BSX vs ISRG vs PEN Stock Comparison

Boston Scientific, Intuitive Surgical and Penumbra Prices as of Oct 27, 2026 Peers: Industry group
BSX Boston Scientific Corp
$45.08 +2.6% 1M -56.0% 1Y
Market cap
$65.33B
P/E
18.0x
Revenue (TTM)
$21.00B
Div. yield
–
Medical Devices Healthcare
2 wins
ISRG Intuitive Surgical Inc
$445.88 +10.0% 1M -19.1% 1Y
Market cap
$154.54B
P/E
52.6x
Revenue (TTM)
$11.58B
Div. yield
–
Medical Devices Healthcare
5 wins
PEN Penumbra Inc
$324.07 +1.6% 1M +30.7% 1Y
Market cap
$12.76B
P/E
79.4x
Revenue (TTM)
$1.50B
Div. yield
–
Medical Devices Healthcare
2 wins

Head to Head

9 decided of 12

Intuitive Surgical leads on 5 of the 12 questions below (Intuitive Surgical 5, Boston Scientific 2, Penumbra 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBSXISRGPENLeader
Larger companyMarket capitalisation $65.33B $154.54B $12.76B ISRG
Cheaper on earningsLower P/E, profitable companies only 18.0x 52.6x 79.4x BSX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 14.4x 38.9x 72.3x BSX
Faster revenue growthRevenue growth, trailing twelve months +13.5% +20.5% +17.6% ISRG
More profitableNet margin, trailing twelve months 17.5% 25.5% 10.7% ISRG
Better return on capitalReturn on invested capital 10.5% — — –
Less leveragedLower net debt / EBITDA 2.2x — — –
Higher dividend yieldTrailing dividend yield — — — –
Better 1-year returnPrice return, last 12 months -56.0% -19.1% +30.7% PEN
Better 5-year returnAnnualised price return, 5 years +0.8%/yr +4.6%/yr +3.1%/yr ISRG
Less volatileAnnualised volatility, 1 year 39.9% 34.6% 26.4% PEN
Higher overall scoreMean of the five percentile scores vs peers 69/100 80/100 74/100 ISRG

Percentile Scorecard

BSXISRGPEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBSXISRGPEN
Valuation 89 #26 of 227 54 #106 of 227 55 #103 of 227
Growth 86 #32 of 219 80 #45 of 219 93 #16 of 219
Profitability 91 #19 of 206 98 #6 of 206 86 #30 of 206
Financial Health 42 #138 of 238 78 #53 of 238 85 #36 of 238
Shareholder Returns 39 #82 of 134 92 #12 of 134 50 #68 of 134
Overall 69 80 74
  • BSX ranked among 247 companies in Medical Devices and Diagnostics
  • ISRG ranked among 247 companies in Medical Devices and Diagnostics
  • PEN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBSXISRGPENSPY
1 month +2.6%+10.0%+1.6% -0.2%
3 months -2.3%+23.2%+1.3% +3.9%
6 months -22.9%-4.4%-0.6% +8.2%
Year to date -52.7%-21.3%+4.2% +12.9%
1 year -56.0%-19.1%+30.7% +12.3%
3 years -9.0%+72.2%+68.1% +87.4%
3 years, per year -3.1%+19.9%+18.9% +23.3%
5 years +4.3%+25.4%+16.6% +67.9%
5 years, per year +0.8%+4.6%+3.1% +10.9%
10 years +109.8%+505.1%+401.7% +261.1%
10 years, per year +7.7%+19.7%+17.5% +13.7%

Risk

MeasureBSXISRGPENSPY
Volatility, 1Y 39.9%34.6%26.4% 12.7%
Downside volatility, 1Y 46.9%37.4%17.7% 12.7%
Beta vs S&P 500, 1Y 0.140.890.06 1.00
Return / volatility, 1Y -1.40-0.551.16 0.97
Max drawdown, 5Y -61.6%-49.9%-59.7% -25.4%
From 52-week high -57.1%-24.8%-9.8% -1.2%
52-week high $104.98$592.85$359.40 $779.14
52-week low $41.57$332.02$225.54 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBSXISRGPEN
P/E now vs peer median 18.0xmedian 29.6x 52.6xmedian 29.6x 79.4xmedian 29.6x
P/S now vs peer median 3.1xmedian 2.9x 13.3xmedian 2.9x 8.5xmedian 2.9x
EV/EBITDA now vs peer median 13.9xmedian 17.4x 36.8xmedian 17.4x 59.2xmedian 17.4x
P/FCF now vs peer median 18.0xmedian 22.3x 43.0xmedian 22.3x 59.1xmedian 22.3x
P/B now vs peer median 2.6xmedian 2.3x 9.6xmedian 2.3x 8.3xmedian 2.3x
PEG now vs peer median 0.29median 1.04 2.05median 1.04 1.04median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBSXISRGPEN
Revenue $21.00B $11.58B $1.50B
Gross profit $14.68B $7.78B $1.02B
Operating income $4.15B $3.28B $187.34M
Net income $3.67B $2.97B $160.59M
Free cash flow $3.63B $3.60B $215.91M
R&D $2.15B $1.49B $92.25M
EPS (diluted) $2.49 $8.41 $4.06
Cash & equivalents $539.00M $2.98B $205.27M
Total debt $12.62B – –
Shares (diluted) 1.47B 351.60M 39.57M
Enterprise value $60.34B $134.96B $10.48B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBSXISRGPEN
P/E 18.0x 52.6x 79.4x
P/FCF 18.0x 43.0x 59.1x
P/Operating cash flow 14.4x 37.8x 45.9x
P/S 3.1x 13.3x 8.5x
P/B 2.6x 9.6x 8.3x
P/Tangible book 3.6x 10.4x 8.4x
EV/EBITDA 13.9x 36.8x 59.2x
EV/EBIT 18.6x 45.8x 64.6x
EV/Revenue 3.7x 13.0x 8.0x
EV/FCF 21.4x 41.8x 56.1x
EV/Operating cash flow 17.1x 36.8x 43.6x
PEG (3Y EPS CAGR) 0.29 2.05 1.04

Growth

14 metrics
MetricBSXISRGPEN
Revenue growth (1Y) 13.5% 20.5% 17.6%
Revenue CAGR (3Y) 16.1% 19.1% 17.1%
Gross profit growth (1Y) 16.3% 21.9% 20.0%
Gross profit CAGR (3Y) 16.4% 19.5% 19.9%
Operating income growth (1Y) 31.9% 16.6% 17.6%
Operating income CAGR (3Y) 31.5% 24.8% 73.0%
Net income growth (1Y) 46.9% 7.5% 8.7%
Net income CAGR (3Y) 59.0% 24.4% 76.7%
EPS growth (1Y) 48.6% 10.8% 7.8%
EPS CAGR (3Y) 61.5% 25.7% 76.1%
Operating cash flow growth (1Y) 5.7% 38.1% 37.9%
Operating cash flow CAGR (3Y) 28.7% 26.4% 146.0%
Free cash flow growth (1Y) 4.0% 58.4% 33.6%
Free cash flow CAGR (3Y) 33.9% 42.0% 650.9%

Profitability

14 metrics
MetricBSXISRGPEN
Gross margin 69.9% 67.2% 67.8%
EBITDA margin 26.5% 35.3% 13.6%
Operating margin 19.8% 28.4% 12.4%
Pretax margin 18.4% 31.3% 13.5%
Net margin 17.5% 25.5% 10.7%
FCF margin 17.3% 31.1% 14.3%
Operating cash flow margin 21.6% 35.3% 18.5%
Return on equity 14.3% 17.3% 10.7%
Return on assets 8.2% 14.8% 8.3%
Return on invested capital 10.5% – –
Return on capital employed 10.8% 18.7% 11.0%
Asset turnover 0.5x 0.6x 0.8x
Cash conversion (OCF / net income) 1.2x 1.4x 1.7x
Stock comp / revenue 1.5% 7.2% 4.0%

Financial Health

11 metrics
MetricBSXISRGPEN
Debt / assets 27.9% – –
Debt / equity 0.5x – –
Net debt / EBITDA 2.2x – –
Debt / FCF 3.5x – –
Liabilities / assets 44.3% 16.7% 22.5%
Equity / assets 55.7% 83.3% 77.5%
Interest coverage 11.4x – –
Current ratio 1.2x 3.3x 5.7x
Quick ratio 0.6x 2.3x 3.6x
Cash ratio 0.1x 1.6x 2.8x
Altman Z-score 3.01 30.55 19.22

Shareholder Returns

7 metrics
MetricBSXISRGPEN
Dividend yield – – –
Net buyback yield -0.3% 2.8% -0.2%
Shareholder yield -0.3% 2.8% -0.2%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBSXISRGPEN
Forward P/E 14.4xFY2026 38.9xFY2026 72.3xFY2026
EPS, next fiscal year $3.12FY2026 $11.47FY2026 $4.48FY2026
EPS growth, next FY +2.0%FY2026 +28.4%FY2026 +16.7%FY2026
EPS growth, the year after +14.7% +4.5% +42.6%
Revenue, next fiscal year $20.67BFY2026 $11.60BFY2026 $1.63BFY2026
Revenue growth, next FY +3.0%FY2026 +15.3%FY2026 +16.3%FY2026
Revenue growth, the year after +1.6% +11.3% +7.5%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBSXISRGPEN
Held by institutions 90.5% 86.2% 86.6%
Institutions holding 1,481 2,235 451
Change in shares held, QoQ -0.7% +4.6% +0.9%
Institutions buying 738 1,070 195
Institutions selling 610 877 182
Buyers to sellers 1.21 1.22 1.07

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BSXISRGPEN
BSX 1.00 0.38 0.29
ISRG 0.38 1.00 0.12
PEN 0.29 0.12 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BSX, ISRG and PEN?

Intuitive Surgical (ISRG) is the largest by market capitalisation: Boston Scientific (BSX) $65.33B, Intuitive Surgical (ISRG) $154.54B, Penumbra (PEN) $12.76B.

Which stock is cheaper, BSX, ISRG and PEN?

Boston Scientific (BSX) trades on the lowest price-to-earnings ratio (Boston Scientific (BSX) 18.0x, Intuitive Surgical (ISRG) 52.6x, Penumbra (PEN) 79.4x). On next year's consensus earnings, Boston Scientific (BSX) is cheapest (Boston Scientific (BSX) 14.4x, Intuitive Surgical (ISRG) 38.9x, Penumbra (PEN) 72.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Intuitive Surgical (ISRG) grew revenue fastest over the trailing twelve months: Boston Scientific (BSX) +13.5%, Intuitive Surgical (ISRG) +20.5%, Penumbra (PEN) +17.6%.

Which company is more profitable?

Intuitive Surgical (ISRG) has the highest net margin (Boston Scientific (BSX) 17.5%, Intuitive Surgical (ISRG) 25.5%, Penumbra (PEN) 10.7%).

Which stock has performed better?

Over the past year Penumbra (PEN) returned the most: Boston Scientific (BSX) -56.0%, Intuitive Surgical (ISRG) -19.1%, Penumbra (PEN) +30.7%. Over five years, Intuitive Surgical (ISRG) compounded fastest (Boston Scientific (BSX) +0.8%/yr, Intuitive Surgical (ISRG) +4.6%/yr, Penumbra (PEN) +3.1%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Penumbra (PEN) has been the steadiest (Boston Scientific (BSX) 39.9%, Intuitive Surgical (ISRG) 34.6%, Penumbra (PEN) 26.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BSX, ISRG and PEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Intuitive Surgical (ISRG) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.