BNTX vs MRNA vs ARGX Stock Comparison

BioNTech SE, Moderna and Argenx Se Prices as of Oct 27, 2026 Peers: Industry group
BNTX BioNTech SE
$87.06 -11.6% 1M -17.9% 1Y
Market cap
$22.02B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
1 win
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$82.98B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.61B
P/E
28.8x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
5 wins

Head to Head

9 decided of 12

Argenx Se leads on 5 of the 12 questions below (Argenx Se 5, Moderna 3, BioNTech SE 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNTXMRNAARGXLeader
Larger companyMarket capitalisation $22.02B $82.98B $54.61B MRNA
Cheaper on earningsLower P/E, profitable companies only -10.7x -26.3x 28.8x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS — — 28.8x –
Faster revenue growthRevenue growth, trailing twelve months -1.1% -27.6% +61.5% ARGX
More profitableNet margin, trailing twelve months -63.5% -141.4% 32.3% ARGX
Better return on capitalReturn on invested capital -10.7% -43.3% — BNTX
Less leveragedLower net debt / EBITDA 8.7x 1.5x — MRNA
Higher dividend yieldTrailing dividend yield 0.00% — — –
Better 1-year returnPrice return, last 12 months -17.9% +680.1% +6.3% MRNA
Better 5-year returnAnnualised price return, 5 years -21.1%/yr -9.8%/yr +25.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 46.6% 130.8% 36.9% ARGX
Higher overall scoreMean of the five percentile scores vs peers 64/100 57/100 92/100 ARGX

Percentile Scorecard

BNTXMRNAARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNTXMRNAARGX
Valuation 91 #58 of 625 69 #193 of 625 84 #99 of 625
Growth 14 #520 of 602 18 #493 of 602 94 #35 of 602
Profitability 77 #129 of 551 57 #239 of 551 98 #11 of 551
Financial Health 89 #71 of 656 55 #298 of 656 –
Shareholder Returns 51 #179 of 365 85 #57 of 365 –
Overall 64 57 92
  • BNTX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNTXMRNAARGXSPY
1 month -11.6%+4.6%-8.0% -0.2%
3 months -5.8%+272.6%+1.2% +3.9%
6 months -14.7%+341.2%+13.9% +8.2%
Year to date -8.6%+605.2%+4.9% +12.9%
1 year -17.9%+680.1%+6.3% +12.3%
3 years -4.5%+189.2%+91.9% +87.4%
3 years, per year -1.5%+42.5%+24.3% +23.3%
5 years -69.3%-40.2%+214.2% +67.9%
5 years, per year -21.1%-9.8%+25.8% +10.9%

Risk

MeasureBNTXMRNAARGXSPY
Volatility, 1Y 46.6%130.8%36.9% 12.7%
Downside volatility, 1Y 46.5%79.5%34.6% 12.7%
Beta vs S&P 500, 1Y 0.952.150.39 1.00
Return / volatility, 1Y -0.385.200.17 0.97
Max drawdown, 5Y -78.4%-93.9%-38.2% -25.4%
From 52-week high -27.0%-15.4%-16.7% -1.2%
52-week high $119.34$245.81$1,058.90 $779.14
52-week low $83.89$22.36$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNTXMRNAARGX
P/E now vs peer median -10.7xmedian 17.2x -26.3xmedian 17.2x 28.8xmedian 17.2x
P/S now vs peer median 7.1xmedian 9.0x 37.2xmedian 9.0x 9.4xmedian 9.0x
EV/EBITDA now vs peer median -5.7xmedian 16.3x -25.5xmedian 16.3x —median 16.3x
P/FCF now vs peer median 21.2xmedian 18.7x -66.7xmedian 18.7x —median 18.7x
P/B now vs peer median 1.1xmedian 2.2x 12.3xmedian 2.2x —median 2.2x
PEG now vs peer median 0.31median 0.33 0.40median 0.33 0.27median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNTXMRNAARGX
Revenue $3.09B $2.23B $5.82B
Gross profit $2.34B $521.00M $5.24B
Operating income -$2.33B -$3.32B $1.74B
Net income -$1.97B -$3.15B $1.88B
Free cash flow $1.04B -$1.24B –
R&D $2.54B $2.88B $1.80B
EPS (diluted) $-8.13 $-7.92 $28.43
Cash & equivalents $11.13B $1.72B –
Total debt $102.80M $591.00M –
Shares (diluted) 241.70M 398.00M 66.03M
Enterprise value -$24.46B $62.33B $54.61B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNTXMRNAARGX
P/E -10.7x -26.3x 28.8x
P/FCF 21.2x -66.7x –
P/Operating cash flow 27.8x -77.3x –
P/S 7.1x 37.2x 9.4x
P/B 1.1x 12.3x –
P/Tangible book 1.1x 12.3x –
EV/EBITDA -5.7x -25.5x –
EV/EBIT -3.7x -23.6x 31.4x
EV/Revenue 2.8x 35.2x 9.4x
EV/FCF 8.4x -63.0x –
EV/Operating cash flow 11.0x -73.1x –
PEG (3Y EPS CAGR) 0.31 0.40 0.27

Growth

14 metrics
MetricBNTXMRNAARGX
Revenue growth (1Y) -1.1% -27.6% 61.5%
Revenue CAGR (3Y) -31.0% -40.6% 80.5%
Gross profit growth (1Y) -6.4% -67.8% 62.2%
Gross profit CAGR (3Y) -34.2% -56.0% 80.0%
Operating income growth (1Y) -142.6% -1.4% 120.6%
Operating income CAGR (3Y) -33.8% -103.9% 85.1%
Net income growth (1Y) -417.0% -8.5% 22.5%
Net income CAGR (3Y) -34.6% -66.4% 115.5%
EPS growth (1Y) -393.7% -5.8% 20.9%
EPS CAGR (3Y) -34.9% -65.1% 104.8%
Operating cash flow growth (1Y) 142.8% 60.2% –
Operating cash flow CAGR (3Y) -56.6% -68.1% –
Free cash flow growth (1Y) 164.1% 64.4% –
Free cash flow CAGR (3Y) -53.1% -18.2% –

Profitability

14 metrics
MetricBNTXMRNAARGX
Gross margin 75.5% 23.4% 90.0%
EBITDA margin -49.7% -138.2% –
Operating margin -75.2% -149.0% 29.9%
Pretax margin -61.4% -138.6% 32.6%
Net margin -63.5% -141.4% 32.3%
FCF margin 33.6% -55.8% –
Operating cash flow margin 25.6% -48.2% –
Return on equity -10.3% -44.5% –
Return on assets -9.0% -28.1% –
Return on invested capital -10.7% -43.3% –
Return on capital employed -9.9% -38.2% –
Asset turnover 0.1x 0.2x –
Cash conversion (OCF / net income) -0.4x 0.3x –
Stock comp / revenue 3.6% 20.7% –

Financial Health

11 metrics
MetricBNTXMRNAARGX
Debt / assets 0.4% 5.4% –
Debt / equity 0.0x 0.1x –
Net debt / EBITDA 8.7x 1.5x –
Debt / FCF 0.1x -0.5x –
Liabilities / assets 12.7% 38.3% –
Equity / assets 87.3% 61.7% –
Interest coverage -41.1x – 10,120x
Current ratio 65.1x 2.3x –
Quick ratio 50.7x 2.0x –
Cash ratio 50.0x 2.0x –
Altman Z-score 6.31 12.07 –

Shareholder Returns

7 metrics
MetricBNTXMRNAARGX
Dividend yield – – –
Net buyback yield -2.9% -0.1% –
Shareholder yield -2.9% -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNTXMRNAARGX
Forward P/E – – 28.8xFY2026
EPS, next fiscal year $-6.21FY2026 $-8.02FY2026 $30.63FY2026
EPS growth, next FY – – +56.5%FY2026
EPS growth, the year after – – +26.9%
Revenue, next fiscal year $1.90BFY2026 $2.04BFY2026 $6.08BFY2026
Revenue growth, next FY -43.7%FY2026 +5.1%FY2026 +43.1%FY2026
Revenue growth, the year after +11.9% +26.8% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNTXMRNAARGX
Held by institutions 19.4% 80.2% 46.1%
Institutions holding 281 784 504
Change in shares held, QoQ -1.2% +3.4% -2.0%
Institutions buying 136 402 264
Institutions selling 73 238 160
Buyers to sellers 1.86 1.69 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNTXMRNAARGX
BNTX 1.00 0.59 0.23
MRNA 0.59 1.00 0.17
ARGX 0.23 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BNTX, MRNA and ARGX?

Moderna (MRNA) is the largest by market capitalisation: BioNTech SE (BNTX) $22.02B, Moderna (MRNA) $82.98B, Argenx Se (ARGX) $54.61B.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: BioNTech SE (BNTX) -1.1%, Moderna (MRNA) -27.6%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (BioNTech SE (BNTX) -63.5%, Moderna (MRNA) -141.4%, Argenx Se (ARGX) 32.3%). On return on invested capital, BioNTech SE (BNTX) leads (BioNTech SE (BNTX) -10.7%, Moderna (MRNA) -43.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: BioNTech SE (BNTX) -17.9%, Moderna (MRNA) +680.1%, Argenx Se (ARGX) +6.3%. Over five years, Argenx Se (ARGX) compounded fastest (BioNTech SE (BNTX) -21.1%/yr, Moderna (MRNA) -9.8%/yr, Argenx Se (ARGX) +25.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Argenx Se (ARGX) has been the steadiest (BioNTech SE (BNTX) 46.6%, Moderna (MRNA) 130.8%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNTX, MRNA and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.