DNA vs LDOS vs MEDP Stock Comparison

Ginkgo Bioworks Holdings, Leidos Holdings and Medpace Holdings Prices as of Oct 27, 2026 Peers: Industry group
LDOS Leidos Holdings, Inc.
$139.65 +12.9% 1M -26.2% 1Y
Market cap
$17.52B
P/E
12.7x
Revenue (TTM)
$17.63B
Div. yield
0.01%
Defense Industrials
3 wins
MEDP Medpace Holdings, Inc.
$673.79 +8.9% 1M +13.0% 1Y
Market cap
$19.28B
P/E
37.2x
Revenue (TTM)
$2.84B
Div. yield
–
Contract Research Healthcare
6 wins

Head to Head

9 decided of 12

Medpace Holdings leads on 6 of the 12 questions below (Medpace Holdings 6, Leidos Holdings 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNALDOSMEDPLeader
Larger companyMarket capitalisation $832.69M $17.52B $19.28B MEDP
Cheaper on earningsLower P/E, profitable companies only -2.9x 12.7x 37.2x LDOS
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 11.0x 37.9x LDOS
Faster revenue growthRevenue growth, trailing twelve months -46.8% +3.4% +20.4% MEDP
More profitableNet margin, trailing twelve months -260.0% 7.8% 18.2% MEDP
Better return on capitalReturn on invested capital — 13.9% — –
Less leveragedLower net debt / EBITDA — 2.3x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months -15.8% -26.2% +13.0% MEDP
Better 5-year returnAnnualised price return, 5 years -54.4%/yr +7.2%/yr +25.1%/yr MEDP
Less volatileAnnualised volatility, 1 year 101.5% 35.6% 45.5% LDOS
Higher overall scoreMean of the five percentile scores vs peers 43/100 70/100 75/100 MEDP

Percentile Scorecard

DNALDOSMEDP

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNALDOSMEDP
Valuation 10 #10 of 11 98 #3 of 100 50 #6 of 11
Growth 50 #6 of 11 58 #41 of 97 100 #1 of 11
Profitability 10 #10 of 11 86 #14 of 96 100 #1 of 11
Financial Health 100 #1 of 13 33 #71 of 105 50 #7 of 13
Shareholder Returns – 75 #17 of 65 –
Overall 43 70 75
  • DNA ranked among 13 companies in Pharma Services
  • LDOS ranked among 107 companies in Aerospace and Defense
  • MEDP ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNALDOSMEDPSPY
1 month +5.7%+12.9%+8.9% -0.2%
3 months +46.4%+18.0%+18.0% +3.9%
6 months +43.6%-4.4%+64.5% +8.2%
Year to date +35.6%-22.6%+20.0% +12.9%
1 year -15.8%-26.2%+13.0% +12.3%
3 years -79.1%+54.3%+169.2% +87.4%
3 years, per year -40.7%+15.6%+39.1% +23.3%
5 years -98.0%+41.7%+206.7% +67.9%
5 years, per year -54.4%+7.2%+25.1% +10.9%
10 years —+239.1%+2,244.4% +261.1%
10 years, per year —+13.0%+37.1% +13.7%

Risk

MeasureDNALDOSMEDPSPY
Volatility, 1Y 101.5%35.6%45.5% 12.7%
Downside volatility, 1Y 103.1%37.2%54.0% 12.7%
Beta vs S&P 500, 1Y 3.030.260.67 1.00
Return / volatility, 1Y -0.16-0.740.28 0.97
Max drawdown, 5Y -99.1%-50.3%-42.9% -25.4%
From 52-week high -24.8%-30.0%-0.4% -1.2%
52-week high $14.98$199.55$676.77 $779.14
52-week low $5.48$100.00$393.42 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNALDOSMEDP
P/E now vs peer median -2.4xmedian 32.1x 12.8xmedian 26.5x 36.4xmedian 32.1x
P/S now vs peer median 6.4xmedian 2.6x 1.0xmedian 3.0x 6.6xmedian 2.6x
EV/EBITDA now vs peer median -2.7xmedian 38.1x 9.8xmedian 14.6x 28.6xmedian 38.1x
P/FCF now vs peer median -4.1xmedian 21.5x 8.1xmedian 26.4x 28.2xmedian 21.5x
P/B now vs peer median 1.7xmedian 3.1x 3.3xmedian 2.5x 32.2xmedian 3.1x
PEG now vs peer median 0.02median 2.03 0.45median 0.90 1.28median 2.03

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNALDOSMEDP
Revenue $111.86M $17.63B $2.84B
Gross profit $92.92M $3.14B $827.16M
Operating income -$290.69M $2.03B $607.14M
Net income -$290.80M $1.40B $517.83M
Free cash flow -$174.80M $2.16B $667.63M
R&D $215.61M – –
EPS (diluted) $-5.24 $10.92 $18.25
Cash & equivalents $84.54M $748.00M $705.32M
Total debt – $21.66B –
Shares (diluted) 55.46M 126.00M 28.37M
Enterprise value $70.60M $14.24B $16.92B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNALDOSMEDP
P/E -2.4x 12.8x 36.4x
P/FCF -4.1x 8.1x 28.2x
P/Operating cash flow -4.2x 7.6x 26.1x
P/S 6.4x 1.0x 6.6x
P/B 1.7x 3.3x 32.2x
P/Tangible book 1.9x 4.0x 34.1x
EV/EBITDA -2.7x 9.8x 28.6x
EV/EBIT -2.2x 11.2x 29.9x
EV/Revenue 5.7x 1.3x 6.4x
EV/FCF -3.6x 10.5x 27.2x
EV/Operating cash flow -3.7x 9.9x 25.1x
PEG (3Y EPS CAGR) 0.02 0.45 1.28

Growth

14 metrics
MetricDNALDOSMEDP
Revenue growth (1Y) -46.8% 3.4% 20.4%
Revenue CAGR (3Y) -30.0% 5.9% 16.8%
Gross profit growth (1Y) -49.3% 4.8% 12.8%
Gross profit CAGR (3Y) -28.2% 14.4% 18.0%
Operating income growth (1Y) 2.4% -0.4% 19.7%
Operating income CAGR (3Y) 39.1% 21.1% 23.0%
Net income growth (1Y) 7.7% -0.8% 19.6%
Net income CAGR (3Y) 38.0% 24.8% 23.8%
EPS growth (1Y) 8.7% 1.3% 21.5%
EPS CAGR (3Y) -102.3% 28.6% 28.5%
Operating cash flow growth (1Y) 28.4% 54.9% 1.7%
Operating cash flow CAGR (3Y) 16.9% 35.7% 20.5%
Free cash flow growth (1Y) 36.2% 63.2% -1.4%
Free cash flow CAGR (3Y) 22.1% 41.7% 20.9%

Profitability

14 metrics
MetricDNALDOSMEDP
Gross margin 83.1% 17.8% 29.1%
EBITDA margin -211.6% 13.2% 22.4%
Operating margin -259.9% 11.5% 21.4%
Pretax margin -264.1% 10.2% 22.1%
Net margin -260.0% 7.8% 18.2%
FCF margin -156.3% 12.3% 23.5%
Operating cash flow margin -152.2% 13.0% 25.5%
Return on equity -67.4% 26.8% 101.7%
Return on assets -28.7% 9.0% 23.8%
Return on invested capital – 13.9% –
Return on capital employed -31.0% 16.5% 88.8%
Asset turnover 0.1x 1.1x 1.3x
Cash conversion (OCF / net income) 0.6x 1.6x 1.4x
Stock comp / revenue 61.5% 0.6% 0.8%

Financial Health

11 metrics
MetricDNALDOSMEDP
Debt / assets – 38.6% –
Debt / equity – 1.1x –
Net debt / EBITDA – 2.3x –
Debt / FCF – 2.8x –
Liabilities / assets 57.5% 65.9% 74.6%
Equity / assets 42.5% 34.1% 25.4%
Interest coverage – – –
Current ratio 4.6x 1.6x 0.8x
Quick ratio 1.4x 1.4x 0.8x
Cash ratio 1.2x 0.2x 0.5x
Altman Z-score -8.66 3.20 8.33

Shareholder Returns

7 metrics
MetricDNALDOSMEDP
Dividend yield – 1.2% –
Net buyback yield – 3.8% 1.3%
Shareholder yield – 5.0% 1.3%
Payout ratio (earnings) – 15.5% –
Payout ratio (FCF) – 10.0% –
Dividend growth (1Y) – 3.3% –
Dividend CAGR (3Y) – 2.8% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNALDOSMEDP
Forward P/E – 11.0xFY2026 37.9xFY2026
EPS, next fiscal year $-4.06FY2026 $12.75FY2026 $17.80FY2026
EPS growth, next FY – +6.3%FY2026 +16.5%FY2026
EPS growth, the year after – -9.0% +6.2%
Revenue, next fiscal year $88.21MFY2026 $17.52BFY2026 $2.94BFY2026
Revenue growth, next FY -48.2%FY2026 +2.0%FY2026 +16.4%FY2026
Revenue growth, the year after +5.8% +14.9% +6.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNALDOSMEDP
Held by institutions 55.2% 79.3% 87.8%
Institutions holding 182 773 693
Change in shares held, QoQ +12.3% +4.1% +3.2%
Institutions buying 100 380 279
Institutions selling 39 294 302
Buyers to sellers 2.56 1.29 0.92

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNALDOSMEDP
DNA 1.00 0.09 0.30
LDOS 0.09 1.00 0.14
MEDP 0.30 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, LDOS and MEDP?

Medpace Holdings (MEDP) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $832.69M, Leidos Holdings (LDOS) $17.52B, Medpace Holdings (MEDP) $19.28B.

Which stock is cheaper, DNA, LDOS and MEDP?

Leidos Holdings (LDOS) trades on the lowest price-to-earnings ratio (Ginkgo Bioworks Holdings (DNA) -2.9x, Leidos Holdings (LDOS) 12.7x, Medpace Holdings (MEDP) 37.2x). On next year's consensus earnings, Leidos Holdings (LDOS) is cheapest (Leidos Holdings (LDOS) 11.0x, Medpace Holdings (MEDP) 37.9x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Medpace Holdings (MEDP) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Leidos Holdings (LDOS) +3.4%, Medpace Holdings (MEDP) +20.4%.

Which company is more profitable?

Medpace Holdings (MEDP) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Leidos Holdings (LDOS) 7.8%, Medpace Holdings (MEDP) 18.2%).

Which stock has performed better?

Over the past year Medpace Holdings (MEDP) returned the most: Ginkgo Bioworks Holdings (DNA) -15.8%, Leidos Holdings (LDOS) -26.2%, Medpace Holdings (MEDP) +13.0%. Over five years, Medpace Holdings (MEDP) compounded fastest (Ginkgo Bioworks Holdings (DNA) -54.4%/yr, Leidos Holdings (LDOS) +7.2%/yr, Medpace Holdings (MEDP) +25.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Ginkgo Bioworks Holdings (DNA) 0.00%, Leidos Holdings (LDOS) 0.01%, Medpace Holdings (MEDP) 0.00%. Ginkgo Bioworks Holdings (DNA) and Medpace Holdings (MEDP) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Leidos Holdings (LDOS) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 101.5%, Leidos Holdings (LDOS) 35.6%, Medpace Holdings (MEDP) 45.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, LDOS and MEDP?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Medpace Holdings (MEDP) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.