BIIB vs MRNA vs ARGX Stock Comparison

Biogen, Moderna and Argenx Se Prices as of Oct 27, 2026 Peers: Industry group
BIIB Biogen Inc.
$252.73 +11.0% 1M +68.0% 1Y
Market cap
$36.25B
P/E
43.4x
Revenue (TTM)
$10.03B
Div. yield
–
Biotechnology Healthcare
3 wins
MRNA Moderna, Inc.
$207.97 +4.6% 1M +680.1% 1Y
Market cap
$85.10B
P/E
–
Revenue (TTM)
$2.23B
Div. yield
–
Biotechnology Healthcare
3 wins
ARGX Argenx Se
$882.48 -8.0% 1M +6.3% 1Y
Market cap
$54.62B
P/E
29.1x
Revenue (TTM)
$5.82B
Div. yield
–
Biotechnology Healthcare
5 wins

Head to Head

11 decided of 12

Argenx Se leads on 5 of the 12 questions below (Argenx Se 5, Moderna 3, Biogen 3). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIIBMRNAARGXLeader
Larger companyMarket capitalisation $36.25B $85.10B $54.62B MRNA
Cheaper on earningsLower P/E, profitable companies only 43.4x -27.0x 29.1x ARGX
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.7x — 28.8x BIIB
Faster revenue growthRevenue growth, trailing twelve months +0.3% -27.6% +61.5% ARGX
More profitableNet margin, trailing twelve months 8.3% -141.4% 32.3% ARGX
Better return on capitalReturn on invested capital 3.3% -43.3% — BIIB
Less leveragedLower net debt / EBITDA 3.2x 1.5x — MRNA
Higher dividend yieldTrailing dividend yield 0.00% 0.00% 0.00% –
Better 1-year returnPrice return, last 12 months +68.0% +680.1% +6.3% MRNA
Better 5-year returnAnnualised price return, 5 years -0.9%/yr -9.8%/yr +25.8%/yr ARGX
Less volatileAnnualised volatility, 1 year 34.0% 130.8% 36.9% BIIB
Higher overall scoreMean of the five percentile scores vs peers 63/100 57/100 92/100 ARGX

Percentile Scorecard

BIIBMRNAARGX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIIBMRNAARGX
Valuation 92 #52 of 625 69 #193 of 625 84 #99 of 625
Growth 35 #392 of 602 18 #493 of 602 94 #35 of 602
Profitability 89 #64 of 551 57 #239 of 551 98 #11 of 551
Financial Health 35 #425 of 656 55 #298 of 656 –
Shareholder Returns – 85 #57 of 365 –
Overall 63 57 92
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MRNA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • ARGX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIIBMRNAARGXSPY
1 month +11.0%+4.6%-8.0% -0.2%
3 months +22.9%+272.6%+1.2% +3.9%
6 months +37.8%+341.2%+13.9% +8.2%
Year to date +43.6%+605.2%+4.9% +12.9%
1 year +68.0%+680.1%+6.3% +12.3%
3 years +7.8%+189.2%+91.9% +87.4%
3 years, per year +2.5%+42.5%+24.3% +23.3%
5 years -4.6%-40.2%+214.2% +67.9%
5 years, per year -0.9%-9.8%+25.8% +10.9%
10 years -13.1%—— +261.1%
10 years, per year -1.4%—— +13.7%

Risk

MeasureBIIBMRNAARGXSPY
Volatility, 1Y 34.0%130.8%36.9% 12.7%
Downside volatility, 1Y 32.3%79.5%34.6% 12.7%
Beta vs S&P 500, 1Y 0.262.150.39 1.00
Return / volatility, 1Y 2.005.200.17 0.97
Max drawdown, 5Y -64.4%-93.9%-38.2% -25.4%
From 52-week high -0.4%-15.4%-16.7% -1.2%
52-week high $253.84$245.81$1,058.90 $779.14
52-week low $147.86$22.36$663.93 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIIBMRNAARGX
P/E now vs peer median 44.7xmedian 17.2x -26.3xmedian 17.2x 28.8xmedian 17.2x
P/S now vs peer median 3.7xmedian 9.0x 37.2xmedian 9.0x 9.4xmedian 9.0x
EV/EBITDA now vs peer median 23.4xmedian 16.3x -25.5xmedian 16.3x —median 16.3x
P/FCF now vs peer median 13.8xmedian 18.7x -66.7xmedian 18.7x —median 18.7x
P/B now vs peer median 2.0xmedian 2.2x 12.3xmedian 2.2x —median 2.2x
PEG now vs peer median -1.37median 0.33 0.40median 0.33 0.27median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIIBMRNAARGX
Revenue $10.03B $2.23B $5.82B
Gross profit $7.42B $521.00M $5.24B
Operating income $1.01B -$3.32B $1.74B
Net income $834.60M -$3.15B $1.88B
Free cash flow $2.70B -$1.24B –
R&D $2.01B $2.88B $1.80B
EPS (diluted) $5.61 $-7.92 $28.43
Cash & equivalents $1.29B $1.72B –
Total debt $7.29B $591.00M –
Shares (diluted) 148.70M 398.00M 66.03M
Enterprise value $22.91B $64.46B $54.62B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIIBMRNAARGX
P/E 44.7x -26.3x 28.8x
P/FCF 13.8x -66.7x –
P/Operating cash flow 13.0x -77.3x –
P/S 3.7x 37.2x 9.4x
P/B 2.0x 12.3x –
P/Tangible book 7.0x 12.3x –
EV/EBITDA 23.4x -25.5x –
EV/EBIT 42.9x -23.6x 31.4x
EV/Revenue 4.3x 35.2x 9.4x
EV/FCF 16.1x -63.0x –
EV/Operating cash flow 15.1x -73.1x –
PEG (3Y EPS CAGR) -1.37 0.40 0.27

Growth

14 metrics
MetricBIIBMRNAARGX
Revenue growth (1Y) 0.3% -27.6% 61.5%
Revenue CAGR (3Y) 0.2% -40.6% 80.5%
Gross profit growth (1Y) -1.6% -67.8% 62.2%
Gross profit CAGR (3Y) -1.1% -56.0% 80.0%
Operating income growth (1Y) -43.7% -1.4% 120.6%
Operating income CAGR (3Y) -31.3% -103.9% 85.1%
Net income growth (1Y) -45.5% -8.5% 22.5%
Net income CAGR (3Y) -32.1% -66.4% 115.5%
EPS growth (1Y) -46.2% -5.8% 20.9%
EPS CAGR (3Y) -32.6% -65.1% 104.8%
Operating cash flow growth (1Y) 36.0% 60.2% –
Operating cash flow CAGR (3Y) 26.3% -68.1% –
Free cash flow growth (1Y) 36.3% 64.4% –
Free cash flow CAGR (3Y) 33.0% -18.2% –

Profitability

14 metrics
MetricBIIBMRNAARGX
Gross margin 74.0% 23.4% 90.0%
EBITDA margin 18.5% -138.2% –
Operating margin 10.1% -149.0% 29.9%
Pretax margin 10.1% -138.6% 32.6%
Net margin 8.3% -141.4% 32.3%
FCF margin 26.9% -55.8% –
Operating cash flow margin 28.7% -48.2% –
Return on equity 4.5% -44.5% –
Return on assets 2.7% -28.1% –
Return on invested capital 3.3% -43.3% –
Return on capital employed 3.8% -38.2% –
Asset turnover 0.3x 0.2x –
Cash conversion (OCF / net income) 3.4x 0.3x –
Stock comp / revenue 3.0% 20.7% –

Financial Health

11 metrics
MetricBIIBMRNAARGX
Debt / assets 22.7% 5.4% –
Debt / equity 0.4x 0.1x –
Net debt / EBITDA 3.2x 1.5x –
Debt / FCF 2.7x -0.5x –
Liabilities / assets 41.3% 38.3% –
Equity / assets 58.7% 61.7% –
Interest coverage – – 10,120x
Current ratio 1.9x 2.3x –
Quick ratio 1.1x 2.0x –
Cash ratio 0.3x 2.0x –
Altman Z-score 3.15 12.07 –

Shareholder Returns

7 metrics
MetricBIIBMRNAARGX
Dividend yield – – –
Net buyback yield – -0.1% –
Shareholder yield – -0.1% –
Payout ratio (earnings) – – –
Payout ratio (FCF) – – –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIIBMRNAARGX
Forward P/E 19.7xFY2026 – 28.8xFY2026
EPS, next fiscal year $12.81FY2026 $-8.02FY2026 $30.63FY2026
EPS growth, next FY -16.2%FY2026 – +56.5%FY2026
EPS growth, the year after +36.5% – +26.9%
Revenue, next fiscal year $9.96BFY2026 $2.04BFY2026 $6.08BFY2026
Revenue growth, next FY +0.7%FY2026 +5.1%FY2026 +43.1%FY2026
Revenue growth, the year after +11.9% +26.8% +22.9%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIIBMRNAARGX
Held by institutions 96.4% 80.2% 46.1%
Institutions holding 1,036 784 504
Change in shares held, QoQ +6.0% +3.4% -2.0%
Institutions buying 548 402 264
Institutions selling 294 238 160
Buyers to sellers 1.86 1.69 1.65

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIIBMRNAARGX
BIIB 1.00 0.22 0.21
MRNA 0.22 1.00 0.17
ARGX 0.21 0.17 1.00

Add a Peer

Largest companies in the same industry

Related Comparisons

Frequently Asked Questions

Which is bigger, BIIB, MRNA and ARGX?

Moderna (MRNA) is the largest by market capitalisation: Biogen (BIIB) $36.25B, Moderna (MRNA) $85.10B, Argenx Se (ARGX) $54.62B.

Which stock is cheaper, BIIB, MRNA and ARGX?

Argenx Se (ARGX) trades on the lowest price-to-earnings ratio (Biogen (BIIB) 43.4x, Moderna (MRNA) -27.0x, Argenx Se (ARGX) 29.1x). On next year's consensus earnings, Biogen (BIIB) is cheapest (Biogen (BIIB) 19.7x, Argenx Se (ARGX) 28.8x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Argenx Se (ARGX) grew revenue fastest over the trailing twelve months: Biogen (BIIB) +0.3%, Moderna (MRNA) -27.6%, Argenx Se (ARGX) +61.5%.

Which company is more profitable?

Argenx Se (ARGX) has the highest net margin (Biogen (BIIB) 8.3%, Moderna (MRNA) -141.4%, Argenx Se (ARGX) 32.3%). On return on invested capital, Biogen (BIIB) leads (Biogen (BIIB) 3.3%, Moderna (MRNA) -43.3%).

Which stock has performed better?

Over the past year Moderna (MRNA) returned the most: Biogen (BIIB) +68.0%, Moderna (MRNA) +680.1%, Argenx Se (ARGX) +6.3%. Over five years, Argenx Se (ARGX) compounded fastest (Biogen (BIIB) -0.9%/yr, Moderna (MRNA) -9.8%/yr, Argenx Se (ARGX) +25.8%/yr). Returns are price only, before dividends.

Which stock is riskier?

By one-year price volatility, Biogen (BIIB) has been the steadiest (Biogen (BIIB) 34.0%, Moderna (MRNA) 130.8%, Argenx Se (ARGX) 36.9%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIIB, MRNA and ARGX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Argenx Se (ARGX) leads on 5. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.