield – – 9.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusFENCALVOAMPH
Forward P/E 35.0xFY2026 – 8.2xFY2026
EPS, next fiscal year $0.29FY2026 $-0.01FY2026 $3.09FY2026
EPS growth, next FY – – -4.9%FY2026
EPS growth, the year after +241.4% – +9.4%
Revenue, next fiscal year $75.58MFY2026 $556.32MFY2026 $790.23MFY2026
Revenue growth, next FY +69.3%FY2026 -6.2%FY2026 +9.8%FY2026
Revenue growth, the year after +28.3% +23.2% -5.4%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersFENCALVOAMPH
Held by institutions 46.6% 14.7% 64.8%
Institutions holding 107 72 209
Change in shares held, QoQ +0.7% +152.4% -11.7%
Institutions buying 71 44 96
Institutions selling 19 17 74
Buyers to sellers 3.74 2.59 1.30

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

FENCALVOAMPH
FENC 1.00 0.06 0.08
ALVO 0.06 1.00 0.11
AMPH 0.08 0.11 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, FENC, ALVO and AMPH?

Alvotech (ALVO) is the largest by market capitalisation: Fennec Pharmaceuticals (FENC) $365.49M, Alvotech (ALVO) $1.36B, Amphastar Pharmaceuticals (AMPH) $1.12B.

Which company is growing faster?

Fennec Pharmaceuticals (FENC) grew revenue fastest over the trailing twelve months: Fennec Pharmaceuticals (FENC) +61.4%, Alvotech (ALVO) -74.3%, Amphastar Pharmaceuticals (AMPH) +1.0%.

Which company is more profitable?

Amphastar Pharmaceuticals (AMPH) has the highest net margin (Fennec Pharmaceuticals (FENC) -12.3%, Alvotech (ALVO) -248.0%, Amphastar Pharmaceuticals (AMPH) 10.8%). On return on invested capital, Amphastar Pharmaceuticals (AMPH) leads (Alvotech (ALVO) 4.4%, Amphastar Pharmaceuticals (AMPH) 6.4%).

Which stock has performed better?

Over the past year Fennec Pharmaceuticals (FENC) returned the most: Fennec Pharmaceuticals (FENC) +12.9%, Alvotech (ALVO) -45.0%, Amphastar Pharmaceuticals (AMPH) +3.9%. Over five years, Amphastar Pharmaceuticals (AMPH) compounded fastest (Fennec Pharmaceuticals (FENC) +2.3%/yr, Alvotech (ALVO) -14.1%/yr, Amphastar Pharmaceuticals (AMPH) +6.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Amphastar Pharmaceuticals (AMPH) has been the steadiest (Fennec Pharmaceuticals (FENC) 64.1%, Alvotech (ALVO) 81.8%, Amphastar Pharmaceuticals (AMPH) 54.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, FENC, ALVO and AMPH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Amphastar Pharmaceuticals (AMPH) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.