DNA vs LDOS vs CRL Stock Comparison

Ginkgo Bioworks Holdings, Leidos Holdings and Charles River Laboratories International Prices as of Oct 28, 2026 Peers: Industry group
LDOS Leidos Holdings, Inc.
$139.62 +14.1% 1M -25.7% 1Y
Market cap
$17.52B
P/E
12.8x
Revenue (TTM)
$17.63B
Div. yield
1.23%
Defense Industrials
8 wins

Head to Head

10 decided of 12

Leidos Holdings leads on 8 of the 12 questions below (Leidos Holdings 8, Charles River Laboratories International 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNALDOSCRLLeader
Larger companyMarket capitalisation $850.54M $17.52B $17.86B CRL
Cheaper on earningsLower P/E, profitable companies only -2.9x 12.8x -75.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 11.0x 34.3x LDOS
Faster revenue growthRevenue growth, trailing twelve months -46.8% +3.4% -0.7% LDOS
More profitableNet margin, trailing twelve months -260.0% 7.8% -6.0% LDOS
Better return on capitalReturn on invested capital — 13.9% 1.6% LDOS
Less leveragedLower net debt / EBITDA — 2.3x 6.3x LDOS
Higher dividend yieldTrailing dividend yield — 1.23% — –
Better 1-year returnPrice return, last 12 months +4.8% -25.7% +99.1% CRL
Better 5-year returnAnnualised price return, 5 years -52.5%/yr +6.9%/yr -3.6%/yr LDOS
Less volatileAnnualised volatility, 1 year 102.8% 35.6% 45.9% LDOS
Higher overall scoreMean of the five percentile scores vs peers 43/100 70/100 43/100 LDOS

Percentile Scorecard

DNALDOSCRL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNALDOSCRL
Valuation 10 #10 of 11 98 #3 of 100 50 #6 of 11
Growth 50 #6 of 11 58 #41 of 97 10 #10 of 11
Profitability 10 #10 of 11 86 #14 of 96 70 #4 of 11
Financial Health 100 #1 of 13 32 #72 of 105 42 #8 of 13
Shareholder Returns – 73 #18 of 65 –
Overall 43 70 43
  • DNA ranked among 13 companies in Pharma Services
  • LDOS ranked among 107 companies in Aerospace and Defense
  • CRL ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNALDOSCRLSPY
1 month +27.8%+14.1%+27.0% +0.9%
3 months +75.4%+22.1%+59.4% +5.9%
6 months +78.0%-4.3%+128.4% +8.5%
Year to date +60.6%-22.6%+87.6% +13.3%
1 year +4.8%-25.7%+99.1% +12.4%
3 years -75.3%+54.3%+116.8% +88.1%
3 years, per year -37.3%+15.6%+29.4% +23.5%
5 years -97.6%+39.6%-16.6% +68.2%
5 years, per year -52.5%+6.9%-3.6% +11.0%
10 years —+237.2%+392.3% +263.4%
10 years, per year —+12.9%+17.3% +13.8%

Risk

MeasureDNALDOSCRLSPY
Volatility, 1Y 102.8%35.6%45.9% 12.7%
Downside volatility, 1Y 103.3%37.1%42.8% 12.7%
Beta vs S&P 500, 1Y 3.060.261.28 1.00
Return / volatility, 1Y 0.05-0.722.16 0.98
Max drawdown, 5Y -99.1%-50.3%-77.8% -25.4%
From 52-week high -10.9%-30.0%0.0% -0.9%
52-week high $14.98$199.55$374.16 $779.14
52-week low $5.48$100.00$149.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNALDOSCRL
P/E now vs peer median -2.9xmedian 37.4x 12.8xmedian 26.4x -75.3xmedian 37.4x
P/S now vs peer median 7.6xmedian 2.7x 1.0xmedian 3.0x 4.5xmedian 2.7x
EV/EBITDA now vs peer median -3.2xmedian 39.5x 9.8xmedian 14.5x 52.3xmedian 39.5x
P/FCF now vs peer median -4.9xmedian 22.1x 8.1xmedian 26.1x 48.2xmedian 22.1x
P/B now vs peer median 2.0xmedian 3.4x 3.3xmedian 2.5x 6.3xmedian 3.4x
PEG now vs peer median 0.03median 2.08 0.45median 0.90 2.08median 2.08

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNALDOSCRL
Revenue $111.86M $17.63B $4.00B
Gross profit $92.92M $3.14B $1.31B
Operating income -$290.69M $2.03B $90.14M
Net income -$290.80M $1.40B -$239.23M
Free cash flow -$174.80M $2.16B $370.61M
R&D $215.61M – –
EPS (diluted) $-5.24 $10.92 $-4.97
Cash & equivalents $84.54M $748.00M $192.03M
Total debt – $21.66B $2.62B
Shares (diluted) 55.46M 126.00M 48.02M
Enterprise value $88.46M $14.29B $17.10B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNALDOSCRL
P/E -2.9x 12.8x -75.3x
P/FCF -4.9x 8.1x 48.2x
P/Operating cash flow -5.0x 7.6x 30.7x
P/S 7.6x 1.0x 4.5x
P/B 2.0x 3.3x 6.3x
P/Tangible book 2.3x 4.0x 6.9x
EV/EBITDA -3.2x 9.8x 52.3x
EV/EBIT -2.6x 11.2x 225.0x
EV/Revenue 6.8x 1.3x 5.1x
EV/FCF -4.4x 10.5x 54.7x
EV/Operating cash flow -4.5x 9.9x 34.8x
PEG (3Y EPS CAGR) 0.03 0.45 2.08

Growth

14 metrics
MetricDNALDOSCRL
Revenue growth (1Y) -46.8% 3.4% -0.7%
Revenue CAGR (3Y) -30.0% 5.9% -1.5%
Gross profit growth (1Y) -49.3% 4.8% -0.1%
Gross profit CAGR (3Y) -28.2% 14.4% -5.5%
Operating income growth (1Y) 2.4% -0.4% -27.6%
Operating income CAGR (3Y) 39.1% 21.1% -48.2%
Net income growth (1Y) 7.7% -0.8% -268.7%
Net income CAGR (3Y) 38.0% 24.8% -35.5%
EPS growth (1Y) 8.7% 1.3% -253.8%
EPS CAGR (3Y) -102.3% 28.6% -36.2%
Operating cash flow growth (1Y) 28.4% 54.9% -26.1%
Operating cash flow CAGR (3Y) 16.9% 35.7% -2.3%
Free cash flow growth (1Y) 36.2% 63.2% -35.9%
Free cash flow CAGR (3Y) 22.1% 41.7% 8.6%

Profitability

14 metrics
MetricDNALDOSCRL
Gross margin 83.1% 17.8% 32.7%
EBITDA margin -211.6% 13.2% 9.7%
Operating margin -259.9% 11.5% 2.3%
Pretax margin -264.1% 10.2% -4.6%
Net margin -260.0% 7.8% -6.0%
FCF margin -156.3% 12.3% 9.3%
Operating cash flow margin -152.2% 13.0% 14.6%
Return on equity -67.4% 26.8% -8.2%
Return on assets -28.7% 9.0% -3.1%
Return on invested capital – 13.9% 1.6%
Return on capital employed -31.0% 16.5% 1.4%
Asset turnover 0.1x 1.1x 0.5x
Cash conversion (OCF / net income) 0.6x 1.6x -2.4x
Stock comp / revenue 61.5% 0.6% 2.1%

Financial Health

11 metrics
MetricDNALDOSCRL
Debt / assets – 38.6% 34.8%
Debt / equity – 1.1x 0.9x
Net debt / EBITDA – 2.3x 6.3x
Debt / FCF – 2.8x 7.1x
Liabilities / assets 57.5% 65.9% 62.2%
Equity / assets 42.5% 34.1% 37.8%
Interest coverage – – 0.8x
Current ratio 4.6x 1.6x 1.3x
Quick ratio 1.4x 1.4x 0.8x
Cash ratio 1.2x 0.2x 0.2x
Altman Z-score -8.53 3.20 3.17

Shareholder Returns

7 metrics
MetricDNALDOSCRL
Dividend yield – 1.2% –
Net buyback yield – 3.8% 1.8%
Shareholder yield – 5.0% 1.8%
Payout ratio (earnings) – 15.5% –
Payout ratio (FCF) – 10.0% –
Dividend growth (1Y) – 3.3% –
Dividend CAGR (3Y) – 2.8% –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNALDOSCRL
Forward P/E – 11.0xFY2026 34.3xFY2026
EPS, next fiscal year $-4.06FY2026 $12.75FY2026 $10.90FY2026
EPS growth, next FY – +6.3%FY2026 +6.0%FY2026
EPS growth, the year after – -9.0% +20.5%
Revenue, next fiscal year $88.21MFY2026 $17.52BFY2026 $3.82BFY2026
Revenue growth, next FY -48.2%FY2026 +2.0%FY2026 -4.9%FY2026
Revenue growth, the year after +5.8% +14.9% +0.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNALDOSCRL
Held by institutions 55.2% 79.3% 100.0%
Institutions holding 182 773 570
Change in shares held, QoQ +12.3% +4.1% -0.7%
Institutions buying 100 380 270
Institutions selling 39 294 204
Buyers to sellers 2.56 1.29 1.32

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNALDOSCRL
DNA 1.00 0.09 0.35
LDOS 0.09 1.00 0.19
CRL 0.35 0.19 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, LDOS and CRL?

Charles River Laboratories International (CRL) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $850.54M, Leidos Holdings (LDOS) $17.52B, Charles River Laboratories International (CRL) $17.86B.

Which company is growing faster?

Leidos Holdings (LDOS) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Leidos Holdings (LDOS) +3.4%, Charles River Laboratories International (CRL) -0.7%.

Which company is more profitable?

Leidos Holdings (LDOS) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Leidos Holdings (LDOS) 7.8%, Charles River Laboratories International (CRL) -6.0%). On return on invested capital, Leidos Holdings (LDOS) leads (Leidos Holdings (LDOS) 13.9%, Charles River Laboratories International (CRL) 1.6%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Ginkgo Bioworks Holdings (DNA) +4.8%, Leidos Holdings (LDOS) -25.7%, Charles River Laboratories International (CRL) +99.1%. Over five years, Leidos Holdings (LDOS) compounded fastest (Ginkgo Bioworks Holdings (DNA) -52.5%/yr, Leidos Holdings (LDOS) +6.9%/yr, Charles River Laboratories International (CRL) -3.6%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Leidos Holdings (LDOS) 1.23%. Ginkgo Bioworks Holdings (DNA) and Charles River Laboratories International (CRL) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Leidos Holdings (LDOS) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 102.8%, Leidos Holdings (LDOS) 35.6%, Charles River Laboratories International (CRL) 45.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, LDOS and CRL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Leidos Holdings (LDOS) leads on 8. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.