DNA vs GH vs LH Stock Comparison

Ginkgo Bioworks Holdings, Guardant Health and Labcorp Holdings Prices as of Oct 27, 2026 Peers: Industry group
GH Guardant Health, Inc.
$178.06 +0.5% 1M +151.3% 1Y
Market cap
$24.48B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
3 wins
LH Labcorp Holdings Inc.
$331.39 +7.1% 1M +20.2% 1Y
Market cap
$29.52B
P/E
29.5x
Revenue (TTM)
$14.35B
Div. yield
–
Diagnostic Labs Healthcare
4 wins

Head to Head

7 decided of 12

Labcorp Holdings leads on 4 of the 12 questions below (Labcorp Holdings 4, Guardant Health 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDNAGHLHLeader
Larger companyMarket capitalisation $787.05M $24.48B $29.52B LH
Cheaper on earningsLower P/E, profitable companies only -2.7x -54.0x 29.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 19.4x –
Faster revenue growthRevenue growth, trailing twelve months -46.8% +42.7% +6.4% GH
More profitableNet margin, trailing twelve months -260.0% -38.3% 7.0% LH
Better return on capitalReturn on invested capital — — 8.2% –
Less leveragedLower net debt / EBITDA — — 2.6x –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -15.8% +151.3% +20.2% GH
Better 5-year returnAnnualised price return, 5 years -54.4%/yr +8.5%/yr +6.2%/yr GH
Less volatileAnnualised volatility, 1 year 101.5% 57.4% 24.0% LH
Higher overall scoreMean of the five percentile scores vs peers 43/100 28/100 56/100 LH

Percentile Scorecard

DNAGHLH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDNAGHLH
Valuation 10 #10 of 11 18 #76 of 92 62 #36 of 92
Growth 50 #6 of 11 49 #45 of 87 30 #61 of 87
Profitability 10 #10 of 11 7 #80 of 86 68 #28 of 86
Financial Health 100 #1 of 13 52 #47 of 97 47 #52 of 97
Shareholder Returns – 15 #48 of 56 73 #16 of 56
Overall 43 28 56
  • DNA ranked among 13 companies in Pharma Services
  • GH ranked among 102 companies in Healthcare Providers
  • LH ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDNAGHLHSPY
1 month +5.7%+0.5%+7.1% -0.2%
3 months +46.4%+24.0%+5.4% +3.9%
6 months +43.6%+114.3%+27.7% +8.2%
Year to date +35.6%+74.3%+32.1% +12.9%
1 year -15.8%+151.3%+20.2% +12.3%
3 years -79.1%+613.4%+66.6% +87.4%
3 years, per year -40.7%+92.6%+18.6% +23.3%
5 years -98.0%+50.7%+35.2% +67.9%
5 years, per year -54.4%+8.5%+6.2% +10.9%
10 years ——+211.2% +261.1%
10 years, per year ——+12.0% +13.7%

Risk

MeasureDNAGHLHSPY
Volatility, 1Y 101.5%57.4%24.0% 12.7%
Downside volatility, 1Y 103.1%48.7%24.1% 12.7%
Beta vs S&P 500, 1Y 3.031.030.34 1.00
Return / volatility, 1Y -0.162.640.84 0.97
Max drawdown, 5Y -99.1%-86.7%-35.0% -25.4%
From 52-week high -24.8%-4.9%-2.4% -1.2%
52-week high $14.98$187.22$339.40 $779.14
52-week low $5.48$69.58$246.64 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDNAGHLH
P/E now vs peer median -2.4xmedian 32.1x -52.2xmedian 24.6x 27.0xmedian 24.6x
P/S now vs peer median 6.4xmedian 2.6x 20.1xmedian 1.6x 1.9xmedian 1.6x
EV/EBITDA now vs peer median -2.7xmedian 38.1x -52.7xmedian 14.6x 14.8xmedian 14.6x
P/FCF now vs peer median -4.1xmedian 21.5x -98.8xmedian 21.6x 23.2xmedian 21.6x
P/B now vs peer median 1.7xmedian 3.1x -106.8xmedian 3.2x 3.1xmedian 3.2x
PEG now vs peer median 0.02median 2.03 -5.25median 0.66 2.87median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDNAGHLH
Revenue $111.86M $1.18B $14.35B
Gross profit $92.92M $769.16M $4.14B
Operating income -$290.69M -$470.26M $1.50B
Net income -$290.80M -$453.44M $1.00B
Free cash flow -$174.80M -$240.72M $1.16B
R&D $215.61M $375.79M –
EPS (diluted) $-5.24 $-3.41 $12.22
Cash & equivalents $84.54M $1.05B $141.80M
Total debt – – $5.86B
Shares (diluted) 55.46M 132.87M 82.00M
Enterprise value $24.96M $20.55B $27.27B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDNAGHLH
P/E -2.4x -52.2x 27.0x
P/FCF -4.1x -98.8x 23.2x
P/Operating cash flow -4.2x -128.5x 16.4x
P/S 6.4x 20.1x 1.9x
P/B 1.7x -106.8x 3.1x
P/Tangible book 1.9x -95.9x 5.4x
EV/EBITDA -2.7x -52.7x 14.8x
EV/EBIT -2.2x -48.4x 21.7x
EV/Revenue 5.7x 19.2x 2.3x
EV/FCF -3.6x -94.5x 28.2x
EV/Operating cash flow -3.7x -122.8x 19.9x
PEG (3Y EPS CAGR) 0.02 -5.25 2.87

Growth

14 metrics
MetricDNAGHLH
Revenue growth (1Y) -46.8% 42.7% 6.4%
Revenue CAGR (3Y) -30.0% 32.4% 6.5%
Gross profit growth (1Y) -49.3% 47.7% 9.2%
Gross profit CAGR (3Y) -28.2% – 7.1%
Operating income growth (1Y) 2.4% -2.1% 25.6%
Operating income CAGR (3Y) 39.1% 4.8% 14.4%
Net income growth (1Y) 7.7% -9.6% 31.3%
Net income CAGR (3Y) 38.0% 3.7% 6.5%
EPS growth (1Y) 8.7% -2.4% 34.3%
EPS CAGR (3Y) -102.3% 9.9% 9.4%
Operating cash flow growth (1Y) 28.4% 22.4% -3.3%
Operating cash flow CAGR (3Y) 16.9% 18.1% 3.0%
Free cash flow growth (1Y) 36.2% 11.4% -8.4%
Free cash flow CAGR (3Y) 22.1% 14.4% 0.5%

Profitability

14 metrics
MetricDNAGHLH
Gross margin 83.1% 65.0% 28.9%
EBITDA margin -211.6% -36.5% 15.3%
Operating margin -259.9% -39.7% 10.4%
Pretax margin -264.1% -38.4% 8.6%
Net margin -260.0% -38.3% 7.0%
FCF margin -156.3% -20.3% 8.1%
Operating cash flow margin -152.2% -15.7% 11.4%
Return on equity -67.4% – 11.6%
Return on assets -28.7% -23.7% 5.3%
Return on invested capital – – 8.2%
Return on capital employed -31.0% -29.9% 9.0%
Asset turnover 0.1x 0.6x 0.8x
Cash conversion (OCF / net income) 0.6x 0.4x 1.6x
Stock comp / revenue 61.5% 16.2% 0.9%

Financial Health

11 metrics
MetricDNAGHLH
Debt / assets – – 31.6%
Debt / equity – – 0.7x
Net debt / EBITDA – – 2.6x
Debt / FCF – – 5.1x
Liabilities / assets 57.5% 111.7% 53.6%
Equity / assets 42.5% -11.7% 46.4%
Interest coverage – -97.6x 6.6x
Current ratio 4.6x 4.0x 1.8x
Quick ratio 1.4x 3.5x 1.2x
Cash ratio 1.2x 3.1x 0.1x
Altman Z-score -8.66 4.77 3.43

Shareholder Returns

7 metrics
MetricDNAGHLH
Dividend yield – – 0.9%
Net buyback yield – -1.7% 2.4%
Shareholder yield – -1.7% 3.3%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDNAGHLH
Forward P/E – – 19.4xFY2026
EPS, next fiscal year $-4.06FY2026 $-3.33FY2026 $17.07FY2026
EPS growth, next FY – – +3.8%FY2026
EPS growth, the year after – – +9.3%
Revenue, next fiscal year $88.21MFY2026 $1.42BFY2026 $14.31BFY2026
Revenue growth, next FY -48.2%FY2026 +44.5%FY2026 +2.6%FY2026
Revenue growth, the year after +5.8% +27.0% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDNAGHLH
Held by institutions 55.2% 100.0% 97.0%
Institutions holding 182 594 1,051
Change in shares held, QoQ +12.3% -2.6% +1.6%
Institutions buying 100 353 465
Institutions selling 39 180 393
Buyers to sellers 2.56 1.96 1.18

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DNAGHLH
DNA 1.00 0.34 0.10
GH 0.34 1.00 0.24
LH 0.10 0.24 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DNA, GH and LH?

Labcorp Holdings (LH) is the largest by market capitalisation: Ginkgo Bioworks Holdings (DNA) $787.05M, Guardant Health (GH) $24.48B, Labcorp Holdings (LH) $29.52B.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Ginkgo Bioworks Holdings (DNA) -46.8%, Guardant Health (GH) +42.7%, Labcorp Holdings (LH) +6.4%.

Which company is more profitable?

Labcorp Holdings (LH) has the highest net margin (Ginkgo Bioworks Holdings (DNA) -260.0%, Guardant Health (GH) -38.3%, Labcorp Holdings (LH) 7.0%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Ginkgo Bioworks Holdings (DNA) -15.8%, Guardant Health (GH) +151.3%, Labcorp Holdings (LH) +20.2%. Over five years, Guardant Health (GH) compounded fastest (Ginkgo Bioworks Holdings (DNA) -54.4%/yr, Guardant Health (GH) +8.5%/yr, Labcorp Holdings (LH) +6.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Labcorp Holdings (LH) has been the steadiest (Ginkgo Bioworks Holdings (DNA) 101.5%, Guardant Health (GH) 57.4%, Labcorp Holdings (LH) 24.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DNA, GH and LH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Labcorp Holdings (LH) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.