BNR vs CAI vs GRAL Stock Comparison

Burning Rock Biotech, Caris Life Sciences and Grail Prices as of Oct 29, 2026 Peers: Industry group
BNR Burning Rock Biotech Ltd
$11.05 -41.7% 1M -11.7% 1Y
Market cap
$116.23M
P/E
–
Revenue (TTM)
$72.00M
Div. yield
–
Diagnostic Labs Healthcare
1 win
CAI Caris Life Sciences, Inc.
$36.14 +14.5% 1M +22.8% 1Y
Market cap
$10.21B
P/E
97.2x
Revenue (TTM)
$989.61M
Div. yield
–
Diagnostic Labs Healthcare
6 wins
GRAL GRAIL, Inc.
$158.92 +16.4% 1M +86.5% 1Y
Market cap
$7.10B
P/E
–
Revenue (TTM)
$157.21M
Div. yield
–
Diagnostic Labs Healthcare
1 win

Head to Head

8 decided of 12

Caris Life Sciences leads on 6 of the 12 questions below (Caris Life Sciences 6, Burning Rock Biotech 1, Grail 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBNRCAIGRALLeader
Larger companyMarket capitalisation $116.23M $10.21B $7.10B CAI
Cheaper on earningsLower P/E, profitable companies only -10.0x 97.2x -17.5x –
Cheaper on forward earningsLower price / next fiscal year consensus EPS 3.3x 328.5x — BNR
Faster revenue growthRevenue growth, trailing twelve months -3.9% +85.4% +17.1% CAI
More profitableNet margin, trailing twelve months -13.6% 10.6% -249.1% CAI
Better return on capitalReturn on invested capital -12.3% 15.6% — CAI
Less leveragedLower net debt / EBITDA — -2.2x — –
Higher dividend yieldTrailing dividend yield — 0.00% — –
Better 1-year returnPrice return, last 12 months -11.7% +22.8% +86.5% GRAL
Better 5-year returnAnnualised price return, 5 years -39.9%/yr — — –
Less volatileAnnualised volatility, 1 year 128.1% 69.7% 111.4% CAI
Higher overall scoreMean of the five percentile scores vs peers 56/100 71/100 43/100 CAI

Percentile Scorecard

BNRCAIGRAL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBNRCAIGRAL
Valuation 40 #56 of 92 25 #69 of 92 8 #85 of 92
Growth 72 #25 of 87 99 #2 of 87 59 #36 of 87
Profitability 29 #61 of 86 89 #10 of 86 6 #81 of 86
Financial Health 83 #17 of 97 81 #19 of 97 99 #2 of 97
Shareholder Returns – 61 #22 of 55 –
Overall 56 71 43
  • BNR ranked among 102 companies in Healthcare Providers
  • CAI ranked among 102 companies in Healthcare Providers
  • GRAL ranked among 102 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBNRCAIGRALSPY
1 month -41.7%+14.5%+16.4% +0.7%
3 months +24.9%+124.6%+123.4% +3.7%
6 months -35.0%+90.2%+191.7% +7.1%
Year to date -45.2%+34.0%+85.7% +12.8%
1 year -11.7%+22.8%+86.5% +11.9%
3 years +10.5%—— +85.2%
3 years, per year +3.4%—— +22.8%
5 years -92.2%—— +67.6%
5 years, per year -39.9%—— +10.9%

Risk

MeasureBNRCAIGRALSPY
Volatility, 1Y 128.1%69.7%111.4% 12.7%
Downside volatility, 1Y 125.8%69.4%126.6% 12.6%
Beta vs S&P 500, 1Y 2.021.392.69 1.00
Return / volatility, 1Y -0.090.330.78 0.94
Max drawdown, 5Y -98.6%-63.0%-62.9% -25.4%
From 52-week high -73.1%0.0%0.0% -1.2%
52-week high $41.06$36.14$158.92 $779.14
52-week low $7.04$14.55$43.03 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBNRCAIGRAL
P/E now vs peer median -10.0xmedian 26.0x 97.2xmedian 26.0x -17.5xmedian 26.0x
P/S now vs peer median 1.6xmedian 1.6x 10.3xmedian 1.6x 45.2xmedian 1.6x
EV/EBITDA now vs peer median —median 15.4x 54.5xmedian 15.4x -15.4xmedian 15.4x
P/FCF now vs peer median -60.1xmedian 21.5x 82.4xmedian 21.5x -24.0xmedian 21.5x
P/B now vs peer median 1.6xmedian 3.2x 17.3xmedian 3.2x 2.8xmedian 3.2x
PEG now vs peer median -0.18median 0.87 —median 0.87 —median 0.87

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBNRCAIGRAL
Revenue $72.00M $989.61M $157.21M
Gross profit $53.66M $689.36M $75.51M
Operating income -$9.36M $153.26M -$559.25M
Net income -$11.22M $105.14M -$391.59M
Free cash flow -$1.93M $123.96M -$296.16M
R&D $19.39M $117.14M $190.72M
EPS (diluted) $-0.92 $0.37 $-9.08
Cash & equivalents $61.43M $690.92M $55.65M
Total debt $1.09M $393.15M –
Shares (diluted) 10.63M 282.89M 43.11M
Enterprise value -$143.42M $7.04B $3.97B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBNRCAIGRAL
P/E -10.0x 97.2x -17.5x
P/FCF -60.1x 82.4x -24.0x
P/Operating cash flow -60.1x 60.6x -24.1x
P/S 1.6x 10.3x 45.2x
P/B 1.6x 17.3x 2.8x
P/Tangible book 1.6x 17.3x 9.3x
EV/EBITDA – 54.5x -15.4x
EV/EBIT -5.9x 64.0x -11.2x
EV/Revenue 0.8x 9.9x 39.7x
EV/FCF -28.5x 79.2x -21.1x
EV/Operating cash flow -28.5x 58.2x -21.2x
PEG (3Y EPS CAGR) -0.18 – –

Growth

14 metrics
MetricBNRCAIGRAL
Revenue growth (1Y) -3.9% 85.4% 17.1%
Revenue CAGR (3Y) -4.7% – –
Gross profit growth (1Y) -0.7% 141.2% 30.2%
Gross profit CAGR (3Y) -2.7% – –
Operating income growth (1Y) 54.6% 188.2% 11.6%
Operating income CAGR (3Y) 56.1% – –
Net income growth (1Y) 43.6% 137.7% 11.6%
Net income CAGR (3Y) 52.7% – –
EPS growth (1Y) 51.7% 103.0% 26.6%
EPS CAGR (3Y) 55.6% – –
Operating cash flow growth (1Y) 92.5% 227.3% 20.3%
Operating cash flow CAGR (3Y) 67.4% – –
Free cash flow growth (1Y) 86.5% 188.2% 20.3%
Free cash flow CAGR (3Y) 67.4% – –

Profitability

14 metrics
MetricBNRCAIGRAL
Gross margin 74.5% 69.7% 48.0%
EBITDA margin – 18.2% -257.6%
Operating margin -13.0% 15.5% -355.7%
Pretax margin -13.3% 10.6% -336.8%
Net margin -13.6% 10.6% -249.1%
FCF margin -2.7% 12.5% -188.4%
Operating cash flow margin -2.7% 17.0% -187.5%
Return on equity -15.1% 17.7% -15.5%
Return on assets -10.0% 8.8% -13.9%
Return on invested capital -12.3% 15.6% –
Return on capital employed -11.7% 15.3% -20.4%
Asset turnover 0.6x 0.8x 0.1x
Cash conversion (OCF / net income) 0.2x 1.6x 0.8x
Stock comp / revenue – 6.6% 40.9%

Financial Health

11 metrics
MetricBNRCAIGRAL
Debt / assets 0.2% 32.0% –
Debt / equity 0.0x 0.7x –
Net debt / EBITDA – -2.2x –
Debt / FCF -0.1x 3.2x –
Liabilities / assets 33.8% 51.9% 10.6%
Equity / assets 66.2% 48.1% 89.4%
Interest coverage – 3.3x –
Current ratio 3.1x 5.5x 10.9x
Quick ratio 2.8x 4.8x 10.6x
Cash ratio 1.9x 4.1x 10.3x
Altman Z-score -5.05 8.76 8.78

Shareholder Returns

7 metrics
MetricBNRCAIGRAL
Dividend yield – – –
Net buyback yield – 0.1% –
Shareholder yield – 0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBNRCAIGRAL
Forward P/E 3.3xFY2026 328.5xFY2026 –
EPS, next fiscal year $3.38FY2026 $0.11FY2026 $-9.05FY2026
EPS growth, the year after – +236.4% –
Revenue, next fiscal year $171.24MFY2026 $1.06BFY2026 $169.78MFY2026
Revenue growth, next FY +121.9%FY2026 +30.1%FY2026 +15.4%FY2026
Revenue growth, the year after – +21.6% +38.2%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBNRCAIGRAL
Held by institutions 16.5% 52.0% 85.4%
Institutions holding 17 246 373
Change in shares held, QoQ +1.5% -6.3% +8.4%
Institutions buying 9 175 183
Institutions selling 4 47 100
Buyers to sellers 2.25 3.72 1.83

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BNRCAIGRAL
BNR 1.00 0.10 0.19
CAI 0.10 1.00 0.33
GRAL 0.19 0.33 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BNR, CAI and GRAL?

Caris Life Sciences (CAI) is the largest by market capitalisation: Burning Rock Biotech (BNR) $116.23M, Caris Life Sciences (CAI) $10.21B, Grail (GRAL) $7.10B.

Which company is growing faster?

Caris Life Sciences (CAI) grew revenue fastest over the trailing twelve months: Burning Rock Biotech (BNR) -3.9%, Caris Life Sciences (CAI) +85.4%, Grail (GRAL) +17.1%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (Burning Rock Biotech (BNR) -13.6%, Caris Life Sciences (CAI) 10.6%, Grail (GRAL) -249.1%). On return on invested capital, Caris Life Sciences (CAI) leads (Burning Rock Biotech (BNR) -12.3%, Caris Life Sciences (CAI) 15.6%).

Which stock has performed better?

Over the past year Grail (GRAL) returned the most: Burning Rock Biotech (BNR) -11.7%, Caris Life Sciences (CAI) +22.8%, Grail (GRAL) +86.5%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Caris Life Sciences (CAI) has been the steadiest (Burning Rock Biotech (BNR) 128.1%, Caris Life Sciences (CAI) 69.7%, Grail (GRAL) 111.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BNR, CAI and GRAL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.