DNA vs LDOS vs GH Stock Comparison

Ginkgo Bioworks Holdings, Leidos Holdings and Guardant Health Prices as of Oct 26, 2026 Peers: Industry group
LDOS Leidos Holdings, Inc.
$139.91 +13.2% 1M -26.3% 1Y
Market cap
$17.52B
P/E
12.7x
Revenue (TTM)
$17.63B
Div. yield
0.01%
Defense Industrials
3 wins
GH Guardant Health, Inc.
$173.25 -2.3% 1M +140.1% 1Y
Market cap
$23.45B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
4 wins

Head to Head

7 decided of 12

Guardant Health leads on 4 of the 12 questions below (Guardant Health 4, Leidos Holdings 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNALDOSGHLeader
Larger companyMarket capitalisation $683.04M $17.52B $23.45B GH
Cheaper on earningsLower P/E, profitable companies only -2.3x 12.7x -51.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 11.0x — –
Faster revenue growthRevenue growth, trailing twelve months -46.8% +3.4% +42.7% GH
More profitableNet margin, trailing twelve months -260.0% 7.8% -38.3% LDOS
Better return on capitalReturn on invested capital — 13.9% — –
Less leveragedLower net debt / EBITDA — 2.3x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.01% 0.00% –
Better 1-year returnPrice return, last 12 months -26.3% -26.3% +140.1% GH
Better 5-year returnAnnualised price return, 5 years -55.5%/yr +7.2%/yr +9.1%/yr GH
Less volatileAnnualised volatility, 1 year 100.9% 35.6% 57.4% LDOS
Higher overall scoreMean of the five percentile scores vs peers 45/100 70/100 28/100 LDOS

Percentile Scorecard

DNALDOSGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNALDOSGH
Valuation 10 #10 of 11 98 #3 of 100 17 #77 of 93
Growth 60 #5 of 11 57 #42 of 97 48 #46 of 88
Profitability 10 #10 of 11 85 #15 of 96 7 #81 of 87
Financial Health 100 #1 of 13 34 #70 of 105 51 #50 of 100
Shareholder Returns – 75 #17 of 64 15 #48 of 56
Overall 45 70 28
  • DNA ranked among 13 companies in Pharma Services
  • LDOS ranked among 107 companies in Aerospace and Defense
  • GH ranked among 103 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNALDOSGHSPY
1 month -6.2%+13.2%-2.3% -0.8%
3 months +34.2%+21.6%+19.1% +3.5%
6 months +27.9%-3.0%+95.8% +7.0%
Year to date +20.3%-22.4%+69.6% +12.2%
1 year -26.3%-26.3%+140.1% +13.0%
3 years -81.5%+54.6%+594.1% +86.3%
3 years, per year -43.0%+15.6%+90.8% +23.1%
5 years -98.3%+41.4%+54.3% +68.6%
5 years, per year -55.5%+7.2%+9.1% +11.0%
10 years —+235.6%— +258.0%
10 years, per year —+12.9%— +13.6%

Risk

MeasureDNALDOSGHSPY
Volatility, 1Y 100.9%35.6%57.4% 12.7%
Downside volatility, 1Y 103.1%37.3%48.7% 12.7%
Beta vs S&P 500, 1Y 2.990.261.02 1.00
Return / volatility, 1Y -0.26-0.742.44 1.02
Max drawdown, 5Y -99.1%-50.3%-86.7% -25.4%
From 52-week high -33.2%-29.9%-7.5% -1.8%
52-week high $14.98$199.55$187.22 $779.14
52-week low $5.48$100.00$69.58 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNALDOSGH
P/E now vs peer median -2.1xmedian 36.5x 12.8xmedian 26.8x -50.8xmedian 25.1x
P/S now vs peer median 5.7xmedian 2.7x 1.0xmedian 2.9x 19.6xmedian 1.6x
EV/EBITDA now vs peer median -2.3xmedian 37.7x 9.8xmedian 15.2x -51.2xmedian 14.5x
P/FCF now vs peer median -3.6xmedian 20.7x 8.1xmedian 25.5x -96.2xmedian 22.4x
P/B now vs peer median 1.5xmedian 2.9x 3.3xmedian 2.5x -103.9xmedian 3.1x
PEG now vs peer median 0.02median 2.04 0.45median 0.94 -5.11median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNALDOSGH
Revenue $111.86M $17.63B $1.18B
Gross profit $92.92M $3.14B $769.16M
Operating income -$290.69M $2.03B -$470.26M
Net income -$290.80M $1.40B -$453.44M
Free cash flow -$174.80M $2.16B -$240.72M
R&D $215.61M – $375.79M
EPS (diluted) $-5.24 $10.92 $-3.41
Cash & equivalents $84.54M $748.00M $1.05B
Total debt – $21.66B –
Shares (diluted) 55.46M 126.00M 132.87M
Enterprise value -$79.05M $14.23B $19.51B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNALDOSGH
P/E -2.1x 12.8x -50.8x
P/FCF -3.6x 8.1x -96.2x
P/Operating cash flow -3.7x 7.6x -125.0x
P/S 5.7x 1.0x 19.6x
P/B 1.5x 3.3x -103.9x
P/Tangible book 1.7x 4.0x -93.3x
EV/EBITDA -2.3x 9.8x -51.2x
EV/EBIT -1.9x 11.3x -47.0x
EV/Revenue 4.9x 1.3x 18.7x
EV/FCF -3.2x 10.6x -91.8x
EV/Operating cash flow -3.2x 9.9x -119.3x
PEG (3Y EPS CAGR) 0.02 0.45 -5.11

Growth

14 metrics
MetricDNALDOSGH
Revenue growth (1Y) -46.8% 3.4% 42.7%
Revenue CAGR (3Y) -30.0% 5.9% 32.4%
Gross profit growth (1Y) -49.3% 4.8% 47.7%
Gross profit CAGR (3Y) -28.2% 14.4% –
Operating income growth (1Y) 2.4% -0.4% -2.1%
Operating income CAGR (3Y) 39.1% 21.1% 4.8%
Net income growth (1Y) 7.7% -0.8% -9.6%
Net income CAGR (3Y) 38.0% 24.8% 3.7%
EPS growth (1Y) 8.7% 1.3% -2.4%
EPS CAGR (3Y) -102.3% 28.6% 9.9%
Operating cash flow growth (1Y) 28.4% 54.9% 22.4%
Operating cash flow CAGR (3Y) 16.9% 35.7% 18.1%
Free cash flow growth (1Y) 36.2% 63.2% 11.4%
Free cash flow CAGR (3Y) 22.1% 41.7% 14.4%

Profitability

14 metrics
MetricDNALDOSGH
Gross margin 83.1% 17.8% 65.0%
EBITDA margin -211.6% 13.2% -36.5%
Operating margin -259.9% 11.5% -39.7%
Pretax margin -264.1% 10.2% -38.4%
Net margin -260.0% 7.8% -38.3%
FCF margin -156.3% 12.3% -20.3%
Operating cash flow margin -152.2% 13.0% -15.7%
Return on equity -67.4% 26.8% –
Return on assets -28.7% 9.0% -23.7%
Return on invested capital – 13.9% –
Return on capital employed -31.0% 16.5% -29.9%
Asset turnover 0.1x 1.1x 0.6x
Cash conversion (OCF / net income) 0.6x 1.6x 0.4x
Stock comp / revenue 61.5% 0.6% 16.2%

Financial Health

11 metrics
MetricDNALDOSGH
Debt / assets – 38.6% –
Debt / equity – 1.1x –
Net debt / EBITDA – 2.3x –
Debt / FCF – 2.8x –
Liabilities / assets 57.5% 65.9% 111.7%
Equity / assets 42.5% 34.1% -11.7%
Interest coverage – – -97.6x
Current ratio 4.6x 1.6x 4.0x
Quick ratio 1.4x 1.4x 3.5x
Cash ratio 1.2x 0.2x 3.1x
Altman Z-score -8.75 3.20 4.59

Shareholder Returns

7 metrics
MetricDNALDOSGH
Dividend yield – 1.2% –
Net buyback yield – 3.7% -1.7%
Shareholder yield – 5.0% -1.7%
Payout ratio (earnings) – 15.5% –
Payout ratio (FCF) – 10.0% –
Dividend growth (1Y) – 3.3% –
Dividend CAGR (3Y) – 2.8% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNALDOSGH
Forward P/E – 11.0xFY2026 –
EPS, next fiscal year $-4.06FY2026 $12.75FY2026 $-3.33FY2026
EPS growth, next FY – +6.3%FY2026 –
EPS growth, the year after – -9.0% –
Revenue, next fiscal year $88.21MFY2026 $17.52BFY2026 $1.42BFY2026
Revenue growth, next FY -48.2%FY2026 +2.0%FY2026 +44.5%FY2026
Revenue growth, the year after +5.8% +14.9% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNALDOSGH
Held by institutions 55.2% 79.3% 100.0%
Institutions holding 182 773 594
Change in shares held, QoQ +12.3% +4.1% -2.6%
Institutions buying 100 380 353
Institutions selling 39 294 180
Buyers to sellers 2.56 1.29 1.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNALDOSGH
DNA 1.00 0.09 0.34
LDOS 0.09 1.00 0.09
GH 0.34 0.09 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, LDOS and GH?

Guardant Health (GH) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $683.04M, Leidos Holdings (LDOS) $17.52B, Guardant Health (GH) $23.45B.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Leidos Holdings (LDOS) +3.4%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Leidos Holdings (LDOS) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Leidos Holdings (LDOS) 7.8%, Guardant Health (GH) -38.3%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Ginkgo Bioworks Holdings (DNA) -26.3%, Leidos Holdings (LDOS) -26.3%, Guardant Health (GH) +140.1%. Over five years, Guardant Health (GH) compounded fastest (Ginkgo Bioworks Holdings (DNA) -55.5%/yr, Leidos Holdings (LDOS) +7.2%/yr, Guardant Health (GH) +9.1%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Ginkgo Bioworks Holdings (DNA) 0.00%, Leidos Holdings (LDOS) 0.01%, Guardant Health (GH) 0.00%. Ginkgo Bioworks Holdings (DNA) and Guardant Health (GH) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Leidos Holdings (LDOS) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 100.9%, Leidos Holdings (LDOS) 35.6%, Guardant Health (GH) 57.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, LDOS and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.