BIO vs ILMN vs RGEN Stock Comparison

Bio-Rad Laboratories, Illumina and Repligen Prices as of Oct 27, 2026 Peers: Industry group
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ILMN Illumina, Inc.
$279.47 +3.5% 1M +178.5% 1Y
Market cap
$43.74B
P/E
53.0x
Revenue (TTM)
$4.49B
Div. yield
–
Life Sciences Tools Healthcare
6 wins
RGEN Repligen Corp
$175.80 -7.3% 1M +9.1% 1Y
Market cap
$10.45B
P/E
–
Revenue (TTM)
$805.61M
Div. yield
–
Life Sciences Tools Healthcare
1 win

Head to Head

10 decided of 12

Illumina leads on 6 of the 12 questions below (Illumina 6, Bio-Rad Laboratories 3, Repligen 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIOILMNRGENLeader
Larger companyMarket capitalisation $10.29B $43.74B $10.45B ILMN
Cheaper on earningsLower P/E, profitable companies only 46.2x 53.0x -885.6x BIO
Cheaper on forward earningsLower price / next fiscal year consensus EPS 38.3x 56.0x 90.6x BIO
Faster revenue growthRevenue growth, trailing twelve months +1.4% +4.9% +13.8% RGEN
More profitableNet margin, trailing twelve months 8.6% 18.4% — ILMN
Better return on capitalReturn on invested capital 0.4% 15.1% — ILMN
Less leveragedLower net debt / EBITDA — 0.7x — –
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +13.3% +178.5% +9.1% ILMN
Better 5-year returnAnnualised price return, 5 years -13.6%/yr -7.0%/yr -9.5%/yr ILMN
Less volatileAnnualised volatility, 1 year 37.0% 50.4% 46.3% BIO
Higher overall scoreMean of the five percentile scores vs peers 63/100 66/100 56/100 ILMN

Percentile Scorecard

BIOILMNRGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIOILMNRGEN
Valuation 78 #51 of 227 51 #111 of 227 43 #129 of 227
Growth 20 #176 of 219 45 #120 of 219 31 #152 of 219
Profitability 71 #61 of 206 97 #8 of 206 68 #66 of 206
Financial Health 68 #77 of 238 51 #117 of 238 83 #41 of 238
Shareholder Returns 80 #28 of 134 84 #23 of 134 –
Overall 63 66 56
  • BIO ranked among 247 companies in Medical Devices and Diagnostics
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • RGEN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIOILMNRGENSPY
1 month +0.0%+3.5%-7.3% -0.2%
3 months +15.2%+44.8%+21.0% +3.9%
6 months +36.4%+120.2%+49.7% +8.2%
Year to date +25.7%+113.1%+7.3% +12.9%
1 year +13.3%+178.5%+9.1% +12.3%
3 years +40.7%+163.0%+47.0% +87.4%
3 years, per year +12.1%+38.1%+13.7% +23.3%
5 years -51.7%-30.5%-39.4% +67.9%
5 years, per year -13.6%-7.0%-9.5% +10.9%
10 years +141.8%+106.3%+513.8% +261.1%
10 years, per year +9.2%+7.5%+19.9% +13.7%

Risk

MeasureBIOILMNRGENSPY
Volatility, 1Y 37.0%50.4%46.3% 12.7%
Downside volatility, 1Y 35.8%39.1%46.8% 12.7%
Beta vs S&P 500, 1Y 0.760.821.21 1.00
Return / volatility, 1Y 0.363.540.20 0.97
Max drawdown, 5Y -72.7%-82.9%-66.2% -25.4%
From 52-week high -2.4%-4.8%-9.6% -1.2%
52-week high $390.34$293.69$194.57 $779.14
52-week low $241.71$95.03$102.87 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIOILMNRGEN
P/E now vs peer median 45.8xmedian 29.6x 51.2xmedian 29.6x -840.2xmedian 29.6x
P/S now vs peer median 3.9xmedian 2.9x 9.4xmedian 2.9x 12.3xmedian 2.9x
EV/EBITDA now vs peer median —median 17.4x 37.3xmedian 17.4x —median 17.4x
P/FCF now vs peer median 28.8xmedian 22.3x 45.3xmedian 22.3x 98.1xmedian 22.3x
P/B now vs peer median 1.4xmedian 2.3x 14.9xmedian 2.3x 4.7xmedian 2.3x
PEG now vs peer median 1.24median 1.04 1.70median 1.04 29.56median 1.04

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIOILMNRGEN
Revenue $2.59B $4.49B $805.61M
Gross profit $1.34B $2.98B –
Operating income $53.10M $882.00M $18.24M
Net income $222.40M $825.00M $26.59M
Free cash flow $353.10M $931.00M –
R&D $265.70M $960.00M $56.43M
EPS (diluted) $8.29 $5.39 $-0.21
Cash & equivalents $517.00M $1.04B $726.96M
Total debt $1.20B $1.99B –
Shares (diluted) 26.81M 153.00M 56.64M
Enterprise value $4.14B $38.51B $10.45B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIOILMNRGEN
P/E 45.8x 51.2x -840.2x
P/FCF 28.8x 45.3x 98.1x
P/Operating cash flow 20.7x 38.5x 76.4x
P/S 3.9x 9.4x 12.3x
P/B 1.4x 14.9x 4.7x
P/Tangible book 1.5x 17.4x 5.6x
EV/EBITDA – 37.3x –
EV/EBIT 184.0x 48.8x –
EV/Revenue 3.8x 9.6x 12.3x
EV/FCF 27.7x 46.2x –
EV/Operating cash flow 19.8x 39.3x 76.4x
PEG (3Y EPS CAGR) 1.24 1.70 29.56

Growth

14 metrics
MetricBIOILMNRGEN
Revenue growth (1Y) 1.4% 4.9% 13.8%
Revenue CAGR (3Y) -2.2% -1.0% 7.3%
Gross profit growth (1Y) -0.4% 4.6% –
Gross profit CAGR (3Y) -3.5% 2.9% –
Operating income growth (1Y) -76.3% -31.8% 2,185%
Operating income CAGR (3Y) -47.4% 28.3% -40.5%
Net income growth (1Y) -30.3% -34.4% 1,430%
Net income CAGR (3Y) 36.1% 30.0% -35.9%
EPS growth (1Y) -29.3% -32.7% -777.9%
EPS CAGR (3Y) 36.9% 30.1% -28.4%
Operating cash flow growth (1Y) -7.8% -5.1% -0.8%
Operating cash flow CAGR (3Y) 19.8% 38.1% -4.0%
Free cash flow growth (1Y) -4.8% -9.7% –
Free cash flow CAGR (3Y) 31.9% 105.0% –

Profitability

14 metrics
MetricBIOILMNRGEN
Gross margin 51.9% 66.4% –
EBITDA margin – 25.7% –
Operating margin 2.1% 19.6% –
Pretax margin 13.5% 22.6% –
Net margin 8.6% 18.4% –
FCF margin 13.6% 20.7% –
Operating cash flow margin 19.0% 24.4% 16.1%
Return on equity 3.2% 29.9% 1.3%
Return on assets 2.2% 12.5% 0.9%
Return on invested capital 0.4% 15.1% –
Return on capital employed 0.6% 17.5% –
Asset turnover 0.3x 0.7x 0.3x
Cash conversion (OCF / net income) 2.2x 1.3x 4.9x
Stock comp / revenue – 5.9% 4.2%

Financial Health

11 metrics
MetricBIOILMNRGEN
Debt / assets 11.7% 29.9% –
Debt / equity 0.2x 0.7x –
Net debt / EBITDA – 0.7x –
Debt / FCF 3.4x 2.1x –
Liabilities / assets 30.0% 57.3% 28.5%
Equity / assets 70.0% 42.7% 71.5%
Interest coverage 1.1x 8.9x –
Current ratio 3.1x 1.8x 9.9x
Quick ratio 2.1x 1.2x –
Cash ratio 1.7x 0.7x –
Altman Z-score 3.59 7.97 –

Shareholder Returns

7 metrics
MetricBIOILMNRGEN
Dividend yield – – –
Net buyback yield 1.2% 1.2% –
Shareholder yield 1.2% 1.2% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIOILMNRGEN
Forward P/E 38.3xFY2026 56.0xFY2026 90.6xFY2026
EPS, next fiscal year $9.95FY2026 $4.99FY2026 $1.94FY2026
EPS growth, next FY +0.3%FY2026 +3.1%FY2026 +13.5%FY2026
EPS growth, the year after -0.2% +25.7% +29.4%
Revenue, next fiscal year $2.69BFY2026 $4.52BFY2026 $773.94MFY2026
Revenue growth, next FY +4.2%FY2026 +4.1%FY2026 +4.8%FY2026
Revenue growth, the year after -6.3% +12.0% +35.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIOILMNRGEN
Held by institutions 89.5% 100.0% 100.0%
Institutions holding 403 933 482
Change in shares held, QoQ -2.9% +0.0% +1.2%
Institutions buying 177 463 272
Institutions selling 155 330 141
Buyers to sellers 1.14 1.40 1.93

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIOILMNRGEN
BIO 1.00 0.33 0.53
ILMN 0.33 1.00 0.41
RGEN 0.53 0.41 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BIO, ILMN and RGEN?

Illumina (ILMN) is the largest by market capitalisation: Bio-Rad Laboratories (BIO) $10.29B, Illumina (ILMN) $43.74B, Repligen (RGEN) $10.45B.

Which stock is cheaper, BIO, ILMN and RGEN?

Bio-Rad Laboratories (BIO) trades on the lowest price-to-earnings ratio (Bio-Rad Laboratories (BIO) 46.2x, Illumina (ILMN) 53.0x, Repligen (RGEN) -885.6x). On next year's consensus earnings, Bio-Rad Laboratories (BIO) is cheapest (Bio-Rad Laboratories (BIO) 38.3x, Illumina (ILMN) 56.0x, Repligen (RGEN) 90.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Repligen (RGEN) grew revenue fastest over the trailing twelve months: Bio-Rad Laboratories (BIO) +1.4%, Illumina (ILMN) +4.9%, Repligen (RGEN) +13.8%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Bio-Rad Laboratories (BIO) 8.6%, Illumina (ILMN) 18.4%). On return on invested capital, Illumina (ILMN) leads (Bio-Rad Laboratories (BIO) 0.4%, Illumina (ILMN) 15.1%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Bio-Rad Laboratories (BIO) +13.3%, Illumina (ILMN) +178.5%, Repligen (RGEN) +9.1%. Over five years, Illumina (ILMN) compounded fastest (Bio-Rad Laboratories (BIO) -13.6%/yr, Illumina (ILMN) -7.0%/yr, Repligen (RGEN) -9.5%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Bio-Rad Laboratories (BIO) has been the steadiest (Bio-Rad Laboratories (BIO) 37.0%, Illumina (ILMN) 50.4%, Repligen (RGEN) 46.3%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIO, ILMN and RGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Illumina (ILMN) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.