DNA vs MEDP vs GH Stock Comparison

Ginkgo Bioworks Holdings, Medpace Holdings and Guardant Health Prices as of Oct 27, 2026 Peers: Industry group
MEDP Medpace Holdings, Inc.
$673.79 +8.9% 1M +13.0% 1Y
Market cap
$19.28B
P/E
37.2x
Revenue (TTM)
$2.84B
Div. yield
–
Contract Research Healthcare
4 wins
GH Guardant Health, Inc.
$178.06 +0.5% 1M +151.3% 1Y
Market cap
$24.31B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

7 decided of 12

Medpace Holdings leads on 4 of the 12 questions below (Medpace Holdings 4, Guardant Health 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNAMEDPGHLeader
Larger companyMarket capitalisation $832.69M $19.28B $24.31B GH
Cheaper on earningsLower P/E, profitable companies only -2.9x 37.2x -53.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 37.9x — –
Faster revenue growthRevenue growth, trailing twelve months -46.8% +20.4% +42.7% GH
More profitableNet margin, trailing twelve months -260.0% 18.2% -38.3% MEDP
Better return on capitalReturn on invested capital — — — –
Less leveragedLower net debt / EBITDA — — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -15.8% +13.0% +151.3% GH
Better 5-year returnAnnualised price return, 5 years -54.4%/yr +25.1%/yr +8.5%/yr MEDP
Less volatileAnnualised volatility, 1 year 101.5% 45.5% 57.4% MEDP
Higher overall scoreMean of the five percentile scores vs peers 43/100 75/100 28/100 MEDP

Percentile Scorecard

DNAMEDPGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNAMEDPGH
Valuation 10 #10 of 11 50 #6 of 11 18 #76 of 92
Growth 50 #6 of 11 100 #1 of 11 49 #45 of 87
Profitability 10 #10 of 11 100 #1 of 11 7 #80 of 86
Financial Health 100 #1 of 13 50 #7 of 13 52 #47 of 97
Shareholder Returns – – 15 #48 of 56
Overall 43 75 28
  • DNA ranked among 13 companies in Pharma Services
  • MEDP ranked among 13 companies in Pharma Services
  • GH ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNAMEDPGHSPY
1 month +5.7%+8.9%+0.5% -0.2%
3 months +46.4%+18.0%+24.0% +3.9%
6 months +43.6%+64.5%+114.3% +8.2%
Year to date +35.6%+20.0%+74.3% +12.9%
1 year -15.8%+13.0%+151.3% +12.3%
3 years -79.1%+169.2%+613.4% +87.4%
3 years, per year -40.7%+39.1%+92.6% +23.3%
5 years -98.0%+206.7%+50.7% +67.9%
5 years, per year -54.4%+25.1%+8.5% +10.9%
10 years —+2,244.4%— +261.1%
10 years, per year —+37.1%— +13.7%

Risk

MeasureDNAMEDPGHSPY
Volatility, 1Y 101.5%45.5%57.4% 12.7%
Downside volatility, 1Y 103.1%54.0%48.7% 12.7%
Beta vs S&P 500, 1Y 3.030.671.03 1.00
Return / volatility, 1Y -0.160.282.64 0.97
Max drawdown, 5Y -99.1%-42.9%-86.7% -25.4%
From 52-week high -24.8%-0.4%-4.9% -1.2%
52-week high $14.98$676.77$187.22 $779.14
52-week low $5.48$393.42$69.58 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNAMEDPGH
P/E now vs peer median -2.4xmedian 32.1x 36.4xmedian 32.1x -52.2xmedian 24.6x
P/S now vs peer median 6.4xmedian 2.6x 6.6xmedian 2.6x 20.1xmedian 1.6x
EV/EBITDA now vs peer median -2.7xmedian 38.1x 28.6xmedian 38.1x -52.7xmedian 14.6x
P/FCF now vs peer median -4.1xmedian 21.5x 28.2xmedian 21.5x -98.8xmedian 21.6x
P/B now vs peer median 1.7xmedian 3.1x 32.2xmedian 3.1x -106.8xmedian 3.2x
PEG now vs peer median 0.02median 2.03 1.28median 2.03 -5.25median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNAMEDPGH
Revenue $111.86M $2.84B $1.18B
Gross profit $92.92M $827.16M $769.16M
Operating income -$290.69M $607.14M -$470.26M
Net income -$290.80M $517.83M -$453.44M
Free cash flow -$174.80M $667.63M -$240.72M
R&D $215.61M – $375.79M
EPS (diluted) $-5.24 $18.25 $-3.41
Cash & equivalents $84.54M $705.32M $1.05B
Shares (diluted) 55.46M 28.37M 132.87M
Enterprise value $70.60M $16.92B $20.37B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNAMEDPGH
P/E -2.4x 36.4x -52.2x
P/FCF -4.1x 28.2x -98.8x
P/Operating cash flow -4.2x 26.1x -128.5x
P/S 6.4x 6.6x 20.1x
P/B 1.7x 32.2x -106.8x
P/Tangible book 1.9x 34.1x -95.9x
EV/EBITDA -2.7x 28.6x -52.7x
EV/EBIT -2.2x 29.9x -48.4x
EV/Revenue 5.7x 6.4x 19.2x
EV/FCF -3.6x 27.2x -94.5x
EV/Operating cash flow -3.7x 25.1x -122.8x
PEG (3Y EPS CAGR) 0.02 1.28 -5.25

Growth

14 metrics
MetricDNAMEDPGH
Revenue growth (1Y) -46.8% 20.4% 42.7%
Revenue CAGR (3Y) -30.0% 16.8% 32.4%
Gross profit growth (1Y) -49.3% 12.8% 47.7%
Gross profit CAGR (3Y) -28.2% 18.0% –
Operating income growth (1Y) 2.4% 19.7% -2.1%
Operating income CAGR (3Y) 39.1% 23.0% 4.8%
Net income growth (1Y) 7.7% 19.6% -9.6%
Net income CAGR (3Y) 38.0% 23.8% 3.7%
EPS growth (1Y) 8.7% 21.5% -2.4%
EPS CAGR (3Y) -102.3% 28.5% 9.9%
Operating cash flow growth (1Y) 28.4% 1.7% 22.4%
Operating cash flow CAGR (3Y) 16.9% 20.5% 18.1%
Free cash flow growth (1Y) 36.2% -1.4% 11.4%
Free cash flow CAGR (3Y) 22.1% 20.9% 14.4%

Profitability

14 metrics
MetricDNAMEDPGH
Gross margin 83.1% 29.1% 65.0%
EBITDA margin -211.6% 22.4% -36.5%
Operating margin -259.9% 21.4% -39.7%
Pretax margin -264.1% 22.1% -38.4%
Net margin -260.0% 18.2% -38.3%
FCF margin -156.3% 23.5% -20.3%
Operating cash flow margin -152.2% 25.5% -15.7%
Return on equity -67.4% 101.7% –
Return on assets -28.7% 23.8% -23.7%
Return on invested capital – – –
Return on capital employed -31.0% 88.8% -29.9%
Asset turnover 0.1x 1.3x 0.6x
Cash conversion (OCF / net income) 0.6x 1.4x 0.4x
Stock comp / revenue 61.5% 0.8% 16.2%

Financial Health

11 metrics
MetricDNAMEDPGH
Debt / assets – – –
Debt / equity – – –
Net debt / EBITDA – – –
Debt / FCF – – –
Liabilities / assets 57.5% 74.6% 111.7%
Equity / assets 42.5% 25.4% -11.7%
Interest coverage – – -97.6x
Current ratio 4.6x 0.8x 4.0x
Quick ratio 1.4x 0.8x 3.5x
Cash ratio 1.2x 0.5x 3.1x
Altman Z-score -8.66 8.33 4.77

Shareholder Returns

7 metrics
MetricDNAMEDPGH
Dividend yield – – –
Net buyback yield – 1.3% -1.7%
Shareholder yield – 1.3% -1.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNAMEDPGH
Forward P/E – 37.9xFY2026 –
EPS, next fiscal year $-4.06FY2026 $17.80FY2026 $-3.33FY2026
EPS growth, next FY – +16.5%FY2026 –
EPS growth, the year after – +6.2% –
Revenue, next fiscal year $88.21MFY2026 $2.94BFY2026 $1.42BFY2026
Revenue growth, next FY -48.2%FY2026 +16.4%FY2026 +44.5%FY2026
Revenue growth, the year after +5.8% +6.0% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNAMEDPGH
Held by institutions 55.2% 87.8% 100.0%
Institutions holding 182 693 594
Change in shares held, QoQ +12.3% +3.2% -2.6%
Institutions buying 100 279 353
Institutions selling 39 302 180
Buyers to sellers 2.56 0.92 1.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNAMEDPGH
DNA 1.00 0.30 0.35
MEDP 0.30 1.00 0.27
GH 0.35 0.27 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, MEDP and GH?

Guardant Health (GH) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $832.69M, Medpace Holdings (MEDP) $19.28B, Guardant Health (GH) $24.31B.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Medpace Holdings (MEDP) +20.4%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Medpace Holdings (MEDP) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Medpace Holdings (MEDP) 18.2%, Guardant Health (GH) -38.3%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Ginkgo Bioworks Holdings (DNA) -15.8%, Medpace Holdings (MEDP) +13.0%, Guardant Health (GH) +151.3%. Over five years, Medpace Holdings (MEDP) compounded fastest (Ginkgo Bioworks Holdings (DNA) -54.4%/yr, Medpace Holdings (MEDP) +25.1%/yr, Guardant Health (GH) +8.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Medpace Holdings (MEDP) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 101.5%, Medpace Holdings (MEDP) 45.5%, Guardant Health (GH) 57.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, MEDP and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Medpace Holdings (MEDP) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.