CRL vs LH vs DNA Stock Comparison

Charles River Laboratories International, Labcorp Holdings and Ginkgo Bioworks Holdings Prices as of Oct 29, 2026 Peers: Industry group
LH Labcorp Holdings Inc.
$368.15 +19.2% 1M +48.4% 1Y
Market cap
$30.11B
P/E
30.0x
Revenue (TTM)
$14.59B
Div. yield
–
Diagnostic Labs Healthcare
6 wins

Head to Head

8 decided of 12

Labcorp Holdings leads on 6 of the 12 questions below (Labcorp Holdings 6, Charles River Laboratories International 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCRLLHDNALeader
Larger companyMarket capitalisation $17.78B $30.11B $755.38M LH
Cheaper on earningsLower P/E, profitable companies only -74.6x 30.0x -2.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 34.5x 21.6x — LH
Faster revenue growthRevenue growth, trailing twelve months -0.7% +6.0% -46.8% LH
More profitableNet margin, trailing twelve months -6.0% — -260.0% CRL
Better return on capitalReturn on invested capital 1.6% — — –
Less leveragedLower net debt / EBITDA 6.3x — — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +108.6% +48.4% +4.5% CRL
Better 5-year returnAnnualised price return, 5 years -3.5%/yr +8.4%/yr -53.0%/yr LH
Less volatileAnnualised volatility, 1 year 45.7% 24.3% 102.8% LH
Higher overall scoreMean of the five percentile scores vs peers 43/100 57/100 43/100 LH

Percentile Scorecard

CRLLHDNA

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCRLLHDNA
Valuation 50 #6 of 11 58 #39 of 92 10 #10 of 11
Growth 10 #10 of 11 35 #57 of 87 50 #6 of 11
Profitability 70 #4 of 11 71 #26 of 86 10 #10 of 11
Financial Health 42 #8 of 13 56 #43 of 97 100 #1 of 13
Shareholder Returns – 65 #20 of 55 –
Overall 43 57 43
  • CRL ranked among 13 companies in Pharma Services
  • LH ranked among 102 companies in Healthcare Providers
  • DNA ranked among 13 companies in Pharma Services

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCRLLHDNASPY
1 month +26.8%+19.2%+6.4% +0.7%
3 months +60.2%+16.6%+57.7% +3.7%
6 months +125.1%+43.4%+50.6% +7.1%
Year to date +88.4%+46.7%+53.3% +12.8%
1 year +108.6%+48.4%+4.5% +11.9%
3 years +128.4%+85.8%-76.1% +85.2%
3 years, per year +31.7%+23.0%-37.9% +22.8%
5 years -16.2%+49.3%-97.7% +67.6%
5 years, per year -3.5%+8.4%-53.0% +10.9%
10 years +394.5%+245.6%— +262.0%
10 years, per year +17.3%+13.2%— +13.7%

Risk

MeasureCRLLHDNASPY
Volatility, 1Y 45.7%24.3%102.8% 12.7%
Downside volatility, 1Y 42.5%21.7%103.3% 12.6%
Beta vs S&P 500, 1Y 1.280.363.07 1.00
Return / volatility, 1Y 2.381.990.04 0.94
Max drawdown, 5Y -77.3%-35.0%-99.1% -25.4%
From 52-week high 0.0%0.0%-15.0% -1.2%
52-week high $375.83$368.15$14.98 $779.14
52-week low $149.93$246.64$5.48 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCRLLHDNA
P/E now vs peer median -75.7xmedian 36.6x 30.0xmedian 26.0x -2.7xmedian 36.6x
P/S now vs peer median 4.5xmedian 2.6x 2.0xmedian 1.6x 7.3xmedian 2.6x
EV/EBITDA now vs peer median 52.5xmedian 31.1x —median 15.4x -3.1xmedian 31.1x
P/FCF now vs peer median 48.4xmedian 21.8x 21.6xmedian 21.5x -4.6xmedian 21.8x
P/B now vs peer median 6.3xmedian 3.1x 3.4xmedian 3.2x 1.9xmedian 3.1x
PEG now vs peer median 2.09median 2.05 1.74median 0.87 0.03median 2.05

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCRLLHDNA
Revenue $4.00B $14.59B $111.86M
Gross profit $1.31B $4.23B $92.92M
Operating income $90.14M $1.50B -$290.69M
Net income -$239.23M $1.00B -$290.80M
Free cash flow $370.61M – -$174.80M
R&D – – $215.61M
EPS (diluted) $-4.97 $12.24 $-5.24
Cash & equivalents $192.03M $261.80M $84.54M
Total debt $2.62B – –
Shares (diluted) 48.02M 82.00M 55.46M
Enterprise value $16.98B $30.11B -$6.71M

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCRLLHDNA
P/E -75.7x 30.0x -2.7x
P/FCF 48.4x 21.6x -4.6x
P/Operating cash flow 30.8x 16.4x -4.8x
P/S 4.5x 2.0x 7.3x
P/B 6.3x 3.4x 1.9x
P/Tangible book 6.9x 5.8x 2.2x
EV/EBITDA 52.5x – -3.1x
EV/EBIT 225.9x – -2.5x
EV/Revenue 5.1x 2.0x 6.5x
EV/FCF 55.0x – -4.2x
EV/Operating cash flow 35.0x 16.4x -4.3x
PEG (3Y EPS CAGR) 2.09 1.74 0.03

Growth

14 metrics
MetricCRLLHDNA
Revenue growth (1Y) -0.7% 6.0% -46.8%
Revenue CAGR (3Y) -1.5% 6.6% -30.0%
Gross profit growth (1Y) -0.1% 8.0% -49.3%
Gross profit CAGR (3Y) -5.5% 8.2% -28.2%
Operating income growth (1Y) -27.6% 12.6% 2.4%
Operating income CAGR (3Y) -48.2% 19.7% 39.1%
Net income growth (1Y) -268.7% 17.4% 7.7%
Net income CAGR (3Y) -35.5% 14.9% 38.0%
EPS growth (1Y) -253.8% 19.8% 8.7%
EPS CAGR (3Y) -36.2% 17.2% -102.3%
Operating cash flow growth (1Y) -26.1% 0.6% 28.4%
Operating cash flow CAGR (3Y) -2.3% 9.0% 16.9%
Free cash flow growth (1Y) -35.9% – 36.2%
Free cash flow CAGR (3Y) 8.6% – 22.1%

Profitability

14 metrics
MetricCRLLHDNA
Gross margin 32.7% – 83.1%
EBITDA margin 9.7% – -211.6%
Operating margin 2.3% – -259.9%
Pretax margin -4.6% – -264.1%
Net margin -6.0% – -260.0%
FCF margin 9.3% – -156.3%
Operating cash flow margin 14.6% 12.4% -152.2%
Return on equity -8.2% 11.5% -67.4%
Return on assets -3.1% 5.4% -28.7%
Return on invested capital 1.6% – –
Return on capital employed 1.4% – -31.0%
Asset turnover 0.5x 0.8x 0.1x
Cash conversion (OCF / net income) -2.4x 1.8x 0.6x
Stock comp / revenue 2.1% 0.9% 61.5%

Financial Health

11 metrics
MetricCRLLHDNA
Debt / assets 34.8% – –
Debt / equity 0.9x – –
Net debt / EBITDA 6.3x – –
Debt / FCF 7.1x – –
Liabilities / assets 62.2% 53.2% 57.5%
Equity / assets 37.8% 46.8% 42.5%
Interest coverage 0.8x – –
Current ratio 1.3x 1.4x 4.6x
Quick ratio 0.8x – 1.4x
Cash ratio 0.2x – 1.2x
Altman Z-score 3.18 – -8.57

Shareholder Returns

7 metrics
MetricCRLLHDNA
Dividend yield – 0.8% –
Net buyback yield 1.8% – –
Shareholder yield 1.8% 0.8% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCRLLHDNA
Forward P/E 34.5xFY2026 21.6xFY2026 –
EPS, next fiscal year $10.90FY2026 $17.07FY2026 $-4.06FY2026
EPS growth, next FY +6.0%FY2026 +3.8%FY2026 –
EPS growth, the year after +20.5% +9.3% –
Revenue, next fiscal year $3.82BFY2026 $14.31BFY2026 $88.21MFY2026
Revenue growth, next FY -4.9%FY2026 +2.6%FY2026 -48.2%FY2026
Revenue growth, the year after +0.7% +11.9% +5.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCRLLHDNA
Held by institutions 100.0% 97.0% 55.2%
Institutions holding 571 1,052 183
Change in shares held, QoQ -0.7% +1.6% +12.3%
Institutions buying 271 466 100
Institutions selling 204 393 39
Buyers to sellers 1.33 1.19 2.56

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CRLLHDNA
CRL 1.00 0.38 0.35
LH 0.38 1.00 0.14
DNA 0.35 0.14 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CRL, LH and DNA?

Labcorp Holdings (LH) is the largest by market capitalisation: Charles River Laboratories International (CRL) $17.78B, Labcorp Holdings (LH) $30.11B, Ginkgo Bioworks Holdings (DNA) $755.38M.

Which company is growing faster?

Labcorp Holdings (LH) grew revenue fastest over the trailing twelve months: Charles River Laboratories International (CRL) -0.7%, Labcorp Holdings (LH) +6.0%, Ginkgo Bioworks Holdings (DNA) -46.8%.

Which company is more profitable?

Charles River Laboratories International (CRL) has the highest net margin (Charles River Laboratories International (CRL) -6.0%, Ginkgo Bioworks Holdings (DNA) -260.0%).

Which stock has performed better?

Over the past year Charles River Laboratories International (CRL) returned the most: Charles River Laboratories International (CRL) +108.6%, Labcorp Holdings (LH) +48.4%, Ginkgo Bioworks Holdings (DNA) +4.5%. Over five years, Labcorp Holdings (LH) compounded fastest (Charles River Laboratories International (CRL) -3.5%/yr, Labcorp Holdings (LH) +8.4%/yr, Ginkgo Bioworks Holdings (DNA) -53.0%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Labcorp Holdings (LH) has been the steadiest (Charles River Laboratories International (CRL) 45.7%, Labcorp Holdings (LH) 24.3%, Ginkgo Bioworks Holdings (DNA) 102.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CRL, LH and DNA?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Labcorp Holdings (LH) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.