BNTX vs ARGX vs REGN Stock Comparison

BioNTech SE, Argenx Se and Regeneron Pharmaceuticals Prices as of Oct 27, 2026 Peers: Industry group
BNTX BioNTech SE
$87.06 -11.6% 1M -17.9% 1Y
Market cap
$21.23B
P/E
–
Revenue (TTM)
$3.09B
Div. yield
–
Biotechnology Healthcare
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.54B
P/E
29.1x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
4 wins

Head to Head

11 decided of 12

Regeneron Pharmaceuticals leads on 7 of the 12 questions below (Regeneron Pharmaceuticals 7, Argenx Se 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNTXARGXREGNLeader
Larger companyMarket capitalisation $21.23B $54.54B $83.57B REGN
Cheaper on earningsLower P/E, profitable companies only -10.8x 29.1x 19.3x REGN
Cheaper on forward earningsLower price / next fiscal year consensus EPS — 28.8x 14.3x REGN
Faster revenue growthRevenue growth, trailing twelve months -1.1% +61.5% +9.3% ARGX
More profitableNet margin, trailing twelve months -63.5% 32.3% 27.9% ARGX
Better return on capitalReturn on invested capital -10.7% — 9.6% REGN
Less leveragedLower net debt / EBITDA 8.7x — -1.4x REGN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months -17.9% +6.3% +39.4% REGN
Better 5-year returnAnnualised price return, 5 years -21.1%/yr +25.8%/yr +5.5%/yr ARGX
Less volatileAnnualised volatility, 1 year 46.6% 36.9% 32.8% REGN
Higher overall scoreMean of the five percentile scores vs peers 64/100 92/100 72/100 ARGX

Percentile Scorecard

BNTXARGXREGN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNTXARGXREGN
Valuation 91 #58 of 625 84 #99 of 625 89 #71 of 625
Growth 14 #520 of 602 94 #35 of 602 42 #351 of 602
Profitability 77 #129 of 551 98 #11 of 551 90 #54 of 551
Financial Health 89 #71 of 656 – 74 #172 of 656
Shareholder Returns 51 #179 of 365 – 65 #129 of 365
Overall 64 92 72
  • BNTX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology
  • REGN ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNTXARGXREGNSPY
1 month -11.6%-8.0%+3.6% -0.2%
3 months -5.8%+1.2%+17.4% +3.9%
6 months -14.7%+13.9%+11.5% +8.2%
Year to date -8.6%+4.9%+5.7% +12.9%
1 year -17.9%+6.3%+39.4% +12.3%
3 years -4.5%+91.9%+5.3% +87.4%
3 years, per year -1.5%+24.3%+1.7% +23.3%
5 years -69.3%+214.2%+30.5% +67.9%
5 years, per year -21.1%+25.8%+5.5% +10.9%
10 years ——+123.4% +261.1%
10 years, per year ——+8.4% +13.7%

Risk

MeasureBNTXARGXREGNSPY
Volatility, 1Y 46.6%36.9%32.8% 12.7%
Downside volatility, 1Y 46.5%34.6%30.0% 12.7%
Beta vs S&P 500, 1Y 0.950.390.47 1.00
Return / volatility, 1Y -0.380.171.20 0.97
Max drawdown, 5Y -78.4%-38.2%-59.8% -25.4%
From 52-week high -27.0%-16.7%-4.2% -1.2%
52-week high $119.34$1,058.90$852.03 $779.14
52-week low $83.89$663.93$585.31 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNTXARGXREGN
P/E now vs peer median -10.7xmedian 17.2x 28.8xmedian 17.2x 19.4xmedian 17.2x
P/S now vs peer median 7.1xmedian 9.0x 9.4xmedian 9.0x 5.4xmedian 9.0x
EV/EBITDA now vs peer median -5.7xmedian 16.3x —median 16.3x 17.8xmedian 16.3x
P/FCF now vs peer median 21.2xmedian 18.7x —median 18.7x 22.3xmedian 18.7x
P/B now vs peer median 1.1xmedian 2.2x —median 2.2x 2.6xmedian 2.2x
PEG now vs peer median 0.31median 0.33 0.27median 0.33 7.29median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNTXARGXREGN
Revenue $3.09B $5.82B $15.53B
Gross profit $2.34B $5.24B $13.18B
Operating income -$2.33B $1.74B $3.84B
Net income -$1.97B $1.88B $4.33B
Free cash flow $1.04B – $3.76B
R&D $2.54B $1.80B $6.28B
EPS (diluted) $-8.13 $28.43 $40.84
Cash & equivalents $11.13B – $2.46B
Total debt $102.80M – $1.99B
Shares (diluted) 241.70M 66.03M 106.00M
Enterprise value -$25.25B $54.54B $49.77B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNTXARGXREGN
P/E -10.7x 28.8x 19.4x
P/FCF 21.2x – 22.3x
P/Operating cash flow 27.8x – 17.9x
P/S 7.1x 9.4x 5.4x
P/B 1.1x – 2.6x
P/Tangible book 1.1x – 2.8x
EV/EBITDA -5.7x – 17.8x
EV/EBIT -3.7x 31.4x 20.3x
EV/Revenue 2.8x 9.4x 5.0x
EV/FCF 8.4x – 20.7x
EV/Operating cash flow 11.0x – 16.6x
PEG (3Y EPS CAGR) 0.31 0.27 7.29

Growth

14 metrics
MetricBNTXARGXREGN
Revenue growth (1Y) -1.1% 61.5% 9.3%
Revenue CAGR (3Y) -31.0% 80.5% 7.0%
Gross profit growth (1Y) -6.4% 62.2% 8.4%
Gross profit CAGR (3Y) -34.2% 80.0% 6.4%
Operating income growth (1Y) -142.6% 120.6% 0.1%
Operating income CAGR (3Y) -33.8% 85.1% -3.9%
Net income growth (1Y) -417.0% 22.5% -2.9%
Net income CAGR (3Y) -34.6% 115.5% 0.2%
EPS growth (1Y) -393.7% 20.9% -0.5%
EPS CAGR (3Y) -34.9% 104.8% 2.7%
Operating cash flow growth (1Y) 142.8% – -1.3%
Operating cash flow CAGR (3Y) -56.6% – -0.4%
Free cash flow growth (1Y) 164.1% – -2.4%
Free cash flow CAGR (3Y) -53.1% – -3.3%

Profitability

14 metrics
MetricBNTXARGXREGN
Gross margin 75.5% 90.0% 84.9%
EBITDA margin -49.7% – 28.1%
Operating margin -75.2% 29.9% 24.7%
Pretax margin -61.4% 32.6% 33.3%
Net margin -63.5% 32.3% 27.9%
FCF margin 33.6% – 24.2%
Operating cash flow margin 25.6% – 30.1%
Return on equity -10.3% – 13.7%
Return on assets -9.0% – 10.5%
Return on invested capital -10.7% – 9.6%
Return on capital employed -9.9% – 10.7%
Asset turnover 0.1x – 0.4x
Cash conversion (OCF / net income) -0.4x – 1.1x
Stock comp / revenue 3.6% – 6.4%

Financial Health

11 metrics
MetricBNTXARGXREGN
Debt / assets 0.4% – 4.8%
Debt / equity 0.0x – 0.1x
Net debt / EBITDA 8.7x – -1.4x
Debt / FCF 0.1x – 0.5x
Liabilities / assets 12.7% – 24.0%
Equity / assets 87.3% – 76.0%
Interest coverage -41.1x 10,120x 69.4x
Current ratio 65.1x – 3.3x
Quick ratio 50.7x – 2.6x
Cash ratio 50.0x – 1.4x
Altman Z-score 6.31 – 7.33

Shareholder Returns

7 metrics
MetricBNTXARGXREGN
Dividend yield – – 0.5%
Net buyback yield -2.9% – 3.0%
Shareholder yield -2.9% – 3.5%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNTXARGXREGN
Forward P/E – 28.8xFY2026 14.3xFY2026
EPS, next fiscal year $-6.21FY2026 $30.63FY2026 $57.08FY2026
EPS growth, next FY – +56.5%FY2026 +28.8%FY2026
EPS growth, the year after – +26.9% +15.5%
Revenue, next fiscal year $1.90BFY2026 $6.08BFY2026 $17.05BFY2026
Revenue growth, next FY -43.7%FY2026 +43.1%FY2026 +18.9%FY2026
Revenue growth, the year after +11.9% +22.9% +13.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNTXARGXREGN
Held by institutions 19.4% 46.1% 66.2%
Institutions holding 281 504 1,325
Change in shares held, QoQ -1.2% -2.0% +3.8%
Institutions buying 136 264 604
Institutions selling 73 160 534
Buyers to sellers 1.86 1.65 1.13

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNTXARGXREGN
BNTX 1.00 0.23 0.26
ARGX 0.23 1.00 0.23
REGN 0.26 0.23 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BNTX, ARGX and REGN?

Regeneron Pharmaceuticals (REGN) is the largest by market capitalisation: BioNTech SE (BNTX) $21.23B, Argenx Se (ARGX) $54.54B, Regeneron Pharmaceuticals (REGN) $83.57B.

Which stock is cheaper, BNTX, ARGX and REGN?

Regeneron Pharmaceuticals (REGN) trades on the lowest price-to-earnings ratio (BioNTech SE (BNTX) -10.8x, Argenx Se (ARGX) 29.1x, Regeneron Pharmaceuticals (REGN) 19.3x). On next year's consensus earnings, Regeneron Pharmaceuticals (REGN) is cheapest (Argenx Se (ARGX) 28.8x, Regeneron Pharmaceuticals (REGN) 14.3x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: BioNTech SE (BNTX) -1.1%, Argenx Se (ARGX) +61.5%, Regeneron Pharmaceuticals (REGN) +9.3%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (BioNTech SE (BNTX) -63.5%, Argenx Se (ARGX) 32.3%, Regeneron Pharmaceuticals (REGN) 27.9%). On return on invested capital, Regeneron Pharmaceuticals (REGN) leads (BioNTech SE (BNTX) -10.7%, Regeneron Pharmaceuticals (REGN) 9.6%).

Which stock has performed better?

Over the past year Regeneron Pharmaceuticals (REGN) returned the most: BioNTech SE (BNTX) -17.9%, Argenx Se (ARGX) +6.3%, Regeneron Pharmaceuticals (REGN) +39.4%. Over five years, Argenx Se (ARGX) compounded fastest (BioNTech SE (BNTX) -21.1%/yr, Argenx Se (ARGX) +25.8%/yr, Regeneron Pharmaceuticals (REGN) +5.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Regeneron Pharmaceuticals (REGN) has been the steadiest (BioNTech SE (BNTX) 46.6%, Argenx Se (ARGX) 36.9%, Regeneron Pharmaceuticals (REGN) 32.8%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNTX, ARGX and REGN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Regeneron Pharmaceuticals (REGN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.