DNA vs IQV vs CRL Stock Comparison

Ginkgo Bioworks Holdings, Iqvia Holdings and Charles River Laboratories International Prices as of Oct 28, 2026 Peers: Industry group
IQV Iqvia Holdings Inc.
$279.01 +3.1% 1M +27.9% 1Y
Market cap
$45.19B
P/E
32.4x
Revenue (TTM)
$17.31B
Div. yield
–
Contract Research Healthcare
9 wins

Head to Head

10 decided of 12

Iqvia Holdings leads on 9 of the 12 questions below (Iqvia Holdings 9, Charles River Laboratories International 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNAIQVCRLLeader
Larger companyMarket capitalisation $795.12M $45.19B $18.05B IQV
Cheaper on earningsLower P/E, profitable companies only -2.7x 32.4x -75.7x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 23.0x 34.3x IQV
Faster revenue growthRevenue growth, trailing twelve months -46.8% +8.8% -0.7% IQV
More profitableNet margin, trailing twelve months -260.0% 8.1% -6.0% IQV
Better return on capitalReturn on invested capital — 8.2% 1.6% IQV
Less leveragedLower net debt / EBITDA — 3.9x 6.3x IQV
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +4.8% +27.9% +99.1% CRL
Better 5-year returnAnnualised price return, 5 years -52.5%/yr +1.3%/yr -3.6%/yr IQV
Less volatileAnnualised volatility, 1 year 102.8% 40.4% 45.9% IQV
Higher overall scoreMean of the five percentile scores vs peers 43/100 71/100 43/100 IQV

Percentile Scorecard

DNAIQVCRL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNAIQVCRL
Valuation 10 #10 of 11 80 #3 of 11 50 #6 of 11
Growth 50 #6 of 11 80 #3 of 11 10 #10 of 11
Profitability 10 #10 of 11 90 #2 of 11 70 #4 of 11
Financial Health 100 #1 of 13 33 #9 of 13 42 #8 of 13
Shareholder Returns – – –
Overall 43 71 43
  • DNA ranked among 13 companies in Pharma Services
  • IQV ranked among 13 companies in Pharma Services
  • CRL ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNAIQVCRLSPY
1 month +27.8%+3.1%+27.0% +0.9%
3 months +75.4%+12.6%+59.4% +5.9%
6 months +78.0%+78.1%+128.4% +8.5%
Year to date +60.6%+23.8%+87.6% +13.3%
1 year +4.8%+27.9%+99.1% +12.4%
3 years -75.3%+55.1%+116.8% +88.1%
3 years, per year -37.3%+15.8%+29.4% +23.5%
5 years -97.6%+6.7%-16.6% +68.2%
5 years, per year -52.5%+1.3%-3.6% +11.0%
10 years —+288.8%+392.3% +263.4%
10 years, per year —+14.5%+17.3% +13.8%

Risk

MeasureDNAIQVCRLSPY
Volatility, 1Y 102.8%40.4%45.9% 12.7%
Downside volatility, 1Y 103.3%39.2%42.8% 12.7%
Beta vs S&P 500, 1Y 3.060.741.28 1.00
Return / volatility, 1Y 0.050.692.16 0.98
Max drawdown, 5Y -99.1%-51.5%-77.8% -25.4%
From 52-week high -10.9%-0.1%0.0% -0.9%
52-week high $14.98$279.38$374.16 $779.14
52-week low $5.48$156.66$149.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNAIQVCRL
P/E now vs peer median -2.9xmedian 37.4x 33.0xmedian 37.4x -75.3xmedian 37.4x
P/S now vs peer median 7.6xmedian 2.7x 2.7xmedian 2.7x 4.5xmedian 2.7x
EV/EBITDA now vs peer median -3.2xmedian 39.5x 17.2xmedian 39.5x 52.3xmedian 39.5x
P/FCF now vs peer median -4.9xmedian 22.1x 22.1xmedian 22.1x 48.2xmedian 22.1x
P/B now vs peer median 2.0xmedian 3.4x 6.8xmedian 3.4x 6.3xmedian 3.4x
PEG now vs peer median 0.03median 2.08 2.86median 2.08 2.08median 2.08

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNAIQVCRL
Revenue $111.86M $17.31B $4.00B
Gross profit $92.92M $5.72B $1.31B
Operating income -$290.69M $2.22B $90.14M
Net income -$290.80M $1.40B -$239.23M
Free cash flow -$174.80M $2.08B $370.61M
R&D $215.61M – –
EPS (diluted) $-5.24 $8.35 $-4.97
Cash & equivalents $84.54M $2.25B $192.03M
Total debt – $16.07B $2.62B
Shares (diluted) 55.46M 167.00M 48.02M
Enterprise value $33.03M $36.45B $17.24B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNAIQVCRL
P/E -2.9x 33.0x -75.3x
P/FCF -4.9x 22.1x 48.2x
P/Operating cash flow -5.0x 16.8x 30.7x
P/S 7.6x 2.7x 4.5x
P/B 2.0x 6.8x 6.3x
P/Tangible book 2.3x 22.4x 6.9x
EV/EBITDA -3.2x 17.2x 52.3x
EV/EBIT -2.6x 26.9x 225.0x
EV/Revenue 6.8x 3.4x 5.1x
EV/FCF -4.4x 28.7x 54.7x
EV/Operating cash flow -4.5x 21.8x 34.8x
PEG (3Y EPS CAGR) 0.03 2.86 2.08

Growth

14 metrics
MetricDNAIQVCRL
Revenue growth (1Y) -46.8% 8.8% -0.7%
Revenue CAGR (3Y) -30.0% 5.2% -1.5%
Gross profit growth (1Y) -49.3% 6.6% -0.1%
Gross profit CAGR (3Y) -28.2% 3.4% -5.5%
Operating income growth (1Y) 2.4% 1.7% -27.6%
Operating income CAGR (3Y) 39.1% 6.2% -48.2%
Net income growth (1Y) 7.7% 9.0% -268.7%
Net income CAGR (3Y) 38.0% 7.8% -35.5%
EPS growth (1Y) 8.7% 11.7% -253.8%
EPS CAGR (3Y) -102.3% 11.5% -36.2%
Operating cash flow growth (1Y) 28.4% -2.4% -26.1%
Operating cash flow CAGR (3Y) 16.9% 11.7% -2.3%
Free cash flow growth (1Y) 36.2% -6.0% -35.9%
Free cash flow CAGR (3Y) 22.1% 16.3% 8.6%

Profitability

14 metrics
MetricDNAIQVCRL
Gross margin 83.1% 33.1% 32.7%
EBITDA margin -211.6% 20.0% 9.7%
Operating margin -259.9% 12.8% 2.3%
Pretax margin -264.1% 9.0% -4.6%
Net margin -260.0% 8.1% -6.0%
FCF margin -156.3% 12.0% 9.3%
Operating cash flow margin -152.2% 15.8% 14.6%
Return on equity -67.4% 21.4% -8.2%
Return on assets -28.7% 4.6% -3.1%
Return on invested capital – 8.2% 1.6%
Return on capital employed -31.0% 9.9% 1.4%
Asset turnover 0.1x 0.6x 0.5x
Cash conversion (OCF / net income) 0.6x 2.0x -2.4x
Stock comp / revenue 61.5% 1.8% 2.1%

Financial Health

11 metrics
MetricDNAIQVCRL
Debt / assets – 52.7% 34.8%
Debt / equity – 2.4x 0.9x
Net debt / EBITDA – 3.9x 6.3x
Debt / FCF – 7.7x 7.1x
Liabilities / assets 57.5% 77.7% 62.2%
Equity / assets 42.5% 22.3% 37.8%
Interest coverage – 2.8x 0.8x
Current ratio 4.6x 0.8x 1.3x
Quick ratio 1.4x 1.0x 0.8x
Cash ratio 1.2x 0.3x 0.2x
Altman Z-score -8.53 2.30 3.17

Shareholder Returns

7 metrics
MetricDNAIQVCRL
Dividend yield – – –
Net buyback yield – 2.5% 1.8%
Shareholder yield – 2.5% 1.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNAIQVCRL
Forward P/E – 23.0xFY2026 34.3xFY2026
EPS, next fiscal year $-4.06FY2026 $12.14FY2026 $10.90FY2026
EPS growth, next FY – +1.8%FY2026 +6.0%FY2026
EPS growth, the year after – +13.3% +20.5%
Revenue, next fiscal year $88.21MFY2026 $18.58BFY2026 $3.82BFY2026
Revenue growth, next FY -48.2%FY2026 +13.9%FY2026 -4.9%FY2026
Revenue growth, the year after +5.8% -3.5% +0.7%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNAIQVCRL
Held by institutions 55.2% 94.1% 100.0%
Institutions holding 182 1,083 570
Change in shares held, QoQ +12.3% +0.3% -0.7%
Institutions buying 100 530 270
Institutions selling 39 424 204
Buyers to sellers 2.56 1.25 1.32

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNAIQVCRL
DNA 1.00 0.21 0.35
IQV 0.21 1.00 0.71
CRL 0.35 0.71 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, IQV and CRL?

Iqvia Holdings (IQV) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $795.12M, Iqvia Holdings (IQV) $45.19B, Charles River Laboratories International (CRL) $18.05B.

Which company is growing faster?

Iqvia Holdings (IQV) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Iqvia Holdings (IQV) +8.8%, Charles River Laboratories International (CRL) -0.7%.

Which company is more profitable?

Iqvia Holdings (IQV) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Iqvia Holdings (IQV) 8.1%, Charles River Laboratories International (CRL) -6.0%). On return on invested capital, Iqvia Holdings (IQV) leads (Iqvia Holdings (IQV) 8.2%, Charles River Laboratories International (CRL) 1.6%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Ginkgo Bioworks Holdings (DNA) +4.8%, Iqvia Holdings (IQV) +27.9%, Charles River Laboratories International (CRL) +99.1%. Over five years, Iqvia Holdings (IQV) compounded fastest (Ginkgo Bioworks Holdings (DNA) -52.5%/yr, Iqvia Holdings (IQV) +1.3%/yr, Charles River Laboratories International (CRL) -3.6%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Iqvia Holdings (IQV) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 102.8%, Iqvia Holdings (IQV) 40.4%, Charles River Laboratories International (CRL) 45.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, IQV and CRL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iqvia Holdings (IQV) leads on 9. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.