DHR vs TXG vs SGMOQ Stock Comparison

Danaher, 10x Genomics and Sangamo Therapeutics Prices as of Oct 26, 2026 Peers: Industry group
DHR Danaher Corp /De/
$232.95 +3.7% 1M +4.5% 1Y
Market cap
$162.86B
P/E
40.7x
Revenue (TTM)
$25.11B
Div. yield
–
Life Sciences Tools Healthcare
5 wins
TXG 10x Genomics, Inc.
$72.96 -14.9% 1M +429.8% 1Y
Market cap
$9.40B
P/E
–
Revenue (TTM)
$616.91M
Div. yield
–
Life Sciences Tools Healthcare
2 wins

Head to Head

7 decided of 12

Danaher leads on 5 of the 12 questions below (Danaher 5, 10x Genomics 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionDHRTXGSGMOQLeader
Larger companyMarket capitalisation $162.86B $9.40B $33.62M DHR
Cheaper on earningsLower P/E, profitable companies only 40.7x -125.1x -0.3x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 25.8x — — –
Faster revenue growthRevenue growth, trailing twelve months +4.6% -4.3% -31.6% DHR
More profitableNet margin, trailing twelve months 15.9% -12.2% -310.8% DHR
Better return on capitalReturn on invested capital 5.7% — — –
Less leveragedLower net debt / EBITDA 2.9x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% — –
Better 1-year returnPrice return, last 12 months +4.5% +429.8% -81.8% TXG
Better 5-year returnAnnualised price return, 5 years -5.3%/yr -14.4%/yr -57.2%/yr DHR
Less volatileAnnualised volatility, 1 year 30.7% 73.8% 182.8% DHR
Higher overall scoreMean of the five percentile scores vs peers 59/100 61/100 25/100 TXG

Percentile Scorecard

DHRTXGSGMOQ

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisDHRTXGSGMOQ
Valuation 67 #75 of 228 43 #130 of 228 9 #571 of 626
Growth 21 #176 of 221 66 #76 of 221 43 #348 of 604
Profitability 88 #26 of 208 63 #77 of 208 43 #315 of 555
Financial Health 46 #130 of 239 68 #78 of 239 4 #630 of 658
Shareholder Returns 76 #34 of 137 67 #46 of 137 –
Overall 59 61 25
  • DHR ranked among 248 companies in Medical Devices and Diagnostics
  • TXG ranked among 248 companies in Medical Devices and Diagnostics
  • SGMOQ ranked among 673 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodDHRTXGSGMOQSPY
1 month +3.7%-14.9%-20.0% -0.8%
3 months +18.5%+58.9%+71.4% +3.5%
6 months +29.0%+227.5%-36.8% +7.0%
Year to date +1.8%+347.3%-71.4% +12.2%
1 year +4.5%+429.8%-81.8% +13.0%
3 years +24.0%+100.4%-75.5% +86.3%
3 years, per year +7.4%+26.1%-37.5% +23.1%
5 years -23.7%-54.1%-98.6% +68.6%
5 years, per year -5.3%-14.4%-57.2% +11.0%
10 years +199.7%—-97.0% +258.0%
10 years, per year +11.6%—-29.5% +13.6%

Risk

MeasureDHRTXGSGMOQSPY
Volatility, 1Y 30.7%73.8%182.8% 12.7%
Downside volatility, 1Y 31.8%66.1%253.6% 12.7%
Beta vs S&P 500, 1Y 0.452.212.05 1.00
Return / volatility, 1Y 0.155.82-0.45 1.02
Max drawdown, 5Y -50.8%-96.1%-99.6% -25.4%
From 52-week high -3.8%-25.4%-81.8% -1.8%
52-week high $242.05$97.74$0.66 $779.14
52-week low $161.91$12.44$0.04 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleDHRTXGSGMOQ
P/E now vs peer median 41.0xmedian 30.6x -126.2xmedian 30.6x -0.3xmedian 17.1x
P/S now vs peer median 6.5xmedian 3.0x 15.4xmedian 3.0x 0.9xmedian 8.8x
EV/EBITDA now vs peer median 24.3xmedian 17.5x -212.9xmedian 17.5x -0.1xmedian 17.1x
P/FCF now vs peer median 30.0xmedian 23.3x 78.3xmedian 23.3x -0.3xmedian 18.0x
P/B now vs peer median 3.1xmedian 2.4x 11.5xmedian 2.4x -2.4xmedian 2.1x
PEG now vs peer median -3.28median 0.87 -4.70median 0.87 -0.01median 0.31

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsDHRTXGSGMOQ
Revenue $25.11B $616.91M $39.55M
Gross profit $14.69B $432.03M –
Operating income $5.13B -$88.38M -$121.24M
Net income $4.00B -$75.13M -$122.93M
Free cash flow $5.47B $121.44M -$97.29M
R&D $1.62B $226.80M $112.67M
EPS (diluted) $5.66 $-0.58 $-0.44
Cash & equivalents $4.35B – $20.95M
Total debt $26.56B – –
Shares (diluted) 707.60M 129.98M 280.20M
Enterprise value $146.67B $9.20B -$80.48M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricDHRTXGSGMOQ
P/E 41.0x -126.2x -0.3x
P/FCF 30.0x 78.3x -0.3x
P/Operating cash flow 24.7x 74.8x -0.3x
P/S 6.5x 15.4x 0.9x
P/B 3.1x 11.5x -2.4x
P/Tangible book 5.2x 12.4x -2.4x
EV/EBITDA 24.3x -212.9x -0.1x
EV/EBIT 36.3x -107.0x -0.1x
EV/Revenue 7.4x 15.3x 0.3x
EV/FCF 34.0x 77.9x -0.1x
EV/Operating cash flow 28.0x 74.4x -0.1x
PEG (3Y EPS CAGR) -3.28 -4.70 -0.01

Growth

14 metrics
MetricDHRTXGSGMOQ
Revenue growth (1Y) 4.6% -4.3% -31.6%
Revenue CAGR (3Y) -0.5% 2.8% -29.2%
Gross profit growth (1Y) 2.6% -3.5% –
Gross profit CAGR (3Y) -0.9% 1.1% –
Operating income growth (1Y) 16.1% 12.1% -16.6%
Operating income CAGR (3Y) -7.1% 20.9% 15.5%
Net income growth (1Y) 17.3% 11.2% -25.5%
Net income CAGR (3Y) -14.3% 24.2% 13.9%
EPS growth (1Y) 19.2% 14.9% 10.8%
EPS CAGR (3Y) -12.5% 26.8% 29.4%
Operating cash flow growth (1Y) 7.6% 89.8% -44.8%
Operating cash flow CAGR (3Y) -7.6% 135.5% 24.2%
Free cash flow growth (1Y) 12.4% 113.5% -44.3%
Free cash flow CAGR (3Y) -9.0% 44.7% 26.4%

Profitability

14 metrics
MetricDHRTXGSGMOQ
Gross margin 58.5% 70.0% –
EBITDA margin 30.5% -7.2% -296.4%
Operating margin 20.4% -14.3% -306.5%
Pretax margin 19.0% -12.1% -312.2%
Net margin 15.9% -12.2% -310.8%
FCF margin 21.8% 19.7% -246.0%
Operating cash flow margin 26.4% 20.6% -245.8%
Return on equity 7.6% -9.2% –
Return on assets 4.5% -7.3% -165.7%
Return on invested capital 5.7% – –
Return on capital employed 6.4% -9.8% -382.1%
Asset turnover 0.3x 0.6x 0.5x
Cash conversion (OCF / net income) 1.7x -1.7x 0.8x
Stock comp / revenue 1.2% 16.0% 23.0%

Financial Health

11 metrics
MetricDHRTXGSGMOQ
Debt / assets 28.8% – –
Debt / equity 0.5x – –
Net debt / EBITDA 2.9x – –
Debt / FCF 4.9x – –
Liabilities / assets 43.1% 19.9% 123.9%
Equity / assets 56.9% 80.1% -23.9%
Interest coverage 17.6x – –
Current ratio 1.7x 5.7x 0.8x
Quick ratio 1.0x 0.8x 0.5x
Cash ratio 0.5x 0.4x 0.5x
Altman Z-score 3.72 26.75 -44.03

Shareholder Returns

7 metrics
MetricDHRTXGSGMOQ
Dividend yield 0.7% – –
Net buyback yield 1.8% -0.1% -220.1%
Shareholder yield 2.4% -0.1% -220.1%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusDHRTXGSGMOQ
Forward P/E 25.8xFY2026 – –
EPS, next fiscal year $9.03FY2026 $-0.78FY2026 $-0.31FY2026
EPS growth, next FY +15.8%FY2026 – –
EPS growth, the year after +8.9% – –
Revenue, next fiscal year $27.12BFY2026 $580.49MFY2026 $9.62MFY2026
Revenue growth, next FY +10.4%FY2026 -9.7%FY2026 -75.7%FY2026
Revenue growth, the year after -1.6% +24.6% +606.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersDHRTXGSGMOQ
Held by institutions 81.9% 100.0% –
Institutions holding 2,115 389 –
Change in shares held, QoQ +1.1% +2.4% –
Institutions buying 837 197 –
Institutions selling 1,015 137 –
Buyers to sellers 0.82 1.44 –

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

DHRTXGSGMOQ
DHR 1.00 0.33 0.02
TXG 0.33 1.00 0.13
SGMOQ 0.02 0.13 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, DHR, TXG and SGMOQ?

Danaher (DHR) is the largest by market capitalisation: Danaher (DHR) $162.86B, 10x Genomics (TXG) $9.40B, Sangamo Therapeutics (SGMOQ) $33.62M.

Which company is growing faster?

Danaher (DHR) grew revenue fastest over the trailing twelve months: Danaher (DHR) +4.6%, 10x Genomics (TXG) -4.3%, Sangamo Therapeutics (SGMOQ) -31.6%.

Which company is more profitable?

Danaher (DHR) has the highest net margin (Danaher (DHR) 15.9%, 10x Genomics (TXG) -12.2%, Sangamo Therapeutics (SGMOQ) -310.8%).

Which stock has performed better?

Over the past year 10x Genomics (TXG) returned the most: Danaher (DHR) +4.5%, 10x Genomics (TXG) +429.8%, Sangamo Therapeutics (SGMOQ) -81.8%. Over five years, Danaher (DHR) compounded fastest (Danaher (DHR) -5.3%/yr, 10x Genomics (TXG) -14.4%/yr, Sangamo Therapeutics (SGMOQ) -57.2%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Danaher (DHR) has been the steadiest (Danaher (DHR) 30.7%, 10x Genomics (TXG) 73.8%, Sangamo Therapeutics (SGMOQ) 182.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, DHR, TXG and SGMOQ?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Danaher (DHR) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.