CAI vs SHC vs TEM Stock Comparison

Caris Life Sciences, Sotera Health and Tempus AI Prices as of Oct 26, 2026 Peers: Industry group
SHC Sotera Health Co
$18.39 +0.3% 1M +9.1% 1Y
Market cap
$5.28B
P/E
32.3x
Revenue (TTM)
$1.22B
Div. yield
–
Diagnostic Labs Healthcare
5 wins
TEM Tempus AI, Inc.
$67.16 -21.0% 1M -24.7% 1Y
Market cap
$13.00B
P/E
–
Revenue (TTM)
$1.43B
Div. yield
–
Diagnostic Labs Healthcare
1 win

Head to Head

10 decided of 12

Sotera Health leads on 5 of the 12 questions below (Sotera Health 5, Caris Life Sciences 4, Tempus AI 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionCAISHCTEMLeader
Larger companyMarket capitalisation $9.52B $5.28B $13.00B TEM
Cheaper on earningsLower P/E, profitable companies only 90.5x 32.3x -51.1x SHC
Cheaper on forward earningsLower price / next fiscal year consensus EPS 295.1x 20.0x — SHC
Faster revenue growthRevenue growth, trailing twelve months +85.4% +8.1% +50.4% CAI
More profitableNet margin, trailing twelve months 10.6% 13.4% -17.8% SHC
Better return on capitalReturn on invested capital 15.6% 9.1% -52.0% CAI
Less leveragedLower net debt / EBITDA -2.2x 3.3x — CAI
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +4.5% +9.1% -24.7% SHC
Better 5-year returnAnnualised price return, 5 years — -6.0%/yr — –
Less volatileAnnualised volatility, 1 year 69.6% 28.5% 76.6% SHC
Higher overall scoreMean of the five percentile scores vs peers 69/100 58/100 26/100 CAI

Percentile Scorecard

CAISHCTEM

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisCAISHCTEM
Valuation 23 #72 of 93 50 #47 of 93 9 #85 of 93
Growth 99 #2 of 88 67 #30 of 88 26 #65 of 88
Profitability 87 #12 of 87 80 #18 of 87 11 #78 of 87
Financial Health 82 #19 of 100 35 #65 of 100 57 #44 of 100
Shareholder Returns 53 #27 of 56 – –
Overall 69 58 26
  • CAI ranked among 103 companies in Healthcare Providers
  • SHC ranked among 103 companies in Healthcare Providers
  • TEM ranked among 103 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodCAISHCTEMSPY
1 month +1.5%+0.3%-21.0% -0.8%
3 months +107.7%+6.7%+56.5% +3.5%
6 months +62.9%+16.3%+27.5% +7.0%
Year to date +20.3%+4.3%+13.7% +12.2%
1 year +4.5%+9.1%-24.7% +13.0%
3 years —+47.0%— +86.3%
3 years, per year —+13.7%— +23.1%
5 years —-26.6%— +68.6%
5 years, per year —-6.0%— +11.0%

Risk

MeasureCAISHCTEMSPY
Volatility, 1Y 69.6%28.5%76.6% 12.7%
Downside volatility, 1Y 69.3%27.0%66.8% 12.7%
Beta vs S&P 500, 1Y 1.381.012.54 1.00
Return / volatility, 1Y 0.060.32-0.32 1.02
Max drawdown, 5Y -63.0%-78.2%-59.8% -25.4%
From 52-week high 0.0%-6.0%-26.7% -1.8%
52-week high $32.46$19.57$91.58 $779.14
52-week low $14.55$13.13$41.55 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleCAISHCTEM
P/E now vs peer median 87.3xmedian 25.1x 32.1xmedian 25.1x -47.5xmedian 25.1x
P/S now vs peer median 9.3xmedian 1.6x 4.3xmedian 1.6x 8.2xmedian 1.6x
EV/EBITDA now vs peer median 48.7xmedian 14.5x 13.0xmedian 14.5x —median 14.5x
P/FCF now vs peer median 74.0xmedian 22.4x 46.6xmedian 22.4x -44.7xmedian 22.4x
P/B now vs peer median 15.5xmedian 3.1x 7.9xmedian 3.1x 26.4xmedian 3.1x
PEG now vs peer median —median 0.66 0.86median 0.66 —median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsCAISHCTEM
Revenue $989.61M $1.22B $1.43B
Gross profit $689.36M $668.51M $916.19M
Operating income $153.26M $411.34M -$283.03M
Net income $105.14M $163.48M -$254.43M
Free cash flow $123.96M $112.70M -$263.22M
R&D $117.14M – $196.31M
EPS (diluted) $0.37 $0.57 $-1.39
Cash & equivalents $690.92M $356.72M $599.61M
Total debt $393.15M $2.14B –
Shares (diluted) 282.89M 288.15M 182.40M
Enterprise value $6.34B $3.97B $10.03B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricCAISHCTEM
P/E 87.3x 32.1x -47.5x
P/FCF 74.0x 46.6x -44.7x
P/Operating cash flow 54.4x 18.0x -49.6x
P/S 9.3x 4.3x 8.2x
P/B 15.5x 7.9x 26.4x
P/Tangible book 15.5x 13.3x 88.8x
EV/EBITDA 48.7x 13.0x –
EV/EBIT 57.2x 17.1x -38.7x
EV/Revenue 8.9x 5.8x 7.6x
EV/FCF 70.8x 62.4x -41.6x
EV/Operating cash flow 52.0x 24.1x -46.1x
PEG (3Y EPS CAGR) – 0.86 –

Growth

14 metrics
MetricCAISHCTEM
Revenue growth (1Y) 85.4% 8.1% 50.4%
Revenue CAGR (3Y) – 7.6% –
Gross profit growth (1Y) 141.2% 7.1% 58.5%
Gross profit CAGR (3Y) – 8.1% –
Operating income growth (1Y) 188.2% 21.8% -20.6%
Operating income CAGR (3Y) – 23.2% –
Net income growth (1Y) 137.7% 580.5% -27.4%
Net income CAGR (3Y) – 37.7% –
EPS growth (1Y) 103.0% 574.9% -21.1%
EPS CAGR (3Y) – 37.5% –
Operating cash flow growth (1Y) 227.3% 9.8% -356.2%
Operating cash flow CAGR (3Y) – 61.3% –
Free cash flow growth (1Y) 188.2% 0.0% -278.0%
Free cash flow CAGR (3Y) – 32.6% –

Profitability

14 metrics
MetricCAISHCTEM
Gross margin 69.7% 55.0% 64.0%
EBITDA margin 18.2% 44.6% –
Operating margin 15.5% 33.8% -19.8%
Pretax margin 10.6% 21.7% -17.6%
Net margin 10.6% 13.4% -17.8%
FCF margin 12.5% 9.3% -18.4%
Operating cash flow margin 17.0% 24.0% -16.6%
Return on equity 17.7% 25.4% -57.3%
Return on assets 8.8% 5.0% -11.0%
Return on invested capital 15.6% 9.1% -52.0%
Return on capital employed 15.3% 13.5% -15.2%
Asset turnover 0.8x 0.4x 0.6x
Cash conversion (OCF / net income) 1.6x 1.8x 0.9x
Stock comp / revenue 6.6% 3.1% 13.0%

Financial Health

11 metrics
MetricCAISHCTEM
Debt / assets 32.0% 64.7% –
Debt / equity 0.7x 3.2x –
Net debt / EBITDA -2.2x 3.3x –
Debt / FCF 3.2x 19.0x –
Liabilities / assets 51.9% 79.9% 81.2%
Equity / assets 48.1% 20.1% 18.8%
Interest coverage 3.3x – -5.1x
Current ratio 5.5x 2.8x 3.3x
Quick ratio 4.8x 2.4x 3.1x
Cash ratio 4.1x 1.5x 2.1x
Altman Z-score 7.79 1.93 2.85

Shareholder Returns

7 metrics
MetricCAISHCTEM
Dividend yield – – –
Net buyback yield 0.1% – –
Shareholder yield 0.1% – 0.0%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusCAISHCTEM
Forward P/E 295.1xFY2026 20.0xFY2026 –
EPS, next fiscal year $0.11FY2026 $0.92FY2026 $-0.21FY2026
EPS growth, next FY – +7.0%FY2026 –
EPS growth, the year after +236.4% +21.7% –
Revenue, next fiscal year $1.06BFY2026 $1.33BFY2026 $1.64BFY2026
Revenue growth, next FY +30.1%FY2026 +14.8%FY2026 +29.0%FY2026
Revenue growth, the year after +21.6% -4.2% +24.1%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersCAISHCTEM
Held by institutions 52.0% 100.0% 61.3%
Institutions holding 245 316 483
Change in shares held, QoQ -6.3% +5.9% +5.0%
Institutions buying 175 220 284
Institutions selling 47 64 118
Buyers to sellers 3.72 3.44 2.41

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

CAISHCTEM
CAI 1.00 0.38 0.57
SHC 0.38 1.00 0.44
TEM 0.57 0.44 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, CAI, SHC and TEM?

Tempus AI (TEM) is the largest by market capitalisation: Caris Life Sciences (CAI) $9.52B, Sotera Health (SHC) $5.28B, Tempus AI (TEM) $13.00B.

Which stock is cheaper, CAI, SHC and TEM?

Sotera Health (SHC) trades on the lowest price-to-earnings ratio (Caris Life Sciences (CAI) 90.5x, Sotera Health (SHC) 32.3x, Tempus AI (TEM) -51.1x). On next year's consensus earnings, Sotera Health (SHC) is cheapest (Caris Life Sciences (CAI) 295.1x, Sotera Health (SHC) 20.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Caris Life Sciences (CAI) +85.4%, Sotera Health (SHC) +8.1%, Tempus AI (TEM) +50.4%.

Which company is more profitable?

Sotera Health (SHC) has the highest net margin (Caris Life Sciences (CAI) 10.6%, Sotera Health (SHC) 13.4%, Tempus AI (TEM) -17.8%). On return on invested capital, Caris Life Sciences (CAI) leads (Caris Life Sciences (CAI) 15.6%, Sotera Health (SHC) 9.1%, Tempus AI (TEM) -52.0%).

Which stock has performed better?

Over the past year Sotera Health (SHC) returned the most: Caris Life Sciences (CAI) +4.5%, Sotera Health (SHC) +9.1%, Tempus AI (TEM) -24.7%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Sotera Health (SHC) has been the steadiest (Caris Life Sciences (CAI) 69.6%, Sotera Health (SHC) 28.5%, Tempus AI (TEM) 76.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, CAI, SHC and TEM?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Sotera Health (SHC) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.