BNTX vs MRNA vs BIIB Stock Comparison

BioNTech SE, Moderna and Biogen Prices as of Oct 29, 2026 Peers: Industry group
BNTX BioNTech SE
$89.13 -9.6% 1M -13.8% 1Y
Market cap
$22.54B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
1 win
MRNA Moderna, Inc.
$222.76 +9.5% 1M +801.9% 1Y
Market cap
$88.88B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins
BIIB Biogen Inc.
$249.65 +9.9% 1M +68.8% 1Y
Market cap
$36.90B
P/E
106.2x
Revenue (TTM)
$10.30B
Div. yield
–
Biotechnology Healthcare
5 wins

Head to Head

9 decided of 12

Biogen leads on 5 of the 12 questions below (Biogen 5, Moderna 3, BioNTech SE 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNTXMRNABIIBLeader
Larger companyMarket capitalisation $22.54B $88.88B $36.90B MRNA
Cheaper on earningsLower P/E, profitable companies only -11.0x -28.1x 106.2x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 19.5x –
Faster revenue growthRevenue growth, trailing twelve months -1.1% -27.6% +2.3% BIIB
More profitableNet margin, trailing twelve months -63.5% -141.4% 3.4% BIIB
Better return on capitalReturn on invested capital -10.7% -43.3% 1.3% BIIB
Less leveragedLower net debt / EBITDA 8.7x 1.5x 4.5x MRNA
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months -13.8% +801.9% +68.8% MRNA
Better 5-year returnAnnualised price return, 5 years -20.4%/yr -8.4%/yr -1.3%/yr BIIB
Less volatileAnnualised volatility, 1 year 46.6% 130.6% 34.3% BIIB
Higher overall scoreMean of the five percentile scores vs peers 65/100 57/100 60/100 BNTX

Percentile Scorecard

BNTXMRNABIIB

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNTXMRNABIIB
Valuation 90 #61 of 624 70 #191 of 624 92 #53 of 624
Growth 15 #512 of 601 19 #485 of 601 26 #444 of 601
Profitability 77 #123 of 541 58 #230 of 541 87 #72 of 541
Financial Health 89 #72 of 647 54 #296 of 647 33 #432 of 647
Shareholder Returns 52 #174 of 359 86 #52 of 359 –
Overall 65 57 60
  • BNTX ranked among 671 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 671 companies in Pharmaceuticals and Biotechnology
  • BIIB ranked among 671 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNTXMRNABIIBSPY
1 month -9.6%+9.5%+9.9% +0.7%
3 months -4.0%+284.6%+20.1% +3.7%
6 months -13.8%+384.9%+31.9% +7.1%
Year to date -6.4%+655.4%+41.9% +12.8%
1 year -13.8%+801.9%+68.8% +11.9%
3 years -4.4%+200.7%+5.2% +85.2%
3 years, per year -1.5%+44.4%+1.7% +22.8%
5 years -68.0%-35.5%-6.4% +67.6%
5 years, per year -20.4%-8.4%-1.3% +10.9%
10 years ——-12.0% +262.0%
10 years, per year ——-1.3% +13.7%

Risk

MeasureBNTXMRNABIIBSPY
Volatility, 1Y 46.6%130.6%34.3% 12.7%
Downside volatility, 1Y 46.8%79.8%32.8% 12.6%
Beta vs S&P 500, 1Y 0.952.150.25 1.00
Return / volatility, 1Y -0.296.142.01 0.94
Max drawdown, 5Y -78.4%-93.9%-64.4% -25.4%
From 52-week high -25.3%-9.4%-1.7% -1.2%
52-week high $119.34$245.81$253.84 $779.14
52-week low $83.89$22.36$147.86 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNTXMRNABIIB
P/E now vs peer median -11.0xmedian 17.8x -28.1xmedian 17.8x 106.2xmedian 17.8x
P/S now vs peer median 7.3xmedian 9.1x 39.9xmedian 9.1x 3.6xmedian 9.1x
EV/EBITDA now vs peer median -6.0xmedian 15.0x -27.4xmedian 15.0x 32.3xmedian 15.0x
P/FCF now vs peer median 21.7xmedian 21.7x -71.4xmedian 21.7x 17.8xmedian 21.7x
P/B now vs peer median 1.1xmedian 2.2x 13.1xmedian 2.2x 2.0xmedian 2.2x
PEG now vs peer median 0.31median 0.35 0.43median 0.35 -2.76median 0.35

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNTXMRNABIIB
Revenue $3.09B $2.23B $10.30B
Gross profit $2.34B $521.00M $7.62B
Operating income -$2.33B -$3.32B $445.10M
Net income -$1.97B -$3.15B $347.50M
Free cash flow $1.04B -$1.24B $2.07B
R&D $2.54B $2.88B $2.15B
EPS (diluted) $-8.13 $-7.92 $2.35
Cash & equivalents $11.13B $1.72B $1.30B
Total debt $102.80M $591.00M $7.29B
Shares (diluted) 241.70M 398.00M 147.80M
Enterprise value -$23.94B $68.24B $26.22B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNTXMRNABIIB
P/E -11.0x -28.1x 106.2x
P/FCF 21.7x -71.4x 17.8x
P/Operating cash flow 28.4x -82.8x 16.4x
P/S 7.3x 39.9x 3.6x
P/B 1.1x 13.1x 2.0x
P/Tangible book 1.1x 13.1x 6.7x
EV/EBITDA -6.0x -27.4x 32.3x
EV/EBIT -4.0x -25.4x 96.4x
EV/Revenue 3.0x 37.9x 4.2x
EV/FCF 8.9x -67.8x 20.7x
EV/Operating cash flow 11.6x -78.6x 19.1x
PEG (3Y EPS CAGR) 0.31 0.43 -2.76

Growth

14 metrics
MetricBNTXMRNABIIB
Revenue growth (1Y) -1.1% -27.6% 2.3%
Revenue CAGR (3Y) -31.0% -40.6% 1.0%
Gross profit growth (1Y) -6.4% -67.8% 0.6%
Gross profit CAGR (3Y) -34.2% -56.0% 0.5%
Operating income growth (1Y) -142.6% -1.4% -76.6%
Operating income CAGR (3Y) -33.8% -103.9% -34.8%
Net income growth (1Y) -417.0% -8.5% -78.4%
Net income CAGR (3Y) -34.6% -66.4% -38.1%
EPS growth (1Y) -393.7% -5.8% -78.5%
EPS CAGR (3Y) -34.9% -65.1% -38.5%
Operating cash flow growth (1Y) 142.8% 60.2% -8.4%
Operating cash flow CAGR (3Y) -56.6% -68.1% 18.2%
Free cash flow growth (1Y) 164.1% 64.4% -10.1%
Free cash flow CAGR (3Y) -53.1% -18.2% 24.9%

Profitability

14 metrics
MetricBNTXMRNABIIB
Gross margin 75.5% 23.4% 74.0%
EBITDA margin -49.7% -138.2% 12.9%
Operating margin -75.2% -149.0% 4.3%
Pretax margin -61.4% -138.6% 4.3%
Net margin -63.5% -141.4% 3.4%
FCF margin 33.6% -55.8% 20.1%
Operating cash flow margin 25.6% -48.2% 21.8%
Return on equity -10.3% -44.5% 1.8%
Return on assets -9.0% -28.1% 1.1%
Return on invested capital -10.7% -43.3% 1.3%
Return on capital employed -9.9% -38.2% 1.6%
Asset turnover 0.1x 0.2x 0.3x
Cash conversion (OCF / net income) -0.4x 0.3x 6.5x
Stock comp / revenue 3.6% 20.7% 2.9%

Financial Health

11 metrics
MetricBNTXMRNABIIB
Debt / assets 0.4% 5.4% 22.7%
Debt / equity 0.0x 0.1x 0.4x
Net debt / EBITDA 8.7x 1.5x 4.5x
Debt / FCF 0.1x -0.5x 3.5x
Liabilities / assets 12.7% 38.3% 41.0%
Equity / assets 87.3% 61.7% 59.0%
Interest coverage -41.1x – –
Current ratio 65.1x 2.3x 1.9x
Quick ratio 50.7x 2.0x 0.9x
Cash ratio 50.0x 2.0x 0.3x
Altman Z-score 6.41 12.91 3.11

Shareholder Returns

7 metrics
MetricBNTXMRNABIIB
Dividend yield – – –
Net buyback yield -2.9% -0.1% –
Shareholder yield -2.9% -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNTXMRNABIIB
Forward P/E – – 19.5xFY2026
EPS, next fiscal year $-6.21FY2026 $-8.02FY2026 $12.81FY2026
EPS growth, next FY – – -16.2%FY2026
EPS growth, the year after – – +36.5%
Revenue, next fiscal year $1.90BFY2026 $2.04BFY2026 $9.96BFY2026
Revenue growth, next FY -43.7%FY2026 +5.1%FY2026 +0.7%FY2026
Revenue growth, the year after +11.9% +26.8% +11.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNTXMRNABIIB
Held by institutions 19.4% 80.2% 96.4%
Institutions holding 282 785 1,037
Change in shares held, QoQ -1.2% +3.4% +6.0%
Institutions buying 136 402 549
Institutions selling 73 239 294
Buyers to sellers 1.86 1.68 1.87

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNTXMRNABIIB
BNTX 1.00 0.59 0.21
MRNA 0.59 1.00 0.22
BIIB 0.21 0.22 1.00

Add a Peer

Largest companies in the same industry

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Frequently Asked Questions

Which is bigger, BNTX, MRNA and BIIB?

Moderna (MRNA) is the largest by market capitalisation: BioNTech SE (BNTX) $22.54B, Moderna (MRNA) $88.88B, Biogen (BIIB) $36.90B.

Which company is growing faster?

Biogen (BIIB) grew revenue fastest over the trailing twelve months: BioNTech SE (BNTX) -1.1%, Moderna (MRNA) -27.6%, Biogen (BIIB) +2.3%.

Which company is more profitable?

Biogen (BIIB) has the highest net margin (BioNTech SE (BNTX) -63.5%, Moderna (MRNA) -141.4%, Biogen (BIIB) 3.4%). On return on invested capital, Biogen (BIIB) leads (BioNTech SE (BNTX) -10.7%, Moderna (MRNA) -43.3%, Biogen (BIIB) 1.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: BioNTech SE (BNTX) -13.8%, Moderna (MRNA) +801.9%, Biogen (BIIB) +68.8%. Over five years, Biogen (BIIB) compounded fastest (BioNTech SE (BNTX) -20.4%/yr, Moderna (MRNA) -8.4%/yr, Biogen (BIIB) -1.3%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Biogen (BIIB) has been the steadiest (BioNTech SE (BNTX) 46.6%, Moderna (MRNA) 130.6%, Biogen (BIIB) 34.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNTX, MRNA and BIIB?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Biogen (BIIB) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.