BNR vs CSTL vs GH Stock Comparison

Burning Rock Biotech, Castle Biosciences and Guardant Health Prices as of Oct 27, 2026 Peers: Industry group
BNR Burning Rock Biotech Ltd
$11.87 -36.2% 1M +1.5% 1Y
Market cap
$108.24M
P/E
–
Revenue (TTM)
$72.00M
Div. yield
–
Diagnostic Labs Healthcare
1 win
CSTL Castle Biosciences Inc
$34.51 -3.6% 1M +44.0% 1Y
Market cap
$1.12B
P/E
–
Revenue (TTM)
$357.28M
Div. yield
–
Diagnostic Labs Healthcare
2 wins
GH Guardant Health, Inc.
$178.06 +0.5% 1M +151.3% 1Y
Market cap
$24.31B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
5 wins

Head to Head

8 decided of 12

Guardant Health leads on 5 of the 12 questions below (Guardant Health 5, Castle Biosciences 2, Burning Rock Biotech 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNRCSTLGHLeader
Larger companyMarket capitalisation $108.24M $1.12B $24.31B GH
Cheaper on earningsLower P/E, profitable companies only -11.1x -57.9x -53.6x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 3.5x — — –
Faster revenue growthRevenue growth, trailing twelve months -3.9% +3.2% +42.7% GH
More profitableNet margin, trailing twelve months -13.6% -5.4% -38.3% CSTL
Better return on capitalReturn on invested capital -12.3% -6.7% — CSTL
Less leveragedLower net debt / EBITDA — 15.5x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +1.5% +44.0% +151.3% GH
Better 5-year returnAnnualised price return, 5 years -39.3%/yr -11.6%/yr +8.5%/yr GH
Less volatileAnnualised volatility, 1 year 127.8% 58.3% 57.4% GH
Higher overall scoreMean of the five percentile scores vs peers 55/100 50/100 28/100 BNR

Percentile Scorecard

BNRCSTLGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNRCSTLGH
Valuation 39 #57 of 92 47 #49 of 92 18 #76 of 92
Growth 72 #25 of 87 52 #42 of 87 49 #45 of 87
Profitability 28 #62 of 86 39 #53 of 86 7 #80 of 86
Financial Health 82 #18 of 97 92 #9 of 97 52 #47 of 97
Shareholder Returns – 20 #45 of 56 15 #48 of 56
Overall 55 50 28
  • BNR ranked among 102 companies in Healthcare Providers
  • CSTL ranked among 102 companies in Healthcare Providers
  • GH ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNRCSTLGHSPY
1 month -36.2%-3.6%+0.5% -0.2%
3 months +30.6%+44.5%+24.0% +3.9%
6 months -28.7%+39.8%+114.3% +8.2%
Year to date -41.1%-11.3%+74.3% +12.9%
1 year +1.5%+44.0%+151.3% +12.3%
3 years +12.5%+164.2%+613.4% +87.4%
3 years, per year +4.0%+38.3%+92.6% +23.3%
5 years -91.8%-46.0%+50.7% +67.9%
5 years, per year -39.3%-11.6%+8.5% +10.9%

Risk

MeasureBNRCSTLGHSPY
Volatility, 1Y 127.8%58.3%57.4% 12.7%
Downside volatility, 1Y 125.5%61.4%48.7% 12.7%
Beta vs S&P 500, 1Y 1.990.961.03 1.00
Return / volatility, 1Y 0.010.762.64 0.97
Max drawdown, 5Y -98.6%-82.1%-86.7% -25.4%
From 52-week high -71.1%-19.8%-4.9% -1.2%
52-week high $41.06$43.04$187.22 $779.14
52-week low $7.04$18.15$69.58 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNRCSTLGH
P/E now vs peer median -10.8xmedian 24.6x -54.0xmedian 24.6x -52.2xmedian 24.6x
P/S now vs peer median 1.7xmedian 1.6x 2.9xmedian 1.6x 20.1xmedian 1.6x
EV/EBITDA now vs peer median —median 14.6x -48.2xmedian 14.6x -52.7xmedian 14.6x
P/FCF now vs peer median -64.5xmedian 21.6x -2,153xmedian 21.6x -98.8xmedian 21.6x
P/B now vs peer median 1.7xmedian 3.2x 2.2xmedian 3.2x -106.8xmedian 3.2x
PEG now vs peer median -0.19median 0.66 -1.28median 0.66 -5.25median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNRCSTLGH
Revenue $72.00M $357.28M $1.18B
Gross profit $53.66M $276.03M $769.16M
Operating income -$9.36M -$32.11M -$470.26M
Net income -$11.22M -$19.42M -$453.44M
Free cash flow -$1.93M -$489.00K -$240.72M
R&D $19.39M $55.45M $375.79M
EPS (diluted) $-0.92 $-0.64 $-3.41
Cash & equivalents $61.43M $62.12M $1.05B
Total debt $1.09M $10.08M –
Shares (diluted) 10.63M 30.40M 132.87M
Enterprise value -$151.40M $9.27M $20.37B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNRCSTLGH
P/E -10.8x -54.0x -52.2x
P/FCF -64.5x -2,153x -98.8x
P/Operating cash flow -64.5x 24.7x -128.5x
P/S 1.7x 2.9x 20.1x
P/B 1.7x 2.2x -106.8x
P/Tangible book 1.7x 2.2x -95.9x
EV/EBITDA – -48.2x -52.7x
EV/EBIT -6.8x -24.8x -48.4x
EV/Revenue 0.9x 2.2x 19.2x
EV/FCF -32.9x -1,628x -94.5x
EV/Operating cash flow -32.9x 18.7x -122.8x
PEG (3Y EPS CAGR) -0.19 -1.28 -5.25

Growth

14 metrics
MetricBNRCSTLGH
Revenue growth (1Y) -3.9% 3.2% 42.7%
Revenue CAGR (3Y) -4.7% 28.7% 32.4%
Gross profit growth (1Y) -0.7% -1.6% 47.7%
Gross profit CAGR (3Y) -2.7% 29.2% –
Operating income growth (1Y) 54.6% -39.3% -2.1%
Operating income CAGR (3Y) 56.1% 30.8% 4.8%
Net income growth (1Y) 43.6% -105.1% -9.6%
Net income CAGR (3Y) 52.7% 39.8% 3.7%
EPS growth (1Y) 51.7% -99.3% -2.4%
EPS CAGR (3Y) 55.6% 42.3% 9.9%
Operating cash flow growth (1Y) 92.5% -31.8% 22.4%
Operating cash flow CAGR (3Y) 67.4% 45.1% 18.1%
Free cash flow growth (1Y) 86.5% -101.4% 11.4%
Free cash flow CAGR (3Y) 67.4% 78.8% 14.4%

Profitability

14 metrics
MetricBNRCSTLGH
Gross margin 74.5% 77.3% 65.0%
EBITDA margin – -4.6% -36.5%
Operating margin -13.0% -9.0% -39.7%
Pretax margin -13.3% -5.4% -38.4%
Net margin -13.6% -5.4% -38.3%
FCF margin -2.7% -0.1% -20.3%
Operating cash flow margin -2.7% 11.9% -15.7%
Return on equity -15.1% -4.2% –
Return on assets -10.0% -3.5% -23.7%
Return on invested capital -12.3% -6.7% –
Return on capital employed -11.7% -6.4% -29.9%
Asset turnover 0.6x 0.6x 0.6x
Cash conversion (OCF / net income) 0.2x -2.2x 0.4x
Stock comp / revenue – 12.6% 16.2%

Financial Health

11 metrics
MetricBNRCSTLGH
Debt / assets 0.2% 1.8% –
Debt / equity 0.0x 0.0x –
Net debt / EBITDA – 15.5x –
Debt / FCF -0.1x -20.6x –
Liabilities / assets 33.8% 16.2% 111.7%
Equity / assets 66.2% 83.8% -11.7%
Interest coverage – -85.6x -97.6x
Current ratio 3.1x 6.0x 4.0x
Quick ratio 2.8x 5.6x 3.5x
Cash ratio 1.9x 4.7x 3.1x
Altman Z-score -4.91 7.39 4.77

Shareholder Returns

7 metrics
MetricBNRCSTLGH
Dividend yield – – –
Net buyback yield – -0.5% -1.7%
Shareholder yield – -0.5% -1.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNRCSTLGH
Forward P/E 3.5xFY2026 – –
EPS, next fiscal year $3.38FY2026 $-1.31FY2026 $-3.33FY2026
Revenue, next fiscal year $171.24MFY2026 $385.85MFY2026 $1.42BFY2026
Revenue growth, next FY +121.9%FY2026 +12.1%FY2026 +44.5%FY2026
Revenue growth, the year after – +2.3% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNRCSTLGH
Held by institutions 16.5% 89.6% 100.0%
Institutions holding 17 177 594
Change in shares held, QoQ +1.5% -1.0% -2.6%
Institutions buying 9 104 353
Institutions selling 4 55 180
Buyers to sellers 2.25 1.89 1.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNRCSTLGH
BNR 1.00 0.06 0.02
CSTL 0.06 1.00 0.45
GH 0.02 0.45 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BNR, CSTL and GH?

Guardant Health (GH) is the largest by market capitalisation: Burning Rock Biotech (BNR) $108.24M, Castle Biosciences (CSTL) $1.12B, Guardant Health (GH) $24.31B.

Which company is growing faster?

Guardant Health (GH) grew revenue fastest over the trailing twelve months: Burning Rock Biotech (BNR) -3.9%, Castle Biosciences (CSTL) +3.2%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Castle Biosciences (CSTL) has the highest net margin (Burning Rock Biotech (BNR) -13.6%, Castle Biosciences (CSTL) -5.4%, Guardant Health (GH) -38.3%). On return on invested capital, Castle Biosciences (CSTL) leads (Burning Rock Biotech (BNR) -12.3%, Castle Biosciences (CSTL) -6.7%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Burning Rock Biotech (BNR) +1.5%, Castle Biosciences (CSTL) +44.0%, Guardant Health (GH) +151.3%. Over five years, Guardant Health (GH) compounded fastest (Burning Rock Biotech (BNR) -39.3%/yr, Castle Biosciences (CSTL) -11.6%/yr, Guardant Health (GH) +8.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Guardant Health (GH) has been the steadiest (Burning Rock Biotech (BNR) 127.8%, Castle Biosciences (CSTL) 58.3%, Guardant Health (GH) 57.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNR, CSTL and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Guardant Health (GH) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.