BLLN vs CAI vs GH Stock Comparison

BillionToOne, Caris Life Sciences and Guardant Health Prices as of Oct 26, 2026 Peers: Industry group
BLLN BillionToOne, Inc.
$111.46 -9.4% 1M
Market cap
$5.29B
P/E
176.0x
Revenue (TTM)
$397.41M
Div. yield
–
Diagnostic Labs Healthcare
3 wins
GH Guardant Health, Inc.
$173.25 -2.3% 1M +140.1% 1Y
Market cap
$23.68B
P/E
–
Revenue (TTM)
$1.18B
Div. yield
–
Diagnostic Labs Healthcare
3 wins

Head to Head

10 decided of 12

Caris Life Sciences leads on 4 of the 12 questions below (Caris Life Sciences 4, Guardant Health 3, BillionToOne 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBLLNCAIGHLeader
Larger companyMarket capitalisation $5.29B $9.52B $23.68B GH
Cheaper on earningsLower P/E, profitable companies only 176.0x 90.5x -52.2x CAI
Cheaper on forward earningsLower price / next fiscal year consensus EPS 146.7x 295.1x — BLLN
Faster revenue growthRevenue growth, trailing twelve months +90.1% +85.4% +42.7% BLLN
More profitableNet margin, trailing twelve months 7.6% 10.6% -38.3% CAI
Better return on capitalReturn on invested capital 7.0% 15.6% — CAI
Less leveragedLower net debt / EBITDA -9.1x -2.2x — BLLN
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months — +4.5% +140.1% GH
Better 5-year returnAnnualised price return, 5 years — — +9.1%/yr –
Less volatileAnnualised volatility, 1 year 94.7% 69.6% 57.4% GH
Higher overall scoreMean of the five percentile scores vs peers 56/100 69/100 28/100 CAI

Percentile Scorecard

BLLNCAIGH

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBLLNCAIGH
Valuation 20 #75 of 93 23 #72 of 93 17 #77 of 93
Growth 100 #1 of 88 99 #2 of 88 48 #46 of 88
Profitability 59 #36 of 87 87 #12 of 87 7 #81 of 87
Financial Health 96 #5 of 100 82 #19 of 100 51 #50 of 100
Shareholder Returns 7 #52 of 56 53 #27 of 56 15 #48 of 56
Overall 56 69 28
  • BLLN ranked among 103 companies in Healthcare Providers
  • CAI ranked among 103 companies in Healthcare Providers
  • GH ranked among 103 companies in Healthcare Providers

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBLLNCAIGHSPY
1 month -9.4%+1.5%-2.3% -0.8%
3 months -12.9%+107.7%+19.1% +3.5%
6 months +36.3%+62.9%+95.8% +7.0%
Year to date +36.2%+20.3%+69.6% +12.2%
1 year —+4.5%+140.1% +13.0%
3 years ——+594.1% +86.3%
3 years, per year ——+90.8% +23.1%
5 years ——+54.3% +68.6%
5 years, per year ——+9.1% +11.0%

Risk

MeasureBLLNCAIGHSPY
Volatility, 1Y 94.7%69.6%57.4% 12.7%
Downside volatility, 1Y 107.8%69.3%48.7% 12.7%
Beta vs S&P 500, 1Y 1.661.381.02 1.00
Return / volatility, 1Y —0.062.44 1.02
Max drawdown, 5Y -50.8%-63.0%-86.7% -25.4%
From 52-week high -25.7%0.0%-7.5% -1.8%
52-week high $149.97$32.46$187.22 $779.14
52-week low $64.03$14.55$69.58 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBLLNCAIGH
P/E now vs peer median 172.0xmedian 25.1x 87.3xmedian 25.1x -50.8xmedian 25.1x
P/S now vs peer median 13.1xmedian 1.6x 9.3xmedian 1.6x 19.6xmedian 1.6x
EV/EBITDA now vs peer median 94.8xmedian 14.5x 48.7xmedian 14.5x -51.2xmedian 14.5x
P/FCF now vs peer median 157.3xmedian 22.4x 74.0xmedian 22.4x -96.2xmedian 22.4x
P/B now vs peer median 9.7xmedian 3.1x 15.5xmedian 3.1x -103.9xmedian 3.1x
PEG now vs peer median —median 0.66 —median 0.66 -5.11median 0.66

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBLLNCAIGH
Revenue $397.41M $989.61M $1.18B
Gross profit $283.22M $689.36M $769.16M
Operating income $43.30M $153.26M -$470.26M
Net income $37.71M $105.14M -$453.44M
Free cash flow $33.18M $123.96M -$240.72M
R&D $59.21M $117.14M $375.79M
EPS (diluted) $0.55 $0.37 $-3.41
Cash & equivalents $548.63M $690.92M $1.05B
Total debt $91.03M $393.15M –
Shares (diluted) 54.46M 282.89M 132.87M
Enterprise value $3.51B $6.34B $19.74B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBLLNCAIGH
P/E 172.0x 87.3x -50.8x
P/FCF 157.3x 74.0x -96.2x
P/Operating cash flow 115.1x 54.4x -125.0x
P/S 13.1x 9.3x 19.6x
P/B 9.7x 15.5x -103.9x
P/Tangible book 9.7x 15.5x -93.3x
EV/EBITDA 94.8x 48.7x -51.2x
EV/EBIT 110.0x 57.2x -47.0x
EV/Revenue 12.0x 8.9x 18.7x
EV/FCF 143.5x 70.8x -91.8x
EV/Operating cash flow 105.0x 52.0x -119.3x
PEG (3Y EPS CAGR) – – -5.11

Growth

14 metrics
MetricBLLNCAIGH
Revenue growth (1Y) 90.1% 85.4% 42.7%
Revenue CAGR (3Y) – – 32.4%
Gross profit growth (1Y) 122.4% 141.2% 47.7%
Gross profit CAGR (3Y) – – –
Operating income growth (1Y) 253.2% 188.2% -2.1%
Operating income CAGR (3Y) – – 4.8%
Net income growth (1Y) 223.2% 137.7% -9.6%
Net income CAGR (3Y) – – 3.7%
EPS growth (1Y) 118.7% 103.0% -2.4%
EPS CAGR (3Y) – – 9.9%
Operating cash flow growth (1Y) – 227.3% 22.4%
Operating cash flow CAGR (3Y) – – 18.1%
Free cash flow growth (1Y) – 188.2% 11.4%
Free cash flow CAGR (3Y) – – 14.4%

Profitability

14 metrics
MetricBLLNCAIGH
Gross margin 71.3% 69.7% 65.0%
EBITDA margin 12.6% 18.2% -36.5%
Operating margin 10.9% 15.5% -39.7%
Pretax margin 9.5% 10.6% -38.4%
Net margin 7.6% 10.6% -38.3%
FCF margin 8.3% 12.5% -20.3%
Operating cash flow margin 11.4% 17.0% -15.7%
Return on equity 7.2% 17.7% –
Return on assets 5.3% 8.8% -23.7%
Return on invested capital 7.0% 15.6% –
Return on capital employed 6.6% 15.3% -29.9%
Asset turnover 0.6x 0.8x 0.6x
Cash conversion (OCF / net income) 1.2x 1.6x 0.4x
Stock comp / revenue 6.4% 6.6% 16.2%

Financial Health

11 metrics
MetricBLLNCAIGH
Debt / assets 12.5% 32.0% –
Debt / equity 0.2x 0.7x –
Net debt / EBITDA -9.1x -2.2x –
Debt / FCF 2.7x 3.2x –
Liabilities / assets 26.4% 51.9% 111.7%
Equity / assets 73.6% 48.1% -11.7%
Interest coverage 1,056x 3.3x -97.6x
Current ratio 11.7x 5.5x 4.0x
Quick ratio 11.2x 4.8x 3.5x
Cash ratio 9.8x 4.1x 3.1x
Altman Z-score 17.48 7.79 4.59

Shareholder Returns

7 metrics
MetricBLLNCAIGH
Dividend yield – – –
Net buyback yield -5.8% 0.1% -1.7%
Shareholder yield -5.8% 0.1% -1.7%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBLLNCAIGH
Forward P/E 146.7xFY2026 295.1xFY2026 –
EPS, next fiscal year $0.76FY2026 $0.11FY2026 $-3.33FY2026
EPS growth, next FY +442.9%FY2026 – –
EPS growth, the year after +22.4% +236.4% –
Revenue, next fiscal year $481.76MFY2026 $1.06BFY2026 $1.42BFY2026
Revenue growth, next FY +57.9%FY2026 +30.1%FY2026 +44.5%FY2026
Revenue growth, the year after +27.1% +21.6% +27.0%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBLLNCAIGH
Held by institutions 32.6% 52.0% 100.0%
Institutions holding 155 245 594
Change in shares held, QoQ +34.7% -6.3% -2.6%
Institutions buying 127 175 353
Institutions selling 13 47 180
Buyers to sellers 9.77 3.72 1.96

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BLLNCAIGH
BLLN 1.00 0.10 0.30
CAI 0.10 1.00 0.41
GH 0.30 0.41 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BLLN, CAI and GH?

Guardant Health (GH) is the largest by market capitalisation: BillionToOne (BLLN) $5.29B, Caris Life Sciences (CAI) $9.52B, Guardant Health (GH) $23.68B.

Which stock is cheaper, BLLN, CAI and GH?

Caris Life Sciences (CAI) trades on the lowest price-to-earnings ratio (BillionToOne (BLLN) 176.0x, Caris Life Sciences (CAI) 90.5x, Guardant Health (GH) -52.2x). On next year's consensus earnings, BillionToOne (BLLN) is cheapest (BillionToOne (BLLN) 146.7x, Caris Life Sciences (CAI) 295.1x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

BillionToOne (BLLN) grew revenue fastest over the trailing twelve months: BillionToOne (BLLN) +90.1%, Caris Life Sciences (CAI) +85.4%, Guardant Health (GH) +42.7%.

Which company is more profitable?

Caris Life Sciences (CAI) has the highest net margin (BillionToOne (BLLN) 7.6%, Caris Life Sciences (CAI) 10.6%, Guardant Health (GH) -38.3%). On return on invested capital, Caris Life Sciences (CAI) leads (BillionToOne (BLLN) 7.0%, Caris Life Sciences (CAI) 15.6%).

Which stock has performed better?

Over the past year Guardant Health (GH) returned the most: Caris Life Sciences (CAI) +4.5%, Guardant Health (GH) +140.1%. Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Guardant Health (GH) has been the steadiest (BillionToOne (BLLN) 94.7%, Caris Life Sciences (CAI) 69.6%, Guardant Health (GH) 57.4%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BLLN, CAI and GH?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Caris Life Sciences (CAI) leads on 4. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.