BIIB vs KMDA vs VRTX Stock Comparison

Biogen, Kamada and Vertex Pharmaceuticals Prices as of Oct 27, 2026 Peers: Industry group
BIIB Biogen Inc.
$252.73 +11.0% 1M +68.0% 1Y
Market cap
$37.34B
P/E
44.7x
Revenue (TTM)
$10.03B
Div. yield
–
Biotechnology Healthcare
1 win
KMDA Kamada Ltd
$8.05 -7.7% 1M +14.5% 1Y
Market cap
$464.37M
P/E
21.0x
Revenue (TTM)
$191.85M
Div. yield
5.22%
Biotechnology Healthcare
6 wins

Head to Head

11 decided of 12

Kamada leads on 6 of the 12 questions below (Kamada 6, Vertex Pharmaceuticals 4, Biogen 1). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIIBKMDAVRTXLeader
Larger companyMarket capitalisation $37.34B $464.37M $132.00B VRTX
Cheaper on earningsLower P/E, profitable companies only 44.7x 21.0x 30.0x KMDA
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.7x 16.1x 28.6x KMDA
Faster revenue growthRevenue growth, trailing twelve months +0.3% +13.2% +10.2% KMDA
More profitableNet margin, trailing twelve months 8.3% 11.5% 35.0% VRTX
Better return on capitalReturn on invested capital 3.3% 10.2% — KMDA
Less leveragedLower net debt / EBITDA 3.2x -1.5x — KMDA
Higher dividend yieldTrailing dividend yield — 5.22% — –
Better 1-year returnPrice return, last 12 months +68.0% +14.5% +24.0% BIIB
Better 5-year returnAnnualised price return, 5 years -0.9%/yr +7.0%/yr +23.4%/yr VRTX
Less volatileAnnualised volatility, 1 year 34.0% 34.7% 29.0% VRTX
Higher overall scoreMean of the five percentile scores vs peers 63/100 84/100 76/100 KMDA

Percentile Scorecard

BIIBKMDAVRTX

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIIBKMDAVRTX
Valuation 92 #52 of 625 97 #22 of 625 81 #121 of 625
Growth 35 #392 of 602 71 #177 of 602 60 #241 of 602
Profitability 89 #64 of 551 88 #70 of 551 95 #30 of 551
Financial Health 35 #425 of 656 74 #169 of 656 53 #307 of 656
Shareholder Returns – 90 #38 of 365 93 #28 of 365
Overall 63 84 76
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • KMDA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • VRTX ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIIBKMDAVRTXSPY
1 month +11.0%-7.7%-1.0% -0.2%
3 months +22.9%+14.0%+6.2% +3.9%
6 months +37.8%-1.2%+21.1% +8.2%
Year to date +43.6%+14.0%+14.9% +12.9%
1 year +68.0%+14.5%+24.0% +12.3%
3 years +7.8%+94.4%+46.7% +87.4%
3 years, per year +2.5%+24.8%+13.6% +23.3%
5 years -4.6%+40.2%+186.3% +67.9%
5 years, per year -0.9%+7.0%+23.4% +10.9%
10 years -13.1%+34.2%+587.0% +261.1%
10 years, per year -1.4%+3.0%+21.3% +13.7%

Risk

MeasureBIIBKMDAVRTXSPY
Volatility, 1Y 34.0%34.7%29.0% 12.7%
Downside volatility, 1Y 32.3%33.2%25.8% 12.7%
Beta vs S&P 500, 1Y 0.261.010.49 1.00
Return / volatility, 1Y 2.000.420.83 0.97
Max drawdown, 5Y -64.4%-44.4%-29.1% -25.4%
From 52-week high -0.4%-13.5%-6.6% -1.2%
52-week high $253.84$9.31$557.96 $779.14
52-week low $147.86$6.62$409.47 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIIBKMDAVRTX
P/E now vs peer median 44.7xmedian 17.2x 21.0xmedian 17.2x 30.0xmedian 17.2x
P/S now vs peer median 3.7xmedian 9.0x 2.4xmedian 9.0x 10.5xmedian 9.0x
EV/EBITDA now vs peer median 23.4xmedian 16.3x 9.3xmedian 16.3x 24.8xmedian 16.3x
P/FCF now vs peer median 13.8xmedian 18.7x 17.6xmedian 18.7x 34.8xmedian 18.7x
P/B now vs peer median 2.0xmedian 2.2x 1.7xmedian 2.2x 6.5xmedian 2.2x
PEG now vs peer median -1.37median 0.33 0.30median 0.33 2.96median 0.33

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIIBKMDAVRTX
Revenue $10.03B $191.85M $12.59B
Gross profit $7.42B $78.31M $10.82B
Operating income $1.01B $27.83M $4.78B
Net income $834.60M $22.25M $4.41B
Free cash flow $2.70B $26.32M $3.80B
R&D $2.01B $9.91M $3.91B
EPS (diluted) $5.61 $0.38 $17.26
Cash & equivalents $1.29B $29.47M $6.14B
Total debt $7.29B $74.86M –
Shares (diluted) 148.70M 58.35M 255.20M
Enterprise value $24.00B $173.43M $104.01B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIIBKMDAVRTX
P/E 44.7x 21.0x 30.0x
P/FCF 13.8x 17.6x 34.8x
P/Operating cash flow 13.0x 13.0x 30.7x
P/S 3.7x 2.4x 10.5x
P/B 2.0x 1.7x 6.5x
P/Tangible book 7.0x 1.7x 6.7x
EV/EBITDA 23.4x 9.3x 24.8x
EV/EBIT 42.9x 14.4x 26.0x
EV/Revenue 4.3x 2.1x 9.9x
EV/FCF 16.1x 15.2x 32.7x
EV/Operating cash flow 15.1x 11.2x 28.9x
PEG (3Y EPS CAGR) -1.37 0.30 2.96

Growth

14 metrics
MetricBIIBKMDAVRTX
Revenue growth (1Y) 0.3% 13.2% 10.2%
Revenue CAGR (3Y) 0.2% 9.6% 9.8%
Gross profit growth (1Y) -1.6% 5.9% 10.1%
Gross profit CAGR (3Y) -1.1% 12.9% 9.0%
Operating income growth (1Y) -43.7% 10.3% 21.8%
Operating income CAGR (3Y) -31.3% 43.1% 6.4%
Net income growth (1Y) -45.5% 17.0% 21.1%
Net income CAGR (3Y) -32.1% 258.5% 9.4%
EPS growth (1Y) -46.2% 14.5% 22.9%
EPS CAGR (3Y) -32.6% 70.4% 10.1%
Operating cash flow growth (1Y) 36.0% -10.9% 11.6%
Operating cash flow CAGR (3Y) 26.3% 5.6% 1.8%
Free cash flow growth (1Y) 36.3% -16.7% 8.5%
Free cash flow CAGR (3Y) 33.0% 1.0% -0.7%

Profitability

14 metrics
MetricBIIBKMDAVRTX
Gross margin 74.0% 40.8% 86.0%
EBITDA margin 18.5% 22.5% 39.7%
Operating margin 10.1% 14.5% 38.0%
Pretax margin 10.1% 13.9% 41.9%
Net margin 8.3% 11.5% 35.0%
FCF margin 26.9% 13.7% 30.2%
Operating cash flow margin 28.7% 18.6% 34.1%
Return on equity 4.5% 8.4% 22.2%
Return on assets 2.7% 5.8% 16.3%
Return on invested capital 3.3% 10.2% –
Return on capital employed 3.8% 8.3% 20.8%
Asset turnover 0.3x 0.5x 0.5x
Cash conversion (OCF / net income) 3.4x 1.6x 1.0x
Stock comp / revenue 3.0% 1.1% 5.5%

Financial Health

11 metrics
MetricBIIBKMDAVRTX
Debt / assets 22.7% 1.6% –
Debt / equity 0.4x 0.0x –
Net debt / EBITDA 3.2x -1.5x –
Debt / FCF 2.7x 0.2x –
Liabilities / assets 41.3% 29.6% 26.2%
Equity / assets 58.7% 70.4% 73.8%
Interest coverage – 93.7x –
Current ratio 1.9x 4.1x 3.2x
Quick ratio 1.1x 2.3x 2.5x
Cash ratio 0.3x 1.4x 2.0x
Altman Z-score 3.15 3.60 13.25

Shareholder Returns

7 metrics
MetricBIIBKMDAVRTX
Dividend yield – 5.2% –
Net buyback yield – 0.0% 1.4%
Shareholder yield – 5.2% 1.4%
Payout ratio (earnings) – 129.6% –
Payout ratio (FCF) – 109.6% –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIIBKMDAVRTX
Forward P/E 19.7xFY2026 16.1xFY2026 28.6xFY2026
EPS, next fiscal year $12.81FY2026 $0.50FY2026 $18.24FY2026
EPS growth, next FY -16.2%FY2026 +38.9%FY2026 -0.9%FY2026
EPS growth, the year after +36.5% +24.0% +23.0%
Revenue, next fiscal year $9.96BFY2026 $209.90MFY2026 $12.67BFY2026
Revenue growth, next FY +0.7%FY2026 +16.3%FY2026 +5.8%FY2026
Revenue growth, the year after +11.9% +13.6% +18.8%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIIBKMDAVRTX
Held by institutions 96.4% 8.6% 95.1%
Institutions holding 1,036 50 1,745
Change in shares held, QoQ +6.0% -3.1% +3.9%
Institutions buying 548 24 902
Institutions selling 294 18 605
Buyers to sellers 1.86 1.33 1.49

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIIBKMDAVRTX
BIIB 1.00 0.05 0.48
KMDA 0.05 1.00 0.16
VRTX 0.48 0.16 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BIIB, KMDA and VRTX?

Vertex Pharmaceuticals (VRTX) is the largest by market capitalisation: Biogen (BIIB) $37.34B, Kamada (KMDA) $464.37M, Vertex Pharmaceuticals (VRTX) $132.00B.

Which stock is cheaper, BIIB, KMDA and VRTX?

Kamada (KMDA) trades on the lowest price-to-earnings ratio (Biogen (BIIB) 44.7x, Kamada (KMDA) 21.0x, Vertex Pharmaceuticals (VRTX) 30.0x). On next year's consensus earnings, Kamada (KMDA) is cheapest (Biogen (BIIB) 19.7x, Kamada (KMDA) 16.1x, Vertex Pharmaceuticals (VRTX) 28.6x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Kamada (KMDA) grew revenue fastest over the trailing twelve months: Biogen (BIIB) +0.3%, Kamada (KMDA) +13.2%, Vertex Pharmaceuticals (VRTX) +10.2%.

Which company is more profitable?

Vertex Pharmaceuticals (VRTX) has the highest net margin (Biogen (BIIB) 8.3%, Kamada (KMDA) 11.5%, Vertex Pharmaceuticals (VRTX) 35.0%). On return on invested capital, Kamada (KMDA) leads (Biogen (BIIB) 3.3%, Kamada (KMDA) 10.2%).

Which stock has performed better?

Over the past year Biogen (BIIB) returned the most: Biogen (BIIB) +68.0%, Kamada (KMDA) +14.5%, Vertex Pharmaceuticals (VRTX) +24.0%. Over five years, Vertex Pharmaceuticals (VRTX) compounded fastest (Biogen (BIIB) -0.9%/yr, Kamada (KMDA) +7.0%/yr, Vertex Pharmaceuticals (VRTX) +23.4%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Kamada (KMDA) 5.22%. Biogen (BIIB) and Vertex Pharmaceuticals (VRTX) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Vertex Pharmaceuticals (VRTX) has been the steadiest (Biogen (BIIB) 34.0%, Kamada (KMDA) 34.7%, Vertex Pharmaceuticals (VRTX) 29.0%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIIB, KMDA and VRTX?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Kamada (KMDA) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.