BIO vs ILMN vs QGEN Stock Comparison

Bio-Rad Laboratories, Illumina and Qiagen Prices as of Nov 2, 2026 Peers: Industry group
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ILMN Illumina, Inc.
$226.58 -17.0% 1M +83.4% 1Y
Market cap
$34.21B
P/E
38.2x
Revenue (TTM)
$4.54B
Div. yield
–
Life Sciences Tools Healthcare
7 wins
QGEN Qiagen N.V.
$50.33 +12.5% 1M +2.1% 1Y
Market cap
$10.92B
P/E
26.7x
Revenue (TTM)
$2.10B
Div. yield
5.25%
Life Sciences Tools Healthcare
4 wins

Head to Head

11 decided of 12

Illumina leads on 7 of the 12 questions below (Illumina 7, Qiagen 4). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIOILMNQGENLeader
Larger companyMarket capitalisation $9.79B $34.21B $10.92B ILMN
Cheaper on earningsLower P/E, profitable companies only 44.0x 38.2x 26.7x QGEN
Cheaper on forward earningsLower price / next fiscal year consensus EPS 36.8x 45.4x 21.4x QGEN
Faster revenue growthRevenue growth, trailing twelve months +1.4% +5.8% +3.0% ILMN
More profitableNet margin, trailing twelve months 8.6% 19.7% 19.5% ILMN
Better return on capitalReturn on invested capital 0.4% 16.6% 7.9% ILMN
Less leveragedLower net debt / EBITDA — 0.4x 1.3x ILMN
Higher dividend yieldTrailing dividend yield — — 5.25% –
Better 1-year returnPrice return, last 12 months +14.6% +83.4% +2.1% ILMN
Better 5-year returnAnnualised price return, 5 years -14.0%/yr -11.1%/yr -4.0%/yr QGEN
Less volatileAnnualised volatility, 1 year 36.4% 49.9% 35.6% QGEN
Higher overall scoreMean of the five percentile scores vs peers 65/100 75/100 71/100 ILMN

Percentile Scorecard

BIOILMNQGEN

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIOILMNQGEN
Valuation 79 #48 of 227 59 #94 of 227 74 #60 of 227
Growth 21 #174 of 220 73 #60 of 220 29 #156 of 220
Profitability 71 #61 of 209 99 #4 of 209 92 #17 of 209
Financial Health 70 #74 of 240 60 #96 of 240 63 #89 of 240
Shareholder Returns 83 #24 of 138 82 #26 of 138 94 #9 of 138
Overall 65 75 71
  • BIO ranked among 247 companies in Medical Devices and Diagnostics
  • ILMN ranked among 247 companies in Medical Devices and Diagnostics
  • QGEN ranked among 247 companies in Medical Devices and Diagnostics

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIOILMNQGENSPY
1 month -0.8%-17.0%+12.5% -2.3%
3 months +9.4%+14.3%+18.9% -0.7%
6 months +42.0%+62.6%+48.2% +4.8%
Year to date +20.9%+72.8%+6.3% +10.3%
1 year +14.6%+83.4%+2.1% +10.3%
3 years +27.2%+99.2%+15.0% +73.0%
3 years, per year +8.4%+25.8%+4.8% +20.1%
5 years -53.0%-44.5%-18.5% +61.9%
5 years, per year -14.0%-11.1%-4.0% +10.1%
10 years +121.1%+71.7%+81.4% +258.6%
10 years, per year +8.3%+5.6%+6.1% +13.6%

Risk

MeasureBIOILMNQGENSPY
Volatility, 1Y 36.4%49.9%35.6% 12.8%
Downside volatility, 1Y 35.1%49.1%30.3% 12.8%
Beta vs S&P 500, 1Y 0.761.060.45 1.00
Return / volatility, 1Y 0.401.670.06 0.80
Max drawdown, 5Y -72.4%-82.9%-48.2% -25.4%
From 52-week high -6.2%-22.9%-9.6% -3.5%
52-week high $390.34$293.69$55.66 $779.14
52-week low $241.71$114.44$32.63 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIOILMNQGEN
P/E now vs peer median 44.0xmedian 28.4x 38.2xmedian 28.4x 26.7xmedian 28.4x
P/S now vs peer median 3.8xmedian 3.0x 7.5xmedian 3.0x 5.2xmedian 3.0x
EV/EBITDA now vs peer median —median 18.0x 28.0xmedian 18.0x 18.1xmedian 18.0x
P/FCF now vs peer median 27.7xmedian 25.0x 32.4xmedian 25.0x 11.0xmedian 25.0x
P/B now vs peer median 1.4xmedian 2.3x 10.9xmedian 2.3x 3.3xmedian 2.3x
PEG now vs peer median 1.19median 0.93 0.93median 0.93 6.54median 0.93

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIOILMNQGEN
Revenue $2.59B $4.54B $2.10B
Gross profit $1.34B $3.08B $1.31B
Operating income $53.10M $960.00M $445.43M
Net income $222.40M $895.00M $409.32M
Free cash flow $353.10M $1.06B $991.33M
R&D $265.70M $975.00M $194.67M
EPS (diluted) $8.29 $5.85 $1.87
Cash & equivalents $517.00M $1.29B $768.50M
Total debt $1.20B $1.79B $1.64B
Shares (diluted) 26.81M 153.00M 218.88M
Enterprise value $3.65B $28.92B $6.69B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIOILMNQGEN
P/E 44.0x 38.2x 26.7x
P/FCF 27.7x 32.4x 11.0x
P/Operating cash flow 19.9x 27.8x 16.7x
P/S 3.8x 7.5x 5.2x
P/B 1.4x 10.9x 3.3x
P/Tangible book 1.4x 12.4x 3.6x
EV/EBITDA – 28.0x 18.1x
EV/EBIT 176.6x 36.1x 26.4x
EV/Revenue 3.6x 7.6x 5.6x
EV/FCF 26.6x 32.8x 11.9x
EV/Operating cash flow 19.0x 28.2x 18.0x
PEG (3Y EPS CAGR) 1.19 0.93 6.54

Growth

14 metrics
MetricBIOILMNQGEN
Revenue growth (1Y) 1.4% 5.8% 3.0%
Revenue CAGR (3Y) -2.2% -0.7% 2.0%
Gross profit growth (1Y) -0.4% 8.5% 1.7%
Gross profit CAGR (3Y) -3.5% 4.4% 1.3%
Operating income growth (1Y) -76.3% 23.1% -4.9%
Operating income CAGR (3Y) -47.4% 30.0% 3.3%
Net income growth (1Y) -30.3% 27.5% 143.9%
Net income CAGR (3Y) 36.1% 40.9% 6.7%
EPS growth (1Y) -29.3% 28.3% 6.6%
EPS CAGR (3Y) 36.9% 41.3% 4.1%
Operating cash flow growth (1Y) -7.8% 9.6% -3.0%
Operating cash flow CAGR (3Y) 19.8% 47.5% 8.0%
Free cash flow growth (1Y) -4.8% 5.7% 2.3%
Free cash flow CAGR (3Y) 31.9% 126.5% 10.5%

Profitability

14 metrics
MetricBIOILMNQGEN
Gross margin 51.9% 67.9% 62.2%
EBITDA margin – 27.3% 31.0%
Operating margin 2.1% 21.2% 21.2%
Pretax margin 13.5% 23.3% 22.0%
Net margin 8.6% 19.7% 19.5%
FCF margin 13.6% 23.3% 47.2%
Operating cash flow margin 19.0% 27.1% 31.2%
Return on equity 3.2% 29.9% 12.2%
Return on assets 2.2% 13.3% 7.0%
Return on invested capital 0.4% 16.6% 7.9%
Return on capital employed 0.6% 17.2% 8.5%
Asset turnover 0.3x 0.7x 0.4x
Cash conversion (OCF / net income) 2.2x 1.4x 1.6x
Stock comp / revenue – 5.9% 2.1%

Financial Health

11 metrics
MetricBIOILMNQGEN
Debt / assets 11.7% 26.3% 27.9%
Debt / equity 0.2x 0.6x 0.5x
Net debt / EBITDA – 0.4x 1.3x
Debt / FCF 3.4x 1.7x 1.7x
Liabilities / assets 30.0% 53.8% 43.0%
Equity / assets 70.0% 46.2% 57.0%
Interest coverage 1.1x 9.8x 11.3x
Current ratio 3.1x 2.6x 2.8x
Quick ratio 2.1x 1.8x 2.0x
Cash ratio 1.7x 1.2x 1.4x
Altman Z-score 3.51 7.10 4.08

Shareholder Returns

7 metrics
MetricBIOILMNQGEN
Dividend yield – – 5.2%
Net buyback yield 1.2% 1.1% 0.6%
Shareholder yield 1.2% 1.1% 5.8%
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIOILMNQGEN
Forward P/E 36.8xFY2026 45.4xFY2026 21.4xFY2026
EPS, next fiscal year $9.95FY2026 $4.99FY2026 $2.35FY2026
EPS growth, next FY +0.3%FY2026 +3.1%FY2026 -1.3%FY2026
EPS growth, the year after -0.2% +25.7% +17.4%
Revenue, next fiscal year $2.69BFY2026 $4.52BFY2026 $2.25BFY2026
Revenue growth, next FY +4.2%FY2026 +4.1%FY2026 +7.8%FY2026
Revenue growth, the year after -6.3% +12.0% -2.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIOILMNQGEN
Held by institutions 89.5% 100.0% 67.3%
Institutions holding 405 935 338
Change in shares held, QoQ -2.9% +0.0% +16.5%
Institutions buying 177 464 216
Institutions selling 157 331 86
Buyers to sellers 1.13 1.40 2.51

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIOILMNQGEN
BIO 1.00 0.33 0.41
ILMN 0.33 1.00 0.38
QGEN 0.41 0.38 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BIO, ILMN and QGEN?

Illumina (ILMN) is the largest by market capitalisation: Bio-Rad Laboratories (BIO) $9.79B, Illumina (ILMN) $34.21B, Qiagen (QGEN) $10.92B.

Which stock is cheaper, BIO, ILMN and QGEN?

Qiagen (QGEN) trades on the lowest price-to-earnings ratio (Bio-Rad Laboratories (BIO) 44.0x, Illumina (ILMN) 38.2x, Qiagen (QGEN) 26.7x). On next year's consensus earnings, Qiagen (QGEN) is cheapest (Bio-Rad Laboratories (BIO) 36.8x, Illumina (ILMN) 45.4x, Qiagen (QGEN) 21.4x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Illumina (ILMN) grew revenue fastest over the trailing twelve months: Bio-Rad Laboratories (BIO) +1.4%, Illumina (ILMN) +5.8%, Qiagen (QGEN) +3.0%.

Which company is more profitable?

Illumina (ILMN) has the highest net margin (Bio-Rad Laboratories (BIO) 8.6%, Illumina (ILMN) 19.7%, Qiagen (QGEN) 19.5%). On return on invested capital, Illumina (ILMN) leads (Bio-Rad Laboratories (BIO) 0.4%, Illumina (ILMN) 16.6%, Qiagen (QGEN) 7.9%).

Which stock has performed better?

Over the past year Illumina (ILMN) returned the most: Bio-Rad Laboratories (BIO) +14.6%, Illumina (ILMN) +83.4%, Qiagen (QGEN) +2.1%. Over five years, Qiagen (QGEN) compounded fastest (Bio-Rad Laboratories (BIO) -14.0%/yr, Illumina (ILMN) -11.1%/yr, Qiagen (QGEN) -4.0%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Qiagen (QGEN) 5.25%. Bio-Rad Laboratories (BIO) and Illumina (ILMN) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Qiagen (QGEN) has been the steadiest (Bio-Rad Laboratories (BIO) 36.4%, Illumina (ILMN) 49.9%, Qiagen (QGEN) 35.6%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIO, ILMN and QGEN?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Illumina (ILMN) leads on 7. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.