BIIB vs KMDA vs MDGL Stock Comparison

Biogen, Kamada and Madrigal Pharmaceuticals Prices as of Oct 28, 2026 Peers: Industry group
BIIB Biogen Inc.
$244.05 +6.7% 1M +63.6% 1Y
Market cap
$36.08B
P/E
103.8x
Revenue (TTM)
$10.30B
Div. yield
–
Biotechnology Healthcare
3 wins
KMDA Kamada Ltd
$8.00 -7.2% 1M +15.1% 1Y
Market cap
$461.49M
P/E
20.9x
Revenue (TTM)
$191.85M
Div. yield
5.25%
Biotechnology Healthcare
6 wins

Head to Head

11 decided of 12

Kamada leads on 6 of the 12 questions below (Kamada 6, Biogen 3, Madrigal Pharmaceuticals 2). Which ones matter depends on what you are buying for; a cheap multiple and slow growth often come together.

QuestionBIIBKMDAMDGLLeader
Larger companyMarket capitalisation $36.08B $461.49M $12.56B BIIB
Cheaper on earningsLower P/E, profitable companies only 103.8x 20.9x -38.6x KMDA
Cheaper on forward earningsLower price / next fiscal year consensus EPS 19.1x 16.0x — KMDA
Faster revenue growthRevenue growth, trailing twelve months +2.3% +13.2% +149.0% MDGL
More profitableNet margin, trailing twelve months 3.4% 11.5% -25.3% KMDA
Better return on capitalReturn on invested capital 1.3% 10.2% — KMDA
Less leveragedLower net debt / EBITDA 4.5x -1.5x 1.6x KMDA
Higher dividend yieldTrailing dividend yield — 5.25% — –
Better 1-year returnPrice return, last 12 months +63.6% +15.1% +0.4% BIIB
Better 5-year returnAnnualised price return, 5 years -1.8%/yr +7.0%/yr +40.9%/yr MDGL
Less volatileAnnualised volatility, 1 year 34.2% 34.7% 43.5% BIIB
Higher overall scoreMean of the five percentile scores vs peers 59/100 84/100 66/100 KMDA

Percentile Scorecard

BIIBKMDAMDGL

Each axis is the mean percentile of its metrics against the company's industry group. 100 is the best in the group, 50 the middle.

Scores by Axis

AxisBIIBKMDAMDGL
Valuation 92 #54 of 625 97 #21 of 625 74 #164 of 625
Growth 26 #446 of 602 71 #177 of 602 69 #190 of 602
Profitability 87 #73 of 549 87 #70 of 549 74 #143 of 549
Financial Health 33 #437 of 654 74 #168 of 654 41 #388 of 654
Shareholder Returns – 90 #38 of 367 75 #93 of 367
Overall 59 84 66
  • BIIB ranked among 672 companies in Pharmaceuticals and Biotechnology
  • KMDA ranked among 672 companies in Pharmaceuticals and Biotechnology
  • MDGL ranked among 672 companies in Pharmaceuticals and Biotechnology

Price Performance

Price return, split-adjusted, before dividends. Click a name to hide or show it.

Returns

PeriodBIIBKMDAMDGLSPY
1 month +6.7%-7.2%-16.6% +0.9%
3 months +16.6%+14.1%-21.2% +5.9%
6 months +25.6%-1.4%-16.9% +8.5%
Year to date +38.7%+13.3%-26.0% +13.3%
1 year +63.6%+15.1%+0.4% +12.4%
3 years +4.1%+93.2%+258.0% +88.1%
3 years, per year +1.3%+24.6%+53.0% +23.5%
5 years -8.5%+40.1%+454.3% +68.2%
5 years, per year -1.8%+7.0%+40.9% +11.0%
10 years -14.0%+34.5%+2,459.4% +263.4%
10 years, per year -1.5%+3.0%+38.3% +13.8%

Risk

MeasureBIIBKMDAMDGLSPY
Volatility, 1Y 34.2%34.7%43.5% 12.7%
Downside volatility, 1Y 32.7%33.2%41.5% 12.7%
Beta vs S&P 500, 1Y 0.251.010.30 1.00
Return / volatility, 1Y 1.860.440.01 0.98
Max drawdown, 5Y -64.4%-44.4%-61.4% -25.4%
From 52-week high -3.9%-14.1%-28.5% -0.9%
52-week high $253.84$9.31$602.83 $779.14
52-week low $147.86$6.62$412.35 $631.97

Valuation History

Weekly multiples on trailing twelve-month fundamentals. Negative or extreme readings (a loss year, a collapsed denominator) are left out so the chart stays readable.

MultipleBIIBKMDAMDGL
P/E now vs peer median 103.8xmedian 17.4x 20.9xmedian 17.4x -38.6xmedian 17.4x
P/S now vs peer median 3.5xmedian 9.1x 2.4xmedian 9.1x 9.8xmedian 9.1x
EV/EBITDA now vs peer median 31.7xmedian 17.1x 9.2xmedian 17.1x -37.8xmedian 17.1x
P/FCF now vs peer median 17.4xmedian 19.0x 17.5xmedian 19.0x -60.9xmedian 19.0x
P/B now vs peer median 1.9xmedian 2.2x 1.7xmedian 2.2x 24.0xmedian 2.2x
PEG now vs peer median -2.70median 0.34 0.30median 0.34 -2.62median 0.34

Financial History

Reported figures by fiscal period, placed on the calendar year (or quarter) each period ended in, so companies with different fiscal years line up.

Trailing twelve monthsBIIBKMDAMDGL
Revenue $10.30B $191.85M $1.28B
Gross profit $7.62B $78.31M –
Operating income $445.10M $27.83M -$322.62M
Net income $347.50M $22.25M -$325.11M
Free cash flow $2.07B $26.32M -$206.29M
R&D $2.15B $9.91M $490.14M
EPS (diluted) $2.35 $0.38 $-11.15
Cash & equivalents $1.30B $29.47M $292.73M
Total debt $7.29B $74.86M $340.79M
Shares (diluted) 147.80M 58.35M 29.15M
Enterprise value $25.39B $170.55M $8.82B

All Metrics

58 metrics · best in bold

Bold marks the best reading: the lowest positive value for multiples, leverage and payout, the highest for everything else. The bar under each value is its percentile against that company's own peers. Hover a value for its rank and the peer median.

Valuation

12 metrics
MetricBIIBKMDAMDGL
P/E 103.8x 20.9x -38.6x
P/FCF 17.4x 17.5x -60.9x
P/Operating cash flow 16.1x 12.9x -63.5x
P/S 3.5x 2.4x 9.8x
P/B 1.9x 1.7x 24.0x
P/Tangible book 6.5x 1.7x 24.3x
EV/EBITDA 31.7x 9.2x -37.8x
EV/EBIT 94.5x 14.3x -37.4x
EV/Revenue 4.1x 2.1x 9.4x
EV/FCF 20.3x 15.1x -58.5x
EV/Operating cash flow 18.7x 11.1x -61.0x
PEG (3Y EPS CAGR) -2.70 0.30 -2.62

Growth

14 metrics
MetricBIIBKMDAMDGL
Revenue growth (1Y) 2.3% 13.2% 149.0%
Revenue CAGR (3Y) 1.0% 9.6% –
Gross profit growth (1Y) 0.6% 5.9% –
Gross profit CAGR (3Y) 0.5% 12.9% –
Operating income growth (1Y) -76.6% 10.3% -4.1%
Operating income CAGR (3Y) -34.8% 43.1% 0.8%
Net income growth (1Y) -78.4% 17.0% -15.3%
Net income CAGR (3Y) -38.1% 258.5% 0.5%
EPS growth (1Y) -78.5% 14.5% 12.1%
EPS CAGR (3Y) -38.5% 70.4% 14.8%
Operating cash flow growth (1Y) -8.4% -10.9% 35.7%
Operating cash flow CAGR (3Y) 18.2% 5.6% 10.6%
Free cash flow growth (1Y) -10.1% -16.7% 33.1%
Free cash flow CAGR (3Y) 24.9% 1.0% 9.4%

Profitability

14 metrics
MetricBIIBKMDAMDGL
Gross margin 74.0% 40.8% –
EBITDA margin 12.9% 22.5% -24.9%
Operating margin 4.3% 14.5% -25.1%
Pretax margin 4.3% 13.9% -24.8%
Net margin 3.4% 11.5% -25.3%
FCF margin 20.1% 13.7% -16.1%
Operating cash flow margin 21.8% 18.6% -15.4%
Return on equity 1.8% 8.4% -59.8%
Return on assets 1.1% 5.8% -25.8%
Return on invested capital 1.3% 10.2% –
Return on capital employed 1.6% 8.3% -37.4%
Asset turnover 0.3x 0.5x 1.0x
Cash conversion (OCF / net income) 6.5x 1.6x 0.6x
Stock comp / revenue 2.9% 1.1% 9.5%

Financial Health

11 metrics
MetricBIIBKMDAMDGL
Debt / assets 22.7% 1.6% 27.4%
Debt / equity 0.4x 0.0x 0.7x
Net debt / EBITDA 4.5x -1.5x 1.6x
Debt / FCF 3.5x 0.2x -1.7x
Liabilities / assets 41.0% 29.6% 57.9%
Equity / assets 59.0% 70.4% 42.1%
Interest coverage – 93.7x -10.2x
Current ratio 1.9x 4.1x 3.2x
Quick ratio 0.9x 2.3x 2.8x
Cash ratio 0.3x 1.4x 2.2x
Altman Z-score 3.07 3.58 8.90

Shareholder Returns

7 metrics
MetricBIIBKMDAMDGL
Dividend yield – 5.3% –
Net buyback yield – 0.0% -0.3%
Shareholder yield – 5.2% -0.3%
Payout ratio (earnings) – 129.6% –
Payout ratio (FCF) – 109.6% –
Dividend growth (1Y) – – –
Dividend CAGR (3Y) – – –

Analyst Estimates

Solid lines are reported fiscal-year results; dashed lines are the consensus for the years ahead. Hover a year for the analysts' high and low, and how each result compared with its estimate.

ConsensusBIIBKMDAMDGL
Forward P/E 19.1xFY2026 16.0xFY2026 –
EPS, next fiscal year $12.81FY2026 $0.50FY2026 $-6.25FY2026
EPS growth, next FY -16.2%FY2026 +38.9%FY2026 –
EPS growth, the year after +36.5% +24.0% –
Revenue, next fiscal year $9.96BFY2026 $209.90MFY2026 $1.46BFY2026
Revenue growth, next FY +0.7%FY2026 +16.3%FY2026 +52.7%FY2026
Revenue growth, the year after +11.9% +13.6% +36.3%

Institutional Ownership

13F filings, quarter ended Jun 30, 2026
HoldersBIIBKMDAMDGL
Held by institutions 96.4% 8.6% 80.9%
Institutions holding 1,036 50 412
Change in shares held, QoQ +6.0% -3.1% -0.6%
Institutions buying 548 24 225
Institutions selling 294 18 128
Buyers to sellers 1.86 1.33 1.76

Return Correlation

Daily returns, last 12 months

1.00 means two stocks move in lockstep, 0 that they move independently. Pairs below about 0.5 diversify each other.

BIIBKMDAMDGL
BIIB 1.00 0.05 0.13
KMDA 0.05 1.00 0.10
MDGL 0.13 0.10 1.00

Add a Peer

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Frequently Asked Questions

Which is bigger, BIIB, KMDA and MDGL?

Biogen (BIIB) is the largest by market capitalisation: Biogen (BIIB) $36.08B, Kamada (KMDA) $461.49M, Madrigal Pharmaceuticals (MDGL) $12.56B.

Which stock is cheaper, BIIB, KMDA and MDGL?

Kamada (KMDA) trades on the lowest price-to-earnings ratio (Biogen (BIIB) 103.8x, Kamada (KMDA) 20.9x, Madrigal Pharmaceuticals (MDGL) -38.6x). On next year's consensus earnings, Kamada (KMDA) is cheapest (Biogen (BIIB) 19.1x, Kamada (KMDA) 16.0x). A lower multiple can reflect slower expected growth, so read it next to the growth figures.

Which company is growing faster?

Madrigal Pharmaceuticals (MDGL) grew revenue fastest over the trailing twelve months: Biogen (BIIB) +2.3%, Kamada (KMDA) +13.2%, Madrigal Pharmaceuticals (MDGL) +149.0%.

Which company is more profitable?

Kamada (KMDA) has the highest net margin (Biogen (BIIB) 3.4%, Kamada (KMDA) 11.5%, Madrigal Pharmaceuticals (MDGL) -25.3%). On return on invested capital, Kamada (KMDA) leads (Biogen (BIIB) 1.3%, Kamada (KMDA) 10.2%).

Which stock has performed better?

Over the past year Biogen (BIIB) returned the most: Biogen (BIIB) +63.6%, Kamada (KMDA) +15.1%, Madrigal Pharmaceuticals (MDGL) +0.4%. Over five years, Madrigal Pharmaceuticals (MDGL) compounded fastest (Biogen (BIIB) -1.8%/yr, Kamada (KMDA) +7.0%/yr, Madrigal Pharmaceuticals (MDGL) +40.9%/yr). Returns are price only, before dividends.

Which pays a higher dividend?

Only one of these companies pays a dividend: Kamada (KMDA) 5.25%. Biogen (BIIB) and Madrigal Pharmaceuticals (MDGL) pays no regular dividend.

Which stock is riskier?

By one-year price volatility, Biogen (BIIB) has been the steadiest (Biogen (BIIB) 34.2%, Kamada (KMDA) 34.7%, Madrigal Pharmaceuticals (MDGL) 43.5%). Volatility measures how widely the price swings, not the risk of the business.

Which is the better stock, BIIB, KMDA and MDGL?

There is no single answer; it depends on what you are buying for. On the 12 head-to-head measures on this page, Kamada (KMDA) leads on 6. Business Quant does not give investment advice; use the comparison as a starting point for your own research.

Data from SEC filings, exchange prices and consensus estimates, via Business Quant. Percentile scores compare each company with its own peer group, so two companies' scores are each relative to different peers unless you rank against the whole market. Price returns exclude dividends. Nothing on this page is investment advice.