DNA vs MEDP vs LDOS Stock Comparison

Ginkgo Bioworks Holdings, Medpace Holdings and Leidos Holdings Prices as of Oct 28, 2026 Peers: Industry group
MEDP Medpace Holdings, Inc.
$692.68 +12.5% 1M +19.3% 1Y
Market cap
$19.37B
P/E
37.4x
Revenue (TTM)
$2.84B
Div. yield
–
Contract Research Healthcare
6 wins
LDOS Leidos Holdings, Inc.
$139.62 +14.1% 1M -25.7% 1Y
Market cap
$17.52B
P/E
12.8x
Revenue (TTM)
$17.63B
Div. yield
1.23%
Defense Industrials
3 wins

Head to Head

9 decided of 12

Medpace Holdings leads on 6 of the 12 questions below (Medpace Holdings 6, Leidos Holdings 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNAMEDPLDOSLeader
Larger companyMarket capitalisation $850.54M $19.37B $17.52B MEDP
Cheaper on earningsLower P/E, profitable companies only -2.9x 37.4x 12.8x LDOS
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 38.9x 11.0x LDOS
Faster revenue growthRevenue growth, trailing twelve months -46.8% +20.4% +3.4% MEDP
More profitableNet margin, trailing twelve months -260.0% 18.2% 7.8% MEDP
Better return on capitalReturn on invested capital — — 13.9% –
Less leveragedLower net debt / EBITDA — — 2.3x –
Higher dividend yieldTrailing dividend yield — — 1.23% –
Better 1-year returnPrice return, last 12 months +4.8% +19.3% -25.7% MEDP
Better 5-year returnAnnualised price return, 5 years -52.5%/yr +25.1%/yr +6.9%/yr MEDP
Less volatileAnnualised volatility, 1 year 102.8% 45.5% 35.6% LDOS
Higher overall scoreMean of the five percentile scores vs peers 43/100 78/100 70/100 MEDP

Percentile Scorecard

DNAMEDPLDOS

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNAMEDPLDOS
Valuation 10 #10 of 11 60 #5 of 11 98 #3 of 100
Growth 50 #6 of 11 100 #1 of 11 58 #41 of 97
Profitability 10 #10 of 11 100 #1 of 11 86 #14 of 96
Financial Health 100 #1 of 13 50 #7 of 13 32 #72 of 105
Shareholder Returns – – 73 #18 of 65
Overall 43 78 70
  • DNA ranked among 13 companies in Pharma Services
  • MEDP ranked among 13 companies in Pharma Services
  • LDOS ranked among 107 companies in Aerospace and Defense

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNAMEDPLDOSSPY
1 month +27.8%+12.5%+14.1% +0.9%
3 months +75.4%+18.4%+22.1% +5.9%
6 months +78.0%+67.5%-4.3% +8.5%
Year to date +60.6%+23.3%-22.6% +13.3%
1 year +4.8%+19.3%-25.7% +12.4%
3 years -75.3%+176.8%+54.3% +88.1%
3 years, per year -37.3%+40.4%+15.6% +23.5%
5 years -97.6%+205.8%+39.6% +68.2%
5 years, per year -52.5%+25.1%+6.9% +11.0%
10 years —+2,297.6%+237.2% +263.4%
10 years, per year —+37.4%+12.9% +13.8%

Risk

MeasureDNAMEDPLDOSSPY
Volatility, 1Y 102.8%45.5%35.6% 12.7%
Downside volatility, 1Y 103.3%54.1%37.1% 12.7%
Beta vs S&P 500, 1Y 3.060.680.26 1.00
Return / volatility, 1Y 0.050.42-0.72 0.98
Max drawdown, 5Y -99.1%-42.9%-50.3% -25.4%
From 52-week high -10.9%0.0%-30.0% -0.9%
52-week high $14.98$692.68$199.55 $779.14
52-week low $5.48$393.42$100.00 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNAMEDPLDOS
P/E now vs peer median -2.9xmedian 37.4x 37.4xmedian 37.4x 12.8xmedian 26.4x
P/S now vs peer median 7.6xmedian 2.7x 6.8xmedian 2.7x 1.0xmedian 3.0x
EV/EBITDA now vs peer median -3.2xmedian 39.5x 29.4xmedian 39.5x 9.8xmedian 14.5x
P/FCF now vs peer median -4.9xmedian 22.1x 29.0xmedian 22.1x 8.1xmedian 26.1x
P/B now vs peer median 2.0xmedian 3.4x 33.1xmedian 3.4x 3.3xmedian 2.5x
PEG now vs peer median 0.03median 2.08 1.31median 2.08 0.45median 0.90

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNAMEDPLDOS
Revenue $111.86M $2.84B $17.63B
Gross profit $92.92M $827.16M $3.14B
Operating income -$290.69M $607.14M $2.03B
Net income -$290.80M $517.83M $1.40B
Free cash flow -$174.80M $667.63M $2.16B
R&D $215.61M – –
EPS (diluted) $-5.24 $18.25 $10.92
Cash & equivalents $84.54M $705.32M $748.00M
Total debt – – $21.66B
Shares (diluted) 55.46M 28.37M 126.00M
Enterprise value $88.46M $17.01B $14.29B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNAMEDPLDOS
P/E -2.9x 37.4x 12.8x
P/FCF -4.9x 29.0x 8.1x
P/Operating cash flow -5.0x 26.8x 7.6x
P/S 7.6x 6.8x 1.0x
P/B 2.0x 33.1x 3.3x
P/Tangible book 2.3x 35.1x 4.0x
EV/EBITDA -3.2x 29.4x 9.8x
EV/EBIT -2.6x 30.7x 11.2x
EV/Revenue 6.8x 6.6x 1.3x
EV/FCF -4.4x 28.0x 10.5x
EV/Operating cash flow -4.5x 25.8x 9.9x
PEG (3Y EPS CAGR) 0.03 1.31 0.45

Growth

14 metrics
MetricDNAMEDPLDOS
Revenue growth (1Y) -46.8% 20.4% 3.4%
Revenue CAGR (3Y) -30.0% 16.8% 5.9%
Gross profit growth (1Y) -49.3% 12.8% 4.8%
Gross profit CAGR (3Y) -28.2% 18.0% 14.4%
Operating income growth (1Y) 2.4% 19.7% -0.4%
Operating income CAGR (3Y) 39.1% 23.0% 21.1%
Net income growth (1Y) 7.7% 19.6% -0.8%
Net income CAGR (3Y) 38.0% 23.8% 24.8%
EPS growth (1Y) 8.7% 21.5% 1.3%
EPS CAGR (3Y) -102.3% 28.5% 28.6%
Operating cash flow growth (1Y) 28.4% 1.7% 54.9%
Operating cash flow CAGR (3Y) 16.9% 20.5% 35.7%
Free cash flow growth (1Y) 36.2% -1.4% 63.2%
Free cash flow CAGR (3Y) 22.1% 20.9% 41.7%

Profitability

14 metrics
MetricDNAMEDPLDOS
Gross margin 83.1% 29.1% 17.8%
EBITDA margin -211.6% 22.4% 13.2%
Operating margin -259.9% 21.4% 11.5%
Pretax margin -264.1% 22.1% 10.2%
Net margin -260.0% 18.2% 7.8%
FCF margin -156.3% 23.5% 12.3%
Operating cash flow margin -152.2% 25.5% 13.0%
Return on equity -67.4% 101.7% 26.8%
Return on assets -28.7% 23.8% 9.0%
Return on invested capital – – 13.9%
Return on capital employed -31.0% 88.8% 16.5%
Asset turnover 0.1x 1.3x 1.1x
Cash conversion (OCF / net income) 0.6x 1.4x 1.6x
Stock comp / revenue 61.5% 0.8% 0.6%

Financial Health

11 metrics
MetricDNAMEDPLDOS
Debt / assets – – 38.6%
Debt / equity – – 1.1x
Net debt / EBITDA – – 2.3x
Debt / FCF – – 2.8x
Liabilities / assets 57.5% 74.6% 65.9%
Equity / assets 42.5% 25.4% 34.1%
Interest coverage – – –
Current ratio 4.6x 0.8x 1.6x
Quick ratio 1.4x 0.8x 1.4x
Cash ratio 1.2x 0.5x 0.2x
Altman Z-score -8.53 8.51 3.20

Shareholder Returns

7 metrics
MetricDNAMEDPLDOS
Dividend yield – – 1.2%
Net buyback yield – 1.3% 3.8%
Shareholder yield – 1.3% 5.0%
Payout ratio (earnings) – – 15.5%
Payout ratio (FCF) – – 10.0%
Dividend growth (1Y) – – 3.3%
Dividend CAGR (3Y) – – 2.8%

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNAMEDPLDOS
Forward P/E – 38.9xFY2026 11.0xFY2026
EPS, next fiscal year $-4.06FY2026 $17.80FY2026 $12.75FY2026
EPS growth, next FY – +16.5%FY2026 +6.3%FY2026
EPS growth, the year after – +6.2% -9.0%
Revenue, next fiscal year $88.21MFY2026 $2.94BFY2026 $17.52BFY2026
Revenue growth, next FY -48.2%FY2026 +16.4%FY2026 +2.0%FY2026
Revenue growth, the year after +5.8% +6.0% +14.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNAMEDPLDOS
Held by institutions 55.2% 87.8% 79.3%
Institutions holding 182 693 773
Change in shares held, QoQ +12.3% +3.2% +4.1%
Institutions buying 100 279 380
Institutions selling 39 302 294
Buyers to sellers 2.56 0.92 1.29

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNAMEDPLDOS
DNA 1.00 0.30 0.09
MEDP 0.30 1.00 0.14
LDOS 0.09 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, MEDP and LDOS?

Medpace Holdings (MEDP) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $850.54M, Medpace Holdings (MEDP) $19.37B, Leidos Holdings (LDOS) $17.52B.

Which stock is cheaper, DNA, MEDP and LDOS?

Leidos Holdings (LDOS) trades on the lowest price-to-earnings ratio (Ginkgo Bioworks Holdings (DNA) -2.9x, Medpace Holdings (MEDP) 37.4x, Leidos Holdings (LDOS) 12.8x). On next year's consensus earnings, Leidos Holdings (LDOS) is cheapest (Medpace Holdings (MEDP) 38.9x, Leidos Holdings (LDOS) 11.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Medpace Holdings (MEDP) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Medpace Holdings (MEDP) +20.4%, Leidos Holdings (LDOS) +3.4%.

Which company is more profitable?

Medpace Holdings (MEDP) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Medpace Holdings (MEDP) 18.2%, Leidos Holdings (LDOS) 7.8%).

Which stock has performed better?

Over the past year Medpace Holdings (MEDP) returned the most: Ginkgo Bioworks Holdings (DNA) +4.8%, Medpace Holdings (MEDP) +19.3%, Leidos Holdings (LDOS) -25.7%. Over five years, Medpace Holdings (MEDP) compounded fastest (Ginkgo Bioworks Holdings (DNA) -52.5%/yr, Medpace Holdings (MEDP) +25.1%/yr, Leidos Holdings (LDOS) +6.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Leidos Holdings (LDOS) 1.23%. Ginkgo Bioworks Holdings (DNA) and Medpace Holdings (MEDP) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Leidos Holdings (LDOS) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 102.8%, Medpace Holdings (MEDP) 45.5%, Leidos Holdings (LDOS) 35.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, MEDP and LDOS?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Medpace Holdings (MEDP) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.