CRL vs TMO vs IQV Stock Comparison

Charles River Laboratories International, Thermo Fisher Scientific and Iqvia Holdings Prices as of Oct 26, 2026 Peers: Industry group
IQV Iqvia Holdings Inc.
$274.30 +1.7% 1M +24.4% 1Y
Market cap
$46.61B
P/E
33.9x
Revenue (TTM)
$16.98B
Div. yield
–
Contract Research Healthcare
6 wins

Head to Head

11 decided of 12

Iqvia Holdings leads on 6 of the 12 questions below (Iqvia Holdings 6, Thermo Fisher Scientific 4, Charles River Laboratories International 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCRLTMOIQVLeader
Larger companyMarket capitalisation $17.13B $254.21B $46.61B TMO
Cheaper on earningsLower P/E, profitable companies only -71.8x 35.9x 33.9x IQV
Cheaper on forward earningsLower price / next fiscal year consensus EPS 32.8x 26.6x 22.6x IQV
Faster revenue growthRevenue growth, trailing twelve months -0.7% +8.3% +8.2% TMO
More profitableNet margin, trailing twelve months -6.0% — 8.1% IQV
Better return on capitalReturn on invested capital 1.6% — 8.3% IQV
Less leveragedLower net debt / EBITDA 6.3x — 4.1x IQV
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +81.4% +19.6% +24.4% CRL
Better 5-year returnAnnualised price return, 5 years -3.6%/yr +2.3%/yr +1.5%/yr TMO
Less volatileAnnualised volatility, 1 year 46.0% 29.9% 40.4% TMO
Higher overall scoreMean of the five percentile scores vs peers 45/100 51/100 65/100 IQV

Percentile Scorecard

CRLTMOIQV

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCRLTMOIQV
Valuation 60 #5 of 11 49 #116 of 228 80 #3 of 11
Growth 10 #10 of 11 40 #133 of 221 80 #3 of 11
Profitability 70 #4 of 11 70 #63 of 208 90 #2 of 11
Financial Health 42 #8 of 13 – 8 #12 of 13
Shareholder Returns – 44 #77 of 137 –
Overall 45 51 65
  • CRL ranked among 13 companies in Pharma Services
  • TMO ranked among 248 companies in Medical Devices and Diagnostics
  • IQV ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCRLTMOIQVSPY
1 month +21.9%+1.7%+1.7% -0.8%
3 months +59.4%+22.4%+28.5% +3.5%
6 months +108.7%+46.3%+67.4% +7.0%
Year to date +79.1%+18.2%+21.7% +12.2%
1 year +81.4%+19.6%+24.4% +13.0%
3 years +107.1%+58.7%+52.4% +86.3%
3 years, per year +27.5%+16.7%+15.1% +23.1%
5 years -16.9%+11.8%+7.9% +68.6%
5 years, per year -3.6%+2.3%+1.5% +11.0%
10 years +358.2%+362.6%+275.1% +258.0%
10 years, per year +16.4%+16.6%+14.1% +13.6%

Risk

MeasureCRLTMOIQVSPY
Volatility, 1Y 46.0%29.9%40.4% 12.7%
Downside volatility, 1Y 43.0%28.3%39.4% 12.7%
Beta vs S&P 500, 1Y 1.270.620.74 1.00
Return / volatility, 1Y 1.770.660.60 1.02
Max drawdown, 5Y -77.8%-41.5%-51.5% -25.4%
From 52-week high 0.0%-1.7%-1.8% -1.8%
52-week high $357.35$696.55$279.38 $779.14
52-week low $149.93$438.34$156.66 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCRLTMOIQV
P/E now vs peer median -72.0xmedian 36.5x 35.9xmedian 30.6x 33.1xmedian 36.5x
P/S now vs peer median 4.3xmedian 2.7x 5.3xmedian 3.0x 2.7xmedian 2.7x
EV/EBITDA now vs peer median 50.2xmedian 37.7x —median 17.5x 17.3xmedian 37.7x
P/FCF now vs peer median 46.0xmedian 20.7x 34.0xmedian 23.3x 20.7xmedian 20.7x
P/B now vs peer median 6.0xmedian 2.9x 4.6xmedian 2.4x 7.2xmedian 2.9x
PEG now vs peer median 1.99median 2.04 4.74median 0.87 2.79median 2.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCRLTMOIQV
Revenue $4.00B $47.35B $16.98B
Gross profit $1.31B – $5.60B
Operating income $90.14M $8.47B $2.20B
Net income -$239.23M $7.09B $1.38B
Free cash flow $370.61M – $2.18B
R&D – $1.40B –
EPS (diluted) $-4.97 $19.06 $8.22
Cash & equivalents $192.03M $5.46B $1.91B
Total debt $2.62B – $16.00B
Shares (diluted) 48.02M 371.00M 167.30M
Enterprise value $16.32B $254.21B $38.31B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCRLTMOIQV
P/E -72.0x 35.9x 33.1x
P/FCF 46.0x 34.0x 20.7x
P/Operating cash flow 29.3x 27.2x 16.0x
P/S 4.3x 5.3x 2.7x
P/B 6.0x 4.6x 7.2x
P/Tangible book 6.6x 6.9x 29.1x
EV/EBITDA 50.2x – 17.3x
EV/EBIT 216.1x – 26.8x
EV/Revenue 4.9x 5.3x 3.5x
EV/FCF 52.6x – 27.0x
EV/Operating cash flow 33.5x 27.2x 21.0x
PEG (3Y EPS CAGR) 1.99 4.74 2.79

Growth

14 metrics
MetricCRLTMOIQV
Revenue growth (1Y) -0.7% 8.3% 8.2%
Revenue CAGR (3Y) -1.5% 2.9% 5.0%
Gross profit growth (1Y) -0.1% – 4.1%
Gross profit CAGR (3Y) -5.5% – 3.1%
Operating income growth (1Y) -27.6% 12.8% 1.0%
Operating income CAGR (3Y) -48.2% 7.2% 6.0%
Net income growth (1Y) -268.7% 7.9% 11.5%
Net income CAGR (3Y) -35.5% 6.2% 7.8%
EPS growth (1Y) -253.8% 9.7% 15.1%
EPS CAGR (3Y) -36.2% 7.6% 11.9%
Operating cash flow growth (1Y) -26.1% 21.9% 7.7%
Operating cash flow CAGR (3Y) -2.3% 4.5% 7.9%
Free cash flow growth (1Y) -35.9% – 8.7%
Free cash flow CAGR (3Y) 8.6% – 11.3%

Profitability

14 metrics
MetricCRLTMOIQV
Gross margin 32.7% – 33.0%
EBITDA margin 9.7% – 20.1%
Operating margin 2.3% – 13.0%
Pretax margin -4.6% – 9.3%
Net margin -6.0% – 8.1%
FCF margin 9.3% – 12.9%
Operating cash flow margin 14.6% 19.7% 16.6%
Return on equity -8.2% 13.2% 21.8%
Return on assets -3.1% 6.2% 4.6%
Return on invested capital 1.6% – 8.3%
Return on capital employed 1.4% – 10.5%
Asset turnover 0.5x 0.4x 0.6x
Cash conversion (OCF / net income) -2.4x 1.3x 2.0x
Stock comp / revenue 2.1% – 1.6%

Financial Health

11 metrics
MetricCRLTMOIQV
Debt / assets 34.8% – 53.5%
Debt / equity 0.9x – 2.5x
Net debt / EBITDA 6.3x – 4.1x
Debt / FCF 7.1x – 7.3x
Liabilities / assets 62.2% – 78.9%
Equity / assets 37.8% 47.9% 21.1%
Interest coverage 0.8x – 2.9x
Current ratio 1.3x 1.8x 0.7x
Quick ratio 0.8x – 0.8x
Cash ratio 0.2x – 0.2x
Altman Z-score 3.07 – 2.23

Shareholder Returns

7 metrics
MetricCRLTMOIQV
Dividend yield – 0.3% –
Net buyback yield 1.9% – 2.6%
Shareholder yield 1.9% 0.3% 2.6%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCRLTMOIQV
Forward P/E 32.8xFY2026 26.6xFY2026 22.6xFY2026
EPS, next fiscal year $10.90FY2026 $25.77FY2026 $12.14FY2026
EPS growth, next FY +6.0%FY2026 +12.7%FY2026 +1.8%FY2026
EPS growth, the year after +20.5% +1.8% +13.3%
Revenue, next fiscal year $3.82BFY2026 $50.00BFY2026 $18.58BFY2026
Revenue growth, next FY -4.9%FY2026 +12.2%FY2026 +13.9%FY2026
Revenue growth, the year after +0.7% -2.9% -3.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCRLTMOIQV
Held by institutions 100.0% 90.2% 94.1%
Institutions holding 570 2,621 1,083
Change in shares held, QoQ -0.7% +0.8% +0.3%
Institutions buying 270 1,141 530
Institutions selling 204 1,144 424
Buyers to sellers 1.32 1.00 1.25

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CRLTMOIQV
CRL 1.00 0.64 0.70
TMO 0.64 1.00 0.67
IQV 0.70 0.67 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CRL, TMO and IQV?

Thermo Fisher Scientific (TMO) is the largest by market capitalisation: Charles River Laboratories International (CRL) $17.13B, Thermo Fisher Scientific (TMO) $254.21B, Iqvia Holdings (IQV) $46.61B.

Which stock is cheaper, CRL, TMO and IQV?

Iqvia Holdings (IQV) trades on the lowest price-to-earnings ratio (Charles River Laboratories International (CRL) -71.8x, Thermo Fisher Scientific (TMO) 35.9x, Iqvia Holdings (IQV) 33.9x). On next year's consensus earnings, Iqvia Holdings (IQV) is cheapest (Charles River Laboratories International (CRL) 32.8x, Thermo Fisher Scientific (TMO) 26.6x, Iqvia Holdings (IQV) 22.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Thermo Fisher Scientific (TMO) grew revenue fastest over the trailing twelve months: Charles River Laboratories International (CRL) -0.7%, Thermo Fisher Scientific (TMO) +8.3%, Iqvia Holdings (IQV) +8.2%.

Which company is more profitable?

Iqvia Holdings (IQV) has the highest net margin (Charles River Laboratories International (CRL) -6.0%, Iqvia Holdings (IQV) 8.1%). On return on invested capital, Iqvia Holdings (IQV) leads (Charles River Laboratories International (CRL) 1.6%, Iqvia Holdings (IQV) 8.3%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Charles River Laboratories International (CRL) +81.4%, Thermo Fisher Scientific (TMO) +19.6%, Iqvia Holdings (IQV) +24.4%. Over five years, Thermo Fisher Scientific (TMO) compounded fastest (Charles River Laboratories International (CRL) -3.6%/yr, Thermo Fisher Scientific (TMO) +2.3%/yr, Iqvia Holdings (IQV) +1.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Thermo Fisher Scientific (TMO) has been the steadiest (Charles River Laboratories International (CRL) 46.0%, Thermo Fisher Scientific (TMO) 29.9%, Iqvia Holdings (IQV) 40.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CRL, TMO and IQV?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Iqvia Holdings (IQV) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.